Research Topics
| Robert H HowlandSummaryAffiliation: University of Pittsburgh Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Sequenced Treatment Alternatives to Relieve Depression (STAR*D). Part 1: study designRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylavania 15213, USA
J Psychosoc Nurs Ment Health Serv 46:21-4. 2008..Patients who did not reach full remission were encouraged to enter subsequent levels...- Managing common Side effects of SSRIsRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 45:15-8. 2007 - Unusual & serious adverse effects of SSRIs: recognition & managementRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 45:15-8. 2007 - Lithium: underappreciated and underused?Robert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 45:13-7. 2007..In this article, I describe the history of lithium and review important aspects of its clinical use... - Medication adherenceRobert H Howland
University of Pittsburgh, School of Medicine, Western Psychiatric Institute and Clinic, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 45:15-9. 2007..In this article, I discuss the importance of medication adherence, the factors associated with poor adherence, and some approaches for improving adherence... - Ketamin for the treatment of depressionRobert H Howland
University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
J Psychosoc Nurs Ment Health Serv 51:11-4. 2013..e., oral, intranasal,or intramuscular) needs to be determined,intravenous ketamine could be conceptualized as a clinic-based procedural therapy for treatment resistant forms of depression... 
Off-label medication useRobert H Howland
University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
J Psychosoc Nurs Ment Health Serv 50:11-3. 2012..Patients should be given adequate informed consent about how the drug is being used off label and why, along with appropriate information about known risks and side effects...- Questions to ask when selecting medicationRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 50:13-5. 2012.... - Dietary supplement drug therapies for depressionRobert H Howland
University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
J Psychosoc Nurs Ment Health Serv 50:13-6. 2012.... - The challenges of clinical psychopharmacological managementRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 50:17-20. 2012..Accurate communication among providers-and between the patient and providers-is important to avoid misinformation or misunderstandings in the care of patients with complicated problems... - Effective medication managementRobert H Howland
University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
J Psychosoc Nurs Ment Health Serv 50:13-5. 2012..Nurses have an essential role in providing effective medication management, given their direct level of patient contact and their collaborative relationship with physicians... - Now take a deep breath: inhaled loxapine for the treatment of acute agitationRobert H Howland
University of Pittsburgh School Medicine, Western Psychiatric Institute and Clinic, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 50:16-8. 2012..These studies found that inhaled loxapine was rapidly effective and generally well tolerated, although there are potential concerns about adverse pulmonary effects... - Clinical implications of chirality and stereochemistry in psychopharmacologyRobert H Howland
Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 47:17-21. 2009..Various examples of drug therapies that show the clinical importance of chirality and stereochemistry are described... - Medication holidaysRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA
J Psychosoc Nurs Ment Health Serv 47:15-8. 2009..Potential problems associated with medication holidays include the risk of destabilizing patients, difficulty in distinguishing rebound and discontinuation effects, and increasing the risk of poor medication adherence... - Effects of aging on pharmacokinetic and pharmacodynamic drug processesRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 47:15-6, 17-8. 2009.... - Prescribing psychotropic medications for elderly patientsRobert H Howland
University of Pittsburg School of Medicine, Western Psychiatric Institute and Clinic, O Hara Street, Pittburg, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 47:17-20. 2009..In their role of providing, monitoring, and coordinating treatment, nurses should be knowledgeable about the appropriate use of medication in elderly patients... - What makes a generic medication generic?Robert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 47:17-20. 2009.... - An overview of seasonal affective disorder and its treatment optionsRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
Phys Sportsmed 37:104-15. 2009..Patients should be informed of the benefits of diet and exercise. Light therapy should be clinically monitored in the same manner, as it is done for other antidepressant treatments... - Understanding chirality and stereochemistry: three-dimensional psychopharmacologyRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 47:15-8. 2009..The investigation, development, and use of stereochemically pure drugs have been encouraged by the U.S. Food and Drug Administration to improve the efficacy, tolerability, and safety of marketed drugs... - The antidepressant effects of anticholinergic drugsRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 47:17-20. 2009.... - Prescribing psychotropic medications during pregnancy and lactation: principles and guidelinesRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 47:19-23. 2009..Available treatments and their potential risks when used during pregnancy or lactation should be discussed in the context of the risks of not treating maternal psychiatric illness effectively... - Somatic therapies for seasonal affective disorderRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 47:17-20. 2009..Studies have found that bright light therapy and antidepressant medication are both effective for the treatment of SAD. Bright light therapy may also be effective for treating nonseasonal depression... - Understanding the clinical profile of a drug on the basis of its pharmacology: mirtazapine as an exampleRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 46:19-23. 2008..This knowledge also provides a rationale for choosing one drug over another for a particular patient or switching or combining drugs for treating nonresponders or alleviating side effects... - Risks and benefits of antipsychotic drugs in elderly patients with dementiaRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 46:19-23. 2008..This article highlights the studies examining the risks and benefits of antipsychotic drugs for BPSAD. Weighing small but significant risks compared with possible benefits is a complex treatment decision... - Factors predicting reduced antidepressant response: experience with the SNRI duloxetine in patients with major depressionRobert H Howland
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Ann Clin Psychiatry 20:209-18. 2008..To identify putative demographic and clinical variables that correlate with antidepressant response to the SNRI duloxetine in major depression... - Concurrent anxiety and substance use disorders among outpatients with major depression: clinical features and effect on treatment outcomeRobert H Howland
Department of Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, United States
Drug Alcohol Depend 99:248-60. 2009.... - Clinical features and functioning of patients with minor depressionRobert H Howland
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Psychother Psychosom 77:384-9. 2008..The two essential features of minor depression are that it has fewer symptoms than major depression and that it is less chronic than dysthymia. This study describes the clinical features and functioning of outpatients with minor depression... - Evaluating the bioavailability and bioequivalence of generic medicationsRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA
J Psychosoc Nurs Ment Health Serv 48:13-6. 2010..Information about generic and pharmaceutical alternative drugs can be found in the Orange Book and via Drugs@FDA... - When is a "generic" medication not really a generic?Robert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 48:13-6. 2010..Switching to a pharmaceutical alternative requires a change in prescription. Finally, the use, labeling, and cost of branded, alternative, and generic medications may be different... - Are generic medications safe and effective?Robert H Howland
University of Pittsburgh School of Medicine WPIC, 3811 O Hara Street, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 48:13-6. 2010..It is still clinically prudent to monitor a patient whose medication has been switched... - Publication bias and outcome reporting bias: agomelatine as a case exampleRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA
J Psychosoc Nurs Ment Health Serv 49:11-4. 2011..The risk of liver toxicity is also not prominently highlighted in the published literature... - A benefit-risk assessment of agomelatine in the treatment of major depressionRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, PA, USA
Drug Saf 34:709-31. 2011..Because of the unique pharmacology of agomelatine and its reported tolerability profile, it should only be considered as an alternative drug for patients who do not respond to or cannot tolerate other antidepressant drugs... - What you see depends on where you're looking and how you look at it: publication bias and outcome reporting biasRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 49:13-5. 2011.... - Drug therapies for tardive dyskinesia: part 2Robert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 49:17-20. 2011..Essential fatty acids have not been shown to be effective. Antioxidant therapies, including vitamin E, melatonin, and vitamin B₆, could conceivably be used together with other drug therapies for the treatment of TD... - Alternative drug therapies for dementiaRobert H Howland
University of Pittsburg School of Medicine, Western Psychiatric Institute and Clinic, Pittsburg, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 49:17-20. 2011.... - Vilazodone: another novel atypical antidepressant drugRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 49:19-22. 2011..However, because of its unique pharmacology and relatively benign tolerability profile, it may be a more effective alternative for patients who do not respond to or cannot tolerate currently available antidepressant drugs... - The emerging use of technology for the treatment of depression and other neuropsychiatric disordersRobert H Howland
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Ann Clin Psychiatry 23:48-62. 2011..Our objective is to review emerging technologies intended for the treatment of depression and other neuropsychiatric disorders... - Vitamin D and depressionRobert H Howland
Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 49:15-8. 2011..Current evidence does not definitively demonstrate that vitamin D deficiency is a cause of or risk for developing depression or that vitamin D is an effective therapy for depression... - Serendipity and psychopharmacologyRobert H Howland
University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
J Psychosoc Nurs Ment Health Serv 48:9-12. 2010..Nurses should be familiar with the concept of serendipity, as they often are in the best position to observe, record, and report on unexpected clinical effects in patients taking any kind of prescription or nonprescription medication... - Potential adverse effects of discontinuing psychotropic drugsRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 48:11-4. 2010..Tapering medication, rather than abruptly stopping them, can avoid or minimize the potential adverse discontinuation effects associated with most psychotropic drugs... - Therapeutic armamentarium for treating depressionRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
Postgrad Med 122:66-93. 2010..Because depressive disorders are common in primary care and other medical settings, medical practitioners should be aware of the therapeutic armamentarium available for treating depression... - Potential adverse effects of discontinuing psychotropic drugs. Part 3: Antipsychotic, dopaminergic, and mood-stabilizing drugsRobert H Howland
Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 48:11-4. 2010..If necessary, these medications should be gradually tapered to minimize all types of adverse discontinuation effects. Patients should be educated about the possible adverse effects of abrupt medication discontinuation... - Potential adverse effects of discontinuing psychotropic drugs. Part 1: Adrenergic, cholinergic, and histamine drugsRobert H Howland
Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 48:11-4. 2010..Tapering, rather than abruptly discontinuing, medication can avoid or minimize medication discontinuation effects... - The diverse clinical uses of opioid receptor drugsRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 48:11-4. 2010..This class of drugs is likely to be further developed for the treatment of addictions and mood disorders... - Drug therapies for cognitive impairment and dementiaRobert H Howland
Psychiatry, University of Pittburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 48:11-4. 2010..Other therapies discussed in this article include Ginkgo biloba, a nonprescription natural supplement, and Axona", designated by the FDA as a medical food... - A critical evaluation of the cardiac toxicity of citalopram: part 1Robert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 49:13-6. 2011..Three studies comparing citalopram overdoses to other antidepressant overdoses do not demonstrate clinically meaningful differences in cardiotoxic effects... - How are drugs approved? Part 2: ethical foundations of clinical researchRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 46:15-20. 2008..As part of a broad overview of the drug development process, this article reviews the ethical foundations of clinical research... - Antidepressants & suicide: putting the risk in perspectiveRobert H Howland
University of Pittsburgh, School of Medicine, Western Psychiatric Institute and Clinic, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 45:15-9. 2007..In this article, I will discuss this issue with the goal of putting the risk in perspective... - Challenges in the diagnosis & treatment of bipolar depression--part 2: treatment optionsRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 44:9-12. 2006 - Transdermal selegiline: a novel MAOI formulation for depressionRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 44:9-12. 2006 - Personalized drug therapy with pharmacogenetics--part 2: pharmacodynamicsRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 44:13-6. 2006 - Principles & practice of polypharmacotherapyRobert H Howland
University of Pittsburgh, School of Medicine, Western Psychiatric Institute and Clinic, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 44:13-6. 2006 - Pharmacotherapy strategies for treatment-resistant depressionRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 44:11-4. 2006 - Electroencephalography technology for predicting response to antidepressant medicationsRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 44:11-4. 2006 - Challenges in the diagnosis & treatment of bipolar depression--Part 1: assessmentRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pennsylvania, 15213, USA
J Psychosoc Nurs Ment Health Serv 44:9-12. 2006 - Limitations of evidence in the practice of evidence-based medicineRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 45:13-6. 2007..The quality of evidence is the critical component in understanding and using EBM. This article discusses the kinds and limitations of the evidence used in the practice of EBM... - Agomelatine: a novel atypical antidepressantRobert H Howland
University of Pittsburgh, School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 45:13-7. 2007..Because of its unique pharmacology and relatively benign tolerability profile, however, it may be a more effective alternative for patients who do not respond to or cannot tolerate currently available antidepressant drugs... - How are drugs approved? Part 1: the evolution of the Food and Drug AdministrationRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 46:15-9. 2008..This will provide background for two subsequent articles in this series, which will describe the ethical foundations of clinical research and hethe stages of drug development... - Glutamate-modulating drugs & the treatment of mental disordersRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 45:11-4. 2007 - Therapeutic brain stimulation for mental disordersRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 43:16-9. 2005 - Anticonvulsant drug therapiesRobert H Howland
University of Pittsburgh, School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 43:17-20. 2005 - Understanding the placebo effect. Part 1: placebo use in clinical trialsRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 46:17-20. 2008..Next month's article will describe important findings about the psychological and neurobiological processes that underlie the placebo effect... - Pharmacotherapy for psychotic depressionRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 44:13-7. 2006 - The need to guard against pharmaceutical industry influenceRobert H Howland
Department of Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
Psychiatr Serv 59:566. 2008 - How are drugs approved? Part 3. The stages of drug developmentRobert H Howland
University of Pittsburgh, School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 46:17-20. 2008..This drug development process involves the FDA, pharmaceutical companies (sponsors), clinical investigators, and institutional review boards. This article further describes this aspect of the drug development process... - Use of atypical antipsychotics in children and adolescentsRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 43:15-8. 2005 - Atypical antipsychotics: special formulations for acute agitationRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 43:14-7. 2005 - Personalized drug therapy with pharmacogenetics. Part 1: PharmacokineticsRobert H Howland
University of Pittsburgh, School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 44:13-6. 2006 - MAOI antidepressant drugsRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 44:9-12. 2006 - Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practiceMadhukar H Trivedi
Department of Psychiatry, University of Texas Southwestern Medical Center, Exchange Park Express, American General Tower, 6363 Forest Park Rd, Suite 1300, Dallas, TX 75390 9119, USA
Am J Psychiatry 163:28-40. 2006.... - Understanding the placebo effect. Part 2: underlying psychological & neurobiological processesRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 46:15-8. 2008..Understanding these effects is important for designing clinical treatment studies and interpreting their results and is highly relevant for clinical practices... - Update on newer antipsychotic drugsRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 49:13-5. 2011..Because of their unique pharmacologies and different tolerability profiles, they may be a more effective alternative for patients who do not respond to or cannot tolerate other antipsychotic drugs... - What is vagus nerve stimulation?Robert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 44:11-4. 2006 - Pharmacotherapy for psychotropic drug-related weight gainRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 46:15-8. 2008..However, even if such drugs are effective, all patients should receive ongoing dietary and physical activity counseling... - Neurosurgical approaches to therapeutic brain stimulation for treatment-resistant depressionRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 46:15-9. 2008..Deep brain stimulation and cortical brain stimulation are two such neurosurgical approaches to therapeutic brain stimulation for treatment-resistant depression... - Potential adverse effects of discontinuing psychotropic drugs: part 2: antidepressant drugsRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 48:9-12. 2010..To minimize adverse discontinuation effects and to reduce the risk of relapse or recurrence of the underlying treated condition, tapering antidepressant medication is prudent for all patients... - Sleep interventions for the treatment of depressionRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburg, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 49:17-20. 2011..Sleep deprivation, which is also associated with a transient antidepressant effect, is difficult to use in routine clinical practice but might be an appropriate strategy for treatment-resistant forms of depression... - Herbal therapiesRobert H Howland
University of Pittsburgh, School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 43:16-9. 2005 - Paliperidone extended-release tablets: a new atypical antipsychoticRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 45:15-8. 2007..Although Pal-ER does not have any major advantages or disadvantages compared with other antipsychotic drugs, it has unique pharmacological properties and may be a beneficial alternative medication for some patients... - Pharmacotherapy for insomniaRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 43:13-6. 2005 - What should patients be told about their medications?Robert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 47:17-20. 2009..The information should be practical, understandable, unbiased, and scientifically accurate, but also tailored to the individual needs of the patient... - Pharmacotherapy in personality disordersRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 45:15-9. 2007..In this article, I provide an overview of the rationale for and the role of pharmacotherapy in the treatment of personality disorders... - Vagus nerve stimulation for depression and other neuropsychiatric disordersRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 44:11-4. 2006 - Categorizing the safety of medications during pregnancy and lactationRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 47:17-20. 2009..The proposed change to the labeling system would provide more detailed, comprehensible, and practical information about the use and effects of drugs during pregnancy and lactation... - Lisdexamfetamine: a prodrug stimulant for ADHDRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, USA
J Psychosoc Nurs Ment Health Serv 46:19-22. 2008..The clinical implications stemming from LDX's unique characteristics are also discussed... - Evaluating the safety of medications during pregnancy and lactationRobert H Howland
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
J Psychosoc Nurs Ment Health Serv 47:19-22. 2009.... - Sequenced Treatment Alternatives to Relieve Depression (STAR*D). Part 2: Study outcomesRobert H Howland
University of Pittsburgh School of Medicine, Western Pychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Psychosoc Nurs Ment Health Serv 46:21-4. 2008..There were few differences among treatments within each level related to efficacy or tolerability, although patients had clear preferences for or against certain treatments... - Group comparisons of DSM-IV subtypes of chronic depression: validity of the distinctions, part 2James P McCullough
Department of Psychology, Virginia Commonwealth University, Richmond, VA 23284 2018, USA
J Abnorm Psychol 112:614-22. 2003..The authors suggest that chronic depression should be viewed as a single, broad condition that can assume a variety of clinical course configurations... - Effects of sertraline on sleep architecture in patients with depressionRipu D Jindal
Department of Psychiatry, University of Pittsburgh School of Medicine WPIC, 3811 O Hara Street, Pittsburgh, PA 15213, USA
J Clin Psychopharmacol 23:540-8. 2003..Further studies are needed to examine the effects of SSRIs in acute treatment of depressed patients with severe insomnia, and the relationship of acute changes and relapse prevention of recurrent depression... - Double-blind switch study of imipramine or sertraline treatment of antidepressant-resistant chronic depressionMichael E Thase
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
Arch Gen Psychiatry 59:233-9. 2002..Although various strategies have been proposed to treat antidepressant nonresponders, little controlled research has been published that examines prospectively the use of switching to an alternate antidepressant... - Does the duration of index episode affect the treatment outcome of major depressive disorder? A STAR*D reportWilliam S Gilmer
Asher Center for the Study and Treatment of Depressive Disorders, Northwestern University Feinberg School of Medicine, Chicago, Ill 60611, USA
J Clin Psychiatry 69:1246-56. 2008.... - Profile. Robert H. Howland, MDRobert H Howland
J Psychosoc Nurs Ment Health Serv 43:8. 2005
Research Grants
- Pharmacotherapy for Minor DepressionRobert Howland; Fiscal Year: 2004..The results of this study will have profound public health implications by improving our understanding of the efficacy of SJW and standard antidepressants for the treatment of MinorD. ..