Ming Szu Hung

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Identification of hematein as a novel inhibitor of protein kinase CK2 from a natural product library
    Ming Szu Hung
    Thoracic Oncology Laboratory, Department of Surgery, Comprehensive Cancer Center, University of California, San Francisco, CA 94115, USA
    BMC Cancer 9:135. 2009
  2. pmc Functional polymorphism of the CK2alpha intronless gene plays oncogenic roles in lung cancer
    Ming Szu Hung
    Thoracic Oncology Laboratory, Department of Surgery, Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 5:e11418. 2010
  3. pmc Cul4A is an oncogene in malignant pleural mesothelioma
    Ming Szu Hung
    Thoracic Oncology Laboratory, Department of Surgery, Comprehensive Cancer Center, University of California, San Francisco, CA 94115, USA
    J Cell Mol Med 15:350-8. 2011
  4. pmc Hematein, a casein kinase II inhibitor, inhibits lung cancer tumor growth in a murine xenograft model
    Ming Szu Hung
    Thoracic Oncology Laboratory, Department of Surgery, Comprehensive Cancer Center, University of California, San Francisco, CA 94115, USA
    Int J Oncol 43:1517-22. 2013
  5. pmc Frizzled-8 receptor is activated by the Wnt-2 ligand in non-small cell lung cancer
    Dawn T Bravo
    Department of Surgery, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94115, USA
    BMC Cancer 13:316. 2013
  6. pmc Transgenic mice for cre-inducible overexpression of the Cul4A gene
    Tong Li
    Thoracic Oncology Laboratory, Department of Surgery, Comprehensive Cancer Center, University of California, San Francisco, California 94143, USA
    Genesis 49:134-41. 2011

Collaborators

Detail Information

Publications6

  1. pmc Identification of hematein as a novel inhibitor of protein kinase CK2 from a natural product library
    Ming Szu Hung
    Thoracic Oncology Laboratory, Department of Surgery, Comprehensive Cancer Center, University of California, San Francisco, CA 94115, USA
    BMC Cancer 9:135. 2009
    ..To date, there is no small molecular CK2 inhibitor in clinical trial yet. With the aim to identify novel CK2 inhibitors, we screened a natural product library...
  2. pmc Functional polymorphism of the CK2alpha intronless gene plays oncogenic roles in lung cancer
    Ming Szu Hung
    Thoracic Oncology Laboratory, Department of Surgery, Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 5:e11418. 2010
    ..These results are consistent with an important role for the 398T allele of the CSNK2A1P in human lung cancer susceptibility...
  3. pmc Cul4A is an oncogene in malignant pleural mesothelioma
    Ming Szu Hung
    Thoracic Oncology Laboratory, Department of Surgery, Comprehensive Cancer Center, University of California, San Francisco, CA 94115, USA
    J Cell Mol Med 15:350-8. 2011
    ..Our study indicates that Cul4A amplification and overexpression play an oncogenic role in the pathogenesis of mesothelioma. Thus, Cul4A may be a potential therapeutic target for MPM...
  4. pmc Hematein, a casein kinase II inhibitor, inhibits lung cancer tumor growth in a murine xenograft model
    Ming Szu Hung
    Thoracic Oncology Laboratory, Department of Surgery, Comprehensive Cancer Center, University of California, San Francisco, CA 94115, USA
    Int J Oncol 43:1517-22. 2013
    ..Molecular docking showed that hematein binds to CK2α in durable binding sites. Collectively, our results suggest that hematein is an allosteric inhibitor of protein kinase CK2 and has antitumor activity to lung cancer. ..
  5. pmc Frizzled-8 receptor is activated by the Wnt-2 ligand in non-small cell lung cancer
    Dawn T Bravo
    Department of Surgery, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94115, USA
    BMC Cancer 13:316. 2013
    ....
  6. pmc Transgenic mice for cre-inducible overexpression of the Cul4A gene
    Tong Li
    Thoracic Oncology Laboratory, Department of Surgery, Comprehensive Cancer Center, University of California, San Francisco, California 94143, USA
    Genesis 49:134-41. 2011
    ..This mouse model provides a valuable resource for investigating the significance of Cul4A overexpression in various tissues...