C J Hopfer

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. ncbi Common genetic and environmental vulnerability for alcohol and tobacco use in a volunteer sample of older female twins
    C J Hopfer
    University of Colorado Health Sciences Center, Denver 80262, USA
    J Stud Alcohol 62:717-23. 2001
  2. pmc A genome-wide scan for loci influencing adolescent cannabis dependence symptoms: evidence for linkage on chromosomes 3 and 9
    Christian J Hopfer
    Division of Substance Dependence, University of Colorado School of Medicine, 4200 East Ninth Avenue, Denver, CO 80262, USA
    Drug Alcohol Depend 89:34-41. 2007
  3. ncbi Club drug use among youths in treatment for substance abuse
    Christian Hopfer
    Department of Psychiatry, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Am J Addict 15:94-9. 2006
  4. ncbi Genetic influences on quantity of alcohol consumed by adolescents and young adults
    Christian J Hopfer
    Department of Psychiatry, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Box C 268 35, Denver, CO 80262, USA
    Drug Alcohol Depend 78:187-93. 2005
  5. pmc Cannabis receptor haplotype associated with fewer cannabis dependence symptoms in adolescents
    Christian J Hopfer
    Department of Psychiatry, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Am J Med Genet B Neuropsychiatr Genet 141:895-901. 2006
  6. ncbi Review of twin and adoption studies of adolescent substance use
    Christian J Hopfer
    Division of Substance Dependence, Department of Psychiatry, University of Colorado Health Sciences Center, Denver, USA
    J Am Acad Child Adolesc Psychiatry 42:710-9. 2003
  7. ncbi Family transmission of marijuana use, abuse, and dependence
    Christian J Hopfer
    University of Colorado Health Sciences Center, Denver 80262, USA
    J Am Acad Child Adolesc Psychiatry 42:834-41. 2003
  8. ncbi Treating adolescent heroin use
    Christian J Hopfer
    Division of Substance Dependence, University of Colorado School of Medicine, UC Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
    J Am Acad Child Adolesc Psychiatry 42:609-11. 2003
  9. ncbi Adolescent heroin use: a review of the descriptive and treatment literature
    Christian J Hopfer
    Division of Substance Dependence, University of Colorado School of Medicine, Denver, CO 80262, USA
    J Subst Abuse Treat 23:231-37. 2002
  10. ncbi The human protein kinase C gamma gene (PRKCG) as a susceptibility locus for behavioral disinhibition
    Isabel R Schlaepfer
    Institute for Behavioral Genetics, University of Colorado, Boulder, USA, and Department of Integrative Physiology, University of Colorado, Boulder, CO 80309, USA
    Addict Biol 12:200-9. 2007

Detail Information

Publications26

  1. ncbi Common genetic and environmental vulnerability for alcohol and tobacco use in a volunteer sample of older female twins
    C J Hopfer
    University of Colorado Health Sciences Center, Denver 80262, USA
    J Stud Alcohol 62:717-23. 2001
    ..We report patterns of genetic and environmental correlations for alcohol and tobacco use in a volunteer sample of older, white, female twins using three different levels of severity for alcohol use and smoking...
  2. pmc A genome-wide scan for loci influencing adolescent cannabis dependence symptoms: evidence for linkage on chromosomes 3 and 9
    Christian J Hopfer
    Division of Substance Dependence, University of Colorado School of Medicine, 4200 East Ninth Avenue, Denver, CO 80262, USA
    Drug Alcohol Depend 89:34-41. 2007
    ..Genetic risk factors account for part of the variation in the development of cannabis dependence symptoms; however, no linkage studies have been performed for cannabis dependence symptoms. This study aimed to identify such loci...
  3. ncbi Club drug use among youths in treatment for substance abuse
    Christian Hopfer
    Department of Psychiatry, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Am J Addict 15:94-9. 2006
    ..01). Youths reported using club drugs frequently outside of rave settings. Club drug use is common among youths in treatment for substance abuse and has spread beyond the rave culture...
  4. ncbi Genetic influences on quantity of alcohol consumed by adolescents and young adults
    Christian J Hopfer
    Department of Psychiatry, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Box C 268 35, Denver, CO 80262, USA
    Drug Alcohol Depend 78:187-93. 2005
    ..To examine genetic and environmental influences on drinking in a nationally representative study of genetically informative adolescents followed into young adulthood...
  5. pmc Cannabis receptor haplotype associated with fewer cannabis dependence symptoms in adolescents
    Christian J Hopfer
    Department of Psychiatry, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Am J Med Genet B Neuropsychiatr Genet 141:895-901. 2006
    ..Our findings provide evidence suggesting that a common CNR1 haplotype is associated with developing fewer cannabis dependence symptoms among adolescents who have experimented with cannabis...
  6. ncbi Review of twin and adoption studies of adolescent substance use
    Christian J Hopfer
    Division of Substance Dependence, Department of Psychiatry, University of Colorado Health Sciences Center, Denver, USA
    J Am Acad Child Adolesc Psychiatry 42:710-9. 2003
    ..To review studies of adolescent substance use and abuse with genetically informative designs...
  7. ncbi Family transmission of marijuana use, abuse, and dependence
    Christian J Hopfer
    University of Colorado Health Sciences Center, Denver 80262, USA
    J Am Acad Child Adolesc Psychiatry 42:834-41. 2003
    ..To examine the familial aggregation of marijuana use, abuse, and dependence...
  8. ncbi Treating adolescent heroin use
    Christian J Hopfer
    Division of Substance Dependence, University of Colorado School of Medicine, UC Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
    J Am Acad Child Adolesc Psychiatry 42:609-11. 2003
  9. ncbi Adolescent heroin use: a review of the descriptive and treatment literature
    Christian J Hopfer
    Division of Substance Dependence, University of Colorado School of Medicine, Denver, CO 80262, USA
    J Subst Abuse Treat 23:231-37. 2002
    ..Length of time in treatment, regardless of modality, was the best predictor of outcome. The rise of heroin use among adolescents and young adults calls for descriptive studies as well as controlled treatment studies...
  10. ncbi The human protein kinase C gamma gene (PRKCG) as a susceptibility locus for behavioral disinhibition
    Isabel R Schlaepfer
    Institute for Behavioral Genetics, University of Colorado, Boulder, USA, and Department of Integrative Physiology, University of Colorado, Boulder, CO 80309, USA
    Addict Biol 12:200-9. 2007
    ..This study provides the first exploration of the PRKCG gene and its association with behavioral disinhibition and warrants further study in other larger population samples...
  11. pmc Item response theory analysis of DSM-IV cannabis abuse and dependence criteria in adolescents
    Christie A Hartman
    School of Medicine at the University of Colorado Health Sciences Center, 4200 East 9th Avenue, Denver, CO 80262, USA
    J Am Acad Child Adolesc Psychiatry 47:165-73. 2008
    ..different levels of severity of substance involvement, to what degree do each of the 11 abuse and dependence criteria assess adolescent cannabis problems, and do the DSM-IV items function similarly across different adolescent populations?..
  12. ncbi Test of association between TaqIA A1 allele and alcohol use disorder phenotypes in a sample of adolescent patients with serious substance and behavioral problems
    Joseph T Sakai
    Department of Psychiatry, Division of Substance Dependence, University of Colorado School of Medicine, Denver, CO 80262, USA
    Drug Alcohol Depend 88:130-7. 2007
    ....
  13. ncbi Case-control and within-family tests for association between 5HTTLPR and conduct problems in a longitudinal adolescent sample
    Joseph T Sakai
    Division of Substance Dependence, Department of Psychiatry, University of Colorado School of Medicine, Denver CO 80262, USA
    Psychiatr Genet 17:207-14. 2007
    ..Using a large general population sample, we sought to test for an association between 5HTTLPR and conduct problems, and to explore for a possible 5HTTLPR by maltreatment interaction...
  14. ncbi Mate similarity for substance dependence and antisocial personality disorder symptoms among parents of patients and controls
    J T Sakai
    Division of Substance Dependence, Department of Psychiatry, University of Colorado School of Medicine, 4200 E Ninth Avenue, C268 35, Denver, CO 80262, USA
    Drug Alcohol Depend 75:165-75. 2004
    ..Substance dependence (SD) and antisocial personality disorder (ASPD) are highly comorbid and aggregate in families. Mating assortment may be an important process contributing to this familial aggregation...
  15. ncbi The family transmission of adolescent alcohol abuse and dependence
    Christie A Hartman
    University of Colorado Health Sciences Center, Division of Substance Dependence, 4200 East 9th Avenue, Box C 268 35, Denver, Colorado 80262, USA
    J Stud Alcohol 67:657-64. 2006
    ..This study examines the familial transmission of alcohol abuse and dependence to adolescents...
  16. ncbi Lesbian, gay, and bisexual homeless youth: an eight-city public health perspective
    James M Van Leeuwen
    Urban Peak, Denver, CO, USA
    Child Welfare 85:151-70. 2006
    ....
  17. pmc The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults
    Isabel R Schlaepfer
    Institute for Behavioral Genetics, Department of Integrative Physiology, University of Colorado, Boulder, CO 80309, USA
    Biol Psychiatry 63:1039-46. 2008
    ..Significant results were then replicated in a separate adult population-representative sample...
  18. ncbi The neuronal nicotinic receptor subunit genes (CHRNA6 and CHRNB3) are associated with subjective responses to tobacco
    Joanna S Zeiger
    Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309, USA
    Hum Mol Genet 17:724-34. 2008
    ..These results indicate that early subjective response to nicotine may be a valuable endophenotype for genetic studies aimed at uncovering genes contributing to nicotine use and addiction...
  19. ncbi Monoamine oxidase A (MAOA) and antisocial behaviors in the presence of childhood and adolescent maltreatment
    Brett C Haberstick
    Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309 0447, USA
    Am J Med Genet B Neuropsychiatr Genet 135:59-64. 2005
    ..There was, however, a non-significant trend in the predicted direction. Additional studies will be needed before firm conclusions can be drawn about this hypothesized genotype-environment interaction...
  20. ncbi Relationship between adolescent marijuana use and young adult illicit drug use
    Jeffrey M Lessem
    Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309 0447, USA
    Behav Genet 36:498-506. 2006
    ..Shared environmental factors mediated much of the relationship between adolescent marijuana use and young adult drug use. The association remained, however, even when controlling for familial environmental and other measured factors...
  21. pmc Between- and within-family association test of the dopamine receptor D2 TaqIA polymorphism and alcohol abuse and dependence in a general population sample of adults
    Brett C Haberstick
    Institute for Behavioral Genetics, University of Colorado at Boulder, Boulder, CO 80309 0447, USA
    J Stud Alcohol Drugs 68:362-70. 2007
    ..The mixed results of association between the DRD2 TaqIA polymorphism and alcohol-use disorders may be the result of differences in sample size, phenotype definition, heterogeneity of the samples, and genetic admixture...
  22. ncbi Association of the neuronal nicotinic receptor beta2 subunit gene (CHRNB2) with subjective responses to alcohol and nicotine
    Marissa A Ehringer
    Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309, USA
    Am J Med Genet B Neuropsychiatr Genet 144:596-604. 2007
    ..This study provides the first evidence for association between the CHRNB2 gene and nicotine- and alcohol-related phenotypes, and suggests that polymorphisms in CHRNB2 may be important in mediating early responses to nicotine and alcohol...
  23. pmc Association of candidate genes with antisocial drug dependence in adolescents
    Robin P Corley
    Institute for Behavioral Genetics, University of Colorado, 447 UCB, Boulder, CO 80309, USA
    Drug Alcohol Depend 96:90-8. 2008
    ..The custom-designed SNP chip served as an effective and flexible platform for rapid interrogation of a large number of plausible candidate genes...
  24. ncbi College attendance and its effect on drinking behaviors in a longitudinal study of adolescents
    David S Timberlake
    Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado, USA
    Alcohol Clin Exp Res 31:1020-30. 2007
    ..We first tested for changes in alcohol consumption in adolescents who did and did not subsequently attend college, and then tested for variation of the genetic and environmental determinants of drinking in these 2 groups...
  25. ncbi Genes, time to first cigarette and nicotine dependence in a general population sample of young adults
    Brett C Haberstick
    Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309, USA
    Addiction 102:655-65. 2007
    ..To examine variation in nicotine dependence scores and covariation between different dependence symptoms...
  26. ncbi Progression from marijuana use to daily smoking and nicotine dependence in a national sample of U.S. adolescents
    David S Timberlake
    Institute for Behavioral Genetics, University of Colorado, Campus Box 447, Boulder, CO 80303, USA
    Drug Alcohol Depend 88:272-81. 2007
    ....