Research Topics
| JAMES HUDZIAKSummaryAffiliation: University of Vermont Country: USA Publications
Research Grants
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Detail Information
Publications
Latent class analysis of Child Behavior Checklist attention problemsJ J Hudziak
Division of Human Genetics, Center for Children, Youth, and Families, University of Vermont College of Medicine, Burlington 05405, USA
J Am Acad Child Adolesc Psychiatry 38:985-91. 1999....- The genetic and environmental contributions to attention deficit hyperactivity disorder as measured by the Conners' Rating Scales--RevisedJames J Hudziak
Division of Behavioral Genetics, Department of Psychiatry, University of Vermont, Given B229, Burlington, VT 05405, USA
Am J Psychiatry 162:1614-20. 2005..These studies typically used DSM ADHD symptoms collected by telephone or interviews with mothers. The purpose of this study was to test the genetic architecture of ADHD by using the ADHD index from Conners' Rating Scales-Revised... - Individual differences in aggression: genetic analyses by age, gender, and informant in 3-, 7-, and 10-year-old Dutch twinsJ J Hudziak
Departments of Psychiatry and Medicine, Division of Human Genetics, Center for Children Youth and Families, University of Vermont, College of Medicine, Burlington Vermont 05405, USA
Behav Genet 33:575-89. 2003..Contributions of common (13%-27%) and unique (16%-31%) environment were small to moderate. There was some evidence of genetic dominance by teacher report for 10-year-old girls... - Genetic influences on childhood competencies: a twin studyJames J Hudziak
University of Vermont College of Medicine, Burlington, USA
J Am Acad Child Adolesc Psychiatry 42:357-63. 2003..To estimate genetic, environmental, and rater contrast influences on parental reports of Activities, Social, School, and Total Competence scales of the Child Behavior Checklist (CBCL)... - The role of phenotypes (diagnoses) in genetic studies of attention-deficit/hyperactivity disorder and related child psychopathologyJ J Hudziak
University of Vermont College of Medicine, Burlington, Vermont, USA
Child Adolesc Psychiatr Clin N Am 10:279-97, viii. 2001..As the taxonomic approach is refined, there may be more success in identifying genetic and environmental risks for attention-deficit/hyperactivity disorder (ADHD)... - A twin study of inattentive, aggressive, and anxious/depressed behaviorsJ J Hudziak
Psychiatry Department Division of Human Genetics, University of Vermont, College of Medicine, Burlington, USA
J Am Acad Child Adolesc Psychiatry 39:469-76. 2000..To estimate genetic, environmental, and rater contrast influences on parental report of Attention Problems (AP), Aggressive (Agg), and Anxious/Depressed (AxD) behaviors of 492 twin pairs assessed with the Child Behavior Checklist... - Latent class analysis shows strong heritability of the child behavior checklist-juvenile bipolar phenotypeRobert R Althoff
Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
Biol Psychiatry 60:903-11. 2006.... 
COMT Val158Met genotype as a risk factor for problem behaviors in youthMatthew D Albaugh
Vermont Center for Children, Youth, and Families, University of Vermont, College of Medicine, Burlington, VT 05401, USA
J Am Acad Child Adolesc Psychiatry 49:841-9. 2010..We hypothesized that youth carrying a Met allele would have greater average aggressive behavior scores, and that youth exhibiting Val-homozygosity would have greater average attention problems scores...- Multi-informant assessment of temperament in children with externalizing behavior problemsWilliam Copeland
Department of Psychology, University of Vermont, USA
J Clin Child Adolesc Psychol 33:547-56. 2004..Reward dependence, persistence, cooperativeness, and self-directedness displayed similar patterns of negative relations to emotional and behavioral scales and positive relations to intelligence, achievement, and competence... - The genetic architecture of neuroticism in 3301 Dutch adolescent twins as a function of age and sex: a study from the Dutch twin registerDavid C Rettew
Department of Psychiatry, University of Vermont College of Medicine, Bington, Vermont 05405, USA
Twin Res Hum Genet 9:24-9. 2006..The magnitude of the genetic component appears higher in the present sample of adolescents than in most studies of adults. The present study suggests that, in adolescence, different genes are expressed in boys and girls... - Exploring the boundary between temperament and generalized anxiety disorder: a receiver operating characteristic analysisDavid C Rettew
Department of Psychiatry, University of Vermont College of Medicine, 89 Beaumont Avenue, Given Building Room B227, Burlington, VT 05405, USA
J Anxiety Disord 20:931-45. 2006..These findings suggest that while there are strong associations between HA and GAD, high levels of HA are neither necessary nor sufficient in the formation of clinically significant anxiety symptoms... - Non-additive and additive genetic effects on extraversion in 3314 Dutch adolescent twins and their parentsDavid C Rettew
Department of Psychiatry, University of Vermont College of Medicine, 1 South Prospect Street, Arnold 3, Burlington, VT 05401, USA
Behav Genet 38:223-33. 2008..There was no evidence of non-random mating for extraversion in the parental generation. Results show that in addition to additive genetic influences, extraversion in adolescents is influenced by non-additive genetic factors... - Interactions between child and parent temperament and child behavior problemsDavid C Rettew
Department of Psychiatry, University of Vermont College of Medicine, Burlington, 05405, USA
Compr Psychiatry 47:412-20. 2006..In this study, we test the hypothesis that interactions between child and parent temperament dimensions predict levels of child psychopathology after controlling for the effects of these dimensions individually... - A dimensional approach to developmental psychopathologyJames J Hudziak
University of Vermont, Burlington, VT 05401, USA
Int J Methods Psychiatr Res 16:S16-23. 2007..Because dimensional approaches are already used widely as an alternative measure of psychopathology, we argue that there is reason to consider dimensionalizing some aspects of the DSM... - Adult outcomes of childhood dysregulation: a 14-year follow-up studyRobert R Althoff
University of Vermont College of Medicine, Burlington, USA
J Am Acad Child Adolesc Psychiatry 49:1105-16. 2010.... 
Latent profiles of temperament and their relations to psychopathology and wellnessDavid C Rettew
Department of Psychiatry, University of Vermont College of Medicine, Burlington, VT 05401, USA
J Am Acad Child Adolesc Psychiatry 47:273-81. 2008..To test for empirically defined temperament phenotypes and to investigate their associations with psychopathology and wellness...- Latent class analysis of the Child Behavior Checklist Obsessive-Compulsive ScaleRobert R Althoff
Department of Psychiatry, Vermont Center for Children, Youth, and Families, University of Vermont, Burlington, VT 05401, USA
Compr Psychiatry 50:584-92. 2009..Within-class odds ratios were higher than across-class odds ratios and were higher for monozygotic than dizygotic twins. We conclude that LCA identifies an OCS class and that class is highly heritable using across-twin comparisons... - Cross-informant agreement of the Dysregulation Profile of the Child Behavior ChecklistRobert R Althoff
The Vermont Center for Children, Youth, and Families at the Department of Psychiatry, University of Vermont College of Medicine, Burlington, VT 05401, United States
Psychiatry Res 178:550-5. 2010..Children in this class as identified by parental and youth reports have a very high risk for suicidal thoughts and behaviors... - Assessment of dysregulated children using the Child Behavior Checklist: a receiver operating characteristic curve analysisRobert R Althoff
Vermont Center for Children, Youth, and Families, University of Vermont College of Medicine, Burlington, VT 05401, USA
Psychol Assess 22:609-17. 2010..Therefore, the authors recommend renaming the CBCL-PTSP the Dysregulation Short Scale and provide some guidelines for the use of the CBCL-DP scale and the CBCL-PTSP in clinical practice... - The Obsessive Compulsive Scale of the Child Behavior Checklist predicts obsessive-compulsive disorder: a receiver operating characteristic curve analysisJames J Hudziak
Department of Psychiatry, University of Vermont, Given B229, Burlington, VT 05405, USA
J Child Psychol Psychiatry 47:160-6. 2006.... - Family, twin, adoption, and molecular genetic studies of juvenile bipolar disorderRobert R Althoff
Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
Bipolar Disord 7:598-609. 2005.... - Genetic and environmental contributions to the Child Behavior Checklist Obsessive-Compulsive Scale: a cross-cultural twin studyJames J Hudziak
Department of Psychiatry, University of Vermont, Burlington Vrije University, Amsterdam, The Netherlands
Arch Gen Psychiatry 61:608-16. 2004..Twin studies of obsessive-compulsive disorder have indicated a significant genetic component to its expression... - Associations between temperament and DSM-IV externalizing disorders in children and adolescentsDavid C Rettew
Department of Psychiatry, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
J Dev Behav Pediatr 25:383-91. 2004..The interaction NS x HA was related to the ADHD-only group. Future research is needed to determine the mechanism of these association... - Screening for DSM-IV externalizing disorders with the Child Behavior Checklist: a receiver-operating characteristic analysisJames J Hudziak
University of Vermont, Given Building, Room B229, Burlington, VT 05405, USA
J Child Psychol Psychiatry 45:1299-307. 2004..This study examines the diagnostic accuracy of the CBCL syndrome AS scales for predicting DSM-IV Attention Deficit-Hyperactivity Disorder (ADHD) and Oppositional Defiant Disorder with or without Conduct Disorder (ODD/CD)... - The genetic and environmental contributions to oppositional defiant behavior: a multi-informant twin studyJames J Hudziak
Department of Psychiatry, University of Vermont, Burlington 05405, USA
J Am Acad Child Adolesc Psychiatry 44:907-14. 2005..To estimate the genetic and environmental contributions to oppositional defiant behavior (ODB) from mother, father, and teacher report using the Conners Revised Short Forms in a large twin sample... - Prevalence and genetic architecture of Child Behavior Checklist-juvenile bipolar disorderJames J Hudziak
Department of Psychiatry, University of Vermont, Burlington 05405, USA
Biol Psychiatry 58:562-8. 2005.... - Symptoms versus impairment: the case for respecting DSM-IV's Criterion DMichael Gordon
Upstate Medical University, Department of Psychiatry, Syracuse, NY 13210, USA
J Atten Disord 9:465-75. 2006.... - The latent class structure of ADHD is stable across informantsRobert R Althoff
Department of Psychiatry, University of Vermont, Burlington, Vermont 05405, United States of America
Twin Res Hum Genet 9:507-22. 2006..Results from LCA using Dutch twins with the CRS show stability across informants suggesting that more stable phenotypes may be accessible for genotyping using a multi-informant approach... - Child Behavior Checklist Juvenile Bipolar Disorder (CBCL-JBD) and CBCL Posttraumatic Stress Problems (CBCL-PTSP) scales are measures of a single dysregulatory syndromeLynsay Ayer
Vermont Center for Children, Youth and Families, University of Vermont College of Medicine, VT, USA
J Child Psychol Psychiatry 50:1291-300. 2009..We hypothesized that the two scales may be indicators of a single syndrome related to dysregulated mood, attention, and behavior. We aimed to describe and identify the overlap between the CBCL-JBD profile and CBCL-PTSP scales... - Deficits in reciprocal social behavior in male twins: evidence for a genetically independent domain of psychopathologyJohn N Constantino
Department of Psychiatry, Washington University School of Medicine, Campus Box 8134, 660 South Euclid Avenue, St Louis, MO 63110, USA
J Am Acad Child Adolesc Psychiatry 42:458-67. 2003.... - Genetic and environmental covariation between autistic traits and behavioral problemsRosa A Hoekstra
Department of Biological Psychology, VU University, Amsterdam, The Netherlands
Twin Res Hum Genet 10:853-60. 2007..These results indicate that autistic traits have specific characteristics that are substantially genetically independent from other common but related behavioral domains such as social problems and withdrawn behavior... - Genetic and environmental contributions to stability in loneliness throughout childhoodMeike Bartels
Department of Biological Psychology, VU University, Amsterdam, The Netherlands
Am J Med Genet B Neuropsychiatr Genet 147:385-91. 2008.... - Longitudinal stability of the CBCL-juvenile bipolar disorder phenotype: A study in Dutch twinsDorret I Boomsma
Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
Biol Psychiatry 60:912-20. 2006..The purpose of this study is to assess the developmental stability of the CBCL-JBD phenotype across ages 7, 10, and 12 years in a large population-based twin sample and to examine its genetic architecture... - The CBCL predicts DSM bipolar disorder in children: a receiver operating characteristic curve analysisStephen V Faraone
Medical Genetics Research Program and Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY 13210, USA
Bipolar Disord 7:518-24. 2005..The CBCL-PBD profile on the Child Behavior Checklist (CBCL) has been consistently reported showing deviant findings on the Attention Problems, Aggressive Behavior, and Anxious-Depressed subscales... - Disentangling genetic, environmental, and rater effects on internalizing and externalizing problem behavior in 10-year-old twinsMeike Bartels
Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
Twin Res 7:162-75. 2004..Significant influences of additive genetic, shared environmental and unique environmental factors were found for internalizing and externalizing syndromes... - A study of parent ratings of internalizing and externalizing problem behavior in 12-year-old twinsMeike Bartels
Department of Biological Psychiatry, Vrije Universiteit, Room 1F 66, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands
J Am Acad Child Adolesc Psychiatry 42:1351-9. 2003..This study investigates two models that have been used to explain the agreement and disagreement between mothers and fathers in the ratings of their children... - Why more boys than girls with ADHD receive treatment: a study of Dutch twinsEske M Derks
Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
Twin Res Hum Genet 10:765-70. 2007..These findings have implications for the results of genetic studies that rely on referred samples, as these studies may give a distorted view of sex differences in the population... - Genetic and environmental influences on the relation between attention problems and attention deficit hyperactivity disorderEske M Derks
Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, Amsterdam, 1081 BT, The Netherlands
Behav Genet 38:11-23. 2008..The aim of the present study is to investigate the extent to which these instruments measure an underlying construct and to estimate the genetic and environmental influences on individual differences in ADHD... - Short- and long-term effects of child care on problem behaviors in a Dutch sample of twinsToos C E M van Beijsterveldt
Biological Psychology Department, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands
Twin Res Hum Genet 8:250-8. 2005..12 and .23). Children with a larger amount of child care did not show more behavior problems, therefore it was questioned whether the increased levels of behavior problems could be attributed to quantity of child care... - Influences on achieving motor milestones: a twin-singleton studySilvia I Brouwer
Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
Twin Res Hum Genet 9:424-30. 2006..Sex has minimal to no effect on motor development in early childhood. DZ twins achieve motor milestones sooner than MZ twins. Attainment of gross motor milestones (crawl, stand and walk) is delayed in later birth cohorts... - Contributions of parental alcoholism, prenatal substance exposure, and genetic transmission to child ADHD risk: a female twin studyValerie S Knopik
Center for Alcohol and Addiction Studies, Department of Community Health, Brown University Medical School, Providence, RI 02912, USA
Psychol Med 35:625-35. 2005..Little attention, however, has been directed to investigating the roles of genetic transmission and prenatal exposure simultaneously... - Genetic and environmental contributions underlying stability in childhood obsessive-compulsive behaviorDaniel S van Grootheest
Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
Biol Psychiatry 61:308-15. 2007..The objective of this study is to determine the developmental stability of pediatric OC behavior and the genetic and environmental influences on stability in a large population-based twin sample... - Genetic and environmental influences on cross-gender behavior and relation to behavior problems: a study of Dutch twins at ages 7 and 10 yearsC E M van Beijsterveldt
Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands
Arch Sex Behav 35:647-58. 2006..Cross-gender behavior was associated with higher scores on Internalizing and Externalizing problems, both in boys and in girls... - Attention problems and attention-deficit/hyperactivity disorder in discordant and concordant monozygotic twins: evidence of environmental mediatorsHanne Lehn
Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
J Am Acad Child Adolesc Psychiatry 46:83-91. 2007..To study familial and nonfamilial environmental influences on attention problems and attention-deficit/hyperactivity disorder (ADHD) in monozygotic twins discordant and concordant-high and low for these traits... - Netherlands Twin Register: from twins to twin familiesDorret I Boomsma
Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands
Twin Res Hum Genet 9:849-57. 2006..In this paper we give an update on the YNTR and ANTR phenotyping and on the ongoing ANTR biobank studies... - Genetically informative designs in the study of resilience in developmental psychopathologyMeike Bartels
Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands
Child Adolesc Psychiatr Clin N Am 16:323-39, viii. 2007..Extending this argument to the study of resilience (eg, why some kids recover) is the focus of last part this article and our research strategies in the next decade... - Young Netherlands Twin Register (Y-NTR): a longitudinal multiple informant study of problem behaviorMeike Bartels
Department of Biological Psychology, Vrije Univerisiteit Amsterdam, The Netherlands
Twin Res Hum Genet 10:3-11. 2007..In conclusion, between ages 3 and 12 genetic factors are the most important cause of individual differences in emotional and behavioral problems... - Assessment of motor milestones in twinsJacqueline M Langendonk
Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
Twin Res Hum Genet 10:835-9. 2007..From this work we conclude that data on achieving milestones can be reliably obtained through the mail using retrospective surveys when the children are 2 years of age... - Twins and the study of rater (dis)agreementMeike Bartels
Department of Biological Psychology, VU University
Psychol Methods 12:451-66. 2007..Rater-specific shared environmental factors show substantial influence on stability. This could mean that rater bias may be persistent and affect longitudinal studies... - Mission statement: advancing the science of pediatric mental health and promoting the care of youth and their familiesAndres Martin
J Am Acad Child Adolesc Psychiatry 47:1. 2008 - Genetic contributions to subtypes of aggressionLannie Ligthart
Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
Twin Res Hum Genet 8:483-91. 2005..54 for boys and .43 for girls). These findings may have implications for how aggressive behavior should be assessed in boys and girls... - Bupropion XL in adults with attention-deficit/hyperactivity disorder: a randomized, placebo-controlled studyTimothy E Wilens
Pediatric Psychopharmacology Research, Yawkey Center for Outpatient Care, Massachusetts General Hospital, Boston, Massachusetts 021143 3117, USA
Biol Psychiatry 57:793-801. 2005..This study evaluated the efficacy and safety of an extended-release, once-daily formulation of bupropion (XL) in the treatment of adults with ADHD...
Research Grants
- DEVELOPMENTAL TWIN STUDY: ATTENTION, AGGRESSION, AFFECTJAMES HUDZIAK; Fiscal Year: 2004..A long-term goal of this project is to continue to study these subjects in order to extend the study of genetic factors from childhood, across adolescence, and into adulthood. ..
- Determinants of Adolescent Exercise Behavior; towards Evidence-Based InterventionJames J Hudziak; Fiscal Year: 2010....