Larry D Hubbard

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. ncbi request reprint Early age-related maculopathy in the cardiovascular health study
    Ronald Klein
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin 53726, USA
    Ophthalmology 110:25-33. 2003
  2. doi request reprint Brightness, contrast, and color balance of digital versus film retinal images in the age-related eye disease study 2
    Larry D Hubbard
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Madison, Madison, Wisconsin 53711 1068, USA
    Invest Ophthalmol Vis Sci 49:3269-82. 2008
  3. ncbi request reprint Computer-assisted measurement of retinal vessel diameters in the Beaver Dam Eye Study: methodology, correlation between eyes, and effect of refractive errors
    Tien Yin Wong
    Department of Ophthalmology, University of Wisconsin, Madison, Wisconsin, USA
    Ophthalmology 111:1183-90. 2004
  4. doi request reprint Effect of image compression and resolution on retinal vascular caliber
    Thomas W Pauli
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Madison, Madison, WI 53717, USA
    Invest Ophthalmol Vis Sci 53:5117-23. 2012
  5. pmc Retinal vessel caliber among people with acquired immunodeficiency syndrome: relationships with disease-associated factors and mortality
    Sapna Gangaputra
    Fundus Photograph Reading Center, Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, USA
    Am J Ophthalmol 153:434-444.e1. 2012
  6. doi request reprint Transition from film to digital fundus photography in the Longitudinal Studies of the Ocular Complications of AIDS
    Sapna Gangaputra
    Fundus Photograph Reading Center, Department of Ophthalmology and Visual Sciences, University of Wisconsin Madison, Madison, Wisconsin 53717, USA
    Retina 32:600-5. 2012
  7. ncbi request reprint Revised formulas for summarizing retinal vessel diameters
    Michael D Knudtson
    Department of Ophthalmology, University of Wisconsin, Madison, WI 53726, USA
    Curr Eye Res 27:143-9. 2003
  8. doi request reprint Comparison of digital and film grading of diabetic retinopathy severity in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study
    Larry D Hubbard
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin 53717 0568, USA
    Arch Ophthalmol 129:718-26. 2011
  9. doi request reprint Monoscopic versus stereoscopic retinal photography for grading diabetic retinopathy severity
    Helen K Li
    Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch, Galveston, Texas 77555 1106, USA
    Invest Ophthalmol Vis Sci 51:3184-92. 2010
  10. doi request reprint Suboptimal image focus broadens retinal vessel caliber measurement
    Charles S Chandler
    Department of Ophthalmology and Visual Sciences, Fundus Photograph Reading Center, College of Engineering, Mechanical Engineering General, University of Wisconsin Madison, Madison, WI 53717, USA
    Invest Ophthalmol Vis Sci 52:8558-61. 2011

Detail Information

Publications49

  1. ncbi request reprint Early age-related maculopathy in the cardiovascular health study
    Ronald Klein
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin 53726, USA
    Ophthalmology 110:25-33. 2003
    ..To describe the prevalence of early age-related maculopathy (ARM) and its relation to atherosclerosis, lipids, hypertension, and inflammatory factors in a population studied for cardiovascular disease risk factors and outcomes...
  2. doi request reprint Brightness, contrast, and color balance of digital versus film retinal images in the age-related eye disease study 2
    Larry D Hubbard
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Madison, Madison, Wisconsin 53711 1068, USA
    Invest Ophthalmol Vis Sci 49:3269-82. 2008
    ....
  3. ncbi request reprint Computer-assisted measurement of retinal vessel diameters in the Beaver Dam Eye Study: methodology, correlation between eyes, and effect of refractive errors
    Tien Yin Wong
    Department of Ophthalmology, University of Wisconsin, Madison, Wisconsin, USA
    Ophthalmology 111:1183-90. 2004
    ....
  4. doi request reprint Effect of image compression and resolution on retinal vascular caliber
    Thomas W Pauli
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Madison, Madison, WI 53717, USA
    Invest Ophthalmol Vis Sci 53:5117-23. 2012
    ....
  5. pmc Retinal vessel caliber among people with acquired immunodeficiency syndrome: relationships with disease-associated factors and mortality
    Sapna Gangaputra
    Fundus Photograph Reading Center, Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, USA
    Am J Ophthalmol 153:434-444.e1. 2012
    ..To evaluate relationships between retinal vessel caliber, AIDS-related factors, and mortality...
  6. doi request reprint Transition from film to digital fundus photography in the Longitudinal Studies of the Ocular Complications of AIDS
    Sapna Gangaputra
    Fundus Photograph Reading Center, Department of Ophthalmology and Visual Sciences, University of Wisconsin Madison, Madison, Wisconsin 53717, USA
    Retina 32:600-5. 2012
    ..To describe the transition to digital imaging and assess any impact on ocular disease classification...
  7. ncbi request reprint Revised formulas for summarizing retinal vessel diameters
    Michael D Knudtson
    Department of Ophthalmology, University of Wisconsin, Madison, WI 53726, USA
    Curr Eye Res 27:143-9. 2003
    ....
  8. doi request reprint Comparison of digital and film grading of diabetic retinopathy severity in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study
    Larry D Hubbard
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin 53717 0568, USA
    Arch Ophthalmol 129:718-26. 2011
    ....
  9. doi request reprint Monoscopic versus stereoscopic retinal photography for grading diabetic retinopathy severity
    Helen K Li
    Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch, Galveston, Texas 77555 1106, USA
    Invest Ophthalmol Vis Sci 51:3184-92. 2010
    ..To assess agreement between monoscopic and stereoscopic photography for research classification of the severity of diabetic retinopathy (DR)...
  10. doi request reprint Suboptimal image focus broadens retinal vessel caliber measurement
    Charles S Chandler
    Department of Ophthalmology and Visual Sciences, Fundus Photograph Reading Center, College of Engineering, Mechanical Engineering General, University of Wisconsin Madison, Madison, WI 53717, USA
    Invest Ophthalmol Vis Sci 52:8558-61. 2011
    ..The authors explored suboptimal image focus as a possible contributing factor to artificially larger vascular caliber measurements...
  11. pmc The relation of atherosclerotic cardiovascular disease to retinopathy in people with diabetes in the Cardiovascular Health Study
    Ronald Klein
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison, WI 53705 2397, USA
    Br J Ophthalmol 86:84-90. 2002
    ..To describe the association of retinopathy with atherosclerosis and atherosclerotic risk factors in people with diabetes...
  12. doi request reprint Imaging of diabetic retinopathy and diabetic macular edema
    Ronald P Danis
    Ophthalmology and Visual Sciences, University of Wisconsin Madison Fundus Photograph Reading Center, 8010 Excelsior Drive, Madison, WI 53717, USA
    Curr Diab Rep 11:236-43. 2011
    ..The classification of diabetic retinopathy severity continues to rely upon fundus photography, although the transition from film to digital photography presents both challenges and advantages...
  13. pmc A severity scale for diabetic macular edema developed from ETDRS data
    Ronald E Gangnon
    Department of Population Health Sciences, University of Wisconsin, Madison, Wisconsin 53711 1068, USA
    Invest Ophthalmol Vis Sci 49:5041-7. 2008
    ..To develop a severity scale for diabetic macular edema (DME) and to assess relationships between severity and duration of DME and visual acuity (VA)...
  14. ncbi request reprint The association of atherosclerosis, vascular risk factors, and retinopathy in adults with diabetes : the atherosclerosis risk in communities study
    Ronald Klein
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Madison, 610 North Walnut Street, Madison, WI 53705 2397, USA
    Ophthalmology 109:1225-34. 2002
    ..The aim of this report is to describe the prevalence of retinopathy and its associations with atherosclerosis and vascular risk factors in people with diabetes...
  15. ncbi request reprint Comparability of two fundus photograph reading centers in grading cytomegalovirus retinitis progression
    Larry D Hubbard
    Department of Ophthalmology and Visual Sciences, The University of Wisconsin Medical School, Madison Wisconsin 53711 1068, USA
    Am J Ophthalmol 137:426-34. 2004
    ..To compare grading of cytomegalovirus retinitis progression by two different fundus photograph reading centers (FPRCs)...
  16. pmc Morphologic assessment for glaucoma in the Multicenter Uveitis Steroid Treatment (MUST) trial
    Sapna S Gangaputra
    Fundus Photograph Reading Center, Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin 53717, USA
    Ocul Immunol Inflamm 19:267-74. 2011
    ..To compare Reading Center (RC) cup-to-disc ratio (CDR) assessment from stereoscopic photographs with clinician estimation in a uveitis clinical trial...
  17. ncbi request reprint Cerebral white matter lesions, retinopathy, and incident clinical stroke
    Tien Yin Wong
    Department of Ophthalmology, University of Wisconsin, Madison, USA
    JAMA 288:67-74. 2002
    ..White matter lesions (WMLs) detected on cerebral imaging scans have been hypothesized to have a microvascular etiology and to precede the development of clinical stroke. However, few clinical data are available to support these hypotheses...
  18. ncbi request reprint Retinal microvascular abnormalities and cognitive impairment in middle-aged persons: the Atherosclerosis Risk in Communities Study
    Tien Yin Wong
    Department of Ophthalmology, University of Wisconsin, Madison, USA
    Stroke 33:1487-92. 2002
    ..Here, we examine the relation of retinal microvascular abnormalities with cognitive function in middle-aged persons free of stroke...
  19. pmc Three-year incidence and cumulative prevalence of retinopathy: the atherosclerosis risk in communities study
    Tien Y Wong
    Centre for Eye Research Australia, University of Melbourne, Victoria, Australia
    Am J Ophthalmol 143:970-6. 2007
    ..To describe the three-year incidence and cumulative prevalence of retinopathy and its risk factors...
  20. ncbi request reprint Apolipoprotein e gene and age-related maculopathy in older individuals: the cardiovascular health study
    Gabriella Tikellis
    Centre for Eye Research Australia, University of Melbourne, Victoria, Australia
    Arch Ophthalmol 125:68-73. 2007
    ..To examine the association between the apolipoprotein E (APOE) gene and age-related maculopathy (ARM) in an older population...
  21. ncbi request reprint Dietary glycemic index and carbohydrate in relation to early age-related macular degeneration
    Chung Jung Chiu
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Am J Clin Nutr 83:880-6. 2006
    ..Several dietary factors have been linked to age-related maculopathy (ARM), the early form of age-related macular degeneration, and there is reason to think that dietary carbohydrate may play a role in the development of ARM...
  22. ncbi request reprint Retinal microvascular abnormalities and MRI-defined subclinical cerebral infarction: the Atherosclerosis Risk in Communities Study
    Lawton S Cooper
    National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA
    Stroke 37:82-6. 2006
    ..Retinal microvascular abnormalities reflect cumulative small vessel damage from elevated blood pressure and may reflect subclinical cerebral microvascular changes. We examined their associations with MRI-defined cerebral infarcts...
  23. ncbi request reprint Progression of diabetic macular edema: correlation with blood retinal barrier permeability, retinal thickness, and retinal vessel diameter
    Birgit Sander
    Department of Ophthalmology, Glostrup Hospital, University of Copenhagen, Denmark
    Invest Ophthalmol Vis Sci 48:3983-7. 2007
    ..To study the progression of diabetic macular edema (DME) in relation to baseline retinal thickness, retinal vascular leakage, and retinal trunk vessel diameters...
  24. ncbi request reprint Clinician versus reading center assessment of cytomegalovirus retinitis lesion size
    David V Weinberg
    Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Ophthalmology 112:559-66. 2005
    ....
  25. ncbi request reprint High dose oral ganciclovir treatment for cytomegalovirus retinitis
    Jacob P Lalezari
    Quest Clinical Research, 2300 Sutter Street, Suite 202 San Francisco, CA 94115, USA
    J Clin Virol 24:67-77. 2002
    ..Median time to progression of CMV retinitis is 12-20 days shorter with oral compared to IV ganciclovir maintenance, likely due to the limited oral bioavailability of ganciclovir...
  26. ncbi request reprint Characteristics of patients with cytomegalovirus retinitis in the era of highly active antiretroviral therapy
    Douglas A Jabs
    Wilmer Eye Institute, 550 North Broadway, Suite 700, Baltimore, Maryland 21205, USA
    Am J Ophthalmol 133:48-61. 2002
    ..To describe the characteristics of patients with AIDS and cytomegalovirus retinitis in the era of highly active antiretroviral therapy (HAART)...
  27. ncbi request reprint Retinal microvascular abnormalities and 10-year cardiovascular mortality: a population-based case-control study
    Tien Yin Wong
    Singapore National Eye Center and National University of Singapore, Singapore, Republic of Singapore
    Ophthalmology 110:933-40. 2003
    ..Retinal microvascular abnormalities reflect persistent arteriolar damage from hypertension and independently predict stroke. We examined their associations with long-term cardiovascular mortality...
  28. pmc The Age-Related Eye Disease Study severity scale for age-related macular degeneration: AREDS Report No. 17
    Matthew D Davis
    AREDS Coordinating Center, EMMES Corp, Rockville, MD 20850 1707, USA
    Arch Ophthalmol 123:1484-98. 2005
    ..To develop a fundus photographic severity scale for age-related macular degeneration (AMD)...
  29. ncbi request reprint Racial differences in the prevalence of hypertensive retinopathy
    Tien Yin Wong
    Department of Ophthalmology, Singapore National Eye Center and National University of Singapore
    Hypertension 41:1086-91. 2003
    ....
  30. ncbi request reprint Is early age-related maculopathy related to cognitive function? The Atherosclerosis Risk in Communities Study
    Tien Yin Wong
    Singapore Eye Research Institute and Department of Ophthalmology, National University of Singapore, Singapore
    Am J Ophthalmol 134:828-35. 2002
    ..We describe the association between cognitive function and ARM in middle-aged persons...
  31. ncbi request reprint Associations between the metabolic syndrome and retinal microvascular signs: the Atherosclerosis Risk In Communities study
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria, Australia
    Invest Ophthalmol Vis Sci 45:2949-54. 2004
    ..To examine the cross-sectional relationship of the metabolic syndrome (hypertension, hyperglycemia, central obesity, and dyslipidemia) and retinal microvascular abnormalities in middle-aged men and women...
  32. ncbi request reprint Reliability of retinal photography in the assessment of retinal microvascular characteristics: the Atherosclerosis Risk in Communities Study
    David J Couper
    Department of Biostatistics, University of North Carolina, Chapel Hill, North Carolina 27514, USA
    Am J Ophthalmol 133:78-88. 2002
    ..Retinal microvascular characteristics, as graded from retinal photography, have been shown to predict stroke. We evaluated the reliability of retinal photographic grading in the Atherosclerosis Risk in Communities Study...
  33. ncbi request reprint Retinal arteriolar narrowing and risk of diabetes mellitus in middle-aged persons
    Tien Yin Wong
    Department of Ophthalmology, National University of Singapore, 10 Kent Ridge Crescent, Singapore 119260
    JAMA 287:2528-33. 2002
    ..Microvascular processes have been hypothesized to play a role in the pathogenesis of type 2 diabetes mellitus, but prospective clinical data regarding this hypothesis are unavailable...
  34. ncbi request reprint Retinal microvascular abnormalities and renal dysfunction: the atherosclerosis risk in communities study
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, 32 Gisborne Street, Victoria 3002, Australia
    J Am Soc Nephrol 15:2469-76. 2004
    ..Retinal microvascular abnormalities are associated with renal dysfunction, suggesting that common systemic microvascular processes may underlie the development of microvascular damage in the eye and kidneys...
  35. ncbi request reprint The prevalence and risk factors of retinal microvascular abnormalities in older persons: The Cardiovascular Health Study
    Tien Yin Wong
    Singapore Eye Research Institute, Singapore, Republic of Singapore
    Ophthalmology 110:658-66. 2003
    ..To describe the prevalence of retinal microvascular characteristics and their associations with atherosclerosis in elderly, nondiabetic persons...
  36. ncbi request reprint Retinal arteriolar narrowing and risk of coronary heart disease in men and women. The Atherosclerosis Risk in Communities Study
    Tien Yin Wong
    Department of Ophthalmology, National University of Singapore, 10 Kent Ridge Crescent, Singapore 119260
    JAMA 287:1153-9. 2002
    ..Microvascular processes have been hypothesized to play a greater role in the development of coronary heart disease (CHD) in women than in men; however, prospective clinical data are limited...
  37. ncbi request reprint Calibration of fundus images using spectral domain optical coherence tomography
    Brandon J Lujan
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
    Ophthalmic Surg Lasers Imaging 39:S15-20. 2008
    ..However, calibrated spectral domain OCT (SD-OCT) could offer a convenient alternative method for the calibration of any fundus image...
  38. ncbi request reprint Relationships between age, blood pressure, and retinal vessel diameters in an older population
    Harry Leung
    Department of Ophthalmology, Centre for Vision Research, and the Westmead Millennium and Save Sight Institutes, The University of Sydney, NSW, Australia
    Invest Ophthalmol Vis Sci 44:2900-4. 2003
    ..To describe the cross-sectional relationships between age, blood pressure (BP), and quantitative measures of retinal vessel diameters in an older Australian population...
  39. ncbi request reprint Intake of zinc and antioxidant micronutrients and early age-related maculopathy lesions
    Martha Savaria Morris
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
    Ophthalmic Epidemiol 14:288-98. 2007
    ..Results of observational and intervention studies have been inconsistent...
  40. ncbi request reprint Cardiovascular risk factors for retinal vein occlusion and arteriolar emboli: the Atherosclerosis Risk in Communities & Cardiovascular Health studies
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia
    Ophthalmology 112:540-7. 2005
    ..To examine the associations of retinal vein occlusion and arteriolar emboli with cardiovascular disease...
  41. ncbi request reprint Estrogen replacement therapy and retinal vascular caliber
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia
    Ophthalmology 112:553-8. 2005
    ..It is unclear if estrogen replacement therapy (ERT) has an effect on the retinal circulation. In the current study, we examine the association of ERT, female reproductive factors, and retinal vascular caliber...
  42. ncbi request reprint Retinal arteriolar narrowing, hypertension, and subsequent risk of diabetes mellitus
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria
    Arch Intern Med 165:1060-5. 2005
    ..Microvascular disease and hypertension have been linked with risk of diabetes mellitus. We examined the association of retinal arteriolar narrowing, a marker of chronic hypertension, with incident diabetes...
  43. ncbi request reprint Retinal arteriolar diameter and risk for hypertension
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, East Melbourne Victoria, Australia
    Ann Intern Med 140:248-55. 2004
    ..Narrowing of the small arterioles has been hypothesized to contribute to the pathogenesis of hypertension, but prospective clinical data are lacking...
  44. pmc Prospective cohort study of retinal vessel diameters and risk of hypertension
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, Victoria 3002, Australia
    BMJ 329:79. 2004
    ..To examine the relation between diameters of the retinal arterioles and 10 year incidence of hypertension...
  45. ncbi request reprint A prospective cohort study of retinal arteriolar narrowing and mortality
    Tien Yin Wong
    Department of Ophthalmology, University of Melbourne, Victoria, Australia
    Am J Epidemiol 159:819-25. 2004
    ....
  46. ncbi request reprint Age-related macular degeneration and risk for stroke
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, Australia
    Ann Intern Med 145:98-106. 2006
    ..Age-related macular degeneration (AMD) affects 7 million persons 40 years of age and older in the United States. Risk factors for the disease are similar to those for stroke...
  47. ncbi request reprint Retinal vessel diameters and their associations with age and blood pressure
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, Australia
    Invest Ophthalmol Vis Sci 44:4644-50. 2003
    ..To describe the cross-sectional relationship between retinal arteriolar and venular diameters with age and blood pressure...
  48. ncbi request reprint Correlation between generalized and focal retinal arteriolar narrowing in an older population
    Ava G Tan
    Centre for Vision Research, Department of Ophthalmology, University of Sydney, Australia
    Clin Experiment Ophthalmol 31:322-5. 2003
    ..These data suggest a moderate correlation between generalized (CRAE) and focal arteriolar narrowing. However, no significant association was found between arteriole-to-venule ratio and focal arteriolar narrowing...
  49. ncbi request reprint Retinal vessel diameters and incident open-angle glaucoma and optic disc changes: the Rotterdam study
    M Kamran Ikram
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Invest Ophthalmol Vis Sci 46:1182-7. 2005
    ..We examined whether baseline retinal vessel diameters were related to incident (i)OAG or incident optic disc changes in a population-based sample...