Xuemei Huang

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. pmc Shape (but not volume) changes in the thalami in Parkinson disease
    Martin J McKeown
    Pacific Parkinson s Research Center, University of British Columbia, Vancouver, Canada
    BMC Neurol 8:8. 2008
  2. ncbi request reprint APOE-[epsilon]2 allele associated with higher prevalence of sporadic Parkinson disease
    Xuemei Huang
    Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7025, USA
    Neurology 62:2198-202. 2004
  3. ncbi request reprint Apolipoprotein E and dementia in Parkinson disease: a meta-analysis
    Xuemei Huang
    Department of Neurology, University of North Carolina School of Medicine, Chapel Hill 27599 7025, USA
    Arch Neurol 63:189-93. 2006
  4. pmc Lower low-density lipoprotein cholesterol levels are associated with Parkinson's disease
    Xuemei Huang
    Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
    Mov Disord 22:377-81. 2007
  5. ncbi request reprint Asymmetrical ventricular enlargement in Parkinson's disease
    Xuemei Huang
    Department of Neurology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599 7025, USA, and University Hospital, Vancouver, British Columbia, Canada
    Mov Disord 22:1657-60. 2007
  6. doi request reprint Low LDL cholesterol and increased risk of Parkinson's disease: prospective results from Honolulu-Asia Aging Study
    Xuemei Huang
    Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 7025, USA
    Mov Disord 23:1013-8. 2008
  7. pmc Imaging nigral pathology and clinical progression in Parkinson's disease
    Guangwei Du
    Department of Neurology, Pennsylvania State University Milton S Hershey Medical Center, Hershey, Pennsylvania 17033 0850, USA
    Mov Disord 27:1636-43. 2012
  8. pmc Early cortical gray matter loss and cognitive correlates in non-demented Parkinson's patients
    Eun Young Lee
    Department of Neurology, Pennsylvania State University Milton S Hershey Medical Center, Hershey, PA 17033, USA
    Parkinsonism Relat Disord 19:1088-93. 2013
  9. pmc Striatal shape in Parkinson's disease
    Nicholas W Sterling
    Department of Neurology, Pennsylvania State University Milton S Hershey Medical Center, Hershey, PA 17033 0850, USA
    Neurobiol Aging 34:2510-6. 2013
  10. pmc Higher iron in the red nucleus marks Parkinson's dyskinesia
    Mechelle M Lewis
    Department of Neurology, Pennsylvania State University Milton S Hershey Medical Center, Hershey, PA 17033 0850, USA
    Neurobiol Aging 34:1497-503. 2013

Research Grants

Detail Information

Publications15

  1. pmc Shape (but not volume) changes in the thalami in Parkinson disease
    Martin J McKeown
    Pacific Parkinson s Research Center, University of British Columbia, Vancouver, Canada
    BMC Neurol 8:8. 2008
    ..Our objective was to determine if changes in the thalami could be non-invasively detected in structural MRI images obtained from subjects with Parkinson disease (PD), compared to age-matched controls...
  2. ncbi request reprint APOE-[epsilon]2 allele associated with higher prevalence of sporadic Parkinson disease
    Xuemei Huang
    Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7025, USA
    Neurology 62:2198-202. 2004
    ..The authors hypothesized that any association between PD and APOE alleles and genotypes would be too small to be detected or precisely estimated by an individual case-controlled study...
  3. ncbi request reprint Apolipoprotein E and dementia in Parkinson disease: a meta-analysis
    Xuemei Huang
    Department of Neurology, University of North Carolina School of Medicine, Chapel Hill 27599 7025, USA
    Arch Neurol 63:189-93. 2006
    ..To understand the relationship of apolipoprotein E (APOE) polymorphism to dementia in Parkinson disease (PD) because the APOE epsilon4 allele is linked to Alzheimer disease...
  4. pmc Lower low-density lipoprotein cholesterol levels are associated with Parkinson's disease
    Xuemei Huang
    Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
    Mov Disord 22:377-81. 2007
    ..Thus, our data provide preliminary evidence that low LDL-C may be associated with higher occurrence of PD, and/or that statin use may lower PD occurrence, either of which finding warrants further investigation...
  5. ncbi request reprint Asymmetrical ventricular enlargement in Parkinson's disease
    Xuemei Huang
    Department of Neurology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599 7025, USA, and University Hospital, Vancouver, British Columbia, Canada
    Mov Disord 22:1657-60. 2007
    ..This is the first report to suggest the presence of asymmetrical ventricular enlargement in PD, findings that may be worthy of further study...
  6. doi request reprint Low LDL cholesterol and increased risk of Parkinson's disease: prospective results from Honolulu-Asia Aging Study
    Xuemei Huang
    Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 7025, USA
    Mov Disord 23:1013-8. 2008
    ..2, 0.9). This prospective study supports the hypothesis that low LDL-C is associated with an increased risk of PD. Although confirmation is required, the underlying mechanisms may be useful in understanding key aspects of PD...
  7. pmc Imaging nigral pathology and clinical progression in Parkinson's disease
    Guangwei Du
    Department of Neurology, Pennsylvania State University Milton S Hershey Medical Center, Hershey, Pennsylvania 17033 0850, USA
    Mov Disord 27:1636-43. 2012
    ..These findings suggest that fractional anisotropy changes may mark early pathological changes in caudal SN, whereas the changes in R2* may more closely track PD's clinical progression after symptom onset...
  8. pmc Early cortical gray matter loss and cognitive correlates in non-demented Parkinson's patients
    Eun Young Lee
    Department of Neurology, Pennsylvania State University Milton S Hershey Medical Center, Hershey, PA 17033, USA
    Parkinsonism Relat Disord 19:1088-93. 2013
    ..This study tested the hypothesis that cognitive changes in non-demented PD may be related to cortical gray matter (GM) loss...
  9. pmc Striatal shape in Parkinson's disease
    Nicholas W Sterling
    Department of Neurology, Pennsylvania State University Milton S Hershey Medical Center, Hershey, PA 17033 0850, USA
    Neurobiol Aging 34:2510-6. 2013
    ..005). This spatial distribution of striatal atrophy is consistent with the known pattern of dopamine depletion in PD and may reflect global consequences of known cellular remodeling phenomena...
  10. pmc Higher iron in the red nucleus marks Parkinson's dyskinesia
    Mechelle M Lewis
    Department of Neurology, Pennsylvania State University Milton S Hershey Medical Center, Hershey, PA 17033 0850, USA
    Neurobiol Aging 34:1497-503. 2013
    ..The association of higher RN iron content with PD-related dyskinesia suggests increased iron content is involved in, or reflects, greater cerebellar compensatory capacity and thus increased likelihood of LID development...
  11. pmc Combined R2* and diffusion tensor imaging changes in the substantia nigra in Parkinson's disease
    Guangwei Du
    Department of Neurology, Pennsylvania State University Milton S Hershey Medical Center, Hershey, Pennsylvania 17033 0850, USA
    Mov Disord 26:1627-32. 2011
    ..Further studies are warranted to evaluate the pathophysiological correlations of these magnetic resonance imaging measurements and their effectiveness in assisting in diagnosing Parkinson's disease and following its progression...
  12. pmc Both coordination and symmetry of arm swing are reduced in Parkinson's disease
    Xuemei Huang
    Department of Neurology, The Pennsylvania State University Milton S Hershey Medical Center, Hershey, PA 17033, USA
    Gait Posture 35:373-7. 2012
    ....
  13. ncbi request reprint The role of the cerebellum in the pathophysiology of Parkinson's disease
    Mechelle M Lewis
    Department of Neurology, Pennsylvania State University Milton S Hershey Medical Center, Hershey PA, USA Department of Pharmacology, Pennsylvania State University Milton S Hershey Medical Center, Hershey PA, USA
    Can J Neurol Sci 40:299-306. 2013
    ..It is clear that the cerebellum participates in compensatory mechanisms associated with the disease and must be considered an essential contributor to the overall pathophysiology of PD...
  14. pmc Arm swing magnitude and asymmetry during gait in the early stages of Parkinson's disease
    Michael D Lewek
    Department of Allied Health Sciences, Division of Physical Therapy, University of North Carolina, Chapel Hill, NC 27599 7135, USA
    Gait Posture 31:256-60. 2010
    ..Such quantitative evaluation of arm swing, especially its asymmetry, may have utility for early and differential diagnosis, and for tracking disease progression in patients with later PD...
  15. pmc Manganese accumulation in the olfactory bulbs and other brain regions of "asymptomatic" welders
    Suman Sen
    Department of Neurology, University of North Carolina at Chapel Hill, North Carolina 27599, USA
    Toxicol Sci 121:160-7. 2011
    ..Further investigations of subclinical Mn exposure are warranted...

Research Grants1

  1. Functional Studies of Subtypes of Parkinson's Diseasee
    Xuemei Huang; Fiscal Year: 2007
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