Research Topics
| M HornigSummaryAffiliation: University of California Country: USA Publications
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Publications
Autoantibody disturbances in affective disorders: a function of age and gender?M Hornig
Laboratory for the Study of Emerging Diseases, University of California Irvine, 92697 4292, USA
J Affect Disord 55:29-37. 1999..However, association of autoimmunity with affective subtypes, mood state, psychotropic medications, age, and gender has not been extensively explored...
Infectious and immune factors in the pathogenesis of neurodevelopmental disorders: epidemiology, hypotheses, and animal modelsM Hornig
Emerging Diseases Laboratory, Gillespie Neuroscience Research Facility, University of California, Irvine, California 92697 4292, USA
Ment Retard Dev Disabil Res Rev 7:200-10. 2001....
Infectious and immune factors in neurodevelopmental damageM Hornig
Center for Immunopathogenesis and Infectious Diseases, Dept of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
Mol Psychiatry 7:S34-5. 2002
Passive transfer of streptococcus-induced antibodies reproduces behavioral disturbances in a mouse model of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infectionK Yaddanapudi
Center for Infection and Immunity and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Mol Psychiatry 15:712-26. 2010..This work provides insights into PANDAS pathogenesis and may lead to new strategies for identification and treatment of children at risk for autoimmune brain disorders...
Borna disease virus infection of adult and neonatal rats: models for neuropsychiatric diseaseM Hornig
Laboratory for the Study of Emerging Diseases, 3101 Gillespie Neuroscience Research Facility, University of California, Irvine, CA 92697-4292, USA
Curr Top Microbiol Immunol 253:157-77. 2001..1999), Hornig et al. (1999), and Weissenböck et al. (2000); and alterations in cytokine gene expression have been reported by Hornig et al. (1999), Plata-Salaman et al. (1999) and Sauder et al. (1999)...
Bornavirus tropism and targeted pathogenesis: virus-host interactions in a neurodevelopmental modelM Hornig
Emerging Diseases Laboratory, Gillespie Neuroscience Research Facility, University of California, Irvine, California 92697, USA
Adv Virus Res 56:557-82. 2001....
Neurotoxic effects of postnatal thimerosal are mouse strain dependentM Hornig
Jerome L and Dawn Greene Infectious Disease Laboratory, Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Mol Psychiatry 9:833-45. 2004..Strains resistant to autoimmunity, C57BL/6J and BALB/cJ, were not susceptible. These findings implicate genetic influences and provide a model for investigating thimerosal-related neurotoxicity...
Absence of evidence for bornavirus infection in schizophrenia, bipolar disorder and major depressive disorderM Hornig
Center for Infection and Immunity, Columbia University Mailman School of Public Health, New York, NY 10032, USA
Mol Psychiatry 17:486-93. 2012..Our results argue strongly against a role for BDV in the pathogenesis of these psychiatric disorders...
Metallothioneins and zinc dysregulation contribute to neurodevelopmental damage in a model of perinatal viral infectionBrent L Williams
Greene Infectious Disease Laboratory, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Brain Pathol 16:1-14. 2006..Abnormal zinc metabolism and mechanisms of neuroplasticity may contribute to the pathogenesis of disease in this model, raising more general implications for neurodevelopmental damage following viral infections in early life...
Spatiotemporal analysis of purkinje cell degeneration relative to parasagittal expression domains in a model of neonatal viral infectionBrent L Williams
Jerome L and Dawn Greene Infectious Disease Laboratory, Mailman School of Public Health, Columbia University, 722 West 168th Street, Rm 1801, New York, NY 10032, USA
J Virol 81:2675-87. 2007..These findings suggest a differential vulnerability of PC subsets during the early stages of virus-induced neurodegeneration...
Hippocampal poly(ADP-Ribose) polymerase 1 and caspase 3 activation in neonatal bornavirus infectionBrent L Williams
Center for Infection and Immunity, Mailman School of Public Health, Columbia University, 722 West 168th Street, Room 1801, New York, NY 10032, USA
J Virol 82:1748-58. 2008..These results implicate aberrant zinc homeostasis, PARP-1, and caspase 3 activation as contributing factors in hippocampal neurodegeneration in NBD...
Borna disease virusMady Hornig
Center for Immunopathogenesis and Infectious Diseases, Mailman School of Public Health, Columbia University, New York, New York 10025, USA
J Neurovirol 9:259-73. 2003....
