Willemijntje A Hoogerwerf

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. ncbi request reprint Tachykinin receptors as drug targets for motility disorders
    Willemijntje A Hoogerwerf
    Department of Internal Medicine, Enteric Neuromuscular Disorders and Visceral Pain Center, Division of Gastroenterology, The University of Texas Medical Branch, Galveston, TX 77555 1064, USA
    Dig Dis 24:83-90. 2006
  2. pmc The impact of rotating shift work on the prevalence of irritable bowel syndrome in nurses
    Borko Nojkov
    Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan 48105, USA
    Am J Gastroenterol 105:842-7. 2010
  3. pmc Role of clock genes in gastrointestinal motility
    Willemijntje A Hoogerwerf
    Department of Internal Medicine, University of Michigan, Ann Arbor, 48105, USA
    Am J Physiol Gastrointest Liver Physiol 299:G549-55. 2010
  4. pmc Rhythmic changes in colonic motility are regulated by period genes
    Willemijntje A Hoogerwerf
    Department of Internal Medicine, Division of Gastroenterology, University of Michigan, VA Ann Arbor Healthcare System, 2215 Fuller Rd, Ann Arbor, MI 48105, USA
    Am J Physiol Gastrointest Liver Physiol 298:G143-50. 2010
  5. ncbi request reprint Clock gene expression in the murine gastrointestinal tract: endogenous rhythmicity and effects of a feeding regimen
    Willemijntje A Hoogerwerf
    Department of Internal Medicine, Division of Gastroenterology, University of Michigan, VA Ann Arbor Healthcare System, Ann Arbor, Michigan 48105, USA
    Gastroenterology 133:1250-60. 2007
  6. pmc Transcriptional profiling of mRNA expression in the mouse distal colon
    Willemijntje A Hoogerwerf
    Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48105, USA
    Gastroenterology 135:2019-29. 2008
  7. doi request reprint Role of biological rhythms in gastrointestinal health and disease
    Willemijntje A Hoogerwerf
    Department of Internal Medicine, Division of Gastroenterology, VA Ann Arbor Healthcare System, University of Michigan, 2215 Fuller Road, Ann Arbor, MI 48105, USA
    Rev Endocr Metab Disord 10:293-300. 2009
  8. doi request reprint Effects of acute and chronic STZ-induced diabetes on clock gene expression and feeding in the gastrointestinal tract
    Jonathon Bostwick
    Division of Gastroenterology, Department of Internal Medicine, University of Michigan, VA Ann Arbor Healthcare System, Ann Arbor, MI 48105, USA
    Mol Cell Biochem 338:203-13. 2010
  9. ncbi request reprint Biologic clocks and the gut
    Willemijntje A Hoogerwerf
    Department of Internal Medicine, Division of Gastroenterology, The University of Michigan, 1500 East Medical Center Drive, 3912 Taubman Center, Ann Arbor, MI 48109 0362, USA
    Curr Gastroenterol Rep 8:353-9. 2006
  10. pmc Expression of clock proteins in developing tooth
    Li Zheng
    Department of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI, USA
    Gene Expr Patterns 11:202-6. 2011

Detail Information

Publications10

  1. ncbi request reprint Tachykinin receptors as drug targets for motility disorders
    Willemijntje A Hoogerwerf
    Department of Internal Medicine, Enteric Neuromuscular Disorders and Visceral Pain Center, Division of Gastroenterology, The University of Texas Medical Branch, Galveston, TX 77555 1064, USA
    Dig Dis 24:83-90. 2006
    ..This is, in part, due to the complex and multilevel of regulation of gastrointestinal motility function and the challenges faced in targeting the specific type of gut contraction to normalize function in disease state...
  2. pmc The impact of rotating shift work on the prevalence of irritable bowel syndrome in nurses
    Borko Nojkov
    Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan 48105, USA
    Am J Gastroenterol 105:842-7. 2010
    ....
  3. pmc Role of clock genes in gastrointestinal motility
    Willemijntje A Hoogerwerf
    Department of Internal Medicine, University of Michigan, Ann Arbor, 48105, USA
    Am J Physiol Gastrointest Liver Physiol 299:G549-55. 2010
    ..This review will discuss new insights into the role of clock genes in colonic motility and their potential clinical relevance...
  4. pmc Rhythmic changes in colonic motility are regulated by period genes
    Willemijntje A Hoogerwerf
    Department of Internal Medicine, Division of Gastroenterology, University of Michigan, VA Ann Arbor Healthcare System, 2215 Fuller Rd, Ann Arbor, MI 48105, USA
    Am J Physiol Gastrointest Liver Physiol 298:G143-50. 2010
    ..These findings suggest that rhythms in colonic motility are regulated by both clock genes and a nNOS-mediated inhibitory process and suggest a connection between these two mechanisms...
  5. ncbi request reprint Clock gene expression in the murine gastrointestinal tract: endogenous rhythmicity and effects of a feeding regimen
    Willemijntje A Hoogerwerf
    Department of Internal Medicine, Division of Gastroenterology, University of Michigan, VA Ann Arbor Healthcare System, Ann Arbor, Michigan 48105, USA
    Gastroenterology 133:1250-60. 2007
    ..We hypothesized that clock genes are present in the gastrointestinal tract and that they are part of a functional molecular clock that coordinates rhythmic physiologic functions...
  6. pmc Transcriptional profiling of mRNA expression in the mouse distal colon
    Willemijntje A Hoogerwerf
    Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48105, USA
    Gastroenterology 135:2019-29. 2008
    ..Because disruption of the biological clock has been associated with increased susceptibility to colon cancer and gastrointestinal symptoms, we aimed to identify rhythmically expressed genes in the mouse distal colon...
  7. doi request reprint Role of biological rhythms in gastrointestinal health and disease
    Willemijntje A Hoogerwerf
    Department of Internal Medicine, Division of Gastroenterology, VA Ann Arbor Healthcare System, University of Michigan, 2215 Fuller Road, Ann Arbor, MI 48105, USA
    Rev Endocr Metab Disord 10:293-300. 2009
    ....
  8. doi request reprint Effects of acute and chronic STZ-induced diabetes on clock gene expression and feeding in the gastrointestinal tract
    Jonathon Bostwick
    Division of Gastroenterology, Department of Internal Medicine, University of Michigan, VA Ann Arbor Healthcare System, Ann Arbor, MI 48105, USA
    Mol Cell Biochem 338:203-13. 2010
    ..Alterations in clock gene expression in a mouse model of diabetes are most pronounced in those organs that are intimately associated with food processing and metabolism...
  9. ncbi request reprint Biologic clocks and the gut
    Willemijntje A Hoogerwerf
    Department of Internal Medicine, Division of Gastroenterology, The University of Michigan, 1500 East Medical Center Drive, 3912 Taubman Center, Ann Arbor, MI 48109 0362, USA
    Curr Gastroenterol Rep 8:353-9. 2006
    ....
  10. pmc Expression of clock proteins in developing tooth
    Li Zheng
    Department of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI, USA
    Gene Expr Patterns 11:202-6. 2011
    ..Our data suggests that clock genes might be involved in the regulation of ameloblast and odontoblast functions, such as enamel and dentin protein secretion and matrix mineralization...