WILLIAM HORAN

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Impaired neural response to internal but not external feedback in schizophrenia
    W P Horan
    VA Greater Los Angeles Healthcare System, University of California, Los Angeles, CA 90073, USA
    Psychol Med 42:1637-47. 2012
  2. pmc Social cognition in schizophrenia, Part 2: 12-month stability and prediction of functional outcome in first-episode patients
    William P Horan
    Department of Psychiatry, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA, USA
    Schizophr Bull 38:865-72. 2012
  3. pmc Intact motivated attention in schizophrenia: evidence from event-related potentials
    William P Horan
    VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, United States
    Schizophr Res 135:95-9. 2012
  4. pmc Social cognitive skills training in schizophrenia: an initial efficacy study of stabilized outpatients
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Schizophr Res 107:47-54. 2009
  5. pmc Disturbances in the spontaneous attribution of social meaning in schizophrenia
    W P Horan
    University of California, Los Angeles, CA 90095 6968, USA
    Psychol Med 39:635-43. 2009
  6. pmc Verbal working memory impairments in individuals with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at University of California Los Angeles, Los Angeles, California 90095 6968, USA
    Schizophr Res 103:218-28. 2008
  7. pmc Affective traits in schizophrenia and schizotypy
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90095, USA
    Schizophr Bull 34:856-74. 2008
  8. ncbi request reprint Does anhedonia in schizophrenia reflect faulty memory for subjectively experienced emotions?
    William P Horan
    Aftercare Research Program, Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, 90095, USA
    J Abnorm Psychol 115:496-508. 2006
  9. pmc The validity of Psychosis Proneness Scales as vulnerability indicators in recent-onset schizophrenia patients
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, USA
    Schizophr Res 100:224-36. 2008
  10. ncbi request reprint Stress and coping responses to a natural disaster in people with schizophrenia
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA 90095, USA
    Psychiatry Res 151:77-86. 2007

Detail Information

Publications41

  1. pmc Impaired neural response to internal but not external feedback in schizophrenia
    W P Horan
    VA Greater Los Angeles Healthcare System, University of California, Los Angeles, CA 90073, USA
    Psychol Med 42:1637-47. 2012
    ..Although individuals with schizophrenia consistently demonstrate a diminished ERN, the integrity of the FN has received minimal consideration...
  2. pmc Social cognition in schizophrenia, Part 2: 12-month stability and prediction of functional outcome in first-episode patients
    William P Horan
    Department of Psychiatry, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA, USA
    Schizophr Bull 38:865-72. 2012
    ..Social cognitive impairments may serve as useful vulnerability indicators and early clinical intervention targets...
  3. pmc Intact motivated attention in schizophrenia: evidence from event-related potentials
    William P Horan
    VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, United States
    Schizophr Res 135:95-9. 2012
    ..Emotional stimuli captured attentional resources in people with schizophrenia even when the emotional stimuli were task-irrelevant, suggesting intact motivated attention at the level of early electrophysiological responding...
  4. pmc Social cognitive skills training in schizophrenia: an initial efficacy study of stabilized outpatients
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Schizophr Res 107:47-54. 2009
    ....
  5. pmc Disturbances in the spontaneous attribution of social meaning in schizophrenia
    W P Horan
    University of California, Los Angeles, CA 90095 6968, USA
    Psychol Med 39:635-43. 2009
    ..However, these tasks are often developmentally inappropriate, make large demands on verbal abilities and explicit problem-solving skills, and involve after-the-fact reflection as opposed to spontaneous mentalizing...
  6. pmc Verbal working memory impairments in individuals with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at University of California Los Angeles, Los Angeles, California 90095 6968, USA
    Schizophr Res 103:218-28. 2008
    ....
  7. pmc Affective traits in schizophrenia and schizotypy
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90095, USA
    Schizophr Bull 34:856-74. 2008
    ..Results are discussed in terms of their implications for treatment, etiological models, and future research to advance the study of affective traits in schizophrenia and schizotypy...
  8. ncbi request reprint Does anhedonia in schizophrenia reflect faulty memory for subjectively experienced emotions?
    William P Horan
    Aftercare Research Program, Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, 90095, USA
    J Abnorm Psychol 115:496-508. 2006
    ..In-the-moment pleasure and short-term retention for emotional experiences thus appear to be relatively intact in schizophrenia. Alternative explanations for the hedonic deficit in this disorder are discussed...
  9. pmc The validity of Psychosis Proneness Scales as vulnerability indicators in recent-onset schizophrenia patients
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, USA
    Schizophr Res 100:224-36. 2008
    ..The longitudinal characteristics of these scales in people who are actually diagnosed with schizophrenia provide key evidence for the validity of three commonly used psychometric indicators of vulnerability to psychosis...
  10. ncbi request reprint Stress and coping responses to a natural disaster in people with schizophrenia
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA 90095, USA
    Psychiatry Res 151:77-86. 2007
    ..Results support the validity of prior reports of altered responses to stressful life events in schizophrenia and demonstrate the clinical relevance of individual differences in coping among affected individuals...
  11. pmc Anhedonia in schizophrenia: a review of assessment strategies
    William P Horan
    University of California, Los Angeles, USA
    Schizophr Bull 32:259-73. 2006
    ..Current efforts to define more precisely the nature of the hedonic deficit in schizophrenia are discussed, and recommendations for optimal assessment of anhedonia in clinical trials of novel treatments for negative symptoms are provided...
  12. ncbi request reprint Stability and clinical correlates of personality characteristics in recent-onset schizophrenia
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles 90095 6968, CA, USA
    Psychol Med 35:995-1005. 2005
    ..While several personality characteristics are implicated in the etiology and phenotypic expression of schizophrenia, little is known about their trait status or clinical correlates during the early course of this disorder...
  13. pmc Further support for the role of dysfunctional attitudes in models of real-world functioning in schizophrenia
    William P Horan
    VA Greater Los Angeles Healthcare System, University of California, Department of Psychiatry and Biobehavioral Sciences, Los Angeles, CA 90073, USA
    J Psychiatr Res 44:499-505. 2010
    ..These findings support the value of dysfunctional attitudes for understanding the determinants of outcome in schizophrenia and suggest that therapeutic interventions targeting these attitudes may facilitate functional recovery...
  14. ncbi request reprint Stressful life events in recent-onset schizophrenia: reduced frequencies and altered subjective appraisals
    William P Horan
    University of California, Los Angeles, CA 90095 9698, USA
    Schizophr Res 75:363-74. 2005
    ..Results are discussed in terms of their implications for understanding susceptibility to stress during the early course of schizophrenia...
  15. pmc Development and psychometric validation of the Clinical Assessment Interview for Negative Symptoms (CAINS)
    William P Horan
    VA Greater Los Angeles Healthcare System, University of California, Los Angeles, California, United States
    Schizophr Res 132:140-5. 2011
    ..Results guided item modification or deletion, and the reliability and validity of the revised, shorter version of the CAINS is in the final phase of development within the CANSAS project...
  16. ncbi request reprint The psychometric detection of schizotypy: do putative schizotypy indicators identify the same latent class?
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA 90025, USA
    J Abnorm Psychol 113:339-57. 2004
    ..Measures commonly thought to tap the same latent class, conjectured to be schizotypy, do not share this property...
  17. doi request reprint Efficacy and specificity of social cognitive skills training for outpatients with psychotic disorders
    William P Horan
    Department of Veterans Affairs VISN 22 Mental Illness Research, Education, and Clinical Center, Los Angeles, CA, USA
    J Psychiatr Res 45:1113-22. 2011
    ..Findings provide guidance for continued efforts to maximize the benefits of social cognitive interventions...
  18. ncbi request reprint Neurocognitive, social, and emotional dysfunction in deficit syndrome schizophrenia
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, 300 UCLA Medical Plaza, Rm 2255, Los Angeles, CA 90024 6968, USA
    Schizophr Res 65:125-37. 2003
    ....
  19. pmc Impaired implicit learning in schizophrenia
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, USA
    Neuropsychology 22:606-17. 2008
    ..Discussion focuses on possible explanations for schizophrenia patients' poor probabilistic classification task performance...
  20. pmc Electrophysiological correlates of emotional responding in schizophrenia
    William P Horan
    Department of Psychiatry, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
    J Abnorm Psychol 119:18-30. 2010
    ..However, they showed a disruption in a later component associated with sustained attentional processing of emotional stimuli...
  21. ncbi request reprint Social anhedonia and schizotypy: the contribution of individual differences in affective traits, stress, and coping
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, USA
    Psychiatry Res 149:147-56. 2007
    ..Longitudinal studies are required to determine whether these individual differences potentiate clinical outcomes among social anhedonics...
  22. ncbi request reprint Emotional responses to psychosocial stress in schizophrenia: the role of individual differences in affective traits and coping
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, 300 Medical Plaza, Rm 2255, 90024 6968, Los Angeles, CA, USA
    Schizophr Res 60:271-83. 2003
    ....
  23. ncbi request reprint A retrospective study of premorbid ability and aging differences in cognitive clusters of schizophrenia
    William P Horan
    University of California, Los Angeles, CA, USA
    Psychiatry Res 118:209-21. 2003
    ..Results provide further support for the validity of these subgroups and encourage continued efforts to identify cognitively based candidate schizophrenia subtypes...
  24. pmc The Consortium on the Genetics of Schizophrenia: neurocognitive endophenotypes
    Raquel E Gur
    Neuropsychiatry Section, Department of Psychiatry, University of Pennsylvania, 10 Gates, 3400 Spruce St, Philadelphia, PA 19104, USA
    Schizophr Bull 33:49-68. 2007
    ....
  25. pmc Mismatch negativity, social cognition, and functioning in schizophrenia patients
    Jonathan K Wynn
    Mental Illness Research, Education and Clinical Center, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California, USA
    Biol Psychiatry 67:940-7. 2010
    ..Prior studies found associations between mismatch negativity (MMN), an event-related potential response indexing early auditory processing, and functioning in schizophrenia patients...
  26. pmc Do patients with schizophrenia benefit from a self-referential memory bias?
    Philippe Olivier Harvey
    Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles 90073 1003, United States
    Schizophr Res 127:171-7. 2011
    ..It is not known whether schizophrenia patients benefit from such a memory boost for self-referenced information...
  27. ncbi request reprint Do the siblings of schizophrenia patients demonstrate affect perception deficits?
    Kimmy S Kee
    University of California, Los Angeles, CA, USA
    Schizophr Res 67:87-94. 2004
    ..These findings demonstrate that subtle deficits in affect perception are detectable in the unaffected siblings of schizophrenia patients when multiple measures of different types of affect perception abilities are used in combination...
  28. pmc Psychosocial treatments to promote functional recovery in schizophrenia
    Robert S Kern
    Veterans Affairs Greater Los Angeles Healthcare System MIRECC 210 A, Building 210, Room 116, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA
    Schizophr Bull 35:347-61. 2009
    ..Overall, these treatments provide a range of promising approaches to helping patients achieve better outcomes far beyond symptom stabilization...
  29. pmc Impaired anticipatory event-related potentials in schizophrenia
    Jonathan K Wynn
    VA Greater Los Angeles Healthcare System, University of California, Los Angeles, USA
    Int J Psychophysiol 77:141-9. 2010
    ..Schizophrenia patients demonstrate diminished motor- and non-motor-related anticipatory processing, which may have wide-ranging adverse functional consequences...
  30. doi request reprint Emotional intelligence in schizophrenia
    Kimmy S Kee
    Psychology Program, California State University Channel Islands, USA
    Schizophr Res 107:61-8. 2009
    ..D., Salovey, P., Caruso, D.R., 2002. Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT): User's Manual. Multi-Health Systems, Inc., Toronto, Ontario)...
  31. ncbi request reprint The timing of negative symptom exacerbations in relationship to positive symptom exacerbations in the early course of schizophrenia
    Joseph Ventura
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles 300 UCLA Medical Plaza, Room 2243, Los Angeles, CA 90095 6968, USA
    Schizophr Res 69:333-42. 2004
    ..Results suggest that the timing of some negative symptom exacerbations is linked to that of positive symptom exacerbations during the early course of schizophrenia...
  32. pmc Using event related potentials to explore stages of facial affect recognition deficits in schizophrenia
    Jonathan K Wynn
    VA Greater Los Angeles Healthcare System, MIRECC, Building 210, Los Angeles, CA 90073, USA
    Schizophr Bull 34:679-87. 2008
    ..Our results imply that abnormalities in the later stage of feature decoding could potentially underlie emotion identification deficits in schizophrenia...
  33. ncbi request reprint An analysis of categorical perception of facial emotion in schizophrenia
    Kimmy S Kee
    California State University Channel Islands, United States
    Schizophr Res 87:228-37. 2006
    ....
  34. ncbi request reprint Do recent-onset schizophrenia patients experience a "social network crisis"?
    William P Horan
    Department of Psychiatry and Biobehavioral Sciences at the University of California, 300 Medical Plaza, Los Angeles, CA 90095 6968, USA
    Psychiatry 69:115-29. 2006
    ..Instead, results suggest that functionally relevant social network disturbances often exist by the time of first hospitalization in schizophrenia...
  35. ncbi request reprint Neurocognitive and social cognitive correlates of formal thought disorder in schizophrenia patients
    Kenneth L Subotnik
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, 90095 6968, USA
    Schizophr Res 85:84-95. 2006
    ..This pattern of findings is consistent with the view that neurocognitive and, possibly, social cognitive deficits underlie these two aspects of formal thinking disturbance in schizophrenia...
  36. ncbi request reprint Schizophrenia patients demonstrate a distinctive pattern of decision-making impairment on the Iowa Gambling Task
    Brett Shurman
    University of California Los Angeles, Neuropsychiatric Institute 300 UCLA Medical Plaza, Los Angeles, CA 90095 6968, USA
    Schizophr Res 72:215-24. 2005
    ..Results suggest that individuals with schizophrenia display a pattern of compromised decision-making that is somewhat distinct from that found in OFC lesion patients and that may be linked to certain clinical symptoms...
  37. doi request reprint Is there an association between advanced paternal age and endophenotype deficit levels in schizophrenia?
    Debby Tsuang
    VISN 20 Geriatric Research, Education, and Clinical Center, VA Puget Sound Health Care System, Seattle, Washington, United States of America Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, United States of America
    PLoS ONE 9:e88379. 2014
    ..These findings suggest that factors other than advanced paternal age at birth may account for endophenotypic deficit levels in schizophrenia. ..
  38. pmc Anhedonia in schizophrenia: distinctions between anticipatory and consummatory pleasure
    David E Gard
    Department of Psychology, San Francisco State University, 1600 Holloway Avenue, San Francisco, CA, 94132 4168, United States
    Schizophr Res 93:253-60. 2007
    ..In addition, anticipatory pleasure was related to clinical ratings of anhedonia and functional outcome. Clinical and research implications of these findings are discussed...
  39. ncbi request reprint The expression and experience of emotion in schizophrenia: a study of social interactions
    Minu A Aghevli
    Department of Psychology, University of Maryland, College Park, MD 20742, USA
    Psychiatry Res 119:261-70. 2003
    ..These results extend prior findings of an expression/experience disjunction in schizophrenia to a social domain. Implications for understanding social dysfunction in schizophrenia and directions for future study are discussed...
  40. ncbi request reprint Correlations between age and higher cognitive function in schizophrenia subgroups
    William P Horan
    Schizophr Res 61:325-6. 2003
  41. ncbi request reprint Examining the latent structure of negative symptoms: is there a distinct subtype of negative symptom schizophrenia?
    Jack J Blanchard
    Department of Psychology, University of Maryland, College Park, MD 20742 4411, USA
    Schizophr Res 77:151-65. 2005
    ..Further research is required to replicate the present taxonic findings and to examine characteristics (including possible etiological factors) associated with this negative symptom taxon...

Research Grants3

  1. Electrophysiological Correlates of Anhedonia in Schizophrenia
    WILLIAM HORAN; Fiscal Year: 2007
    ....
  2. 3/4 Collaboration to Advance Negative Symptom Assessment in Schizophrenia
    William P Horan; Fiscal Year: 2010
    ..This state-of-the art instrument will play a central role in the NIMH initiative to stimulate the development of new treatments aimed at reducing the disability associated with negative symptoms. ..