Research Topics
| Li Shan HuangSummaryAffiliation: University of Rochester Country: USA Publications
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Detail Information
Publications
Using measurement error models to assess effects of prenatal and postnatal methylmercury exposure in the Seychelles Child Development StudyLi Shan Huang
Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 630, Rochester, NY 14642, USA
Environ Res 93:115-22. 2003..Our reanalysis indicated that adjustment for measurement errors in explanatory variables had no appreciable effect on the original results...- Exploring nonlinear association between prenatal methylmercury exposure from fish consumption and child development: evaluation of the Seychelles Child Development Study nine-year data using semiparametric additive modelsLi Shan Huang
Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Environ Res 97:100-8. 2005..We conclude that this reanalysis supports the primary linear analysis, showing little evidence for a prenatal adverse effect... 
Is susceptibility to prenatal methylmercury exposure from fish consumption non-homogeneous? Tree-structured analysis for the Seychelles Child Development StudyLi Shan Huang
Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Neurotoxicology 28:1237-44. 2007..The regression tree results support previous analyses of outcomes in this cohort. However, this analysis raises the intriguing possibility that an effect may be non-homogeneous among children with different backgrounds and IQ levels...- Fish consumption and prenatal methylmercury exposure: cognitive and behavioral outcomes in the main cohort at 17 years from the Seychelles child development studyPhilip W Davidson
Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Neurotoxicology 32:711-7. 2011..For some endpoints we found performance improved with increasing prenatal exposure to MeHg. Follow up studies indicate this association is related to the beneficial nutrients present in fish... - Methylmercury and neurodevelopment: longitudinal analysis of the Seychelles child development cohortPhilip W Davidson
The Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, New York, 14642, USA
Neurotoxicol Teratol 28:529-35. 2006..These findings suggest that the associations observed between MeHg and developmental outcomes may vary with developmental stage... - Pulmonary function, diffusing capacity, and inflammation in healthy and asthmatic subjects exposed to ultrafine particlesAnthony P Pietropaoli
Department of Medicine, University of Rochester School of Medicine and Dentistry, New York 14642, USA
Inhal Toxicol 16:59-72. 2004..Additional studies are required to confirm these findings in normal subjects, compare them with additional susceptible patient populations, and determine their pathophysiologic mechanisms... - Varying coefficient function models to explore interactions between maternal nutritional status and prenatal methylmercury toxicity in the Seychelles Child Development Nutrition StudyMiranda L Lynch
Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Environ Res 111:75-80. 2011..The results encourage more emphasis on a holistic view of the risks and benefits of fish consumption as it relates to infant development... 
Inhalation of ultrafine particles alters blood leukocyte expression of adhesion molecules in humansMark W Frampton
Department of Medicine, University of Rochester School of Medicine, Rochester, New York 14642 8692, USA
Environ Health Perspect 114:51-8. 2006..Inhalation of elemental carbon UFPs alters peripheral blood leukocyte distribution and expression of adhesion molecules, in a pattern consistent with increased retention of leukocytes in the pulmonary vascular bed...- Association between prenatal exposure to methylmercury and visuospatial ability at 10.7 years in the seychelles child development studyPhilip W Davidson
University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Neurotoxicology 29:453-9. 2008..04), but not when the single outlier was removed (p=0.07). In a population whose exposure to MeHg is from fish consumption, we continue to find no consistent adverse association between MeHg and visual motor coordination... - Urinary incontinence in nulliparous women and their parous sistersGunhilde M Buchsbaum
Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York, USA
Obstet Gynecol 106:1253-8. 2005..To investigate the role of vaginal delivery and familial factors in the development of urinary incontinence by comparing the prevalence of this condition in nulliparous women and their parous sisters... - Fish consumption, mercury exposure, and their associations with scholastic achievement in the Seychelles Child Development StudyPhilip W Davidson
University of Rochester, School of Medicine and Dentistry, Department of Pediatrics, Rochester, NY 14642, USA
Neurotoxicology 31:439-47. 2010..The adverse association of educational measures with postnatal exposure in males is intriguing, but will need to be confirmed by further studies examining factors that influence scholastic achievement... - Neurodevelopmental effects of maternal nutritional status and exposure to methylmercury from eating fish during pregnancyPhilip W Davidson
University of Rochester School of Medicine and Dentistry, Box 671, URMC, 601 Elmwood Avenue, Rochester, NY 14642, USA
Neurotoxicology 29:767-75. 2008..These findings suggest a possible confounding role of maternal nutrition in studies examining associations between prenatal MeHg exposures and developmental outcomes in children... - Vascular effects of ultrafine particles in persons with type 2 diabetesJudith C Stewart
Department of Medicine, University of Rochester Medical Center, Rochester, New York 14642, USA
Environ Health Perspect 118:1692-8. 2010..Diabetes confers an increased risk for cardiovascular effects of airborne particles... - Effect of inhaled carbon ultrafine particles on reactive hyperemia in healthy human subjectsAlpa P Shah
Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA
Environ Health Perspect 116:375-80. 2008..Ultrafine particles (UFP) may contribute to the cardiovascular effects of exposure to particulate air pollution, partly because of their relatively efficient alveolar deposition and potential to enter the pulmonary vascular space... - ECG parameters and exposure to carbon ultrafine particles in young healthy subjectsWojciech Zareba
Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
Inhal Toxicol 21:223-33. 2009..However, trends are observed indicating that some subjects might be susceptible to air pollution, with a response involving autonomic modulation of the heart and repolarization of the ventricular myocardium... - Smoking in dialysis patients: a systematic review and meta-analysis of mortality and cardiovascular morbidityScott E Liebman
Division of Nephrology, University of Rochester Medical Center, NY, USA
Am J Kidney Dis 58:257-65. 2011..Cigarette smoking is associated with increased cardiovascular morbidity and mortality in the general population, but the effect of smoking on these outcomes in the dialysis population is less well studied... - Efficacy of soaking in 70% isopropyl alcohol on aerobic bacterial decontamination of surgical instruments and gloves for serial mouse laparotomiesJessica N Keen
Department of Comparative Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
J Am Assoc Lab Anim Sci 49:832-7. 2010..In this study, we observed that the modified aseptic technique using 70% isopropyl alcohol soaks pre- vented aerobic bacterial contamination of instruments and gloves for as many as 5 mice... - Prenatal methylmercury exposure from ocean fish consumption in the Seychelles child development studyGary J Myers
Department of Neurology, National Institute for Child Health and Development, National Institutes of Health, Department of Health and Human Services, Bethesda, USA
Lancet 361:1686-92. 2003..The most common form of prenatal exposure is maternal fish consumption, but whether such exposure harms the fetus is unknown. We aimed to identify adverse neurodevelopmental effects in a fish-consuming population... - The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsivenessDavid C Foster
Department of Obstetrics and Gynecology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
Obstet Gynecol 113:825-32. 2009..We report upon the reliability, validity, and responsiveness to change of the Tampon Test as an outcome measure for vulvodynia clinical trials... - Comparing inhaled ultrafine versus fine zinc oxide particles in healthy adults: a human inhalation studyWilliam S Beckett
Department of Envrionmental Medicine, University of Rochester School of Medicine and Dentistry, University of Rochester Medical Center, 601 Elmwood Avenue, Box EHSC, Rochester, New York 14642, USA
Am J Respir Crit Care Med 171:1129-35. 2005..Ultrafine particles (< 0.1 microm diameter) are believed to be more potent than an equal mass of inhaled accumulation mode particles (0.1-1.0 microm diameter)... 
Oral desipramine and topical lidocaine for vulvodynia: a randomized controlled trialDavid C Foster
Departments of Obstetrics and Gynecology, Biostatistics, Anesthesiology and Neurology, and Psychiatry, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
Obstet Gynecol 116:583-93. 2010..To estimate the efficacy of common treatments for vulvodynia: topical lidocaine monotherapy, oral desipramine monotherapy, and lidocaine-desipramine combined therapy...- Pelvic organ prolapse in nulliparous women and their parous sistersGunhilde M Buchsbaum
Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York 14642, USA
Obstet Gynecol 108:1388-93. 2006..To investigate the role of vaginal delivery and familial factors in the development of pelvic organ prolapse by comparing the prevalence of this condition in nulliparous women and their parous sisters...