Harriet W Hopf
Affiliation: University of Utah
- Hyperoxia and infectionHarriet W Hopf
Department of Anesthesiology, University of Utah, Room 3C444, 30 N 1900 East, Salt Lake City, UT 84132, USA
Best Pract Res Clin Anaesthesiol 22:553-69. 2008..This article will review the basic science underlying these observations, along with the clinical data that support the use of hyperoxia in preventing and treating infections...
- Is it time to retire high-concentration nitrous oxide?Harriet W Hopf
Anesthesiology 107:200-1. 2007
- Wounds: an overview of the role of oxygenHarriet W Hopf
Department of Anesthesiology, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
Antioxid Redox Signal 9:1183-92. 2007..Our understanding of the role of oxygen in wound healing has been fueled by tissue oximetry. Advances in technology will lead to further advances in the management of patients with wounds...
- Empiric evidence for a genetic contribution to predisposition to surgical site infectionJames P Lee
Department of Anesthesiology, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
Wound Repair Regen 21:211-5. 2013..019). The RR for third-degree relatives of cases was significantly elevated (1.62, p = 0.029). The significant excess relatedness and the significantly elevated RR to distant relatives support a genetic predisposition to acquiring SSI...
- High intraoperative inspired oxygen does not increase postoperative supplemental oxygen requirementsNatalie Mackintosh
Department of Anesthesiology, University of Utah School of Medicine, Salt Lake City, UT, USA
Anesthesiology 117:271-9. 2012..3 versus more than 0.9 with and without positive end-expiratory pressure on the primary outcome of postoperative supplemental oxygen requirements in patients undergoing lower risk surgery...
- Guidelines for the treatment of arterial insufficiency ulcersHarriet W Hopf
University of Utah, Salt Lake City, UT, USA
Wound Repair Regen 14:693-710. 2006
- Measuring oxygen in woundsHarriet W Hopf
Department of Surgery, UCSF, Wound Healing Laboratory, San Francisco, California 94143 0522, USA
Methods Enzymol 381:539-64. 2004
- Development of subcutaneous wound oxygen measurement in humans: contributions of Thomas K Hunt, MDHarriet W Hopf
Department of Anesthesia and Perioperative Care, University of California, San Francisco, California 94143 0648, USA
Wound Repair Regen 11:424-30. 2003..All these observations required tissue oxygen measurement, and, in particular, translation of basic scientific observations to clinical research required a method of measuring wound oxygen tension in humans...
- Methods of measuring oxygen in woundsHarriet W Hopf
Department of Anesthesia and Perioperative Care, Department of Surgery, University of California, San Francisco, CA, USA
Methods Mol Med 78:389-416. 2003
- How heel oxygenation changes under pressureVivian K Wong
School of Nursing, San Jose State University, San Jose, California 95192 0057, USA
Wound Repair Regen 15:786-94. 2007..Further work is needed to understand why this short period of external pressure results in decreased oxygenation and why oxygen tension does not return to baseline when pressure is removed...
- Using physiology to improve surgical wound outcomesChristiane Ueno
University of California, San Francisco, Wound Healing Laboratory, Departments of Anesthesia and Perioperative Care and Surgery, San Francisco, Calif 94143 0648, USA
Plast Reconstr Surg 117:59S-71S. 2006..This article reviews how knowledge of and attention to physiology can improve quality of care in both acute and chronic wounds...
- Perflubron emulsion increases subcutaneous tissue oxygen tension in ratsNoah A Rosen
Department of Surgery, Boston University Medical Center, Boston, Massachusetts, USA
Wound Repair Regen 14:55-60. 2006..0 vol%. These findings agree with those results analytically predicted based on the oxygen solubility of the perflubron emulsion...
- Hyperoxia and angiogenesisHarriet W Hopf
Wound Healing Research Laboratory, Department of Anesthesia and Perioperative Care, University of California, San Francisco, California 94143, USA
Wound Repair Regen 13:558-64. 2005..We conclude that angiogenesis is proportional to ambient pO(2) over a wide range. This confirms the clinical impression that angiogenesis requires oxygen. Intermittent oxygen exposure can satisfy the need for oxygen in ischemic tissue...
- Hyperoxia improves microvascular perfusion in a murine wound modelAhmad Y Sheikh
Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
Wound Repair Regen 13:303-8. 2005..05). Laser Doppler imaging was able to detect and quantify the increase in wound bed perfusion resulting from intermittent HBO treatments and shows promise as a noninvasive measure of angiogenesis and wound healing...
- Facilitating positive outcomes in older adults with woundsNancy A Stotts
School of Nursing, University of California San Francisco, 2 Koret Way, No 631, San Francisco, CA 94143, USA
Nurs Clin North Am 40:267-79. 2005..These seemingly basic issues raise questions for clinicians as we strive to provide evidence-based care to this ever-increasing population of older Americans...
- Acute isovolemic anemia impairs central processing as determined by P300 latencyRichard B Weiskopf
Departments of Anesthesia and Physiology, Cardiovascular Research Institute, University of California, San Francisco, 94143 0648, USA
Clin Neurophysiol 116:1028-32. 2005..Acute anemia slows the responses to clinical tests of cognitive function. We tested the hypothesis that these slowed responses during acute severe isovolemic anemia in healthy unmedicated humans result from impaired central processing...
- Supplemental oxygen and risk of surgical site infectionHarriet W Hopf
JAMA 291:1956; author reply 1958-9. 2004
- Paradigm of the injury-repair continuum during critical illnessLudwig H Lin
Department of Anesthesia and Perioperative Care, University of California San Francisco, USA
Crit Care Med 31:S493-5. 2003..To define injury and repair in the context of critical illness...
- The link between tissue oxygen and hydration in nursing home residents with pressure ulcers: preliminary dataNancy A Stotts
Department of Physiological Nursing, University of California San Francisco, USA
J Wound Ostomy Continence Nurs 30:184-90. 2003..Further research in this area is warranted...
- Accuracy of a polarographic electrode at high oxygen concentrationsMark D Rollins
Bioengineering Graduate Group, University of California, San Francisco, CA, USA
Adv Exp Med Biol 510:169-73. 2003
- Noninvasive assessment of wound-healing angiogenesis with contrast-enhanced MRIThomas H Helbich
Center for Pharmaceutical and Molecular Imaging, Department of Radiology, University of California, San Francisco 94143 0628, USA
Acad Radiol 9:S145-7. 2002
- Oxygen reverses deficits of cognitive function and memory and increased heart rate induced by acute severe isovolemic anemiaRichard B Weiskopf
Department of Anesthesia, University of California, San Francisco, California 94143 0648, USA
Anesthesiology 96:871-7. 2002....