Xiang Run Huang

Summary

Affiliation: University of Miami
Country: USA

Publications

  1. pmc Reflectance decreases before thickness changes in the retinal nerve fiber layer in glaucomatous retinas
    Xiang Run Huang
    Bascom Palmer Eye Institute, University of Miami, Miami, Florida 33136, USA
    Invest Ophthalmol Vis Sci 52:6737-42. 2011
  2. pmc Reflectance speckle of retinal nerve fiber layer reveals axonal activity
    Xiang Run Huang
    Bascom Palmer Eye Institute, University of Miami, Miami, Florida 33136, USA
    Invest Ophthalmol Vis Sci 54:2616-23. 2013
  3. pmc Wavelength-dependent change of retinal nerve fiber layer reflectance in glaucomatous retinas
    Xiang Run Huang
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Invest Ophthalmol Vis Sci 53:5869-76. 2012
  4. pmc Distortion of axonal cytoskeleton: an early sign of glaucomatous damage
    Xiangrun Huang
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 1638 NW Tenth Avenue, Miami, FL 33136, USA
    Invest Ophthalmol Vis Sci 52:2879-88. 2011
  5. pmc Altered F-actin distribution in retinal nerve fiber layer of a rat model of glaucoma
    Xiang Run Huang
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 1638 NW 10th Ave, Miami, FL 33136, USA
    Exp Eye Res 88:1107-14. 2009
  6. ncbi request reprint Microtubule contribution to the reflectance of the retinal nerve fiber layer
    Xiang Run Huang
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
    Invest Ophthalmol Vis Sci 47:5363-7. 2006
  7. ncbi request reprint Quantifying retinal nerve fiber layer thickness in whole-mounted retina
    Xiang Run Huang
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 1638 N W 10th Ave, Miami, FL 33136, USA
    Exp Eye Res 83:1096-101. 2006
  8. ncbi request reprint Microtubules contribute to the birefringence of the retinal nerve fiber layer
    Xiang Run Huang
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
    Invest Ophthalmol Vis Sci 46:4588-93. 2005
  9. ncbi request reprint Variation of peripapillary retinal nerve fiber layer birefringence in normal human subjects
    Xiang Run Huang
    Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Florida 33136, USA
    Invest Ophthalmol Vis Sci 45:3073-80. 2004
  10. ncbi request reprint Linear birefringence of the retinal nerve fiber layer measured in vitro with a multispectral imaging micropolarimeter
    Xiang Run Huang
    University of Miami School of Medicine, Bascom Palmer Eye Institute, Miami, Florida 33136, USA
    J Biomed Opt 7:199-204. 2002

Detail Information

Publications15

  1. pmc Reflectance decreases before thickness changes in the retinal nerve fiber layer in glaucomatous retinas
    Xiang Run Huang
    Bascom Palmer Eye Institute, University of Miami, Miami, Florida 33136, USA
    Invest Ophthalmol Vis Sci 52:6737-42. 2011
    ..RNFL thickness, measured with optical coherence tomography (OCT), is often used in clinical assessment of the damage. In this study the relation between the RNFL reflectance and thickness at early stages of glaucoma was investigated...
  2. pmc Reflectance speckle of retinal nerve fiber layer reveals axonal activity
    Xiang Run Huang
    Bascom Palmer Eye Institute, University of Miami, Miami, Florida 33136, USA
    Invest Ophthalmol Vis Sci 54:2616-23. 2013
    ..This study investigated the retinal nerve fiber layer (RNFL) reflectance speckle and tested the hypothesis that temporal change of RNFL speckle reveals axonal dynamic activity...
  3. pmc Wavelength-dependent change of retinal nerve fiber layer reflectance in glaucomatous retinas
    Xiang Run Huang
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Invest Ophthalmol Vis Sci 53:5869-76. 2012
    ..This study measured the changes in RNFL reflectance spectra that occurred in retinal nerve fiber bundles with different degrees of glaucomatous damage...
  4. pmc Distortion of axonal cytoskeleton: an early sign of glaucomatous damage
    Xiangrun Huang
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 1638 NW Tenth Avenue, Miami, FL 33136, USA
    Invest Ophthalmol Vis Sci 52:2879-88. 2011
    ..Distribution of these components in a whole-mounted retina was examined by confocal microscopy. Fluorescent stain was quantitatively described...
  5. pmc Altered F-actin distribution in retinal nerve fiber layer of a rat model of glaucoma
    Xiang Run Huang
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 1638 NW 10th Ave, Miami, FL 33136, USA
    Exp Eye Res 88:1107-14. 2009
    ..Topographic features of F-actin alteration suggest that F-actin near the ONH is more sensitive to glaucomatous damage. The alteration pattern also suggests an ONH location for the glaucomatous insult in this rat model...
  6. ncbi request reprint Microtubule contribution to the reflectance of the retinal nerve fiber layer
    Xiang Run Huang
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
    Invest Ophthalmol Vis Sci 47:5363-7. 2006
    ..To increase understanding of the anatomic basis for clinical RNFL measurements, this study was conducted to evaluate the MT contribution to RNFL reflectance in rodent retinas by using the MT depolymerizing agent colchicine...
  7. ncbi request reprint Quantifying retinal nerve fiber layer thickness in whole-mounted retina
    Xiang Run Huang
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 1638 N W 10th Ave, Miami, FL 33136, USA
    Exp Eye Res 83:1096-101. 2006
    ..The cross-sectional images provided thickness measurements of the RNFL over the entire field-of-view, not just at the points represented by the conventional histologic section, resulting in a large increase in available data...
  8. ncbi request reprint Microtubules contribute to the birefringence of the retinal nerve fiber layer
    Xiang Run Huang
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
    Invest Ophthalmol Vis Sci 46:4588-93. 2005
    ..MTs are generally assumed to be a major contributor, but this has not been demonstrated. In this study, the MT depolymerizing agent colchicine was used to evaluate the contribution of MTs to RNFL birefringence...
  9. ncbi request reprint Variation of peripapillary retinal nerve fiber layer birefringence in normal human subjects
    Xiang Run Huang
    Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Florida 33136, USA
    Invest Ophthalmol Vis Sci 45:3073-80. 2004
    ..The birefringence (Deltan) depends on the density and composition of axonal organelles. The purpose of this study was to evaluate the distribution of birefringence around the optic nerve head (ONH) in normal subjects...
  10. ncbi request reprint Linear birefringence of the retinal nerve fiber layer measured in vitro with a multispectral imaging micropolarimeter
    Xiang Run Huang
    University of Miami School of Medicine, Bascom Palmer Eye Institute, Miami, Florida 33136, USA
    J Biomed Opt 7:199-204. 2002
    ..These results allow extrapolation of previous visible wavelength measurements to the near-infrared wavelengths used by SLP and validate the use of fixed tissue for RNFL research...
  11. ncbi request reprint Diattenuation and polarization preservation of retinal nerve fiber layer reflectance
    Xiang Run Huang
    Bascom Palmer Eye Institute, University of Miami School of Medicine, PO Box 016880, Miami, Florida 33101 6880, USA
    Appl Opt 42:5737-43. 2003
    ..03. Degree of polarization (DOP) for reflection from the RNFL was also measured. DOP was close to unity at all wavelengths, which indicates that the RNFL is a polarization-preserving reflector...
  12. ncbi request reprint Theoretical model of the polarization properties of the retinal nerve fiber layer in reflection
    Xiang Run Huang
    Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Florida 33136, USA
    Appl Opt 42:5726-36. 2003
    ....
  13. ncbi request reprint Analytical model of scanning laser polarimetry for retinal nerve fiber layer assessment
    Robert W Knighton
    Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Florida, USA
    Invest Ophthalmol Vis Sci 43:383-92. 2002
    ..To develop a quantitative understanding of scanning laser polarimetry (SLP) for retinal nerve fiber layer (RNFL) assessment in glaucoma diagnosis and management...
  14. ncbi request reprint Linear birefringence of the central human cornea
    Robert W Knighton
    Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Florida 33101, USA
    Invest Ophthalmol Vis Sci 43:82-6. 2002
    ..To determine the polarization properties of the central cornea at perpendicular incidence in a normal human population on the assumption that the cornea behaves as a linear retarder...
  15. ncbi request reprint Corneal birefringence mapped by scanning laser polarimetry
    Robert W Knighton
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 1638 NW Tenth Avenue, Miami, FL 33136, USA
    Opt Express 16:13738-51. 2008
    ..Some locations in a few corneas can be uniaxial with the optical axis perpendicular to the surface. Importantly, corneal birefringence varies greatly among people and, within a single cornea, significantly with position...

Research Grants3

  1. Retinal nerve fiber layer in glaucoma: Optical properties and damage mechanisms
    Xiangrun Huang; Fiscal Year: 2010
    ..The ultimate goal of this project is to improve assessment sensitivity for RNFL damage in clinical practice. ..