Affiliation: University of California
- Collecting and harvesting biological data: the GPCRDB and NucleaRDB information systemsF Horn
Department of Cellular and Molecular Pharmacology, UCSF, Box 0450, San Francisco, CA 94143 0450, USA
Nucleic Acids Res 29:346-9. 2001..The NucleaRDB was started recently as an application of the concept for the generalization of this technology. The GPCRDB is available via the WWW at http://www.gpcr.org/7tm/ and the NucleaRDB at http://www.receptors.org/NR/...
- Automated extraction of mutation data from the literature: application of MuteXt to G protein-coupled receptors and nuclear hormone receptorsFlorence Horn
Department of Cellular and Molecular Pharmacology, University of California of San Francisco, 94143, USA
Bioinformatics 20:557-68. 2004..3% of the GPCR point mutations with a specificity of 87.9%, and 64.5% of the NR point mutations with a specificity of 85.8%. MuteXt routinely analyzes 100 electronic articles in approximately 1 h...
- Automatic extraction of protein point mutations using a graph bigram associationLawrence C Lee
Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California, United States of America
PLoS Comput Biol 3:e16. 2007..73. We believe the graph bigram search metric to be a significant improvement over previous search metrics for point mutation extraction and to be applicable to text-mining application requiring the association of words...
- GPCRDB information system for G protein-coupled receptorsFlorence Horn
Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, California, USA
Nucleic Acids Res 31:294-7. 2003..The GPCRDB is updated automatically once every 4-5 months and is freely accessible at http://www.gpcr.org/7tm/...
- Phosphorylation and intramolecular stabilization of the ligand binding domain in the nuclear receptor steroidogenic factor 1Marion Desclozeaux
Departments of Physiology Cellular and Molecular Pharmacology Biochemistry and Biophysics University of California San Francisco, San Francisco, California 94143 0444, USA
Mol Cell Biol 22:7193-203. 2002....
- NRSAS: Nuclear Receptor Structure Analysis ServersEmmanuel Bettler
CMBI KUN, PO Box 9010, 6500 GL Nijmegen, The Netherlands
Nucleic Acids Res 31:3400-3. 2003..The Nuclear Receptor Structure Analysis Servers (NRSAS) are freely accessible at http://www.cmbi.kun.nl/NR/servers/html/ and in-house copies can be obtained upon request...
- A family-based approach reveals the function of residues in the nuclear receptor ligand-binding domainSimon Folkertsma
CMBI, University of Nijmegen, PO Box 9010, 6500 GL Nijmegen, The Netherlands
J Mol Biol 341:321-35. 2004..The results shed light on the nuclear receptor family that is involved in processes ranging from cancer to infertility, and that is one of the more important targets in the pharmaceutical industry...
- GRIS: glycoprotein-hormone receptor information systemJoost Van Durme
Institut de Recherche Interdisciplinaire en Biologie Humaine et Moleculaire, Universite Libre de Bruxelles, Campus Erasme, Route de Lennik 808, B 1070 Brussels, Belgium
Mol Endocrinol 20:2247-55. 2006..Users can upload new mutations. GRIS is freely accessible at http://gris.ulb.ac.be/...