Research Topics
Species | C L HuangSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
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Detail Information
Publications
Binding of the G protein betagamma subunit to multiple regions of G protein-gated inward-rectifying K+ channelsC L Huang
Department of Physiology, The University of California at San Francisco, 94143 0724, USA
FEBS Lett 405:291-8. 1997..These results are consistent with the idea that the N- and C-terminal domains of the cardiac G protein-gated K+ channel subunits may interact with each other to form higher affinity binding site(s) for G betagamma...
Recent advances on renal inward rectifier K+ channelsC L Huang
Department of Medicine, University of Texas Southwestern Medical Center, Dallas 75235 8856, USA
Curr Opin Nephrol Hypertens 7:503-8. 1998..This review discusses recent advances in inward rectifier K+ channels with a special emphasis on the renal channels...
Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by GbetagammaC L Huang
Department of Medicine, University of Texas Southwestern Medical Center at Dallas, 75235, USA
Nature 391:803-6. 1998..Finally, coexpression of Gbetagamma with GIRK channels slows the inhibition of K+ currents by PIP2 antibodies by more than 10-fold. Thus Gbetagamma activates GIRK channels by stabilizing interactions between PIP2 and the K+ channel...
Regulation of ROMK trafficking and channel activityC L Huang
Division of Nephrology, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390 8856, USA
Curr Opin Nephrol Hypertens 10:693-8. 2001..Relevant publications on the related inward rectifier potassium channels will also be discussed...
A new function for CD38/ADP-ribosyl cyclase in nuclear Ca2+ homeostasisO A Adebanjo
Department of Medicine, Medical College of Pennsylvania School of Medicine and Veterans Affairs Medical Center, Philadelphia, Pennsylvania 19104, USA
Nat Cell Biol 1:409-14. 1999..The latter activates ryanodine receptors of the inner nuclear membrane to trigger nucleoplasmic Ca2+ release...
tie-1 protein tyrosine kinase: a novel independent prognostic marker for gastric cancerW C Lin
Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan, Republic of China
Clin Cancer Res 5:1745-51. 1999..Our results illustrate the utility of tyrosine kinase gene family profiling in human gastric cancers and show that tie-1 tyrosine kinase may serve as a novel independent prognostic marker for gastric adenocarcinoma patients...
Calcium waves induced by hypertonic solutions in intact frog skeletal muscle fibresS Chawla
Physiological Laboratory, Department of Anatomy, University of Cambridge, Cambridge CB2 3EG, UK
J Physiol 536:351-9. 2001....
Effects of premature stimulation on HERG K(+) channelsY Lu
Section of Cardiovascular Biology, Department of Biochemistry, University of Cambridge, Cambridge CB2 1QW, UK
J Physiol 537:843-51. 2001..6. These properties of HERG K(+) channels may help to suppress arrhythmias initiated by early afterdepolarizations and premature beats in the ventricles, Purkinje fibres or atria...
