Research Topics
| Philippe HujoelSummaryAffiliation: University of Washington Country: USA Publications
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Publications
A hidden periodontitis epidemic during the 20th century?P P Hujoel
Department of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle, WA 98195, USA
Community Dent Oral Epidemiol 31:1-6. 2003..The goal of this study was to impute how the secular changes in smoking prevalence during the 20th century impacted the advanced periodontitis incidence in the US...
Long-term use of medications and destructive periodontal diseasePhilippe P Hujoel
Department of Dental Public Health Sciences, University of Washington, Seattle, WA 98195 7475, USA
J Periodontol 79:1330-8. 2008..Knowledge of typical medication use among patients with chronic periodontitis or destructive periodontal disease is limited. The aim of this study was to associate periodontitis severity with the use of different classes of medications...
Head-and-neck organ doses from an episode of orthodontic carePhilippe Hujoel
Department of Dental Public Health Sciences and Epidemiology, School of Dentistry, University of Washington, Seattle, WA 98195 7475, USA
Am J Orthod Dentofacial Orthop 133:210-7. 2008..In this study, we estimated secular changes (1963-2003) in age-specific organ doses associated with orthodontic care and collective organ doses in the United States in 1999...
The impact of drug samples on clinical recommendations in dental educationPhilippe P Hujoel
Department of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle, WA 98195 7475, USA
J Dent Educ 75:1323-8. 2011..08-0.35; p<0.0001). We conclude that branded drug samples in a dental education setting were associated with increasing brand recommendation, narrowing therapeutic thinking, and decreased consideration for removing causes...
Oral health-related quality of life of periodontal patientsJ Cunha-Cruz
Department of Dental Public Health Sciences, University of Washington, Seattle 98195 7475, USA
J Periodontal Res 42:169-76. 2007..Self-assessments of oral health were associated with clinical characteristics...
Antepartum dental radiography and infant low birth weightPhilippe P Hujoel
Department of Dental Public Health Sciences, University of Washington, Seattle, WA 98195, USA
JAMA 291:1987-93. 2004..It is unclear if radiation affects the hypothalamus-pituitary-thyroid axis and thereby indirectly birth weight, or if the radiation directly affects the reproductive organs...
Radiographs associated with one episode of orthodontic therapyPhilippe Hujoel
Department of Dental Public Health Sciences, University of Washington, School of Dentistry, Box 357475, Seattle, WA 98195, USA
J Dent Educ 70:1061-5. 2006..The substantial variability in radiographic practices in orthodontics could be reduced by research into clinical utility and by establishing guidelines...
Spurious associations in oral epidemiological research: the case of dental flossing and obesityP P Hujoel
Department of Dental Public Health Sciences, University of Washington, Seattle, WA 98195, USA
J Clin Periodontol 33:520-3. 2006..Such associations between oral and general health awareness has the potential to induce spurious associations in oral epidemiological research...
Dental flossing and interproximal caries: a systematic reviewP P Hujoel
Department of Dental Public Health Sciences, University of Washington, Seattle, WA 98195, USA
J Dent Res 85:298-305. 2006..These findings should be extrapolated to more typical floss-users with care, since self-flossing has failed to show an effect...
Mercury exposure from dental filling placement during pregnancy and low birth weight riskP P Hujoel
Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA 98195 7475, USA
Am J Epidemiol 161:734-40. 2005..00, 95% confidence interval: 0.27, 3.68). This study found no evidence that mercury-containing dental fillings placed during pregnancy increased low-birth-weight risk...
Infant formula and enamel fluorosis: a systematic reviewPhilippe P Hujoel
Department of Dental Public Health Sciences, School of Dentistry, University of Washington, 1959 N E Pacific St, B 509, Box 357475, Seattle, WA 98195 7475, USA
J Am Dent Assoc 140:841-54. 2009..S. population. The authors conducted a systematic review of controlled studies regarding the risk of developing enamel fluorosis associated with use of infant formula...
Does chronic periodontitis cause coronary heart disease? A review of the literatureP P Hujoel
Department of Dental Public Health Sciences, School of Dentistry, Department of Epidemiology, Box 357475, University of Washington, Seattle, Wash 98195, USA
J Am Dent Assoc 133:31S-36S. 2002..Chronic periodontitis, or CP, has been associated with coronary heart disease, or CHD. This article reviews the available prospective CP-CHD evidence...
Evaluating the burst hypothesis at a site-specific level using the lack-of-fit testP P Hujoel
Department of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle 98195, USA
J Periodontol 69:357-62. 1998..We conclude that the lack-of-fit test will reliably reject the linear model at a site-specific level only if true disease progresses in such a fashion that a handful of sudden changes leads to a tooth mortality event...
The informativeness of attachment loss on tooth mortalityP P Hujoel
Department of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle 98195, USA
J Periodontol 70:44-8. 1999..The goal of this study was to evaluate the first criterion: Are serial clinical attachment loss measurements informative on overall tooth mortality?..
Retinal and gingival hemorrhaging and chronic hyperglycemiaPhilippe P Hujoel
Department of Epidemiology, School of Public Health, University of Washington, Seattle, Washington, USA
Diabetes Care 34:181-3. 2011..To assess the hypothesis that retinopathies are indicative of systemic microvascular injury...
Dietary carbohydrates and dental-systemic diseasesP Hujoel
Department of Dental Public Health Sciences, Box 357475, School of Dentistry, University of Washington, Seattle, WA 98195 7475, USA
J Dent Res 88:490-502. 2009..These opposing dietary hypotheses have increasingly been put to the test in clinical trials. The emerging trial results favor Cleave-Yudkin's hypothesis and may affect preventive approaches for dental and systemic diseases...
Non-surgical periodontal therapy and tooth loss. A cohort studyP P Hujoel
Department of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle 98195, USA
J Periodontol 71:736-42. 2000..The primary objective of this study was to assess the association between tooth loss and the non-surgical periodontal treatment history of 1,021 members of the Kaiser Permanente Dental Care Program...
Cessation of periodontal care during pregnancy: effect on infant birthweightPhilippe P Hujoel
Department of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle, 98195, USA
Eur J Oral Sci 114:2-7. 2006..Periodontal care patterns, in and of themselves, were unrelated to low-birthweight risk...
The dentogingival epithelial surface area revisitedP P Hujoel
Department of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle 98195, USA
J Periodontal Res 36:48-55. 2001..It was concluded that the mean DGES among individuals with periodontitis ranges from 8 cm2 to 20 cm2, considerably smaller than the range of 50 cm2 to 200 cm2 currently assumed...
Examining the link between coronary heart disease and the elimination of chronic dental infectionsP P Hujoel
Department of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle 98195, USA
J Am Dent Assoc 132:883-9. 2001....
Pre-existing cardiovascular disease and periodontitis: a follow-up studyP P Hujoel
Department of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle 98195, USA
J Dent Res 81:186-91. 2002..66; 95% CI, 0.42-1.05). It is concluded that periodontitis or gingivitis does not elevate CHD risk among individuals with a prior heart attack or self-reported pre-existing cardiovascular disease...
Activation time and material stiffness of sequential removable orthodontic appliances. Part 2: Dental improvementsKaren Michelle Clements
Department of Orthodontics, School of Dentistry, University of Washington, Box 357446, Seattle, WA 98195, USA
Am J Orthod Dentofacial Orthop 124:502-8. 2003..A statistically significant decrease in mean average papillary bleeding score was found during treatment when compared with pretreatment scores, although this difference was not clinically significant...
Measures of dental disease occurrenceP P Hujoel
Department of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle 98195
Community Dent Oral Epidemiol 19:252-6. 1991..No new concepts are introduced, but the choice of the unit of analysis of numerator and denominator is discussed, and the biological interpretation of the within-patient correlation coefficient is discussed...
Activation time and material stiffness of sequential removable orthodontic appliances. Part 1: Ability to complete treatmentAnne Marie Bollen
Department of Orthodontics, School of Dentistry, University of Washington, Box 357446, Seattle, WA 98195, USA
Am J Orthod Dentofacial Orthop 124:496-501. 2003..This exploratory study suggests that subjects with a 2-week activation regimen, no extractions, and a low PAR score are more likely to complete their initial series of aligners...
Fractal dimension on dental radiographsA M Bollen
Department of Orthodontics, University of Washington, Seattle, Washington 98195, USA
Dentomaxillofac Radiol 30:270-5. 2001..This study confirms other reports that FD increases when bone mass decreases. In addition, it suggests that panoramic radiographs can be used as a possible alternative for the measurement of FD to periapical radiographs...
Statin use and tooth loss in chronic periodontitis patientsJ Cunha-Cruz
Department of Dental Public Health Sciences, University of Washington, Seattle, 98195-7475, USA
J Periodontol 77:1061-6. 2006..Exploration of these findings in additional epidemiological studies may be worthwhile...
Total body weight and waist circumference associated with chronic periodontitis among adolescents in the United StatesAnne F Reeves
Primary, Maternal, and Child Health Program, Department of Health Services, School of Dentistry, University of Washington, Seattle, USA
Arch Pediatr Adolesc Med 160:894-9. 2006..To investigate whether measures of obesity are associated with periodontitis...
Secular trends in socio-economic disparities in edentulism: USA, 1972-2001J Cunha-Cruz
Department of Dental Public Health Sciences, University of Washington, B509, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195 7475, USA
J Dent Res 86:131-6. 2007..In conclusion, the absolute prevalence difference in edentulism between low and high socio-economic positions has remained unchanged over the last three decades...
Efficiency issues among statistical methods for demonstrating efficacy of caries preventionL A Mancl
Department of Dental Public Health Sciences, University of Washington, Seattle 98195 7475, USA
J Dent Res 83:C95-8. 2004..Incorporating the number of surfaces at risk, the surface time at risk, and surface-specific characteristics will typically produce only a modest gain in efficiency...
Caries prevention in a community-dwelling older populationL V Powell
Department of Restorative Dentistry, University of Washington, Seattle, Wash 98195, USA
Caries Res 33:333-9. 1999..09) and 23% for root caries events (p = 0.15), when compared to the groups that received no intraoral procedures (groups 1 and 2). Routine preventive treatments may have had only a small-to-moderate effect upon caries development...
Systemic antibiotics and tooth loss in periodontal diseaseJ Cunha-Cruz
University of Washington, Dental Public Health Sciences, B509, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195 7475, USA
J Dent Res 87:871-6. 2008..Long-term, larger randomized trials are needed to provide evidence that antibiotics reduce tooth loss when used in the management of destructive periodontal disease...
Bias induced by self-reported smoking on periodontitis-systemic disease associationsC F Spiekerman
Department of Dental Public Health Sciences, Box 357475, University of Washington School of Dentistry, Seattle 98195, USA
J Dent Res 82:345-9. 2003..Future studies should report results of analyses on separate subcohorts of never-smokers and smokers...
The cost-effectiveness of interleukin-1 genetic testing for periodontal diseaseMitchell K Higashi
Pharmaceutical Outcomes Research and Policy Program, University of Washington, Seattle 98195-7630, USA
J Periodontol 73:1474-84. 2002..However, the model demonstrates that three clinical parameters are highly influential in determining if IL-1 testing can be implemented in a primary care setting in a cost-effective manner...
An ABCD program to increase access to dental care for children enrolled in Medicaid in a rural countyTarja Kaakko
Department of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle 98195, USA
J Public Health Dent 62:45-50. 2002..ABCD children had fewer teeth with initial caries. The average incremental cost per child per initial lesion prevented was 31.44 dollars. CONCLUSION: ABCD most benefited the youngest cohort of children and improved health...
The smoking-periodontitis association in developing nationsPhilippe Hujoel
Department of Dental Public Health Sciences, B-509 School of Dentistry University of Washington1959 NE Pacific Street, Box 357475 Seattle, WA 98195, USA
Community Dent Oral Epidemiol 31:158; author reply 159-60. 2003
Osteoporosis and implant failure: an exploratory case-control studyW Becker
University of Southern California, School of Dentistry, Department of Periodontology, Los Angeles, USA
J Periodontol 71:625-31. 2000..Osteoporosis has been suggested as a risk factor for implant failure, but data supporting such a link are limited...
Cross-sectional study of periodontal care and Glycosylated Hemoglobin in an insured populationLeslie Spangler
Group Health Research Institute, Seattle, Washington, USA
Diabetes Care 33:1753-8. 2010..Compare GHb among people with diabetes who have and have not received periodontal care...
Converting science into art: the challenge of the translationistsPhilippe Hujoel
Department of Dental Public Health Sciences, University of Washington, Seattle, WA, USA
J Evid Based Dent Pract 8:176-80. 2008..Translating basic science evidence into clinical trials is particularly challenging...
Preparing practicing dentists to engage in practice-based researchTimothy A DeRouen
Department of Dental Public Health Sciences, University of Washington, Seattle 98195 7480, USA
J Am Dent Assoc 139:339-45. 2008....
The effects of orthodontic therapy on periodontal health: a systematic review of controlled evidenceAnne Marie Bollen
Department of Orthodontics, School of Dentistry, University of Washington, Box 357446, Seattle, Washington 98195, USA
J Am Dent Assoc 139:413-22. 2008..The objective of the authors' systematic review was to compare contemporary orthodontic treatment with no intervention, by means of evaluating periodontal outcomes measured after end of treatment...
Secular trends in preadult orthodontic care in the United States: 1942-2002Anne Marie Bollen
Department of Orthodontics, School of Dentistry, University of Washington, Seattle, Wash 98195, USA
Am J Orthod Dentofacial Orthop 132:579-85. 2007..The goals of this study were to describe secular trends in preadult orthodontic care for people in the United States born between 1942 and 1972, and to estimate the number of new preadult orthodontic treatment starts in 2006...
Response to BrentPhilippe P Hujoel
Health Phys 89:395-7. 2005
Are statins associated with decreased tooth loss in chronic periodontitis?Barry G Saver
Department of Family Medicine, University of Washington, Seattle, WA, USA
J Clin Periodontol 34:214-9. 2007..To evaluate whether statin use was associated with decreased tooth loss among patients with chronic periodontitis...
Dental care use and self-reported dental problems in relation to pregnancyMona T Lydon-Rochelle
Department of Family and Child Nursing, School of Nursing, University of Washington, Mailstop 357262, Seattle, WA 98195 7262, USA
Am J Public Health 94:765-71. 2004..We examined the relationships between risk factors amenable to intervention and the likelihood of dental care use during pregnancy...
Personal oral hygiene and chronic periodontitis: a systematic reviewPhilippe P Hujoel
Department of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle, Washington, USA
Periodontol 2000 37:29-34. 2005
Number of teeth and residual alveolar ridge height in subjects with a history of self-reported osteoporotic fracturesAnne Marie Bollen
Department of Orthodontics, School of Dentistry, University of Washington, Box 357446, Seattle, WA 98195, USA
Osteoporos Int 15:970-4. 2004..The clinical implication is that a history of osteoporotic fractures is not an important cause for tooth loss and residual ridge resorption in an elderly dental-school population...
Abnormal pocket depth and gingival recession as distinct phenotypesPhilippe P Hujoel
Department of Dental Public Health Sciences and Department of Epidemiology, School of Dentistry, University of Washington, Seattle, Washington, USA
Periodontol 2000 39:22-9. 2005
Response to direct and indirect recruitment for a randomised dental clinical trial in a multicultural population of eldersMichael I Macentee
Faculty of Dentistry, University of British Columbia, Vancouver, Canada
Community Dent Oral Epidemiol 30:377-81. 2002..The goal of this study was to report on our experiences with direct and indirect recruitment methods for a trial to prevent tooth loss in elders...
Endpoints in periodontal trials: the need for an evidence-based research approachPhilippe P Hujoel
Department of Dental Public Health Sciences, Scool of Dentistry, University of Washington, Seattle, U.S.A
Periodontol 2000 36:196-204. 2004
An exploration of the periodontitis-cancer associationPhilippe P Hujoel
Department of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle, WA 98195, USA
Ann Epidemiol 13:312-6. 2003..Despite these apparent unconfounded associations, there are reasons to believe that the periodontitis-cancer associations may be spurious...
Destructive periodontal disease and tobacco and cannabis smokingPhilippe P Hujoel
JAMA 299:574-5. 2008
Research Grants
- The Effectiveness of Treatment for Adult PeriodontitisPhilippe Hujoel; Fiscal Year: 2006..This information can help determine in what area of periodontal research definitive clinical trials may offer the greatest contribution. ..
