Seung-Mo Hong

Summary

Affiliation: University of Virginia
Country: USA

Publications

  1. ncbi Measurement of the invasion depth of extrahepatic bile duct carcinoma: An alternative method overcoming the current T classification problems of the AJCC staging system
    Seung Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    Am J Surg Pathol 31:199-206. 2007
  2. ncbi Reconsideration of the histologic definitions used in the pathologic staging of extrahepatic bile duct carcinoma
    Seung Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville, VA 22908, USA
    Am J Surg Pathol 30:744-9. 2006
  3. ncbi p63 and p73 expression in extrahepatic bile duct carcinoma and their clinical significance
    Seung Mo Hong
    Department of Pathology, Johns Hopkins University, Baltimore, MD, USA
    J Mol Histol 38:167-75. 2007
  4. ncbi Genome-wide profiling of methylated promoters in pancreatic adenocarcinoma
    Noriyuki Omura
    Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA
    Cancer Biol Ther 7:1146-56. 2008
  5. ncbi CDX2 and MUC2 protein expression in extrahepatic bile duct carcinoma
    Seung-Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville, USA
    Am J Clin Pathol 124:361-70. 2005
  6. ncbi Clinical and prognostic significances of nuclear and cytoplasmic KIT expressions in extrahepatic bile duct carcinomas
    Seung Mo Hong
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Mod Pathol 20:562-9. 2007
  7. ncbi The number of metastatic lymph nodes in extrahepatic bile duct carcinoma as a prognostic factor
    Seung-Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville, VA, USA
    Am J Surg Pathol 29:1177-83. 2005
  8. ncbi AP-2gamma protein expression in intratubular germ cell neoplasia of testis
    Seung-Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville 22908, USA
    Am J Clin Pathol 124:873-7. 2005
  9. ncbi Pancreatic cancer associated fibroblasts display normal allelotypes
    Kimberly Walter
    Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA
    Cancer Biol Ther 7:882-8. 2008
  10. ncbi Promoter hypermethylation of the p16 gene and loss of its protein expression is correlated with tumor progression in extrahepatic bile duct carcinomas
    Seung-Mo Hong
    Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Arch Pathol Lab Med 130:33-8. 2006

Collaborators

  • HyungJun Cho
  • Henry F Frierson
  • Jae Y Ro
  • Manuel Hidalgo
  • Ang Li
  • Antonio Jimeno
  • Alexander I Zaika
  • Edward B Stelow
  • Fausto Sessa
  • N Volkan Adsay
  • Alberto Quaglia
  • Giovanni Parmigiani
  • G Kloppel
  • G Y Lauwers
  • Kyu-Rae Kim
  • Kimberly Walter
  • Michael Goggins
  • Noriyuki Omura
  • Sian Jones
  • Yoh Zen
  • Mi-Jung Kim
  • Ok Jae Lee
  • Jin-Hee Ahn
  • Elizabeth M Jaffee
  • Anirban Maitra
  • James Hartigan
  • Kenneth W Kinzler
  • Rachel Karchin
  • Ming Tseh Lin
  • Hirohiko Kamiyama
  • Xiaosong Zhang
  • Hannah Carter
  • D Williams Parsons
  • Jimmy Cheng Ho Lin
  • Chung-Pin Li
  • Ralph H Hruban
  • Douglas R Smith
  • Jimmy Cheng-Ho Lin
  • Ming-Tseh Lin
  • Tatiana Nikolskaya
  • Nickolas Papadopoulos
  • Eric S Calhoun
  • Mihoko Kamiyama
  • Yuri Nikolsky
  • Rebecca J Leary
  • Steven D Leach
  • Victor E Velculescu
  • Christine Iacobuzio-Donahue
  • Philipp Angenendt
  • Bert Vogelstein
  • Parminder Mankoo
  • Scott E Kern
  • James R Eshleman
  • Margaret Griffith
  • Baojin Fu
  • Chung Pin Li
  • Alison P Klein
  • Kenji Notohara
  • Romano Colombari
  • Yutaka Atomi
  • Linda Ferrell
  • Yasuni Nakanuma
  • Hironori Haga
  • Motoko Sasaki
  • Wilson Tsui
  • Dirk J van Leeuwen
  • Kiyoko Oshima
  • Arief Suriawinata
  • Prodromos Hytiroglou
  • Krystof Bardadin
  • Mark Smoklin
  • Mohammad H Razvi
  • Jung-Sun Kim
  • Gyungyub Gong
  • Se J Jang
  • Christopher A Moskaluk
  • Steven M Powell
  • Wael El-Rifai
  • Ok-Jae Lee
  • Dunfa Peng
  • Eunsil Yu
  • Sang-We Kim
  • Cheolwon Suh
  • Woo Kun Kim
  • In Chul Lee
  • Jung-Shin Lee

Detail Information

Publications18

  1. ncbi Measurement of the invasion depth of extrahepatic bile duct carcinoma: An alternative method overcoming the current T classification problems of the AJCC staging system
    Seung Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    Am J Surg Pathol 31:199-206. 2007
    ....
  2. ncbi Reconsideration of the histologic definitions used in the pathologic staging of extrahepatic bile duct carcinoma
    Seung Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville, VA 22908, USA
    Am J Surg Pathol 30:744-9. 2006
    ....
  3. ncbi p63 and p73 expression in extrahepatic bile duct carcinoma and their clinical significance
    Seung Mo Hong
    Department of Pathology, Johns Hopkins University, Baltimore, MD, USA
    J Mol Histol 38:167-75. 2007
    ..Our results strongly imply that the p53 family members have different functions in EBD carcinomas. Our data also indicate that interactions between p63 and p73 play an important role in tumorigenesis of EBD carcinoma...
  4. ncbi Genome-wide profiling of methylated promoters in pancreatic adenocarcinoma
    Noriyuki Omura
    Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA
    Cancer Biol Ther 7:1146-56. 2008
    ..Many genes undergo aberrant methylation in human cancers, and microarray platforms enable more comprehensive profiling of aberrant DNA methylation patterns...
  5. ncbi CDX2 and MUC2 protein expression in extrahepatic bile duct carcinoma
    Seung-Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville, USA
    Am J Clin Pathol 124:361-70. 2005
    ..05). Expression of CDX2 and MUC2 supports that intestinal differentiation is present in specific subtypes of EBD carcinomas, and their expression status correlates with patients' overall survival...
  6. ncbi Clinical and prognostic significances of nuclear and cytoplasmic KIT expressions in extrahepatic bile duct carcinomas
    Seung Mo Hong
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Mod Pathol 20:562-9. 2007
    ..In addition, more frequent nuclear expression of KIT in cases with vascular invasion suggests that nuclear KIT expression may contribute to the progression of extrahepatic bile duct carcinoma...
  7. ncbi The number of metastatic lymph nodes in extrahepatic bile duct carcinoma as a prognostic factor
    Seung-Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville, VA, USA
    Am J Surg Pathol 29:1177-83. 2005
    ..Based on the present data, we propose that nodal classification should be divided into N1 (metastasis in 1 to 4 regional lymph nodes) and N2 (metastasis in 5 or more regional lymph nodes)...
  8. ncbi AP-2gamma protein expression in intratubular germ cell neoplasia of testis
    Seung-Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville 22908, USA
    Am J Clin Pathol 124:873-7. 2005
    ..All 3 markers were negative in normal testis (0 of 11 cases). DNA binding sites in the promoter region forAP-2gamma in the PLAP and c-kit genes might explain the concordance of protein expression...
  9. ncbi Pancreatic cancer associated fibroblasts display normal allelotypes
    Kimberly Walter
    Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA
    Cancer Biol Ther 7:882-8. 2008
    ..The aim of this study was to determine if pancreatic cancer associated fibroblasts display similar genetic alterations...
  10. ncbi Promoter hypermethylation of the p16 gene and loss of its protein expression is correlated with tumor progression in extrahepatic bile duct carcinomas
    Seung-Mo Hong
    Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Arch Pathol Lab Med 130:33-8. 2006
    ..Furthermore, the loss of p16 expression, with or without p16 gene promoter hypermethylation, is closely related to the tumor progression in EBD carcinomas...
  11. ncbi Neuroendocrine differentiation in extrahepatic bile duct carcinomas and its prognostic significance
    Seung-Mo Hong
    Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, South Korea
    Hum Pathol 36:732-40. 2005
    ..Therefore, immunohistochemical studies for neuroendocrine differentiation may be helpful in routine pathological examinations for evaluating the survival and the prognosis of patients with EBD carcinomas...
  12. ncbi Analysis of extrahepatic bile duct carcinomas according to the New American Joint Committee on Cancer staging system focused on tumor classification problems in 222 patients
    Seung-Mo Hong
    Department of Pathology, Asan Medical Center, University of Ulsan Medical College, Seoul, Korea
    Cancer 104:802-10. 2005
    ..Therefore, the authors recommended changing the current pT1 and pT2 classifications to more precise pathologic terminology...
  13. ncbi Superficial vs deep pancreatic parenchymal invasion in the extrahepatic bile duct carcinomas: a significant prognostic factor
    Seung-Mo Hong
    Department of Pathology, Asan Medical Center, University of Ulsan, Seoul, Korea
    Mod Pathol 18:969-75. 2005
    ..We also recommend that the current pT3 stage of distal EBD carcinomas be subdivided into superficial (pT3a) and deep pancreatic invasion (pT3b)...
  14. ncbi Epidermal growth factor receptor (EGFR) expression in operable non-small cell lung carcinoma
    Jin-Hee Ahn
    Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    J Korean Med Sci 19:529-35. 2004
    ..45%, p-value 0.3382) rates. In conclusion, our findings suggest that NSCLC proliferative activity may be dependent on EGFR expression, but that EGFR expression had no significant impact on survival in curatively resected NSCLC...
  15. ncbi Biliary intraepithelial neoplasia: an international interobserver agreement study and proposal for diagnostic criteria
    Yoh Zen
    Department of Human Pathology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan
    Mod Pathol 20:701-9. 2007
    ..This classification should help to advance clinical and research applications...
  16. ncbi Expression of calcium-binding proteins S100A2 and S100A4 in Barrett's adenocarcinomas
    Ok Jae Lee
    Department of Surgery and Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Neoplasia 8:843-50. 2006
    ..027). These results demonstrate frequent cytosolic overexpression of S100A2 and S100A4 in BAs. Further studies are ongoing to understand the biological significance of these S100A proteins in Barrett's tumorigenesis...
  17. ncbi Invasive colorectal micropapillary carcinoma: an aggressive variant of adenocarcinoma
    Mi-Jung Kim
    Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138-730, South Korea
    Hum Pathol 37:809-15. 2006
    ..The proportion of MC component did not impact the prognosis, and the immunoprofiles of MC were not significantly different from those of conventional adenocarcinoma...
  18. ncbi Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
    Sian Jones
    Sol Goldman Pancreatic Cancer Research Center, Ludwig Center and Howard Hughes Medical Institute at the Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21231, USA
    Science 321:1801-6. 2008
    ..Dysregulation of these core pathways and processes through mutation can explain the major features of pancreatic tumorigenesis...