Millie Hughes-Fulford

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization
    Millie Hughes-Fulford
    Department of Research, Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    J Orthop Surg Res 6:8. 2011
  2. ncbi Arachidonic acid, an omega-6 fatty acid, induces cytoplasmic phospholipase A2 in prostate carcinoma cells
    Millie Hughes-Fulford
    Laboratory of Cell Growth, Mail Code 151F, Department of Medicine, Northern California Institute for Research and Education and Veterans Affairs Medical Center, University of California, San Francisco, CA 94121, USA
    Carcinogenesis 26:1520-6. 2005
  3. ncbi Fibroblast growth factor-2 is an immediate-early gene induced by mechanical stress in osteogenic cells
    Chai Fei Li
    Laboratory of Cell Growth, Northern California Institute for Research and Education, San Francisco, California, USA
    J Bone Miner Res 21:946-55. 2006
  4. ncbi Effects of fatty acids on endothelial cells: inflammation and monocyte adhesion
    S Marlene Grenon
    Division of Vascular and Endovascular Surgery, Veterans Affairs Medical Center, University of California, San Francisco, California 94121, USA
    J Surg Res 177:e35-43. 2012
  5. ncbi Lessons learned about spaceflight and cell biology experiments
    Millie Hughes-Fulford
    Northern California Institute for Research and Education, San Francisco, CA, USA
    J Gravit Physiol 11:105-9. 2004
  6. ncbi Signal transduction and mechanical stress
    Millie Hughes-Fulford
    Laboratory of Cell Growth, Department of Medicine, Veterans Affairs Medical Center, University of California, and Northern California Institute for Research and Education, San Francisco, CA 94121, USA
    Sci STKE 2004:RE12. 2004
  7. ncbi Arachidonic acid activates phosphatidylinositol 3-kinase signaling and induces gene expression in prostate cancer
    Millie Hughes-Fulford
    Department of Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 91421, USA
    Cancer Res 66:1427-33. 2006
  8. ncbi The Rel/NF-κB pathway and transcription of immediate early genes in T cell activation are inhibited by microgravity
    Tammy T Chang
    Department of Surgery, University of California, San Francisco, CA, USA
    J Leukoc Biol 92:1133-45. 2012
  9. ncbi Polyunsaturated fatty acids and peripheral artery disease
    S Marlene Grenon
    Division of Vascular and Endovascular Surgery, University of California, San Francisco, San Francisco, CA 94121, USA
    Vasc Med 17:51-63. 2012
  10. ncbi Nutritional supplements, COX-2 and IGF-1 expression in men on active surveillance for prostate cancer
    June M Chan
    Department of Urology, University of California San Francisco, 1450 3rd Street, San Francisco, CA 94158 9001, USA
    Cancer Causes Control 22:141-50. 2011

Detail Information

Publications13

  1. ncbi The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization
    Millie Hughes-Fulford
    Department of Research, Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    J Orthop Surg Res 6:8. 2011
    ..Here we describe the sequential roles of FGF-2 in inducing gene expression, cell growth and BMP-2 in gene expression and mineralization of bone...
  2. ncbi Arachidonic acid, an omega-6 fatty acid, induces cytoplasmic phospholipase A2 in prostate carcinoma cells
    Millie Hughes-Fulford
    Laboratory of Cell Growth, Mail Code 151F, Department of Medicine, Northern California Institute for Research and Education and Veterans Affairs Medical Center, University of California, San Francisco, CA 94121, USA
    Carcinogenesis 26:1520-6. 2005
    ..Since cPLA2 is upstream in the eicosanoid pathway, it may be a good alternative for a pharmaceutical target for the treatment of cancer...
  3. ncbi Fibroblast growth factor-2 is an immediate-early gene induced by mechanical stress in osteogenic cells
    Chai Fei Li
    Laboratory of Cell Growth, Northern California Institute for Research and Education, San Francisco, California, USA
    J Bone Miner Res 21:946-55. 2006
    ..The induction of fgf-2 is mediated by PKA and ERK pathways...
  4. ncbi Effects of fatty acids on endothelial cells: inflammation and monocyte adhesion
    S Marlene Grenon
    Division of Vascular and Endovascular Surgery, Veterans Affairs Medical Center, University of California, San Francisco, California 94121, USA
    J Surg Res 177:e35-43. 2012
    ..The objective of this study was to examine the effect of arachidonic acid (AA), an n-6 FA, and eicosapentanoic acid (EPA), an n-3 FA, on the interaction between monocytes and endothelial cells (ECs)...
  5. ncbi Lessons learned about spaceflight and cell biology experiments
    Millie Hughes-Fulford
    Northern California Institute for Research and Education, San Francisco, CA, USA
    J Gravit Physiol 11:105-9. 2004
    ..Finally, spaceflight experiments are rewarding and worth your effort and patience...
  6. ncbi Signal transduction and mechanical stress
    Millie Hughes-Fulford
    Laboratory of Cell Growth, Department of Medicine, Veterans Affairs Medical Center, University of California, and Northern California Institute for Research and Education, San Francisco, CA 94121, USA
    Sci STKE 2004:RE12. 2004
    ..Here, we examine the various types of stress and the sequential response of transduction pathways that result in changes in gene expression and the ensuing proliferation of osteoblasts...
  7. ncbi Arachidonic acid activates phosphatidylinositol 3-kinase signaling and induces gene expression in prostate cancer
    Millie Hughes-Fulford
    Department of Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 91421, USA
    Cancer Res 66:1427-33. 2006
    ..Taken together, the data suggest that arachidonic acid via conversion to PGE(2) plays an important role in stimulation of growth-related genes and proliferation via PI3K signaling and NF-kappaB translocation to the nucleus...
  8. ncbi The Rel/NF-κB pathway and transcription of immediate early genes in T cell activation are inhibited by microgravity
    Tammy T Chang
    Department of Surgery, University of California, San Francisco, CA, USA
    J Leukoc Biol 92:1133-45. 2012
    ..Results from these experiments indicate that μg was the causative factor for impaired T cell activation during spaceflight by inhibiting transactivation of key immediate early genes...
  9. ncbi Polyunsaturated fatty acids and peripheral artery disease
    S Marlene Grenon
    Division of Vascular and Endovascular Surgery, University of California, San Francisco, San Francisco, CA 94121, USA
    Vasc Med 17:51-63. 2012
    ..The evidence of beneficial effects specific to patients with peripheral artery disease (PAD) remains elusive, and is the focus of this review...
  10. ncbi Nutritional supplements, COX-2 and IGF-1 expression in men on active surveillance for prostate cancer
    June M Chan
    Department of Urology, University of California San Francisco, 1450 3rd Street, San Francisco, CA 94158 9001, USA
    Cancer Causes Control 22:141-50. 2011
    ....
  11. ncbi Can I take a space flight? Considerations for doctors
    S Marlene Grenon
    Division of Vascular and Endovascular Surgery, University of California, San Francisco, CA 94121, USA
    BMJ 345:e8124. 2012
    ..Commercial investment is bringing space tourism closer to reality. Marlene Grenon and colleagues: outline what doctors will need to know...
  12. ncbi Reduction of anabolic signals and alteration of osteoblast nuclear morphology in microgravity
    Millie Hughes-Fulford
    Northern California Institute for Research and Education, San Francisco, California, USA
    J Cell Biochem 99:435-49. 2006
    ..Life on this planet has evolved in a normal gravity field and these data suggest that gravity plays a significant role in regulation of osteoblast transcription...
  13. ncbi The role of signaling pathways in osteoblast gravity perception
    Millie Hughes-Fulford
    Lab of Cell Growth, Department of Veteran s Affairs Medical Center and University of California San Francisco, San Francisco, CA 94121, USA lab site www spacedu com
    J Gravit Physiol 9:P257-60. 2002
    ..The secondary signal may include growth factor related kinases such as ERK, p38 and JNK map kinase (MAPK) pathways. Experimental evidence suggests that normal osteoblast response to stress and sera requires normal earth gravity...