Michael G Hughes

Summary

Affiliation: University of Virginia
Country: USA

Publications

  1. ncbi request reprint E2 quasispecies specificity of hepatitis C virus association with allografts immediately after liver transplantation
    Michael G Hughes
    University of Virginia, Department of Surgery, Surgical Infectious Disease Laboratory, Charlottesville, VA, USA
    Liver Transpl 10:208-16. 2004
  2. ncbi request reprint Does prior transfusion worsen outcomes from infection in surgical patients?
    Michael G Hughes
    Department of Surgery, Surgical Infectious Disease Laboratory, University of Virginia, Charlottesville, Virginia 22908, USA
    Surg Infect (Larchmt) 4:335-43. 2003
  3. ncbi request reprint Comparison of fungal and nonfungal infections in a broad-based surgical patient population
    Michael G Hughes
    Department of Surgery, Surgical Infectious Disease Laboratory, University of Virginia, Charlottesville, Virginia 22908, USA
    Surg Infect (Larchmt) 6:55-64. 2005
  4. ncbi request reprint HCV infection of the transplanted liver: changing CD81 and HVR1 variants immediately after liver transplantation
    Michael G Hughes
    Department of Surgery, Surgical Infectious Disease Laboratory, University of Virginia, Charlottesville, Virginia, USA
    Am J Transplant 5:2504-13. 2005
  5. ncbi request reprint Effect of an intensive care unit rotating empiric antibiotic schedule on the development of hospital-acquired infections on the non-intensive care unit ward
    Michael G Hughes
    Department of Surgery, University of Virginia, Charlottesville 22908, USA
    Crit Care Med 32:53-60. 2004
  6. doi request reprint Does body mass index affect infection-related outcomes in the intensive care unit?
    Robert L Smith
    Department of Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    Surg Infect (Larchmt) 8:581-8. 2007
  7. ncbi request reprint Cost of Gram-negative resistance
    Heather L Evans
    Department of Surgery, University of Virginia Health System, Charlottesville, VA, USA
    Crit Care Med 35:89-95. 2007
  8. ncbi request reprint Primary human hepatocytes in spheroid formation to study hepatitis C infection
    Tae W Chong
    Department of Surgery, Surgical Infectious Disease Laboratory, University of Virginia, Charlottesville, Virginia 22908, USA
    J Surg Res 130:52-7. 2006
  9. doi request reprint The impact of recipient obesity on outcomes after renal transplantation
    Robert M Cannon
    University of Louisville, Department of Surgery, Division of Transplantation, Louisville, KY 40202, USA
    Ann Surg 257:978-84. 2013
  10. ncbi request reprint Nature of gram-negative rod antibiotic resistance during antibiotic rotation
    Heather L Evans
    Surgical Infectious Disease Research Laboratory, Department of Surgery, UVA Health System, Charlottesville, VA 22908 1380, USA
    Surg Infect (Larchmt) 6:223-31. 2005

Detail Information

Publications20

  1. ncbi request reprint E2 quasispecies specificity of hepatitis C virus association with allografts immediately after liver transplantation
    Michael G Hughes
    University of Virginia, Department of Surgery, Surgical Infectious Disease Laboratory, Charlottesville, VA, USA
    Liver Transpl 10:208-16. 2004
    ..02 and P = 0.04, respectively). Immediately after transplantation but before actual infection, liver allografts select out from the infecting serum inoculum a less heterogeneous, more closely related population of quasispecies variants...
  2. ncbi request reprint Does prior transfusion worsen outcomes from infection in surgical patients?
    Michael G Hughes
    Department of Surgery, Surgical Infectious Disease Laboratory, University of Virginia, Charlottesville, Virginia 22908, USA
    Surg Infect (Larchmt) 4:335-43. 2003
    ..The objective of this study was to determine the effect of transfusion on outcomes among infected surgical patients...
  3. ncbi request reprint Comparison of fungal and nonfungal infections in a broad-based surgical patient population
    Michael G Hughes
    Department of Surgery, Surgical Infectious Disease Laboratory, University of Virginia, Charlottesville, Virginia 22908, USA
    Surg Infect (Larchmt) 6:55-64. 2005
    ..Our aim was to compare fungal and nonfungal infections among a diverse surgical patient population...
  4. ncbi request reprint HCV infection of the transplanted liver: changing CD81 and HVR1 variants immediately after liver transplantation
    Michael G Hughes
    Department of Surgery, Surgical Infectious Disease Laboratory, University of Virginia, Charlottesville, Virginia, USA
    Am J Transplant 5:2504-13. 2005
    ..In conclusion, HVR1 quasispecies variants differentially associate with, and infect allografts, after liver transplantation. Additionally, allografts express variable amounts of CD81 after transplantation...
  5. ncbi request reprint Effect of an intensive care unit rotating empiric antibiotic schedule on the development of hospital-acquired infections on the non-intensive care unit ward
    Michael G Hughes
    Department of Surgery, University of Virginia, Charlottesville 22908, USA
    Crit Care Med 32:53-60. 2004
    ..We hypothesized that this intervention would decrease infectious complications in the non-ICU ward to which these patients were transferred...
  6. doi request reprint Does body mass index affect infection-related outcomes in the intensive care unit?
    Robert L Smith
    Department of Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    Surg Infect (Larchmt) 8:581-8. 2007
    ..We hypothesized that increasing BMI would be an independent predictor of higher mortality rates in the surgical/trauma ICU...
  7. ncbi request reprint Cost of Gram-negative resistance
    Heather L Evans
    Department of Surgery, University of Virginia Health System, Charlottesville, VA, USA
    Crit Care Med 35:89-95. 2007
    ..We wished to test the hypothesis that rGNR infections are associated with higher resource utilization...
  8. ncbi request reprint Primary human hepatocytes in spheroid formation to study hepatitis C infection
    Tae W Chong
    Department of Surgery, Surgical Infectious Disease Laboratory, University of Virginia, Charlottesville, Virginia 22908, USA
    J Surg Res 130:52-7. 2006
    ..As hepatocytes are the primary reservoir for the virus in vivo, we report on a model using primary human hepatocytes cultured in spheroid formation...
  9. doi request reprint The impact of recipient obesity on outcomes after renal transplantation
    Robert M Cannon
    University of Louisville, Department of Surgery, Division of Transplantation, Louisville, KY 40202, USA
    Ann Surg 257:978-84. 2013
    ..This study was undertaken to determine the effect of recipient obesity on delayed graft function (DGF) and graft survival after renal transplantation...
  10. ncbi request reprint Nature of gram-negative rod antibiotic resistance during antibiotic rotation
    Heather L Evans
    Surgical Infectious Disease Research Laboratory, Department of Surgery, UVA Health System, Charlottesville, VA 22908 1380, USA
    Surg Infect (Larchmt) 6:223-31. 2005
    ..The aim of this study was to characterize the evolution of gram-negative antibiotic resistance during a study of empiric antibiotic rotation...
  11. ncbi request reprint Contact isolation in surgical patients: a barrier to care?
    Heather L Evans
    Department of Surgery, UVA Health System, Charlottesville, VA 22908, USA
    Surgery 134:180-8. 2003
    ..Contact isolation is commonly used to prevent transmission of resistant organisms. We hypothesized that contact isolation negatively impacts the amount of direct patient care...
  12. doi request reprint A review of the United States experience with combined heart-liver transplantation
    Robert M Cannon
    Division of Transplantation, Department of Surgery, University of Louisville, Louisville, KY 40202, USA
    Transpl Int 25:1223-8. 2012
    ..4%, 71.0%, 65.1%; Pā€ƒ=ā€ƒ0.894) and heart transplantation alone (82.6%, 71.9%, 63.2%; Pā€ƒ=ā€ƒ0.341). CHLT is a safe and effective procedure, with graft survival rates similar to isolated heart and isolated liver transplantation...
  13. doi request reprint BK viral disease in renal transplantation
    Robert M Cannon
    Division of Transplantation, Department of Surgery, University of Louisville, Louisville, Kentucky, USA
    Curr Opin Organ Transplant 16:576-9. 2011
    ..This review is meant to highlight the literature on BK viral disease following renal transplantation published in the most recent year...
  14. doi request reprint Long-term outcome in 42 pediatric liver transplant patients with alpha 1-antitrypsin deficiency: a single-center experience
    Michael G Hughes
    Division of Transplantation, Department of Surgery, University of Minnesota, Minneapolis, MN, USA
    Clin Transplant 25:731-6. 2011
    ..We examined the long-term outcome of transplantation for alpha 1-antitrypsin deficiency (A1ATD)...
  15. pmc Transduction of human T cells with a novel T-cell receptor confers anti-HCV reactivity
    Yi Zhang
    Division of Transplantation, Department of Surgery, Medical University of South Carolina, Hollings Cancer Center, Charleston, South Carolina, USA
    PLoS Pathog 6:e1001018. 2010
    ..HCV TCR-transduced T cells may be promising for the treatment of patients with chronic HCV infections...
  16. doi request reprint Can preemptive cytomegalovirus monitoring be as effective as universal prophylaxis when implemented as the standard of care in patients at moderate risk?
    John W McGillicuddy
    Department of Surgery, Medical University of South Carolina, Charleston, SC, USA
    Transplantation 89:1218-23. 2010
    ....
  17. pmc Human liver transplantation as a model to study hepatitis C virus pathogenesis
    Michael G Hughes
    Department of Surgery, Medical University of South Carolina, Charleston, SC, USA
    Liver Transpl 15:1395-411. 2009
    ..Moreover, consideration is given to current and emerging antiviral therapeutic approaches based on translational research results...
  18. ncbi request reprint General surgery morning report: a competency-based conference that enhances patient care and resident education
    Brendon M Stiles
    Department of Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    Curr Surg 63:385-90. 2006
    ..Although initially oriented toward transfer of patient information, MR is also hypothesized to serve as a competency-based resident education tool...
  19. doi request reprint The effect of warm-up on high-intensity, intermittent running using nonmotorized treadmill ergometry
    Peter I Brown
    School of Science and Technology, Nottingham Trent University, Nottingham, United Kingdom
    J Strength Cond Res 22:801-8. 2008
    ..However, repeated sprinting ability is significantly improved after both active and passive warm-ups compared to no warm-up...
  20. doi request reprint AMPK inactivation in mononuclear cells: a potential intracellular mechanism for exercise-induced immunosuppression
    Hannah Moir
    Cardiff School of Health Sciences, Centre for Biomedical Sciences, University of Wales Institute Cardiff, Cardiff, Wales CF5 2YB, UK
    Appl Physiol Nutr Metab 33:75-85. 2008
    ..Thus, we suggest that prolonged, repeated, high-intensity exercise that leads to clinically relevant immunosuppression may do so via AMPK inactivation within immune cells...