Research Topics
| Harriet W HopfSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Hyperoxia and angiogenesisHarriet W Hopf
Wound Healing Research Laboratory, Department of Anesthesia and Perioperative Care, University of California, San Francisco, California 94143, USA
Wound Repair Regen 13:558-64. 2005..We conclude that angiogenesis is proportional to ambient pO(2) over a wide range. This confirms the clinical impression that angiogenesis requires oxygen. Intermittent oxygen exposure can satisfy the need for oxygen in ischemic tissue...
Measuring oxygen in woundsHarriet W Hopf
Department of Surgery, UCSF, Wound Healing Laboratory, San Francisco, California 94143-0522, USA
Methods Enzymol 381:539-64. 2004
High oxygen partial pressure decreases anemia-induced heart rate increase equivalent to transfusionJohn R Feiner
Department of Anesthesia and Perioperative Care, University of California, San Francisco, California 94143 0648, USA
Anesthesiology 115:492-8. 2011..The authors sought to directly compare the effect of high inspired oxygen fraction versus transfusion of erythrocytes on the anemia-induced increased heart rate (HR) in humans undergoing experimental acute isovolemic anemia...
Quantitative tissue oxygen measurement in multiple organs using 19F MRI in a rat modelSiyuan Liu
Department of Radiology and Biomedical Imaging, University of California, San Francisco, California 94143 0464, USA
Magn Reson Med 66:1722-30. 2011..001). This study demonstrates that (19) F MRI of hexafluorobenzene offers a feasible tool to measure regional ptO2 in vivo, and that hyperoxia significantly increases ptO2 of multiple organs in a rat model...
Noninvasive assessment of wound-healing angiogenesis with contrast-enhanced MRIThomas H Helbich
Center for Pharmaceutical and Molecular Imaging, Department of Radiology, University of California, San Francisco 94143-0628, USA
Acad Radiol 9:S145-7. 2002
Methods of measuring oxygen in woundsHarriet W Hopf
Department of Anesthesia and Perioperative Care, Department of Surgery, University of California, San Francisco, CA, USA
Methods Mol Med 78:389-416. 2003
Using physiology to improve surgical wound outcomesChristiane Ueno
University of California, San Francisco, Wound Healing Laboratory, Departments of Anesthesia and Perioperative Care and Surgery, San Francisco, Calif 94143-0648, USA
Plast Reconstr Surg 117:59S-71S. 2006..This article reviews how knowledge of and attention to physiology can improve quality of care in both acute and chronic wounds...
Development of subcutaneous wound oxygen measurement in humans: contributions of Thomas K Hunt, MDHarriet W Hopf
Department of Anesthesia and Perioperative Care, University of California, San Francisco, California 94143 0648, USA
Wound Repair Regen 11:424-30. 2003..All these observations required tissue oxygen measurement, and, in particular, translation of basic scientific observations to clinical research required a method of measuring wound oxygen tension in humans...
Oxygen reverses deficits of cognitive function and memory and increased heart rate induced by acute severe isovolemic anemiaRichard B Weiskopf
Department of Anesthesia, University of California, San Francisco, California 94143 0648, USA
Anesthesiology 96:871-7. 2002....
Acute isovolemic anemia does not impair peripheral or central nerve conductionRichard B Weiskopf
Department of Anesthesia, and Cardiovascular Research Institute, University of California, San Francisco, 94143 0648, USA
Anesthesiology 99:546-51. 2003..In this study, the authors tested the hypothesis that such changes relate to the slowing of afferent neural traffic...
Accuracy of a polarographic electrode at high oxygen concentrationsMark D Rollins
Bioengineering Graduate Group, University of California, San Francisco, CA, USA
Adv Exp Med Biol 510:169-73. 2003
Molecular diagnostics of injury and repair responses in critical illness: what is the future of "monitoring" in the intensive care unit?Harriet W Hopf
Department of Anesthesia and Perioperative Care, University of California, San Francisco, USA
Crit Care Med 31:S518-23. 2003..To identify potential future means of monitoring injury and repair in critical illness...
Facilitating positive outcomes in older adults with woundsNancy A Stotts
School of Nursing, University of California San Francisco, 2 Koret Way, No 631, San Francisco, CA 94143, USA
Nurs Clin North Am 40:267-79. 2005..These seemingly basic issues raise questions for clinicians as we strive to provide evidence-based care to this ever-increasing population of older Americans...
Increased fluid intake does not augment capacity to lay down new collagen in nursing home residents at risk for pressure ulcers: a randomized, controlled clinical trialNancy A Stotts
Department of Physiological Nursing, University of California San Francisco, San Francisco, California, USA
Wound Repair Regen 17:780-8. 2009..Further work is needed to examine the relationship between fluid intake and hydration in nursing home residents as well as the role of hydration in pressure ulcer prevention...
Paradigm of the injury-repair continuum during critical illnessLudwig H Lin
Department of Anesthesia and Perioperative Care, University of California-San Francisco, USA
Crit Care Med 31:S493-5. 2003....
Acute isovolemic anemia impairs central processing as determined by P300 latencyRichard B Weiskopf
Departments of Anesthesia and Physiology, Cardiovascular Research Institute, University of California, San Francisco, 94143 0648, USA
Clin Neurophysiol 116:1028-32. 2005..Acute anemia slows the responses to clinical tests of cognitive function. We tested the hypothesis that these slowed responses during acute severe isovolemic anemia in healthy unmedicated humans result from impaired central processing...
Wounds: an overview of the role of oxygenHarriet W Hopf
Department of Anesthesiology, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
Antioxid Redox Signal 9:1183-92. 2007..Our understanding of the role of oxygen in wound healing has been fueled by tissue oximetry. Advances in technology will lead to further advances in the management of patients with wounds...
Hyperoxia improves microvascular perfusion in a murine wound modelAhmad Y Sheikh
Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
Wound Repair Regen 13:303-8. 2005..05). Laser Doppler imaging was able to detect and quantify the increase in wound bed perfusion resulting from intermittent HBO treatments and shows promise as a noninvasive measure of angiogenesis and wound healing...
Supplemental oxygen and risk of surgical site infectionHarriet W Hopf
JAMA 291:1956; author reply 1958-9. 2004
The link between tissue oxygen and hydration in nursing home residents with pressure ulcers: preliminary dataNancy A Stotts
Department of Physiological Nursing, University of California-San Francisco, USA
J Wound Ostomy Continence Nurs 30:184-90. 2003..Further research in this area is warranted...
Perflubron emulsion increases subcutaneous tissue oxygen tension in ratsNoah A Rosen
Department of Surgery, Boston University Medical Center, Boston, Massachusetts, USA
Wound Repair Regen 14:55-60. 2006..0 vol%. These findings agree with those results analytically predicted based on the oxygen solubility of the perflubron emulsion...
Guidelines for the treatment of arterial insufficiency ulcersHarriet W Hopf
University of Utah, Salt Lake City, UT, USA
Wound Repair Regen 14:693-710. 2006
Is it time to retire high-concentration nitrous oxide?Harriet W Hopf
Anesthesiology 107:200-1. 2007
