Research Topics
Species | Aimee M HunterSummaryAffiliation: University of California Country: USA Publications
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Publications
Stressor controllability and learned helplessness research in the United States: sensitization and fatigue processesThomas R Minor
Department of Psychology, UCLA Los Angeles, 90095 1563, USA
Integr Physiol Behav Sci 37:44-58. 2002..The substrates of adaptive behavior are removed; performance deficits ensue...- The promise of the quantitative electroencephalogram as a predictor of antidepressant treatment outcomes in major depressive disorderAimee M Hunter
Laboratory of Brain, Behavior, and Pharmacology, Semel Institute for Neuroscience and Human Behavior at UCLA, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA 90024 1759, USA
Psychiatr Clin North Am 30:105-24. 2007.... 
Antidepressant response trajectories and quantitative electroencephalography (QEEG) biomarkers in major depressive disorderAimee M Hunter
Semel Institute for Neuroscience and Human Behavior at UCLA, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA 90024 1759, United States
J Psychiatr Res 44:90-8. 2010..Statistical methods such as GMM are needed to identify clinically relevant symptom response trajectories...- The antidepressant treatment response index and treatment outcomes in a placebo-controlled trial of fluoxetineAimee M Hunter
Laboratory of Brain, Behavior, and Pharmacology, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, California 90024 1759, USA
J Clin Neurophysiol 28:478-82. 2011..Importantly, ATR index did not correlate significantly with placebo outcomes. Results extend ATR index findings to include predictive validity with fluoxetine, suggesting that this biomarker has specificity for drug effects... 
Brain functional changes (QEEG cordance) and worsening suicidal ideation and mood symptoms during antidepressant treatmentA M Hunter
Semel Institute for Neuroscience and Human Behavior at UCLA, Los Angeles, CA 90024 1759, USA
Acta Psychiatr Scand 122:461-9. 2010..We examined the quantitative electroencephalographic (QEEG) cordance biomarker of brain function biomarker in relation to treatment-emergent symptom worsening...- Brain functional changes during placebo lead-in and changes in specific symptoms during pharmacotherapy for major depressionA M Hunter
Laboratory of Brain, Behavior, and Pharmacology, Semel Institute for Neuroscience and Human Behavior at UCLA, 760 Westwood Plaza, Rm 37 359, Los Angeles, CA 90024 1759, USA
Acta Psychiatr Scand 119:266-73. 2009.... - Changes in brain function (quantitative EEG cordance) during placebo lead-in and treatment outcomes in clinical trials for major depressionAimee M Hunter
Semel Institute for Neuroscience and Human Behavior at UCLA, 760 Westwood Plaza, Rm 37 359, Los Angeles, CA 90024 1759, USA
Am J Psychiatry 163:1426-32. 2006..The authors hypothesized that decreases in prefrontal cordance during the placebo lead-in phase would be associated with better clinical outcome in subjects treated with antidepressants... - Neurophysiologic correlates of side effects in normal subjects randomized to venlafaxine or placeboAimee M Hunter
Behavioral Pharmacology Laboratory, Department of Psychiatry and Biobehavioral Sciences, UCLA Neuropsychiatric Institute, David Geffen School of Medicine, Los Angeles, CA 90024 1759, USA
Neuropsychopharmacology 30:792-9. 2005..Results of these exploratory hypothesis-generating analyses should be considered tentative until replicated... - Helplessness and escape performance: glutamate-adenosine interactions in the frontal cortexAimee M Hunter
Department of Psychology, University of California, Los Angeles 90095 1563, USA
Behav Neurosci 117:123-35. 2003..These findings are consistent with the involvement of N-methyl-D-aspartate receptor activation in the frontal cortex in the helplessness effect... - Midline and right frontal brain function as a physiologic biomarker of remission in major depressionIan A Cook
UCLA Depression Research and Clinic Program, Semel Institute for Neuroscience and Human Behavior at UCLA, Los Angeles, CA, United States
Psychiatry Res 174:152-7. 2009..These results suggest that remission may be predictable from physiologic measurements after 1 week of treatment, and that this region merits further investigation in the neurobiology of treatment response... - Changes in brain function during administration of venlafaxine or placebo to normal subjectsAndrew F Leuchter
Laboratory of Brain, Behavior, and Pharmacology, Semel Institute for Neuroscience and Human Behavior at UCLA, Los Angeles, CA 90024 1759, USA
Clin EEG Neurosci 39:175-81. 2008..Future studies should examine other classes of medication, as well as antidepressants with other mechanisms of action, to determine if cordance detects antidepressant medication effects in general in normal subjects... - Rostral anterior cingulate cortex activity and early symptom improvement during treatment for major depressive disorderAlexander S Korb
Labrotory of Brain, Behavior, and Pharmacology, and the UCLA Depression Research for Clinic Program, Semel Institute for Neuroscience and Human Behavior at UCLA, Los Angeles, CA, USA
Psychiatry Res 192:188-94. 2011..The model examining the mOFC showed a trend in the three-way interaction. A combination of pretreatment rACC activity and early symptom improvement may be useful for predicting treatment response... - Does prior antidepressant treatment of major depression impact brain function during current treatment?Aimee M Hunter
Laboratory of Brain, Behavior, and Pharmacology, and the Depression Research and Clinic Program, Semel Institute for Neuroscience and Human Behavior, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, UCLA, Los Angeles, CA 90024 1759, United States
Eur Neuropsychopharmacol 22:711-20. 2012..Results suggest that prefrontal brain functional changes during treatment for MDD may differ depending upon prior treatment with antidepressant medication... - Brain functional changes and duloxetine treatment response in fibromyalgia: a pilot studyAimee M Hunter
Laboratory of Brain, Behavior, and Pharmacology, Semel Institute for Neuroscience and Human Behavior at the University of California, Los Angeles, CA, USA
Pain Med 10:730-8. 2009..We hypothesized that cordance might also predict response to antidepressant medications for symptoms of FMS... - Rostral anterior cingulate cortex theta current density and response to antidepressants and placebo in major depressionAlexander S Korb
Laboratory of Brain, Behavior, and Pharmacology, Semel Institute for Neuroscience and Human Behavior at UCLA, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA 90024 1759, USA
Clin Neurophysiol 120:1313-9. 2009.... - Brain electrical source differences between depressed subjects and healthy controlsAlexander S Korb
Laboratory of Brain, Behavior, and Pharmacology, Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior at UCLA, David Geffen School of Medicine at UCLA, Los Angeles, CA 90024 1759, USA
Brain Topogr 21:138-46. 2008..Inconsistent findings among LORETA studies, and between LORETA studies and those using other functional imaging techniques, may result from differences in electrode montages... - A new paradigm for the prediction of antidepressant treatment responseAndrew F Leuchter
Laboratory of Brain Behavior, and Pharmacology, Semel Institute for Neuroscience and Human Behavior at UCLA, Los Angeles, CA 90024, USA
Dialogues Clin Neurosci 11:435-46. 2009..We posit that this new paradigm could lead to earlier recovery from depressive illness and ultimately produce profound health and economic benefits... - Quantitative electroencephalogram biomarkers for predicting likelihood and speed of achieving sustained remission in major depression: a report from the biomarkers for rapid identification of treatment effectiveness in major depression (BRITE-MD) trialIan A Cook
UCLA Semel Institute for Neuroscience and Human Behavior, Depression Research and Clinic Program and Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
J Clin Psychiatry 74:51-6. 2013.... - Monoamine oxidase a and catechol-o-methyltransferase functional polymorphisms and the placebo response in major depressive disorderAndrew F Leuchter
Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, 760 Westwood Plaza, Rm 37 452, Los Angeles, CA 90024 1759, USA
J Clin Psychopharmacol 29:372-7. 2009..These findings support the hypothesis that genetic polymorphisms modulating monoaminergic tone are related to degree of placebo responsiveness in major depressive disorder... - Amygdala lateralization at rest and during viewing of neutral faces in major depressive disorder using low-resolution brain electromagnetic tomographyHaleh Farahbod
Semel Institute for Neuroscience and Human Behavior at UCLA, Los Angeles, CA 90024 1759, USA
Clin EEG Neurosci 41:19-23. 2010..Findings suggest a more pronounced lateralization effect in normal healthy controls than in MDD subjects when changing from a resting (eyes-closed) condition to viewing faces without emotional valence... - Biomarkers to predict antidepressant responseAndrew F Leuchter
Semel Institute for Neuroscience and Human Behavior at UCLA, David Geffen School of Medicine at UCLA, Los Angeles, CA 90024, USA
Curr Psychiatry Rep 12:553-62. 2010..Once such biomarkers are validated, they could form the basis of new paradigms for antidepressant treatment selection... - Resting-state quantitative electroencephalography reveals increased neurophysiologic connectivity in depressionAndrew F Leuchter
Laboratory of Brain, Behavior, and Pharmacology, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, United States of America
PLoS ONE 7:e32508. 2012..These results can inform the development of qEEG state and trait biomarkers for MDD... - Growth modeling with nonignorable dropout: alternative analyses of the STAR*D antidepressant trialBengt Muthen
Muthén and Muthén, Los Angeles, California 90066, USA
Psychol Methods 16:17-33. 2011..The analyses provide a new way to assess drug efficiency in the presence of dropout...