Research Topics
| G HowardSummaryAffiliation: University of Alabama at Birmingham Country: USA Publications
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Publications
Risk Factors for Intracerebral Hemorrhage: The REasons for Geographic And Racial Differences in Stroke (REGARDS) StudyGeorge Howard
DRPH, Professor, Department of Biostatistics, UAB School of Public Health, 1665 University Blvd, Birmingham, AL 35294 0022
Stroke 44:1282-7. 2013..Risk factors for intracerebral hemorrhage (ICH) have been largely identified in case-control studies, with few longitudinal studies available...
Racial differences in the impact of elevated systolic blood pressure on stroke riskGeorge Howard
Departments of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
JAMA Intern Med 173:46-51. 2013..Between the ages 45 and 65 years, incident stroke is 2 to 3 times more common in blacks than in whites, a difference not explained by traditional stroke risk factors...
Population shifts and the future of stroke: forecasts of the future burden of strokeGeorge Howard
Department of Biostatistics, UAB School of Public Health, Birmingham, Alabama, USA
Ann N Y Acad Sci 1268:14-20. 2012..These increases are likely to present major logistical, scientific, and ethnical issues in the near future...
Association between family risk of stroke and myocardial infarction with prevalent risk factors and coexisting diseasesRichard E Kennedy
Department of Biostatistics, School of Public Health, 1665 University Boulevard, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
Stroke 43:974-9. 2012..We examined relationships between family risk of stroke and MI with risk factors for these phenotypes...
A simple, assumption-free, and clinically interpretable approach for analysis of modified Rankin outcomesGeorge Howard
Department of Biostatistics, University of Alabama at Birmingham School of Public Health Birmingham, AL 35294, USA
Stroke 43:664-9. 2012..There is debate regarding the approach for analysis of modified Rankin scale scores, the most common functional outcome scale used in acute stroke trials...
Observational epidemiology within randomized clinical trials: getting a lot for (almost) nothingGeorge Howard
Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
Prog Cardiovasc Dis 54:367-71. 2012..While these assessments of associations are not protected by randomization, with proper planning these assessments within the RCT framework can be done in a powerful and effective manner...
The association of remotely-sensed outdoor temperature with blood pressure levels in REGARDS: a cross-sectional study of a large, national cohort of African-American and white participantsShia T Kent
Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA
Environ Health 10:7. 2011..Evidence is mounting regarding the clinically significant effect of temperature on blood pressure...
Regional differences in African Americans' high risk for stroke: the remarkable burden of stroke for Southern African AmericansGeorge Howard
University of Alabama School of Public Health, Department of Biostatistics, Birmingham, AL 35294 0022, USA
Ann Epidemiol 17:689-96. 2007..There is also a "STROKE BELT" with higher stroke mortality in the southeastern United States. This study assesses if there are also geographic variations in the magnitude of the excess stroke mortality for African Americans...
Advances in population studies 2007George Howard
Department of Biostatistics, UAB School of Public Health, Birmingham, AL 35294-0022, USA
Stroke 39:283-5. 2008
Stroke and the statistics of the aspirin/clopidogrel secondary prevention trialsGeorge Howard
Department of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama 35294 0022, USA
Curr Opin Neurol 20:71-7. 2007....
Advancing the hypothesis that geographic variations in risk factors contribute relatively little to observed geographic variations in heart disease and stroke mortalityGeorge Howard
Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA
Prev Med 49:129-32. 2009..Geographic variation in risk factors may underlie geographic disparities in coronary heart disease (CHD) and stroke mortality...
Racial and geographic differences in awareness, treatment, and control of hypertension: the REasons for Geographic And Racial Differences in Stroke studyGeorge Howard
Department of Biostatistics, School of Public Health, University of Alabama, Birmingham, AL 35294, USA
Stroke 37:1171-8. 2006..Because hypertension is the leading risk factor for stroke, hypertension management (raising awareness, increasing treatment, and improving control) may reduce these disparities...
Nonconventional clinical trial designs: approaches to provide more precise estimates of treatment effects with a smaller sample size, but at a costGeorge Howard
Department of Biostatistics, University of Alabama at Birmingham School of Public Health, Birmingham, AL 35294 0022, USA
Stroke 38:804-8. 2007..The opportunities for these promising approaches, and their associated "costs," are reviewed...
Stroke symptoms in individuals reporting no prior stroke or transient ischemic attack are associated with a decrease in indices of mental and physical functioningGeorge Howard
Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Stroke 38:2446-52. 2007..Stroke symptoms in the absence of recognized stroke are common, but potential associated dysfunctions have not been described...
Imputation of incident events in longitudinal cohort studiesGeorge Howard
Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Ryals Building, Room 327D, 1665 University Boulevard, Birmingham, AL 35294 0022, USA
Am J Epidemiol 174:718-26. 2011....
Traditional risk factors as the underlying cause of racial disparities in stroke: lessons from the half-full (empty?) glassGeorge Howard
Department of Biostatistics, School of Public Health, 1665 University Blvd, University of Alabama at Birmingham, Birmingham, AL, USA
Stroke 42:3369-75. 2011..Black/white disparities in stroke incidence are well documented, but few studies have assessed the contributions to the disparity. Here we assess the contribution of "traditional" risk factors...
Ethnic disparities in stroke: the scope of the problemG Howard
Department of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama 32594 0022, USA
Ethn Dis 11:761-8. 2001..As such, efforts to reduce ethnic disparities in stroke mortality have been unsuccessful...
Decline in US stroke mortality: an analysis of temporal patterns by sex, race, and geographic regionG Howard
Department of Biostatistics, University of Alabama at Birmingham, Birmingham AL 35294, USA
Stroke 32:2213-20. 2001..Here, we assess whether the race-sex-region groups have participated equally in this decline and whether there are groups in which stroke mortality rates are still declining, and we predict how these rates will eventually differ...
Why is environmental tobacco smoke more strongly associated with coronary heart disease than expected? A review of potential biases and experimental dataG Howard
Department of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama 35294 0022, USA
Environ Health Perspect 107:853-8. 1999..Because exposure to ETS affects multiple physiologic pathways, it appears biologically plausible that ETS could cause the substantial increase in CHD risk that has been observed in epidemiologic studies...
Is Bayesian analysis ready for use in phase III randomized clinical trials? Beware the sound of the sirensGeorge Howard
Department of Biostatistics, University of Alabama at Birmingham, AL 35294 0022, USA
Stroke 36:1622-3. 2005
The confounding of race and geography: how much of the excess stroke mortality among African Americans is explained by geography?Dongyan Yang
Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, Ala, USA
Neuroepidemiology 23:118-22. 2004..e., race and geography are 'confounded'). In this paper we estimate the proportion of the excess stroke mortality among African Americans that is attributable to geography...
The reasons for geographic and racial differences in stroke study: objectives and designVirginia J Howard
Department of Epidemiology, University of Alabama at Birmingham, USA
Neuroepidemiology 25:135-43. 2005..Participants are followed via telephone at 6-month intervals for identification of stroke events. The novel aspects of the REGARDS study allow for the creation of a national cohort to address geographic and ethnic differences in stroke...
Early rheumatoid arthritis in African-Americans: the CLEAR RegistryS L Bridges
Departments of Medicine and Microbiology, Division of Clinical Immu nology and Rheumatology, University of Alabama at Birmingham, 415 Lyons Harrison Research Building, 701 19th Street South, Birmingham, Alabama 35294 0007, USA
Clin Exp Rheumatol 21:S138-45. 2003..The Consortium for the Longitudinal Evaluation of African-Americans with early RA (CLEAR) Registry, a collaborative effort among four institutions in the southeast USA, will hopefully provide a useful resource to study these issues...
Association of higher diastolic blood pressure levels with cognitive impairmentG Tsivgoulis
Comprehensive Stroke Center, University of Alabama at Birmingham, RWUH M226, 1530 3rd Avenue S, Birmingham, AL 35294 3280, USA
Neurology 73:589-95. 2009..We evaluated the cross-sectional relationship of blood pressure (BP) components with cognitive impairment after adjusting for potential confounders...
Race and gender differences in perceived caregiver availability for community-dwelling middle-aged and older adultsDavid L Roth
Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, 327 Ryals Building, Birmingham, AL 35294 0022, USA
Gerontologist 47:721-9. 2007..This study examined race and gender differences in perceived informal caregiver availability for participants aged 45 and older in a large national epidemiological study...
Tooth loss, systemic inflammation, and prevalent stroke among participants in the reasons for geographic and racial difference in stroke (REGARDS) studyZhiying You
Department of Biostatistics, University of Alabama at Birmingham, United States
Atherosclerosis 203:615-9. 2009....
Understanding racial disparities in hypertension control: intensity of hypertension medication treatment in the REGARDS studyMonika M Safford
University of Alabama at Birmingham, Birmingham, USA
Ethn Dis 17:421-6. 2007..Intensity of hypertension treatment may play a role. We examined whether AA with treated hypertension received less-intense medication regimens than EA, as reflected in the number of antihypertensive medication classes...
A new estimate of family disease history providing improved prediction of disease risksRui Feng
Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Stat Med 28:1269-83. 2009..The results show that assessing family history can improve the prediction of disease risks and the SLFS has strongest positive associations with both myocardial infarction and stroke...
Racial differences in Parkinson's disease medication use in the reasons for geographic and racial differences in stroke cohort: a cross-sectional studyTalene A Yacoubian
Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA
Neuroepidemiology 33:329-34. 2009..We evaluated data from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study to describe potential racial differences in PD prevalence...
Population-based fracture risk assessment and osteoporosis treatment disparities by race and genderJeffrey R Curtis
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham 35294, USA
J Gen Intern Med 24:956-62. 2009..Undertreatment of osteoporosis has been recognized as a common problem in selected patient subgroups. However, primary prevention has been hampered by limited risk assessment tools that can be applied to large populations...
The association between self-reported tooth loss and cognitive function in the REasons for Geographic And Racial Differences in Stroke study: an assessment of potential pathwaysJonathan C Matthews
Institute of Oral Health Research, School of Dentistry, University of Alabama at Birmingham, USA
J Am Dent Assoc 142:379-90. 2011..Several mechanisms may associate tooth loss and related oral inflammation with cognitive impairment. The authors studied the relationship between tooth loss and cognitive function...
Disparities in stroke incidence contributing to disparities in stroke mortalityVirginia J Howard
Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, 1665 University Boulevard, Birmingham, AL 35294 0022, USA
Ann Neurol 69:619-27. 2011..We provide national estimates of stroke incidence by race and region, contrasting these to publicly available stroke mortality data...
Statistical power, the Belmont report, and the ethics of clinical trialsSara H Vollmer
Department of Philosophy, UAB Center for Ethics and Values in the Sciences, 900 13th St South, 414A, Birmingham, AL 35294 1260, USA
Sci Eng Ethics 16:675-91. 2010..The paper also argues that good trial design is required for true informed consent...
Is there a role for echocardiography in intracerebral haemorrhage?Karen C Albright
Comprehensive Stroke Center, University of Alabama at Birmingham, Birmingham, AL, USA
Int J Stroke 5:383-4. 2010..Further study is required to determine whether angiotensin directed therapies provide optimal secondary prevention in ICH patients with HHD...
Kidney function, albuminuria, and all-cause mortality in the REGARDS (Reasons for Geographic and Racial Differences in Stroke) studyDavid G Warnock
Division of Nephrology, Department of Medicine, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA
Am J Kidney Dis 56:861-71. 2010..Chronic kidney disease and albuminuria are associated with increased risk of all-cause mortality...
The association of statin use and statin type and cognitive performance: analysis of the reasons for geographic and racial differences in stroke (REGARDS) studyStephen P Glasser
University of Alabama at Birmingham, Division of Preventive Medicine, Birmingham, Alabama 35205, USA
Clin Cardiol 33:280-8. 2010..Statin use and type have been variably associated with impaired or improved cognitive performance...
Awareness, treatment, and control of vascular risk factors among stroke survivorsDavid A Brenner
Department of Biostatistics, University of Alabama at Birmingham School of Public Health, Birmingham, Mobile, Alabama, USA
J Stroke Cerebrovasc Dis 19:311-20. 2010..We therefore assessed the prevalence, treatment, and control of hypertension, diabetes, and dyslipidemia among stroke survivors versus stroke-free control subjects...
Prevalence of hypertension by duration and age at exposure to the stroke beltVirginia J Howard
Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
J Am Soc Hypertens 4:32-41. 2010..That adolescence and early adulthood periods are more predictive than residence in the stroke belt for most recent 20-year period suggests community and environmental strategies to prevent hypertension need to start earlier in life...
Reduced medication access: a marker for vulnerability in US stroke survivorsDeborah A Levine
Deep South Center on Effectiveness Research, Birmingham VA Medical Center, AL, USA
Stroke 38:1557-64. 2007..Medication access is crucial to secondary stroke prevention. We assessed medication access and associated barriers to care across region and time in a national sample of US stroke survivors...
Comparing longitudinal binary outcomes in an observational oral health studyBrent J Shelton
Department of Biostatistics, School of Public Health, The University of Alabama at Birmingham, 1665 University Boulevard, RPHB 327 H, Birmingham, AL 35294 0022, U S A
Stat Med 22:2057-70. 2003..Our application of sample selection models to binary longitudinal observational outcome data should serve as impetus for increased utilization of this promising set of models to other health outcomes studies...
Race and gender differences in 1-year outcomes for community-dwelling stroke survivors with family caregiversDavid L Roth
Department of Biostatistics, UAB, 1530 3rd Avenue South, Birmingham, AL 35294 0022, USA
Stroke 42:626-31. 2011..Race and gender differences in 1-year stroke outcomes were examined using an epidemiologically derived sample of first-time stroke survivors from the national REasons for Geographic and Racial Differences in Stroke (REGARDS) study...
Chronic disease mortality in a cohort of smokeless tobacco usersNeil A Accortt
Department of Epidemiology and International Health, School of Public Health, University of Alabama at Birmingham, 35294, USA
Am J Epidemiol 156:730-7. 2002..Furthermore, combined use of smokeless tobacco and cigarettes did not increase overall mortality beyond that expected from use of the individual products...
Prevalence of chronic kidney disease and anemia among participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Cohort Study: baseline resultsDavid G Warnock
Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
Kidney Int 68:1427-31. 2005
An approach to coordinate efforts to reduce the public health burden of stroke: the Delta States Stroke ConsortiumVirginia J Howard
School of Public Health, University of Alabama at Birmingham, 35294 0022, USA
Prev Chronic Dis 1:A19. 2004..The Delta States Stroke Consortium members propose that together these domains and activities define a structure to guide interventions to reduce the public health burden of stroke in this region...
Does differential prophylactic aspirin use contribute to racial and geographic disparities in stroke and coronary heart disease (CHD)?Stephen P Glasser
Preventive Medicine and Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama 35205, USA
Prev Med 47:161-6. 2008..Aspirin use may reduce the risk of stroke and coronary heart disease. Differential use for vascular prophylaxis may contribute to racial and geographic disparities in stroke and coronary heart disease morbidity or mortality...
Meta-analysis of data from the six primary prevention trials of cardiovascular events using aspirinAlfred A Bartolucci
The Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA
Am J Cardiol 98:746-50. 2006..In conclusion, primary prevention with aspirin decreased the risk of total CHD, nonfatal MI, and total CV events, but there were no significant differences in the incidences of stroke or CV mortality...
Changes in plasma homocyst(e)ine in the acute phase after strokeVirginia J Howard
Department of Epidemiology and International Health, University of Alabama at Birmingham, Birmingham, Ala 35294 0022, USA
Stroke 33:473-8. 2002..Although the literature suggests that H(e) increases from the acute to the convalescent phase after a stroke, it is not known whether H(e) changes within the acute period...
Cognitive status, stroke symptom reports, and modifiable risk factors among individuals with no diagnosis of stroke or transient ischemic attack in the REasons for Geographic and Racial Differences in Stroke (REGARDS) StudyVirginia G Wadley
Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 2041, USA
Stroke 38:1143-7. 2007..This study evaluates relationships among cognitive status, stroke symptom reports, and cardiovascular and behavioral factors...
Cancer incidence among a cohort of smokeless tobacco users (United States)Neil A Accortt
Medical Statistics Section, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
Cancer Causes Control 16:1107-15. 2005..Smokeless tobacco (ST) use remains a prevalent form of tobacco use among certain US populations. The purpose of this paper is to clarify its role in cancer development...
Prehypertension, racial prevalence and its association with risk factors: Analysis of the REasons for Geographic And Racial Differences in Stroke (REGARDS) studyStephen P Glasser
Department of Internal Medicine, University of Alabama at Birmingham, USA
Am J Hypertens 24:194-9. 2011..There are few available data on the epidemiology of prehypertension (preHTN). To determine racial, clinical, and demographic differences in the prevalence of preHTN and its cross-sectional association with vascular risk factors...
Prospective associations of fasting insulin, body fat distribution, and diabetes with risk of ischemic stroke. The Atherosclerosis Risk in Communities (ARIC) Study InvestigatorsA R Folsom
Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
Diabetes Care 22:1077-83. 1999..We tested the hypothesis that diabetes, body fat distribution, and (in nondiabetic subjects) fasting insulin levels are positively associated with ischemic stroke incidence in the general population...
Need to educate primary caregivers about the risk factor profile of smokeless tobacco usersNeil A Accortt
University of Alabama at Birmingham, Biostatics Unit, Comprehensive Cancer Center, USA
J Cancer Educ 20:222-8. 2005..Identification of ST users should prompt the physician or dentist to inquire about other chronic disease risk factors that the patient may have and to educate the ST using patient about ways to reduce their risk of cancer...
Age-related underutilization of angiotensin-converting enzyme inhibitors in older hospitalized heart failure patientsAli Ahmed
Department of Medicine, School of Medicine, Center for Aging, University of Alabama at Birmingham, USA
South Med J 95:703-10. 2002..Opportunities remain to increase the use of ACE inhibitors in older patients with heart failure...
National variation in United States sepsis mortality: a descriptive studyHenry E Wang
Department of Emergency Medicine, University of Alabama at Birmingham, USA
Int J Health Geogr 9:9. 2010..We defined sepsis deaths as deaths attributed to an infection, classified according to the International Classification of Diseases, Version 10. We calculated national and state age-adjusted sepsis-attributed mortality rates...
Adjuvant radiotherapy for pancreatic cancer is associated with a survival benefit primarily in stage IIB patientsJohn S Moody
Department of Radiation Oncology, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294 3300, USA
J Gastroenterol 44:84-91. 2009..This study examines the survival impact of postoperative RT in a large population-based database...
Age-related underutilization of left ventricular function evaluation in older heart failure patientsAli Ahmed
Department of Medicine, School of Medicine, Center for Aging, University of Alabama at Birmingham, USA
South Med J 95:695-702. 2002..Left ventricular function evaluation should be performed in all patients with heart failure. Considerable opportunities exist for improving care among hospitalized Medicare beneficiaries diagnosed with heart failure...
Association of consultation between generalists and cardiologists with quality and outcomes of heart failure careAli Ahmed
aDivision of Gerontology and Geriatric Medicine, Department of Medicine, School of Medicine, Center for Aging, University of Alabama at Birmingham, USA
Am Heart J 145:1086-93. 2003..54; 95% CI, 0.34-0.86). CONCLUSION: Collaboration between generalists and cardiologists, rather than solo care by either, was associated with better HF processes and outcomes of care...
Genetic association of htSNPs across the major histocompatibility complex with rheumatoid arthritis in an African-American populationR J Reynolds
Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham UAB, Birmingham, AL 35294 2182, USA
Genes Immun 11:94-7. 2010..28 in cases versus 0.27 in controls). This study points to the potential association of a SNP in the HLA-DOA gene with RA in African Americans, but also underscores the importance of replication of findings in larger patient cohorts...
Cerebrovascular diseases as primary hospital discharge diagnoses: national trend (1970-2000) among older adultsAli Ahmed
Division of Gerontology and Geriatric Medicine, Department of Medicine, School of Medicine, University of Alabama at Birmingham, USA
J Gerontol A Biol Sci Med Sci 60:1328-32. 2005..However, the absolute number of hospitalizations due to cerebrovascular disease increased considerably, with potential for serious social, financial, and public health implications for the coming decades...
Value of orthopnea, paroxysmal nocturnal dyspnea, and medications in prospective population studies of incident heart failureO James Ekundayo
University of Alabama at Birmingham, Birmingham, AL, USA
Am J Cardiol 104:259-64. 2009....
PaCO2 and neurodevelopment in extremely low birth weight infantsLara A McKee
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA
J Pediatr 155:217-21.e1. 2009..To determine the relationship between PaCO2 in the first 4 days of life and neurodevelopment at 18 to 22 months...
Clinical trial design issues: at least 10 things you should look for in clinical trialsStephen P Glasser
Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
J Clin Pharmacol 46:1106-15. 2006..Each of these is discussed, and examples of published articles are used to highlight the main points...
Care seeking after stroke symptomsVirginia J Howard
Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
Ann Neurol 63:466-72. 2008..To assess risk factors associated with care for stroke symptoms...
Stage-specific survival differences associated with postoperative radiotherapy for gastrointestinal cancersJohn S Moody
Department of Radiation Oncology, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA
J Gastrointest Cancer 39:86-99. 2008..To study the frequency and effect associated with postoperative radiotherapy (RT) for patients with resected gastrointestinal (GI) cancers...
Risk factors for progression of common carotid atherosclerosis: the Atherosclerosis Risk in Communities Study, 1987-1998Lloyd E Chambless
Department of Biostatistics, School of Public Health, University of North Carolina, Chapel Hill, NC 27514 4145, USA
Am J Epidemiol 155:38-47. 2002..In summary, established risk factors for coronary heart disease are associated with the rate of change of subclinical atherosclerosis...
Standards for statistical models used for public reporting of health outcomes: an American Heart Association Scientific Statement from the Quality of Care and Outcomes Research Interdisciplinary Writing Group: cosponsored by the Council on Epidemiology anHarlan M Krumholz
Circulation 113:456-62. 2006....
An assessment of the joint associations of aspirin and statin use with C-reactive protein concentrationMatt Fisher
Bayer HealthCare, Morristown, NJ 07962 1910, USA
Am Heart J 156:106-11. 2008..The use of aspirin alone and statins alone has been shown to reduce markers of inflammation, including C-reactive protein (CRP); however, their combination has been poorly studied...
Factors contributing to global cognitive impairment in heart failure: results from a population-based cohortPatrick M Pullicino
Kent Institute of Medicine and Health Sciences, University of Kent, Canterbury, Kent, United Kingdom
J Card Fail 14:290-5. 2008..Heart failure (HF) and cognitive impairment are both common in older adults. However, the association between the two has not been well studied...
A propensity-matched study of hypertension and increased stroke-related hospitalization in chronic heart failureGerasimos S Filippatos
University of Athens, Athens, Greece
Am J Cardiol 101:1772-6. 2008..81; p=0.044). In conclusion, a history of hypertension was associated with increased risk of hospitalization for stroke among patients with heart failure who were balanced in all measured baseline covariates, including blood pressure...
The HLA-DRB1 shared epitope is associated with susceptibility to rheumatoid arthritis in African Americans through European genetic admixtureLaura B Hughes
University of Alabama at Birmingham 35294 2182, USA
Arthritis Rheum 58:349-58. 2008....
Primary prevention of high blood cholesterol concentrations in the United StatesDavid C Goff
Department of Public Health Sciences, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1063, USA
Arch Intern Med 162:913-9. 2002..Greater understanding of this dramatic shift in the distribution of TC levels could support future prevention efforts...
Site-specific progression of carotid artery intimal-medial thicknessMark A Espeland
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Atherosclerosis 171:137-43. 2003..To characterize the intercorrelation of changes in intimal-medial thickness (IMT) among carotid artery sites and examine the influence of diabetes and sex on these correlations...
Insulin resistance and hypertension: the Insulin Resistance Atherosclerosis studyMohammed F Saad
Division of Clinical Epidemiology, Department of Medicine, UCLA Medical School, 924 Westwood Blvd, Suite 335 Mail Box 15, Los Angeles, Calif 90024, USA
Hypertension 43:1324-31. 2004..Neither insulin resistance nor insulinemia was related to hypertension or blood pressure in patients with type 2 diabetes in the 3 ethnic groups...
Kidney function and cognitive impairment in US adults: the Reasons for Geographic and Racial Differences in Stroke (REGARDS) StudyManjula Kurella Tamura
Department of Medicine, University of California San Francisco, San Francisco, CA, USA
Am J Kidney Dis 52:227-34. 2008..The association between kidney function and cognitive impairment has not been assessed in a national sample with a wide spectrum of kidney disease severity...
Racial differences in the prevalence of chronic kidney disease among participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Cohort StudyWilliam McClellan
Emory University School of Medicine, Renal Division, Atlanta, Georgia 30322, USA
J Am Soc Nephrol 17:1710-5. 2006..Factors that are responsible for the increasing prevalence of severely impaired kidney function among black patients remain to be determined...
Prevalence and characteristics of a family history of end-stage renal disease among adults in the United States population: Reasons for Geographic and Racial Differences in Stroke (REGARDS) renal cohort studyWilliam McClellan
Georgia Medical Care Foundation, Emory University, Suite 200, Executive Park South NE, Atlanta, GA 30329 2224, USA
J Am Soc Nephrol 18:1344-52. 2007..If confirmed, then these findings suggest that individuals with FH-ESRD may benefit from interventions to improve the detection and treatment of chronic kidney disease risk factors such as diabetes and obesity...
Prevention Conference VII: Obesity, a worldwide epidemic related to heart disease and stroke: Group II: age-dependent risk factors for obesity and comorbiditiesSachiko T St Jeor
Circulation 110:e471-5. 2004
Simple anthropometric measures correlate with metabolic risk indicators as strongly as magnetic resonance imaging-measured adipose tissue depots in both HIV-infected and control subjectsRebecca Scherzer
Northern California Institute for Research and Education, San Francisco, CA, USA
Am J Clin Nutr 87:1809-17. 2008..Studies in persons without HIV infection have compared percentage body fat (%BF) and waist circumference as markers of risk for the complications of excess adiposity, but only limited study has been conducted in HIV-infected subjects...
Carotid artery stenting is associated with increased complications in octogenarians: 30-day stroke and death rates in the CREST lead-in phaseRobert W Hobson
University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark 07101, USA
J Vasc Surg 40:1106-11. 2004..The occurrence of stroke and death was reviewed by an independent clinical events committee...
Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing CouncLarry B Goldstein
Circulation 113:e873-923. 2006..CONCLUSIONS: Extensive evidence is available identifying a variety of specific factors that increase the risk of a first stroke and providing strategies for reducing that risk...
Anti-cyclic citrullinated peptide antibody and rheumatoid factor isotypes in African Americans with early rheumatoid arthritisTed R Mikuls
University of Nebraska Medical Center, Omaha Veterans Administration Medical Center, Omaha, NE, USA
Arthritis Rheum 54:3057-9. 2006
Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing CouncLarry B Goldstein
Stroke 37:1583-633. 2006..CONCLUSIONS: Extensive evidence is available identifying a variety of specific factors that increase the risk of a first stroke and providing strategies for reducing that risk...
Comparison of dual-energy X-ray absorptiometry and magnetic resonance imaging-measured adipose tissue depots in HIV-infected and control subjectsRebecca Scherzer
University of California, San Francisco, CA 94121, USA
Am J Clin Nutr 88:1088-96. 2008....
Air pollution and cardiovascular disease: a statement for healthcare professionals from the Expert Panel on Population and Prevention Science of the American Heart AssociationRobert D Brook
Circulation 109:2655-71. 2004..Practical recommendations for healthcare providers and their patients are outlined. In the final section, suggestions for future research are made to address a number of remaining scientific questions...
Second births among teenage mothers: program results and statistical methodsLorraine V Klerman
Heller School for Social Policy and Management, Brandeis University, p O Box 9110 MS 035, Waltham, Massachusetts 02454 9110, USA
J Adolesc Health 32:452-5. 2003..Delaying second pregnancies among teenagers requires intensive efforts. Survival analysis is a more accurate and useful way of presenting program results than simple analysis of the proportion of women with a second birth...
Research Grants
- Etiology of Geographic and Racial Differences in StrokeGeorge Howard; Fiscal Year: 2001....
- Etiology of Geographic and Racial Differences in StrokeGeorge Howard; Fiscal Year: 2007..abstract_text> ..
