Chi yuan Hsu

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Acute kidney injury in the elderly: predisposition to chronic kidney disease and vice versa
    Steven G Coca
    Section of Nephrology, Yale University School of Medicine, New Haven, CT, USA
    Nephron Clin Pract 119:c19-24. 2011
  2. pmc FGF-23 and PTH levels in patients with acute kidney injury: A cross-sectional case series study
    Maryann Zhang
    Division of Nephrology, Department of Medicine, University of California, San Francisco, CA, USA
    Ann Intensive Care 1:21. 2011
  3. pmc The risk of acute renal failure in patients with chronic kidney disease
    C Y Hsu
    Department of Medicine, University of California, San Francisco, California 94143 0532, USA
    Kidney Int 74:101-7. 2008
  4. ncbi request reprint Racial differences in the progression from chronic renal insufficiency to end-stage renal disease in the United States
    Chi yuan Hsu
    Division of Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, California 94143, USA
    J Am Soc Nephrol 14:2902-7. 2003
  5. ncbi request reprint The incidence of end-stage renal disease is increasing faster than the prevalence of chronic renal insufficiency
    Chi yuan Hsu
    University of California, San Francisco, San Francisco, California 94143 0532, USA
    Ann Intern Med 141:95-101. 2004
  6. pmc Nonrecovery of kidney function and death after acute on chronic renal failure
    Chi yuan Hsu
    Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 0532, USA
    Clin J Am Soc Nephrol 4:891-8. 2009
  7. ncbi request reprint Elevated blood pressure and risk of end-stage renal disease in subjects without baseline kidney disease
    Chi yuan Hsu
    Department of Medicine, University of California, San Francisco, CA 94143, USA
    Arch Intern Med 165:923-8. 2005
  8. ncbi request reprint Body mass index and risk for end-stage renal disease
    Chi yuan Hsu
    Division of Nephrology, University of California, San Francisco, San Francisco, California 94143 0532, USA
    Ann Intern Med 144:21-8. 2006
  9. pmc Risk factors for end-stage renal disease: 25-year follow-up
    Chi yuan Hsu
    Department of Medicine, University of California, San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143 0532, USA
    Arch Intern Med 169:342-50. 2009
  10. ncbi request reprint Linking the population epidemiology of acute renal failure, chronic kidney disease and end-stage renal disease
    Chi yuan Hsu
    Division of Nephrology, University of California, San Francisco, California 94143 0532, USA
    Curr Opin Nephrol Hypertens 16:221-6. 2007

Detail Information

Publications83

  1. pmc Acute kidney injury in the elderly: predisposition to chronic kidney disease and vice versa
    Steven G Coca
    Section of Nephrology, Yale University School of Medicine, New Haven, CT, USA
    Nephron Clin Pract 119:c19-24. 2011
    ..Since AKI heightens the risk for the development and acceleration of CKD, this implies significant public health concerns with regard to the absolute number of elderly persons developing incident CKD...
  2. pmc FGF-23 and PTH levels in patients with acute kidney injury: A cross-sectional case series study
    Maryann Zhang
    Division of Nephrology, Department of Medicine, University of California, San Francisco, CA, USA
    Ann Intensive Care 1:21. 2011
    ..abstract:..
  3. pmc The risk of acute renal failure in patients with chronic kidney disease
    C Y Hsu
    Department of Medicine, University of California, San Francisco, California 94143 0532, USA
    Kidney Int 74:101-7. 2008
    ..Several common risk factors for chronic kidney disease also increase the peril of nosocomial acute kidney failure...
  4. ncbi request reprint Racial differences in the progression from chronic renal insufficiency to end-stage renal disease in the United States
    Chi yuan Hsu
    Division of Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, California 94143, USA
    J Am Soc Nephrol 14:2902-7. 2003
    ..The key to understanding black-white differences in ESRD incidence lies in understanding the extreme differences in their progression from CRI to ESRD...
  5. ncbi request reprint The incidence of end-stage renal disease is increasing faster than the prevalence of chronic renal insufficiency
    Chi yuan Hsu
    University of California, San Francisco, San Francisco, California 94143 0532, USA
    Ann Intern Med 141:95-101. 2004
    ..The steady increase in end-stage renal disease (ESRD) incidence is a worldwide public health crisis...
  6. pmc Nonrecovery of kidney function and death after acute on chronic renal failure
    Chi yuan Hsu
    Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 0532, USA
    Clin J Am Soc Nephrol 4:891-8. 2009
    ..Relatively little is known about clinical outcomes, especially long-term outcomes, among patients who have chronic kidney disease (CKD) and experience superimposed acute renal failure (ARF; acute on chronic renal failure)...
  7. ncbi request reprint Elevated blood pressure and risk of end-stage renal disease in subjects without baseline kidney disease
    Chi yuan Hsu
    Department of Medicine, University of California, San Francisco, CA 94143, USA
    Arch Intern Med 165:923-8. 2005
    ..Previous cohort studies of the relationship between blood pressure and ESRD did not uniformly screen out baseline kidney disease...
  8. ncbi request reprint Body mass index and risk for end-stage renal disease
    Chi yuan Hsu
    Division of Nephrology, University of California, San Francisco, San Francisco, California 94143 0532, USA
    Ann Intern Med 144:21-8. 2006
    ..Although interest in the relationship between obesity and kidney disease is increasing, few epidemiologic studies have examined whether excess weight is an independent risk factor for end-stage renal disease (ESRD)...
  9. pmc Risk factors for end-stage renal disease: 25-year follow-up
    Chi yuan Hsu
    Department of Medicine, University of California, San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143 0532, USA
    Arch Intern Med 169:342-50. 2009
    ..Few cohort studies have focused on risk factors for end-stage renal disease (ESRD). This investigation evaluated the prognostic value of several potential novel risk factors for ESRD after considering established risk factors...
  10. ncbi request reprint Linking the population epidemiology of acute renal failure, chronic kidney disease and end-stage renal disease
    Chi yuan Hsu
    Division of Nephrology, University of California, San Francisco, California 94143 0532, USA
    Curr Opin Nephrol Hypertens 16:221-6. 2007
  11. pmc Community-based incidence of acute renal failure
    C Y Hsu
    Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 0532, USA
    Kidney Int 72:208-12. 2007
    ..Both dialysis-requiring and non-dialysis requiring ARFs are becoming more common. Our data underscore the public health importance of ARF...
  12. ncbi request reprint Exploring secular trends in the likelihood of receiving treatment for end-stage renal disease
    Chi yuan Hsu
    Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 0532, USA
    Clin J Am Soc Nephrol 2:81-8. 2007
    ..This trend was not accounted for by increasing prevalence of baseline CKD or risk factors for renal failure. These findings should spur further research into other forces that drive the rise in treated ESRD...
  13. pmc Measured GFR does not outperform estimated GFR in predicting CKD-related complications
    Chi yuan Hsu
    Division of Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 0532, USA
    J Am Soc Nephrol 22:1931-7. 2011
    ..These results raise questions regarding the conventional view that iGFR is the "gold standard" measure of kidney function...
  14. ncbi request reprint Iron status and hemoglobin level in chronic renal insufficiency
    Chi yuan Hsu
    Division of Nephrology, University of California, San Francisco, 94143, USA
    J Am Soc Nephrol 13:2783-6. 2002
    ..It is concluded that ferritin and TSAT targets derived from ESRD studies may not be applicable to subjects with CRI. Further studies are needed to guide optimization of iron status and hemoglobin level in the much larger CRI population...
  15. ncbi request reprint Elevations of serum phosphorus and potassium in mild to moderate chronic renal insufficiency
    Chi yuan Hsu
    Division of Nephrology, University of California at San Francisco, San Francisco, CA 94143, USA
    Nephrol Dial Transplant 17:1419-25. 2002
    ..However, the extent of these changes and their magnitude in relation to renal function is not well defined, especially among individuals with mild to moderate chronic renal insufficiency (CRI)...
  16. ncbi request reprint Epidemiology of anemia associated with chronic renal insufficiency among adults in the United States: results from the Third National Health and Nutrition Examination Survey
    Chi yuan Hsu
    Division of Nephrology, Division of Biostatistics, University of California, San Francisco, San Francisco, California 94143 0532, USA
    J Am Soc Nephrol 13:504-10. 2002
    ..The public health burden of anemia associated with CRI may be substantial, given the large number of people with CRI; and that even a modest reduction in renal function is associated with decreased hemoglobin level...
  17. ncbi request reprint Methodological issues in studying the epidemiology of mild to moderate chronic renal insufficiency
    Chi yuan Hsu
    Division of Nephrology, University of California, San Francisco, San Francisco, California 94143 0532, USA
    Kidney Int 61:1567-76. 2002
    ..As we enter an era of more intensive study of mild to moderate CRI, recognition of these potential pitfalls should guide researchers toward improving the quality of epidemiological research in this field...
  18. ncbi request reprint Blood pressure and angiotensin converting enzyme inhibitor use in hypertensive patients with chronic renal insufficiency
    C Y Hsu
    Division of Nephrology, University of California, San Francisco 94143 0532, USA
    Am J Hypertens 14:1219-25. 2001
    ..Hypertension treatment is important in managing chronic renal insufficiency (CRI). Little is known, however, about the blood pressure (BP) control achieved or the pattern of antihypertensive drug prescription among CRI patients...
  19. ncbi request reprint Bone mineral density is not diminished by mild to moderate chronic renal insufficiency
    Chi yuan Hsu
    Division of Nephrology, Prevention Science Group, University of California, San Francisco, San Francisco, California 94143 0532, USA
    Kidney Int 61:1814-20. 2002
    ..Persons with mild to moderate chronic renal insufficiency (CRI) may have reduced bone mineral density (BMD) as a result of abnormalities in acid-base and vitamin D-parathyroid hormone homeostasis...
  20. ncbi request reprint Does non-malignant hypertension cause renal insufficiency? Evidence-based perspective
    Chi yuan Hsu
    Division of Nephrology, University of California, San Francisco, California, USA
    Curr Opin Nephrol Hypertens 11:267-72. 2002
    ..Failure to evaluate the possibility that pre-existing renal disease could explain any observed association between elevated blood pressure and subsequent loss of renal function is an important limitation of published studies...
  21. ncbi request reprint Does treatment of non-malignant hypertension reduce the incidence of renal dysfunction? A meta-analysis of 10 randomised, controlled trials
    C Y Hsu
    Division of Nephrology, University of California, San Francisco, CA 94143 0532, USA
    J Hum Hypertens 15:99-106. 2001
    ..This meta-analysis was conducted to determine whether antihypertensive drug therapy reduces the incidence of renal dysfunction in patients with non-malignant hypertension...
  22. ncbi request reprint Epidemiology of anemia associated with chronic renal insufficiency
    Chi yuan Hsu
    Division of Nephrology, University of California, San Francisco, California, USA
    Curr Opin Nephrol Hypertens 11:337-41. 2002
    ..Further studies are needed to define the clinical implications of this common condition and to determine the most appropriate therapeutic response...
  23. ncbi request reprint Diabetes, hemoglobin A(1c), cholesterol, and the risk of moderate chronic renal insufficiency in an ambulatory population
    C Y Hsu
    Division of Nephrology, University of California, San Francisco, CA 94143 0532, USA
    Am J Kidney Dis 36:272-81. 2000
    ..Modification of these risk factors may decrease the incidence of moderate chronic renal insufficiency...
  24. pmc Dialysis-requiring acute renal failure increases the risk of progressive chronic kidney disease
    Lowell J Lo
    Department of Medicine, University of California, San Francisco, 94143 0532, USA
    Kidney Int 76:893-9. 2009
    ....
  25. doi request reprint Association of sleep-related problems with CKD in the United States, 2005-2008
    Laura Plantinga
    Department of Medicine, San Francisco General Hospital and University of California, USA
    Am J Kidney Dis 58:554-64. 2011
    ..We examined the prevalence of a variety of sleep-related problems in persons with and without CKD...
  26. pmc Chronic kidney disease awareness among individuals with clinical markers of kidney dysfunction
    Delphine S Tuot
    521 Parnassus Avenue, Clinical Science Building C 443, Box 0532, Division of Nephrology, University of California, San Francisco, San Francisco, CA 94143, USA
    Clin J Am Soc Nephrol 6:1838-44. 2011
    ..Whether clinical cues prompt recognition of CKD is unknown. We examined whether markers of kidney disease that should trigger CKD recognition among providers are associated with higher individual CKD awareness...
  27. pmc Association of CKD with disability in the United States
    Laura C Plantinga
    Department of Medicine, San Francisco General Hospital, University of California, 94110, USA
    Am J Kidney Dis 57:212-27. 2011
    ..Little is known about disability in early-stage chronic kidney disease (CKD)...
  28. pmc Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease
    Tamara Isakova
    Division of Nephrology and Hypertension, Department of Medicine, University of Miami, Miller School of Medicine, 1120 NW 14th St, Miami, FL 33136, USA
    JAMA 305:2432-9. 2011
    ....
  29. pmc Being overweight modifies the association between cardiovascular risk factors and microalbuminuria in adolescents
    Stephanie Nguyen
    Department of Pediatrics, University of California, San Francisco, California, USA
    Pediatrics 121:37-45. 2008
    ..The goal was to determine the association between cardiovascular risk factors and microalbuminuria in a nationally representative sample of adolescents and to determine whether being overweight modifies this association...
  30. pmc Urine neutrophil gelatinase-associated lipocalin levels do not improve risk prediction of progressive chronic kidney disease
    Kathleen D Liu
    Division of Nephrology, University of California, San Francisco, San Francisco, California, USA
    Kidney Int 83:909-14. 2013
    ..Thus, while urine NGAL was an independent risk factor of progression among patients with established CKD of diverse etiology, it did not substantially improve prediction of outcome events...
  31. ncbi request reprint The conundrum of increased burden of end-stage renal disease in Asians
    Yoshio N Hall
    Department of Medicine, University of California San Francisco, USA
    Kidney Int 68:2310-6. 2005
    ..Few cohort studies have examined the risk of end-stage renal disease (ESRD) among Asians compared with whites and blacks...
  32. pmc Does chronic kidney disease modify the association between body mass index and cardiovascular disease risk factors
    Nisha Bansal
    Department of Medicine, University of California, San Francisco, California 94143, USA
    J Nephrol 25:317-24. 2012
    ..To test this hypothesis, we determined the relationship between BMI and CVD risk factors in patients with and without CKD...
  33. pmc Incident atrial fibrillation and risk of end-stage renal disease in adults with chronic kidney disease
    Nisha Bansal
    Division of Nephrology, Department of Medicine, University of California, San Francisco, 521 Parnassus Ave, Box 0532, San Francisco, CA 94143, USA
    Circulation 127:569-74. 2013
    ..In this study, we determined the association between incident AF and risk of end-stage renal disease (ESRD) among adults with CKD...
  34. pmc Comparison of associations of urine protein-creatinine ratio versus albumin-creatinine ratio with complications of CKD: a cross-sectional analysis
    Herrick Fisher
    University of California, San Francisco, CA
    Am J Kidney Dis 62:1102-8. 2013
    ..We studied the association of ACR and PCR with common complications of CKD...
  35. ncbi request reprint Health-related quality of life and estimates of utility in chronic kidney disease
    Irina Gorodetskaya
    Division of Nephrology, Department of Medicine, University of California San Francisco, San Francisco, CA 94118 1211, USA
    Kidney Int 68:2801-8. 2005
    ..Health-related quality of life and estimates of utility have been carefully evaluated in persons with end-stage renal disease. Fewer studies have examined these parameters in persons with chronic kidney disease (CKD)...
  36. pmc A longitudinal study of left ventricular function and structure from CKD to ESRD: the CRIC study
    Nisha Bansal
    Division of Nephrology, University of California, San Francisco, 521 Parnassus Avenue, Box 0532, San Francisco, CA 94143, USA
    Clin J Am Soc Nephrol 8:355-62. 2013
    ..A better understanding of changes in left ventricular mass and ejection fraction during the transition from CKD to ESRD may provide important insights to opportunities to improve cardiac outcomes...
  37. pmc Is awareness of chronic kidney disease associated with evidence-based guideline-concordant outcomes?
    Delphine S Tuot
    Division of Nephrology, University of California, San Francisco, USA
    Am J Nephrol 35:191-7. 2012
    ..Efforts are underway to increase recognition of CKD among patients, assuming that such an increase will lead to better outcomes through greater adherence to proven therapies. Few studies have tested this assumption...
  38. pmc Nonsteroidal anti-inflammatory drug use among persons with chronic kidney disease in the United States
    Laura Plantinga
    Department of Medicine, University of California, San Francisco, California, USA
    Ann Fam Med 9:423-30. 2011
    ..Because avoidance of nonsteroidal anti-inflammatory drugs (NSAIDs) is recommended for most individuals with chronic kidney disease (CKD), we sought to characterize patterns of NSAID use among persons with CKD in the United States...
  39. pmc Relationship of estimated GFR and coronary artery calcification in the CRIC (Chronic Renal Insufficiency Cohort) Study
    Matthew J Budoff
    Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA, USA
    Am J Kidney Dis 58:519-26. 2011
    ..Although individuals with chronic kidney disease (CKD) are at markedly increased mortality risk, the incidence, prevalence, and prognosis of CAC in CKD are not well understood...
  40. pmc Healthy behaviors, risk factor control and awareness of chronic kidney disease
    Delphine S Tuot
    Department of Medicine, University of California at San Francisco, San Francisco, CA 94110, USA
    Am J Nephrol 37:135-43. 2013
    ..To encourage adoption of healthy behaviors, a better understanding of barriers to participation in CKD-healthy behaviors is needed...
  41. ncbi request reprint The severity of secondary hyperparathyroidism in chronic renal insufficiency is GFR-dependent, race-dependent, and associated with cardiovascular disease
    Ian H De Boer
    Division of Nephrology, Department of Medicine, University of California San Francisco, 94118, USA
    J Am Soc Nephrol 13:2762-9. 2002
    ..0; 95% CI, 1.3 to 2.9 per unit natural log PTH) and not associated with other co-morbid conditions. These factors should be considered when screening and managing SHPT in CRI...
  42. ncbi request reprint Factors associated with future amputation among patients undergoing hemodialysis: results from the Dialysis Morbidity and Mortality Study Waves 3 and 4
    ANN M O'HARE
    Department of Medicine, Nephrology Division, University of California, San Francisco, CA 94143 0532, USA
    Am J Kidney Dis 41:162-70. 2003
    ..Amputation is more common in hemodialysis patients than in the general population, but risk factors for amputation in this population have not been studied extensively...
  43. pmc Subclinical cardiac abnormalities and kidney function decline: the multi-ethnic study of atherosclerosis
    Meyeon Park
    Division of Nephrology, Department of Medicine, University of California, San Francisco, CA 94121, USA
    Clin J Am Soc Nephrol 7:1137-44. 2012
    ..Whether subclinical abnormalities of cardiac structure are associated with faster kidney function decline is not known. The association between cardiac concentricity and kidney function decline was evaluated...
  44. pmc Vulnerable populations and the association between periodontal and chronic kidney disease
    Vanessa Grubbs
    Division of Nephrology, University of California San Francisco San Francisco General Hospital Renal Center, Box 1341, 1001 Potrero Avenue, Building 100, Room 342, San Francisco, CA 94110, USA
    Clin J Am Soc Nephrol 6:711-7. 2011
    ..Recent studies suggest an overall association between chronic kidney disease (CKD) and periodontal disease, but it is unknown whether this association is similar across various subpopulations...
  45. pmc Association between kidney function and telomere length: the heart and soul study
    Nisha Bansal
    Department of Medicine, University of California, San Francisco, USA
    Am J Nephrol 36:405-11. 2012
    ..Telomere attrition is a novel risk factor for cardiovascular disease. Studies of telomere length in relation to kidney function are limited. We explored the association of kidney function with telomere length and telomere shortening...
  46. pmc Associations between kidney function and subclinical cardiac abnormalities in CKD
    Meyeon Park
    Division of Nephrology, University of California, 521 Parnassus Avenue, San Francisco, CA 94143, USA
    J Am Soc Nephrol 23:1725-34. 2012
    ..We did not detect significant associations between kidney function and systolic or diastolic function after adjusting for potential confounding variables...
  47. pmc Relationship of urine dopamine with phosphorus homeostasis in humans: the heart and soul study
    Nisha Bansal
    Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA
    Am J Nephrol 35:483-90. 2012
    ..Whether urine DA is associated with phosphorus homeostasis in humans is uncertain...
  48. pmc The assessment, serial evaluation, and subsequent sequelae of acute kidney injury (ASSESS-AKI) study: design and methods
    Alan S Go
    Kaiser Permanente Northern California, Oakland, CA, USA
    BMC Nephrol 11:22. 2010
    ..Previous studies on hospital-acquired AKI have important methodological limitations, especially their retrospective study designs and limited ability to control for potential confounding factors...
  49. pmc Prevalence of chronic kidney disease in persons with undiagnosed or prehypertension in the United States
    Deidra C Crews
    Department of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA
    Hypertension 55:1102-9. 2010
    ..37 [95% CI: 2.00 to 2.81]). Chronic kidney disease is prevalent in undiagnosed and prehypertension. Earlier identification and treatment of both these conditions may prevent or delay morbidity and mortality from chronic kidney disease...
  50. ncbi request reprint Renal insufficiency in the absence of albuminuria and retinopathy among adults with type 2 diabetes mellitus
    Holly J Kramer
    Department of Preventive Medicine, Division of Nephrology, Loyola University Medical Center, Maywood, IL 60153, USA
    JAMA 289:3273-7. 2003
    ..Reduced glomerular filtration rate (GFR) among individuals with type 2 DM may not always be due to classic diabetic glomerulosclerosis, which is associated with albuminuria and retinopathy...
  51. ncbi request reprint Use of the albumin/creatinine ratio to detect microalbuminuria: implications of sex and race
    Holly J Mattix
    Renal Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    J Am Soc Nephrol 13:1034-9. 2002
    ..The use of one ACR value to define microalbuminuria may underestimate microalbuminuria in subjects with higher muscle mass (men) and possibly members of certain racial/ethnic groups...
  52. pmc Temporal changes in incidence of dialysis-requiring AKI
    Raymond K Hsu
    Department of Medicine, University of California San Francisco, San Francisco, CA 94143 0532, USA
    J Am Soc Nephrol 24:37-42. 2013
    ..In conclusion, the incidence of dialysis-requiring AKI increased rapidly in all patient subgroups in the past decade in the United States, and the number of deaths associated with dialysis-requiring AKI more than doubled...
  53. doi request reprint Design of clinical trials in acute kidney injury: a report from an NIDDK workshop--prevention trials
    Mark D Okusa
    Division of Nephrology, University of Virginia Health System, Charlottesville, VA 22908 0133, USA
    Clin J Am Soc Nephrol 7:851-5. 2012
    ..The workgroups detailed primary and secondary endpoints for studies in these groups, and explored the use of adaptive clinical trial designs for trials of novel preventive strategies to improve outcomes of patients with AKI...
  54. pmc Validation of CKD and related conditions in existing data sets: A systematic review
    Morgan E Grams
    Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA
    Am J Kidney Dis 57:44-54. 2011
    ..Our objective is to identify and synthesize published literature evaluating the accuracy of existing data sources related to kidney disease...
  55. pmc Regional variation in the incidence of dialysis-requiring AKI in the United States
    Raymond K Hsu
    Division of Nephrology, Department of Medicine, University of California, San Francisco, California, USA
    Clin J Am Soc Nephrol 8:1476-81. 2013
    ..Little is known about geographic differences in the incidence of AKI. The objective of this study was to determine if regional variation exists in the population incidence of dialysis-requiring AKI in the United States...
  56. ncbi request reprint Excess weight as a risk factor for kidney failure
    Stephanie Nguyen
    Division of Pediatric Nephrology bDivision of Nephrology, University of California, San Francisco, California 94143, USA
    Curr Opin Nephrol Hypertens 16:71-6. 2007
    ..We review recent epidemiological evidence that excess weight is an important risk factor for chronic kidney disease and end-stage renal disease...
  57. ncbi request reprint Increased prevalence of subclinical and clinical hypothyroidism in persons with chronic kidney disease
    Joan C Lo
    Divisions of Endocrinology and Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, California, USA
    Kidney Int 67:1047-52. 2005
    ..Previous studies have suggested a higher prevalence of thyroid abnormalities in persons with end-stage renal disease. However, little is known regarding the epidemiology of thyroid disorders in persons with less severe kidney dysfunction...
  58. pmc Potential role of differential medication use in explaining excess risk of cardiovascular events and death associated with chronic kidney disease: a cohort study
    Nisha Bansal
    Department of Medicine, University of California San Francisco, CA, USA
    BMC Nephrol 12:44. 2011
    ..It is unclear whether differential cardiovascular drug use explains, in part, the excess risk of cardiovascular events and death in patients with CKD and coronary heart disease (CHD)...
  59. pmc Health literacy and access to kidney transplantation
    Vanessa Grubbs
    Division of Nephrology, Department of Medicine, University of California San Francisco, California, San Francisco, CA 94143 0532, USA
    Clin J Am Soc Nephrol 4:195-200. 2009
    ..We hypothesized that inadequate health literacy in a hemodialysis population is common and is associated with poorer access to kidney transplant wait-lists...
  60. pmc End-stage renal disease preceded by rapid declines in kidney function: a case series
    Peter Lee
    Division of Nephrology, University of California, San Francisco, San Francisco, CA, USA
    BMC Nephrol 12:5. 2011
    ..Few studies have defined alternate pathways by which chronic kidney disease (CKD) patients transition into end-stage renal disease (ESRD)...
  61. pmc Sugar-sweetened beverages, serum uric acid, and blood pressure in adolescents
    Stephanie Nguyen
    Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA
    J Pediatr 154:807-13. 2009
    ..To evaluate whether sugar-sweetened beverage consumption, a significant source of dietary fructose, is associated with higher serum uric acid levels and blood pressure in adolescents...
  62. pmc Urine stability studies for novel biomarkers of acute kidney injury
    Chirag R Parikh
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, CT Program of Applied Translational Research, Yale University School of Medicine, New Haven, CT Electronic address
    Am J Kidney Dis 63:567-72. 2014
    ..We examined how variations in short-term storage and processing might affect the measurement of urine biomarkers...
  63. ncbi request reprint High prevalence of peripheral arterial disease in persons with renal insufficiency: results from the National Health and Nutrition Examination Survey 1999-2000
    ANN M O'HARE
    Staff Physician, VA Medical Center San Francisco, Box 111J Nephrology, 4150 Clement St, San Francisco, CA 94121, USA
    Circulation 109:320-3. 2004
    ..Although renal insufficiency is a recognized risk factor for coronary artery disease, little is known about the epidemiology of lower-extremity peripheral arterial disease (PAD) in persons with renal insufficiency...
  64. pmc Proteinuria and reduced glomerular filtration rate as risk factors for acute kidney injury
    Raymond K Hsu
    Division of Nephrology, University of California, San Francisco, San Francisco, California 94143 0532, USA
    Curr Opin Nephrol Hypertens 20:211-7. 2011
    ..We review recent epidemiologic evidence supporting baseline proteinuria and reduced glomerular filtration rate as risk factors for AKI...
  65. pmc Urine Biomarkers Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Kidney Injury Molecule-1 (KIM-1) Have Different Patterns in Heart Failure Exacerbation
    Meyeon Park
    University of California, San Francisco
    Biomark Insights 8:15-8. 2013
    ..We measured serial biomarker levels and evaluated the associations of these biomarkers with renal recovery in a cohort of hospitalized patients with acute heart failure exacerbation...
  66. ncbi request reprint Has acetylcysteine use changed the incidence of contrast nephropathy in hospitalized patients? A before-after study
    Sanjiv J Shah
    Department of Medicine, University of California, San Francisco, California 94143 0124, USA
    Am J Med 117:948-52. 2004
  67. ncbi request reprint Peripheral vascular disease risk factors among patients undergoing hemodialysis
    ANN M O'HARE
    Division of Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, California 94143 0532, USA
    J Am Soc Nephrol 13:497-503. 2002
    ..Future studies should prospectively examine the association of these variables identified in cross-sectional analyses with the de novo development of PVD in this population...
  68. pmc Chronic kidney disease and cognitive function in older adults: findings from the chronic renal insufficiency cohort cognitive study
    Kristine Yaffe
    Department of Psychiatry, School of Medicine, University of California at San Francisco, San Francisco, California, USA
    J Am Geriatr Soc 58:338-45. 2010
    ....
  69. pmc Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease
    Tamara Isakova
    Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA
    Kidney Int 79:1370-8. 2011
    ..Hence, FGF23 measurements may be a sensitive early biomarker of disordered phosphorus metabolism in patients with CKD and normal serum phosphate levels...
  70. pmc Relation of body mass index to urinary creatinine excretion rate in patients with coronary heart disease
    Nisha Bansal
    Department of Medicine, University of California, San Francisco, USA
    Am J Cardiol 108:179-84. 2011
    ..In conclusion, low muscle mass and low BMI are each associated with greater all-cause mortality, but low muscle mass does not appear to explain why CHD patients with low BMIs have worse prognosis...
  71. pmc Blood oxygen level-dependent (BOLD) MRI of diabetic nephropathy: preliminary experience
    Zhen J Wang
    Department of Radiology, University of California San Francisco, San Francisco, California, USA
    J Magn Reson Imaging 33:655-60. 2011
    ..To evaluate the blood oxygen level-dependent (BOLD) magnetic resonance imaging (MRI) findings in kidneys of patients with diabetic nephropathy...
  72. doi request reprint Design of clinical trials in AKI: a report from an NIDDK workshop. Trials of patients with sepsis and in selected hospital settings
    Bruce A Molitoris
    Department of Medicine, Indiana University, Indianapolis, IN, USA
    Clin J Am Soc Nephrol 7:856-60. 2012
    ..The groups considered trial design issues and discussed advantages and disadvantages of several short- and long-term primary endpoints in these patients...
  73. doi request reprint Some methodological issues in studying the long-term renal sequelae of acute kidney injury
    Kathleen D Liu
    Division of Nephrology, University of California, San Francisco, San Francisco, California 94143 0532, USA
    Curr Opin Nephrol Hypertens 18:241-5. 2009
    ..In this study, we discuss several potential solutions to these problems. Concerted efforts to address these methodological issues will propel research in this field to a higher level...
  74. ncbi request reprint Should the K/DOQI definition of chronic kidney disease be changed?
    Margaret L W Chen
    University of Washington, Seattle, WA, USA
    Am J Kidney Dis 42:623-5. 2003
  75. pmc A comparison of change in measured and estimated glomerular filtration rate in patients with nondiabetic kidney disease
    Dawei Xie
    Center for Clinical Epidemiology and Biostatistics, Philadelphia, PA 19104, USA
    Clin J Am Soc Nephrol 3:1332-8. 2008
    ..The aims of this study were to examine the concordance between use of measured GFR (mGFR) and estimated GFR (eGFR) in tracking changes in kidney function over time among patients with moderately severe chronic kidney disease...
  76. ncbi request reprint The enlarging body of evidence: obesity and chronic kidney disease
    Glenn M Chertow
    J Am Soc Nephrol 17:1501-2. 2006
  77. ncbi request reprint Anaemia among subjects with chronic renal insufficiency
    Chi yuan Hsu
    Nephrol Dial Transplant 18:623. 2003
  78. ncbi request reprint The Chronic Renal Insufficiency Cohort (CRIC) Study: Design and Methods
    Harold I Feldman
    Center for Clinical Epidemiology, Philadelphia, 19104, USA
    J Am Soc Nephrol 14:S148-53. 2003
    ..Insights from CRIC should lead to the formulation of hypotheses regarding therapy that will serve as the basis for targeted interventional trials focused on reducing the burden of CRI and CVD...
  79. ncbi request reprint Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, Oakland, CA 94612 2304, USA
    N Engl J Med 351:1296-305. 2004
    ..End-stage renal disease substantially increases the risks of death, cardiovascular disease, and use of specialized health care, but the effects of less severe kidney dysfunction on these outcomes are less well defined...
  80. doi request reprint FGF-23 and outcomes research--when physiology meets epidemiology
    Chi yuan Hsu
    N Engl J Med 359:640-2. 2008
  81. pmc Higher serum creatinine concentrations in black patients with chronic kidney disease: beyond nutritional status and body composition
    Joy Hsu
    Stanford University School of Medicine, Grant Building, S 161, Stanford, CA 94305 5114, USA
    Clin J Am Soc Nephrol 3:992-7. 2008
    ..These differences have been assumed to be largely related to race-related differences in body composition, especially muscle mass...
  82. ncbi request reprint Need for sex-specific ACR
    Holly Mattix Kramer
    Am J Kidney Dis 40:435-6; author reply 437. 2002
  83. ncbi request reprint New insights into the epidemiology of chronic kidney disease in US Asians and Pacific Islanders
    Yoshio N Hall
    Curr Opin Nephrol Hypertens 15:264-9. 2006
    ..This review highlights recent contributions to our understanding of chronic kidney disease outcomes in US Asians and Pacific Islanders...

Research Grants12

  1. Linking acute, chronic and end-stage renal disease
    Chi yuan Hsu; Fiscal Year: 2005
    ..Better understanding of the epidemiology and natural history of chronic renal insufficiency and the impact of acute renal failure will lead to improved patient management and better public health policies. ..
  2. CRIC-Plus: Study of Advanced Chronic Renal Insufficiency
    Chi yuan Hsu; Fiscal Year: 2010
    ..Aim #4: To study the effect of chronic renal insufficiency management, including the timing of dialysis initiation, on clinical outcomes after onset of end-stage renal disease. ..
  3. CRIC-Plus: Study of Advanced Chronic Renal Insufficiency
    Chi yuan Hsu; Fiscal Year: 2009
    ..Aim #4: To study the effect of chronic renal insufficiency management, including the timing of dialysis initiation, on clinical outcomes after onset of end-stage renal disease. ..
  4. CRIC-Plus: Study of Advanced Chronic Renal Insufficiency
    Chi yuan Hsu; Fiscal Year: 2007
    ..Aim #4: To study the effect of chronic renal insufficiency management, including the timing of dialysis initiation, on clinical outcomes after onset of end-stage renal disease. ..
  5. Linking acute, chronic and end-stage renal disease
    Chi yuan Hsu; Fiscal Year: 2007
    ..Better understanding of the epidemiology and natural history of chronic renal insufficiency and the impact of acute renal failure will lead to improved patient management and better public health policies. ..
  6. CRIC-Plus: Study of Advanced Chronic Renal Insufficiency
    Chi yuan Hsu; Fiscal Year: 2007
    ..Aim #4: To study the effect of chronic renal insufficiency management, including the timing of dialysis initiation, on clinical outcomes after onset of end-stage renal disease. ..
  7. Consequences of Chronic Renal Insufficiency
    Chi yuan Hsu; Fiscal Year: 2006
    ..These will contribute greatly to my development into an independent investigator. ..
  8. CRIC-Plus: Study of Advanced Chronic Renal Insufficiency
    Chi yuan Hsu; Fiscal Year: 2006
    ..Aim #4: To study the effect of chronic renal insufficiency management, including the timing of dialysis initiation, on clinical outcomes after onset of end-stage renal disease. ..
  9. Linking acute, chronic and end-stage renal disease
    Chi yuan Hsu; Fiscal Year: 2006
    ..Better understanding of the epidemiology and natural history of chronic renal insufficiency and the impact of acute renal failure will lead to improved patient management and better public health policies. ..
  10. CRIC-Plus: Study of Advanced Chronic Renal Insufficiency
    Chi yuan Hsu; Fiscal Year: 2010
    ..Aim #4: To study the effect of chronic renal insufficiency management, including the timing of dialysis initiation, on clinical outcomes after onset of end-stage renal disease. ..