S Huerta

..abstract:..

..The critical concepts in the oncogenesis of rectal cancer are areas of dynamic progression and require constant assessment...

..The following discussion addresses possible strategies of investigation to increase patients achieving a complete obliteration of rectal tumors following neoadjuvant chemoradio therapies...

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..This article reviews the current evidence available to identify a molecular profile predictive of the best response to ionizing radiation...

..This report presents a summary of the current status of the molecular markers of colorectal cancer to establish a diagnosis, determine prognosis and chemoradiotherapeutic interventions, and assess relapse following curative surgery...

..In the present report, we investigated the apoptotic gene products that might account for colon cancer evasion of immune attack and chemoradioresistance-induced apoptosis...

..This study was undertaken to determine the feasibility of an inpatient low-calorie program for a substantial decrease of preoperative weight (>10 points in BMI) in superobese patients...

..In the present report, we discuss classic nitric oxide donors and their potential therapeutic roles as cytotoxic agents or chemo-radio or -immune-sensitizing compounds in the treatment of drug-resistant cancers...

..The present study assessed the degree to which comorbid conditions improved after bariatric surgery in veteran patients...

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..To identify, using tissue microarray (TMA), an immunohistochemical panel predictive of response to ionizing radiation (IR) in rectal cancer...

..This chapter describes colon cancer with emphasis on the molecular mechanisms that may lead to chemoradio-resistance of cells with cytotoxically induced DNA injury in rectal cancer...

..Altogether, these findings underscore the potential therapeutic application of NO donors and subtoxic chemotherapeutic drugs in the treatment of advanced colon cancer resistant to conventional chemotherapeutic agents...

..This study reviews the results of these trials and the current status of oxaliplatin as a radiosensitizing agent in the neoadjuvant management of rectal cancer...

..This study assessed whether preoperative weight loss resulted in favorable outcomes after open Roux-en Y gastric bypass (RYGB)...

..This review discusses the various ways to study apoptosis with specific assays, reagents, and molecules. The particular advantages and disadvantages of each method are reviewed...

..There are currently no data on management or prognostic factors of portal vein thrombosis after bariatric operations...

..The aim of this review is to provide the available evidence of the role of Smac/DIABLO in colon carcinogenesis...

..The purpose of this study was to develop a mathematical model that accurately estimates the rate and extent of weight loss following gastric bypass surgery...

..These conclusions are limited by potential selection and publication bias in the trials assessed for this analysis. These limitations can be resolved only by randomized control trials...

..8 times that in the LGJ cohort. Sensitivity analyses confirmed ES as the dominant strategy. In conclusion, ES is the preferred treatment for palliation of duodenal obstruction due to advanced upper gastrointestinal tract cancer...

..The purpose of this study was to assess the validity of these selection criteria...

..Laparoscopic techniques have emerged as a suitable approach for colon resection. This study determined and compared the outcomes of patients undergoing laparoscopic or open colectomy at United States academic centers...

..This study was undertaken to assess the radiosensitizing properties of the smac mimetic JP-1201 in radioresistant HT-29 colorectal cancer cells in vitro and established xenografts in SCID mice...

..The aim of this study was to seek an association between the control of type 2 diabetes mellitus (T2DM), as determined by hemoglobin A1c (HbA1c) levels, and the outcome of colorectal cancer (CRC)...

..The purpose of this study was to compare risk factors for the development of incisional versus organ/space infections in patients undergoing colorectal surgery...

..A variety of Smac mimetic types comprising peptides, polynucleotides, and compounds have been studied both in vitro and in vivo. This discussion addresses the current status of Smac mimetics in cancer research...

..Our results indicate that implementation of a clinical pathway for bariatric surgery reduces cost and improves quality of care in an academic institution...

..007; OR = 4.5) independently predicted distant metastasis, whereas preoperative carcinoembryonic antigen (P = 0.038; OR = 2.8) and patients undergoing an APR (P = 0.019; OR = 25) independently predicted mortality...

..Bowel perforation is a known risk factor of unknown etiology associated with the use of Avastin. In this report, the incidence, risk factors, typical presentation, and management of patients with this complication is described...

..Mechanisms of radioresistance in rectal cancer remain unclear...

..The aim of this study was to review our experience with bowel obstruction following LRYGBP, specifically examining its etiology and management and to strategize maneuvers to minimize this complication...

..Acute colonic obstruction because of advanced colonic malignancy is a surgical emergency...

..To determine factors affecting compliance of a follow-up colonoscopy in patients with previously diagnosed adenomatous colon polyps...

..A high index of suspicion for leaks in postoperative RYGB patients with tachycardia is required if patients are to have good outcomes when complications develop...

..Possible predictors of recurrence after elective umbilical hernia repair have not been defined clearly. The aim of this study was to determine factors that predict recurrence in patients after elective repair of umbilical hernias...

..NCAM-180 is the isoform found in colonocytes, and loss of expression is associated with clinically aggressive colon cancers...

..To evaluate the risk of gallbladder cancer (GBC) in patients with a porcelain gallbladder (PGB)...

..We hypothesized that patients receiving ropivacaine would report lower levels of morphine requirement and pain, would have shorter hospital stays, and would return to ambulating faster than patients in the control group...

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..Targeting these genes may increase chemotherapy effectiveness in advanced colon cancer and reduce toxicity in normal tissue...

..To determine preoperative risk factors predictive of adverse outcomes after gastric bypass surgery...

..The initial JIB was associated with low morbidity and no mortality, and the follow-up RYGB procedure was a technically simple operation that could be performed with few complications...

..CPAP is a useful modality for treating hypoventilation after RYGB without increasing the risk of developing postoperative anastomotic leaks...

..This procedure has the theoretical advantage that patients retain normal eating capacity and lose weight irrespective of their eating habits. However, vitamin deficiencies may develop because BPD causes malabsorption...

..This suggests that the components of this herbal mixture, either independently or in combination, acted in colon cancer, resulting in a drastic effect on tumor initiation and tumor progression...

..RESULTS:We found no difference in the complication rates between the 2 groups (Fisher exact test; P =.21). CONCLUSIONS: Our findings suggest that routine placement of an NGT after RYGB is unnecessary...

..We have previously shown that vitamin D supplementation diminishes polyp load; the lack of effect of an altered calcium diet seen here may be due to a disturbance in vitamin D homeostasis...

..Computed tomography and magnetic resonance imaging are the primary initial imaging modalities. Definitive diagnosis is typically made at the time of laparotomy following biopsy. Surgical resection is the mainstay of treatment...

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