Florence Horn

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Collecting and harvesting biological data: the GPCRDB and NucleaRDB information systems
    F Horn
    Department of Cellular and Molecular Pharmacology, UCSF, Box 0450, San Francisco, CA 94143 0450, USA
    Nucleic Acids Res 29:346-9. 2001
  2. ncbi request reprint Automated extraction of mutation data from the literature: application of MuteXt to G protein-coupled receptors and nuclear hormone receptors
    Florence Horn
    Department of Cellular and Molecular Pharmacology, University of California of San Francisco, 94143, USA
    Bioinformatics 20:557-68. 2004
  3. pmc Automatic extraction of protein point mutations using a graph bigram association
    Lawrence C Lee
    Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California, United States of America
    PLoS Comput Biol 3:e16. 2007
  4. pmc GPCRDB information system for G protein-coupled receptors
    Florence Horn
    Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, California, USA
    Nucleic Acids Res 31:294-7. 2003
  5. pmc Phosphorylation and intramolecular stabilization of the ligand binding domain in the nuclear receptor steroidogenic factor 1
    Marion Desclozeaux
    Departments of Physiology Cellular and Molecular Pharmacology Biochemistry and Biophysics University of California San Francisco, San Francisco, California 94143 0444, USA
    Mol Cell Biol 22:7193-203. 2002
  6. pmc NRSAS: Nuclear Receptor Structure Analysis Servers
    Emmanuel Bettler
    CMBI KUN, PO Box 9010, 6500 GL Nijmegen, The Netherlands
    Nucleic Acids Res 31:3400-3. 2003
  7. ncbi request reprint A family-based approach reveals the function of residues in the nuclear receptor ligand-binding domain
    Simon Folkertsma
    CMBI, University of Nijmegen, PO Box 9010, 6500 GL Nijmegen, The Netherlands
    J Mol Biol 341:321-35. 2004
  8. ncbi request reprint GRIS: glycoprotein-hormone receptor information system
    Joost Van Durme
    Institut de Recherche Interdisciplinaire en Biologie Humaine et Moleculaire, Universite Libre de Bruxelles, Campus Erasme, Route de Lennik 808, B 1070 Brussels, Belgium
    Mol Endocrinol 20:2247-55. 2006

Collaborators

  • Robert J Fletterick
  • Fabien Campagne
  • FRED COHEN
  • Roland Krause
  • Joost Van Durme
  • Emmanuel Bettler
  • Lawrence C Lee
  • Gert Vriend
  • Simon Folkertsma
  • Marion Desclozeaux
  • Gilbert Vassart
  • Sabine Costagliola
  • Paula van Noort
  • Jacob de Vlieg
  • Henk Jan Joosten
  • Laerte Oliveira
  • Gerrit Vriend
  • Wilco Fleuren
  • Irina N Krylova
  • Holly A Ingraham

Detail Information

Publications8

  1. pmc Collecting and harvesting biological data: the GPCRDB and NucleaRDB information systems
    F Horn
    Department of Cellular and Molecular Pharmacology, UCSF, Box 0450, San Francisco, CA 94143 0450, USA
    Nucleic Acids Res 29:346-9. 2001
    ..The NucleaRDB was started recently as an application of the concept for the generalization of this technology. The GPCRDB is available via the WWW at http://www.gpcr.org/7tm/ and the NucleaRDB at http://www.receptors.org/NR/...
  2. ncbi request reprint Automated extraction of mutation data from the literature: application of MuteXt to G protein-coupled receptors and nuclear hormone receptors
    Florence Horn
    Department of Cellular and Molecular Pharmacology, University of California of San Francisco, 94143, USA
    Bioinformatics 20:557-68. 2004
    ..3% of the GPCR point mutations with a specificity of 87.9%, and 64.5% of the NR point mutations with a specificity of 85.8%. MuteXt routinely analyzes 100 electronic articles in approximately 1 h...
  3. pmc Automatic extraction of protein point mutations using a graph bigram association
    Lawrence C Lee
    Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California, United States of America
    PLoS Comput Biol 3:e16. 2007
    ..73. We believe the graph bigram search metric to be a significant improvement over previous search metrics for point mutation extraction and to be applicable to text-mining application requiring the association of words...
  4. pmc GPCRDB information system for G protein-coupled receptors
    Florence Horn
    Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, California, USA
    Nucleic Acids Res 31:294-7. 2003
    ..The GPCRDB is updated automatically once every 4-5 months and is freely accessible at http://www.gpcr.org/7tm/...
  5. pmc Phosphorylation and intramolecular stabilization of the ligand binding domain in the nuclear receptor steroidogenic factor 1
    Marion Desclozeaux
    Departments of Physiology Cellular and Molecular Pharmacology Biochemistry and Biophysics University of California San Francisco, San Francisco, California 94143 0444, USA
    Mol Cell Biol 22:7193-203. 2002
    ....
  6. pmc NRSAS: Nuclear Receptor Structure Analysis Servers
    Emmanuel Bettler
    CMBI KUN, PO Box 9010, 6500 GL Nijmegen, The Netherlands
    Nucleic Acids Res 31:3400-3. 2003
    ..The Nuclear Receptor Structure Analysis Servers (NRSAS) are freely accessible at http://www.cmbi.kun.nl/NR/servers/html/ and in-house copies can be obtained upon request...
  7. ncbi request reprint A family-based approach reveals the function of residues in the nuclear receptor ligand-binding domain
    Simon Folkertsma
    CMBI, University of Nijmegen, PO Box 9010, 6500 GL Nijmegen, The Netherlands
    J Mol Biol 341:321-35. 2004
    ..The results shed light on the nuclear receptor family that is involved in processes ranging from cancer to infertility, and that is one of the more important targets in the pharmaceutical industry...
  8. ncbi request reprint GRIS: glycoprotein-hormone receptor information system
    Joost Van Durme
    Institut de Recherche Interdisciplinaire en Biologie Humaine et Moleculaire, Universite Libre de Bruxelles, Campus Erasme, Route de Lennik 808, B 1070 Brussels, Belgium
    Mol Endocrinol 20:2247-55. 2006
    ..Users can upload new mutations. GRIS is freely accessible at http://gris.ulb.ac.be/...