Reuben Howden

Summary

Affiliation: University of North Carolina at Charlotte
Country: USA

Publications

  1. doi request reprint Cardiac responses to 24 hrs hyperoxia in Bmp2 and Bmp4 heterozygous mice
    R Howden
    Laboratory of Systems Physiology, Department of Kinesiology, University of North Carolina at Charlotte, Charlotte NC 28223, USA
    Inhal Toxicol 25:509-16. 2013
  2. pmc The influence of Nrf2 on cardiac responses to environmental stressors
    Reuben Howden
    Laboratory of Systems Physiology, Department of Kinesiology, University of North Carolina at Charlotte, Charlotte, NC, USA
    Oxid Med Cell Longev 2013:901239. 2013
  3. doi request reprint Genetic and environmental influences on gas exchange
    Reuben Howden
    University of North Carolina at Charlotte, Charlotte, North Carolina, USA
    Compr Physiol 2:2595-614. 2012
  4. pmc Cardiac physiologic and genetic predictors of hyperoxia-induced acute lung injury in mice
    Reuben Howden
    Department of Kinesiology, University of North Carolina at Charlotte, 28223, USA
    Am J Respir Cell Mol Biol 46:470-8. 2012
  5. pmc Nrf2 and cardiovascular defense
    Reuben Howden
    Laboratory of Systems Physiology, Department of Kinesiology, University of North Carolina at Charlotte, Charlotte, NC 28223, USA
    Oxid Med Cell Longev 2013:104308. 2013
  6. ncbi request reprint Genetic susceptibility to ozone-induced lung inflammation in animal models of asthma
    Gillian S Backus-Hazzard
    Toxicology Curriculum, University of North Carolina, Chapel Hill, North Carolina, USA
    Curr Opin Allergy Clin Immunol 4:349-53. 2004

Collaborators

Detail Information

Publications6

  1. doi request reprint Cardiac responses to 24 hrs hyperoxia in Bmp2 and Bmp4 heterozygous mice
    R Howden
    Laboratory of Systems Physiology, Department of Kinesiology, University of North Carolina at Charlotte, Charlotte NC 28223, USA
    Inhal Toxicol 25:509-16. 2013
    ..Therefore, understanding susceptibility to hyperoxia exposure is clinically important. Bone morphogenetic proteins (BMPs) 2 and 4 are involved in cardiac development and may influence responses to hyperoxia...
  2. pmc The influence of Nrf2 on cardiac responses to environmental stressors
    Reuben Howden
    Laboratory of Systems Physiology, Department of Kinesiology, University of North Carolina at Charlotte, Charlotte, NC, USA
    Oxid Med Cell Longev 2013:901239. 2013
    ..01). Results demonstrate that Nrf2 deletion increases susceptibility to change in HR and HRV responses to environmental stressors and suggest potential therapeutic strategies to prevent cardiovascular alterations...
  3. doi request reprint Genetic and environmental influences on gas exchange
    Reuben Howden
    University of North Carolina at Charlotte, Charlotte, North Carolina, USA
    Compr Physiol 2:2595-614. 2012
    ..Under these conditions, common genetic mechanisms, and their interaction with environment, help to maintain, or are detrimental to, gas exchange...
  4. pmc Cardiac physiologic and genetic predictors of hyperoxia-induced acute lung injury in mice
    Reuben Howden
    Department of Kinesiology, University of North Carolina at Charlotte, 28223, USA
    Am J Respir Cell Mol Biol 46:470-8. 2012
    ..Understanding the genetic mechanisms of these responses may have significant diagnostic clinical value...
  5. pmc Nrf2 and cardiovascular defense
    Reuben Howden
    Laboratory of Systems Physiology, Department of Kinesiology, University of North Carolina at Charlotte, Charlotte, NC 28223, USA
    Oxid Med Cell Longev 2013:104308. 2013
    ..Further studies on the cellular environments related to cardiovascular diseases that influence Nrf2 pathways are required before Nrf2 can be considered a therapeutic target for the treatment of cardiovascular diseases...
  6. ncbi request reprint Genetic susceptibility to ozone-induced lung inflammation in animal models of asthma
    Gillian S Backus-Hazzard
    Toxicology Curriculum, University of North Carolina, Chapel Hill, North Carolina, USA
    Curr Opin Allergy Clin Immunol 4:349-53. 2004
    ..This review describes the advances that have been made in understanding mechanisms of genetic susceptibility to ozone-induced inflammation, and the interaction between ozone and allergen exposure in mice and a non-human primate model...