Seung-Mo Hong

Summary

Affiliation: University of Virginia
Country: USA

Publications

  1. ncbi request reprint Measurement of the invasion depth of extrahepatic bile duct carcinoma: An alternative method overcoming the current T classification problems of the AJCC staging system
    Seung Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    Am J Surg Pathol 31:199-206. 2007
  2. ncbi request reprint Reconsideration of the histologic definitions used in the pathologic staging of extrahepatic bile duct carcinoma
    Seung Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville, VA 22908, USA
    Am J Surg Pathol 30:744-9. 2006
  3. ncbi request reprint p63 and p73 expression in extrahepatic bile duct carcinoma and their clinical significance
    Seung Mo Hong
    Department of Pathology, Johns Hopkins University, Baltimore, MD, USA
    J Mol Histol 38:167-75. 2007
  4. pmc Genome-wide profiling of methylated promoters in pancreatic adenocarcinoma
    Noriyuki Omura
    Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA
    Cancer Biol Ther 7:1146-56. 2008
  5. ncbi request reprint CDX2 and MUC2 protein expression in extrahepatic bile duct carcinoma
    Seung Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville, USA
    Am J Clin Pathol 124:361-70. 2005
  6. ncbi request reprint Clinical and prognostic significances of nuclear and cytoplasmic KIT expressions in extrahepatic bile duct carcinomas
    Seung Mo Hong
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Mod Pathol 20:562-9. 2007
  7. ncbi request reprint The number of metastatic lymph nodes in extrahepatic bile duct carcinoma as a prognostic factor
    Seung Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville, VA, USA
    Am J Surg Pathol 29:1177-83. 2005
  8. ncbi request reprint AP-2gamma protein expression in intratubular germ cell neoplasia of testis
    Seung Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville 22908, USA
    Am J Clin Pathol 124:873-7. 2005
  9. pmc Pancreatic cancer associated fibroblasts display normal allelotypes
    Kimberly Walter
    Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA
    Cancer Biol Ther 7:882-8. 2008
  10. ncbi request reprint Promoter hypermethylation of the p16 gene and loss of its protein expression is correlated with tumor progression in extrahepatic bile duct carcinomas
    Seung Mo Hong
    Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Arch Pathol Lab Med 130:33-8. 2006

Collaborators

  • HyungJun Cho
  • Henry F Frierson
  • Jae Y Ro
  • Manuel Hidalgo
  • Ang Li
  • Antonio Jimeno
  • Alexander I Zaika
  • Edward B Stelow
  • Fausto Sessa
  • N Volkan Adsay
  • Alberto Quaglia
  • Giovanni Parmigiani
  • G Kloppel
  • G Y Lauwers
  • Kyu-Rae Kim
  • Kimberly Walter
  • Michael Goggins
  • Noriyuki Omura
  • Sian Jones
  • Yoh Zen
  • Ok Jae Lee
  • Mi Jung Kim
  • Jin Hee Ahn
  • Nickolas Papadopoulos
  • Rachel Karchin
  • Elizabeth M Jaffee
  • D Williams Parsons
  • Baojin Fu
  • Jimmy Cheng Ho Lin
  • Scott E Kern
  • Hannah Carter
  • Ming Tseh Lin
  • Margaret Griffith
  • Hirohiko Kamiyama
  • Ralph H Hruban
  • Victor E Velculescu
  • James Hartigan
  • Philipp Angenendt
  • Alison P Klein
  • Kenneth W Kinzler
  • James R Eshleman
  • Steven D Leach
  • Anirban Maitra
  • Tatiana Nikolskaya
  • Eric S Calhoun
  • Chung Pin Li
  • Christine Iacobuzio-Donahue
  • Xiaosong Zhang
  • Bert Vogelstein
  • Mihoko Kamiyama
  • Douglas R Smith
  • Yuri Nikolsky
  • Parminder Mankoo
  • Rebecca J Leary
  • Kiyoko Oshima
  • Yasuni Nakanuma
  • Prodromos Hytiroglou
  • Hironori Haga
  • Dirk J van Leeuwen
  • Yutaka Atomi
  • Kenji Notohara
  • Wilson Tsui
  • Arief Suriawinata
  • Motoko Sasaki
  • Romano Colombari
  • Krystof Bardadin
  • Linda Ferrell
  • Se J Jang
  • Gyungyub Gong
  • Eunsil Yu
  • Jung Sun Kim
  • Wael El-Rifai
  • Christopher A Moskaluk
  • Dunfa Peng
  • Mark Smoklin
  • Steven M Powell
  • Mohammad H Razvi
  • Cheolwon Suh
  • In Chul Lee
  • Sang We Kim
  • Woo Kun Kim
  • Jung Shin Lee

Detail Information

Publications18

  1. ncbi request reprint Measurement of the invasion depth of extrahepatic bile duct carcinoma: An alternative method overcoming the current T classification problems of the AJCC staging system
    Seung Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    Am J Surg Pathol 31:199-206. 2007
    ....
  2. ncbi request reprint Reconsideration of the histologic definitions used in the pathologic staging of extrahepatic bile duct carcinoma
    Seung Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville, VA 22908, USA
    Am J Surg Pathol 30:744-9. 2006
    ....
  3. ncbi request reprint p63 and p73 expression in extrahepatic bile duct carcinoma and their clinical significance
    Seung Mo Hong
    Department of Pathology, Johns Hopkins University, Baltimore, MD, USA
    J Mol Histol 38:167-75. 2007
    ..Our results strongly imply that the p53 family members have different functions in EBD carcinomas. Our data also indicate that interactions between p63 and p73 play an important role in tumorigenesis of EBD carcinoma...
  4. pmc Genome-wide profiling of methylated promoters in pancreatic adenocarcinoma
    Noriyuki Omura
    Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA
    Cancer Biol Ther 7:1146-56. 2008
    ..Many genes undergo aberrant methylation in human cancers, and microarray platforms enable more comprehensive profiling of aberrant DNA methylation patterns...
  5. ncbi request reprint CDX2 and MUC2 protein expression in extrahepatic bile duct carcinoma
    Seung Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville, USA
    Am J Clin Pathol 124:361-70. 2005
    ..05). Expression of CDX2 and MUC2 supports that intestinal differentiation is present in specific subtypes of EBD carcinomas, and their expression status correlates with patients' overall survival...
  6. ncbi request reprint Clinical and prognostic significances of nuclear and cytoplasmic KIT expressions in extrahepatic bile duct carcinomas
    Seung Mo Hong
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Mod Pathol 20:562-9. 2007
    ..In addition, more frequent nuclear expression of KIT in cases with vascular invasion suggests that nuclear KIT expression may contribute to the progression of extrahepatic bile duct carcinoma...
  7. ncbi request reprint The number of metastatic lymph nodes in extrahepatic bile duct carcinoma as a prognostic factor
    Seung Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville, VA, USA
    Am J Surg Pathol 29:1177-83. 2005
    ..Based on the present data, we propose that nodal classification should be divided into N1 (metastasis in 1 to 4 regional lymph nodes) and N2 (metastasis in 5 or more regional lymph nodes)...
  8. ncbi request reprint AP-2gamma protein expression in intratubular germ cell neoplasia of testis
    Seung Mo Hong
    Department of Pathology, University of Virginia Health System, Charlottesville 22908, USA
    Am J Clin Pathol 124:873-7. 2005
    ..All 3 markers were negative in normal testis (0 of 11 cases). DNA binding sites in the promoter region forAP-2gamma in the PLAP and c-kit genes might explain the concordance of protein expression...
  9. pmc Pancreatic cancer associated fibroblasts display normal allelotypes
    Kimberly Walter
    Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA
    Cancer Biol Ther 7:882-8. 2008
    ..The aim of this study was to determine if pancreatic cancer associated fibroblasts display similar genetic alterations...
  10. ncbi request reprint Promoter hypermethylation of the p16 gene and loss of its protein expression is correlated with tumor progression in extrahepatic bile duct carcinomas
    Seung Mo Hong
    Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Arch Pathol Lab Med 130:33-8. 2006
    ..Promoter hypermethylation, a mechanism of p16 gene inactivation, has been reported to play an important role in tumorigenesis and to be related to patient prognosis in several carcinomas...
  11. ncbi request reprint Neuroendocrine differentiation in extrahepatic bile duct carcinomas and its prognostic significance
    Seung Mo Hong
    Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138 736, South Korea
    Hum Pathol 36:732-40. 2005
    ..Therefore, immunohistochemical studies for neuroendocrine differentiation may be helpful in routine pathological examinations for evaluating the survival and the prognosis of patients with EBD carcinomas...
  12. ncbi request reprint Analysis of extrahepatic bile duct carcinomas according to the New American Joint Committee on Cancer staging system focused on tumor classification problems in 222 patients
    Seung Mo Hong
    Department of Pathology, Asan Medical Center, University of Ulsan Medical College, Seoul, Korea
    Cancer 104:802-10. 2005
    ..quot;..
  13. ncbi request reprint Superficial vs deep pancreatic parenchymal invasion in the extrahepatic bile duct carcinomas: a significant prognostic factor
    Seung Mo Hong
    Department of Pathology, Asan Medical Center, University of Ulsan, Seoul, Korea
    Mod Pathol 18:969-75. 2005
    ..We also recommend that the current pT3 stage of distal EBD carcinomas be subdivided into superficial (pT3a) and deep pancreatic invasion (pT3b)...
  14. pmc Epidermal growth factor receptor (EGFR) expression in operable non-small cell lung carcinoma
    Jin Hee Ahn
    Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    J Korean Med Sci 19:529-35. 2004
    ..45%, p-value 0.3382) rates. In conclusion, our findings suggest that NSCLC proliferative activity may be dependent on EGFR expression, but that EGFR expression had no significant impact on survival in curatively resected NSCLC...
  15. ncbi request reprint Biliary intraepithelial neoplasia: an international interobserver agreement study and proposal for diagnostic criteria
    Yoh Zen
    Department of Human Pathology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan
    Mod Pathol 20:701-9. 2007
    ..This classification should help to advance clinical and research applications...
  16. pmc Expression of calcium-binding proteins S100A2 and S100A4 in Barrett's adenocarcinomas
    Ok Jae Lee
    Department of Surgery and Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Neoplasia 8:843-50. 2006
    ..027). These results demonstrate frequent cytosolic overexpression of S100A2 and S100A4 in BAs. Further studies are ongoing to understand the biological significance of these S100A proteins in Barrett's tumorigenesis...
  17. ncbi request reprint Invasive colorectal micropapillary carcinoma: an aggressive variant of adenocarcinoma
    Mi Jung Kim
    Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138 730, South Korea
    Hum Pathol 37:809-15. 2006
    ..The proportion of MC component did not impact the prognosis, and the immunoprofiles of MC were not significantly different from those of conventional adenocarcinoma...
  18. pmc Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
    Sian Jones
    Sol Goldman Pancreatic Cancer Research Center, Ludwig Center and Howard Hughes Medical Institute at the Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21231, USA
    Science 321:1801-6. 2008
    ..Dysregulation of these core pathways and processes through mutation can explain the major features of pancreatic tumorigenesis...