Research Topics
Species | Xuemei HuangSummaryAffiliation: University of North Carolina Country: USA Publications
Research Grants
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Detail Information
Publications
Shape (but not volume) changes in the thalami in Parkinson diseaseMartin J McKeown
Pacific Parkinson s Research Center, University of British Columbia, Vancouver, Canada
BMC Neurol 8:8. 2008..Our objective was to determine if changes in the thalami could be non-invasively detected in structural MRI images obtained from subjects with Parkinson disease (PD), compared to age-matched controls...
APOE-[epsilon]2 allele associated with higher prevalence of sporadic Parkinson diseaseXuemei Huang
Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7025, USA
Neurology 62:2198-202. 2004..The authors hypothesized that any association between PD and APOE alleles and genotypes would be too small to be detected or precisely estimated by an individual case-controlled study...
Apolipoprotein E and dementia in Parkinson disease: a meta-analysisXuemei Huang
Department of Neurology, University of North Carolina School of Medicine, Chapel Hill 27599 7025, USA
Arch Neurol 63:189-93. 2006..To understand the relationship of apolipoprotein E (APOE) polymorphism to dementia in Parkinson disease (PD) because the APOE epsilon4 allele is linked to Alzheimer disease...
Lower low-density lipoprotein cholesterol levels are associated with Parkinson's diseaseXuemei Huang
Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
Mov Disord 22:377-81. 2007..Thus, our data provide preliminary evidence that low LDL-C may be associated with higher occurrence of PD, and/or that statin use may lower PD occurrence, either of which finding warrants further investigation...
Asymmetrical ventricular enlargement in Parkinson's diseaseXuemei Huang
Department of Neurology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599 7025, USA, and University Hospital, Vancouver, British Columbia, Canada
Mov Disord 22:1657-60. 2007..This is the first report to suggest the presence of asymmetrical ventricular enlargement in PD, findings that may be worthy of further study...
Low LDL cholesterol and increased risk of Parkinson's disease: prospective results from Honolulu-Asia Aging StudyXuemei Huang
Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 7025, USA
Mov Disord 23:1013-8. 2008..2, 0.9). This prospective study supports the hypothesis that low LDL-C is associated with an increased risk of PD. Although confirmation is required, the underlying mechanisms may be useful in understanding key aspects of PD...
Imaging nigral pathology and clinical progression in Parkinson's diseaseGuangwei Du
Department of Neurology, Pennsylvania State University Milton S Hershey Medical Center, Hershey, Pennsylvania 17033 0850, USA
Mov Disord 27:1636-43. 2012..These findings suggest that fractional anisotropy changes may mark early pathological changes in caudal SN, whereas the changes in R2* may more closely track PD's clinical progression after symptom onset...
Combined R2* and diffusion tensor imaging changes in the substantia nigra in Parkinson's diseaseGuangwei Du
Department of Neurology, Pennsylvania State University Milton S Hershey Medical Center, Hershey, Pennsylvania 17033 0850, USA
Mov Disord 26:1627-32. 2011..Further studies are warranted to evaluate the pathophysiological correlations of these magnetic resonance imaging measurements and their effectiveness in assisting in diagnosing Parkinson's disease and following its progression...
Higher iron in the red nucleus marks Parkinson's dyskinesiaMechelle M Lewis
Department of Neurology, Pennsylvania State University Milton S Hershey Medical Center, Hershey, PA 17033 0850, USA
Neurobiol Aging 34:1497-503. 2013..The association of higher RN iron content with PD-related dyskinesia suggests increased iron content is involved in, or reflects, greater cerebellar compensatory capacity and thus increased likelihood of LID development...
Both coordination and symmetry of arm swing are reduced in Parkinson's diseaseXuemei Huang
Department of Neurology, The Pennsylvania State University Milton S Hershey Medical Center, Hershey, PA 17033, USA
Gait Posture 35:373-7. 2012....
Manganese accumulation in the olfactory bulbs and other brain regions of "asymptomatic" weldersSuman Sen
Department of Neurology, University of North Carolina at Chapel Hill, North Carolina 27599, USA
Toxicol Sci 121:160-7. 2011..Further investigations of subclinical Mn exposure are warranted...
Arm swing magnitude and asymmetry during gait in the early stages of Parkinson's diseaseMichael D Lewek
Department of Allied Health Sciences, Division of Physical Therapy, University of North Carolina, Chapel Hill, NC 27599 7135, USA
Gait Posture 31:256-60. 2010..Such quantitative evaluation of arm swing, especially its asymmetry, may have utility for early and differential diagnosis, and for tracking disease progression in patients with later PD...
Research Grants
- Functional Studies of Subtypes of Parkinson's DiseaseeXuemei Huang; Fiscal Year: 2007..abstract_text> ..
