Vera Huang

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc miRNA goes nuclear
    Vera Huang
    Department of Urology and Helen Diller Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA
    RNA Biol 9:269-73. 2012
  2. pmc Effect of hydroxyurea on the promoter occupancy profiles of tumor suppressor p53 and p73
    Vera Huang
    Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093 0820, USA
    BMC Biol 7:35. 2009
  3. pmc Upregulation of Cyclin B1 by miRNA and its implications in cancer
    Vera Huang
    Department of Urology and Helen Diller Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA 94158, USA
    Nucleic Acids Res 40:1695-707. 2012
  4. pmc Formulation of Small Activating RNA Into Lipidoid Nanoparticles Inhibits Xenograft Prostate Tumor Growth by Inducing p21 Expression
    Robert F Place
    1 Department of Urology and Helen Diller Comprehensive Cancer Center, University of California, San Francisco, California, USA 2 RNA Therapeutics, Inc, San Francisco, California, USA
    Mol Ther Nucleic Acids 1:e15. 2012
  5. doi request reprint Targeted induction of endogenous NKX3-1 by small activating RNA inhibits prostate tumor growth
    Shancheng Ren
    Department of Urology and Helen Diller Comprehensive Cancer Center, University of California San Francisco, San Francisco, California Department of Urology, Shanghai Changhai Hospital, Second Military Medical University, Shanghai, China
    Prostate 73:1591-601. 2013
  6. pmc Induction of NANOG expression by targeting promoter sequence with small activating RNA antagonizes retinoic acid-induced differentiation
    Xiaoling Wang
    Department of Urology, University of California San Francisco, San Francisco, CA 94158, USA
    Biochem J 443:821-8. 2012
  7. pmc Small RNA and transcriptional upregulation
    Victoria Portnoy
    Department of Urology and Helen Diller Comprehensive Cancer Center, University of California San Francisco, USA
    Wiley Interdiscip Rev RNA 2:748-60. 2011

Collaborators

Detail Information

Publications7

  1. pmc miRNA goes nuclear
    Vera Huang
    Department of Urology and Helen Diller Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA
    RNA Biol 9:269-73. 2012
    ..In this point-of-view, we will specifically focus on the nuclear functions of miRNAs and discuss examples of miRNA-directed transcriptional gene regulation identified in recent years...
  2. pmc Effect of hydroxyurea on the promoter occupancy profiles of tumor suppressor p53 and p73
    Vera Huang
    Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093 0820, USA
    BMC Biol 7:35. 2009
    ..The goal of this study was to compare the promoter-binding activity of p53 and p73 at steady state and after genotoxic stress induced by hydroxyurea...
  3. pmc Upregulation of Cyclin B1 by miRNA and its implications in cancer
    Vera Huang
    Department of Urology and Helen Diller Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA 94158, USA
    Nucleic Acids Res 40:1695-707. 2012
    ..Such phenotypes were recapitulated by overexpression of Ccnb1. Our findings reveal an endogenous system by which miRNA functions to activate Ccnb1 expression in mouse cells and manipulate in vivo tumor development/growth...
  4. pmc Formulation of Small Activating RNA Into Lipidoid Nanoparticles Inhibits Xenograft Prostate Tumor Growth by Inducing p21 Expression
    Robert F Place
    1 Department of Urology and Helen Diller Comprehensive Cancer Center, University of California, San Francisco, California, USA 2 RNA Therapeutics, Inc, San Francisco, California, USA
    Mol Ther Nucleic Acids 1:e15. 2012
    ..Our results provide proof-of-principle that RNAa in conjunction with lipidioids may represent a novel approach for stimulating gene expression in vivo to treat disease...
  5. doi request reprint Targeted induction of endogenous NKX3-1 by small activating RNA inhibits prostate tumor growth
    Shancheng Ren
    Department of Urology and Helen Diller Comprehensive Cancer Center, University of California San Francisco, San Francisco, California Department of Urology, Shanghai Changhai Hospital, Second Military Medical University, Shanghai, China
    Prostate 73:1591-601. 2013
    ..We used saRNA as a molecular tool to examine NKX3-1's role as a tumor suppressor and tested in vitro and in vivo antitumor effects of NKX3-1 induction by saRNA...
  6. pmc Induction of NANOG expression by targeting promoter sequence with small activating RNA antagonizes retinoic acid-induced differentiation
    Xiaoling Wang
    Department of Urology, University of California San Francisco, San Francisco, CA 94158, USA
    Biochem J 443:821-8. 2012
    ..Ectopic overexpression of NANOG via lentiviral transduction further recapitulates saRNA results, providing proof-of-concept that RNAa may be utilized to activate development-related genes and manipulate cell fate...
  7. pmc Small RNA and transcriptional upregulation
    Victoria Portnoy
    Department of Urology and Helen Diller Comprehensive Cancer Center, University of California San Francisco, USA
    Wiley Interdiscip Rev RNA 2:748-60. 2011
    ..WIREs RNA 2011 2 748-760 DOI: 10.1002/wrna.90 For further resources related to this article, please visit the WIREs website...