L Elliot Hong

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. pmc Evidence of missense mutations on the neuregulin 1 gene affecting function of prepulse inhibition
    L Elliot Hong
    Department of Psychiatry, Maryland Psychiatric Research Center, Baltimore, Maryland 21228, USA
    Biol Psychiatry 63:17-23. 2008
  2. pmc Brain circuits that link schizophrenia to high risk of cigarette smoking
    Lauren V Moran
    To whom correspondence should be addressed Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, PO Box 21247, Baltimore, MD 21228, US tel 410 402 6828, fax 410 402 6023, E mail
    Schizophr Bull 39:1373-81. 2013
  3. pmc Mismatch negativity and low frequency oscillations in schizophrenia families
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore 21228, USA
    Clin Neurophysiol 123:1980-8. 2012
  4. pmc A shared low-frequency oscillatory rhythm abnormality in resting and sensory gating in schizophrenia
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21247, USA
    Clin Neurophysiol 123:285-92. 2012
  5. pmc Refining the predictive pursuit endophenotype in schizophrenia
    L Elliot Hong
    Maryland Psychiatric Research Center, Lions Vision Center, Johns Hopkins School of Medicine, Baltimore, Maryland 21228, USA
    Biol Psychiatry 63:458-64. 2008
  6. ncbi request reprint Nicotine effect on prepulse inhibition and prepulse facilitation in schizophrenia patients
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    Neuropsychopharmacology 33:2167-74. 2008
  7. ncbi request reprint Beta (~16 Hz) frequency neural oscillations mediate auditory sensory gating in humans
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    Psychophysiology 45:197-204. 2008
  8. pmc Sensory gating endophenotype based on its neural oscillatory pattern and heritability estimate
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    Arch Gen Psychiatry 65:1008-16. 2008
  9. pmc Is motion perception deficit in schizophrenia a consequence of eye-tracking abnormality?
    L Elliot Hong
    Department of Psychiatry, Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, Maryland 21228, USA
    Biol Psychiatry 65:1079-85. 2009
  10. pmc Association of nicotine addiction and nicotine's actions with separate cingulate cortex functional circuits
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, PO Box 21247, Baltimore, MD 21228, USA
    Arch Gen Psychiatry 66:431-41. 2009

Detail Information

Publications52

  1. pmc Evidence of missense mutations on the neuregulin 1 gene affecting function of prepulse inhibition
    L Elliot Hong
    Department of Psychiatry, Maryland Psychiatric Research Center, Baltimore, Maryland 21228, USA
    Biol Psychiatry 63:17-23. 2008
    ..A widely used surrogate measure of psychosis in animal models, PPI is considered a schizophrenia endophenotype. We hypothesized that if NRG1 influences PPI in rodents, then it should have a similar effect on PPI in humans...
  2. pmc Brain circuits that link schizophrenia to high risk of cigarette smoking
    Lauren V Moran
    To whom correspondence should be addressed Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, PO Box 21247, Baltimore, MD 21228, US tel 410 402 6828, fax 410 402 6023, E mail
    Schizophr Bull 39:1373-81. 2013
    ..Our findings establish a biologically defined brain circuit mechanism that contributes to the high prevalence of smoking. ..
  3. pmc Mismatch negativity and low frequency oscillations in schizophrenia families
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore 21228, USA
    Clin Neurophysiol 123:1980-8. 2012
    ..We aimed to test the hypothesis that theta-alpha activities may contribute to MMN in schizophrenia patients and their family members...
  4. pmc A shared low-frequency oscillatory rhythm abnormality in resting and sensory gating in schizophrenia
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21247, USA
    Clin Neurophysiol 123:285-92. 2012
    ..We hypothesized that an oscillatory abnormality that is consistently observed across various testing paradigms may index an elementary neuronal abnormality marking schizophrenia risk...
  5. pmc Refining the predictive pursuit endophenotype in schizophrenia
    L Elliot Hong
    Maryland Psychiatric Research Center, Lions Vision Center, Johns Hopkins School of Medicine, Baltimore, Maryland 21228, USA
    Biol Psychiatry 63:458-64. 2008
    ..Previous work has shown a reduced predictive pursuit response to a briefly masked (i.e., invisible) moving object in schizophrenia. However, the overt awareness of target removal can confound the measurement...
  6. ncbi request reprint Nicotine effect on prepulse inhibition and prepulse facilitation in schizophrenia patients
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    Neuropsychopharmacology 33:2167-74. 2008
    ..002). In conclusion, the findings confirmed that nicotine transiently improves acoustic PPI in schizophrenia patients. Additionally, schizophrenia patients with more clinical symptoms may have benefited more from nicotinic effect on PPI...
  7. ncbi request reprint Beta (~16 Hz) frequency neural oscillations mediate auditory sensory gating in humans
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    Psychophysiology 45:197-204. 2008
    ..The results suggested that beta oscillation indexed a neural process associated with the strength of sensory gating...
  8. pmc Sensory gating endophenotype based on its neural oscillatory pattern and heritability estimate
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    Arch Gen Psychiatry 65:1008-16. 2008
    ..Frequency-specific sensory gating may be less complex than the P50 response, and therefore closer to the direct genetic effects, and thus a more valid endophenotype...
  9. pmc Is motion perception deficit in schizophrenia a consequence of eye-tracking abnormality?
    L Elliot Hong
    Department of Psychiatry, Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, Maryland 21228, USA
    Biol Psychiatry 65:1079-85. 2009
    ..However, eye movement closely interacts with motion perception. The known eye-tracking difficulties in schizophrenia patients may interact with their motion perception...
  10. pmc Association of nicotine addiction and nicotine's actions with separate cingulate cortex functional circuits
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, PO Box 21247, Baltimore, MD 21228, USA
    Arch Gen Psychiatry 66:431-41. 2009
    ..Imaging studies showed that nicotine challenges almost always involve the cingulate cortex, suggesting that this locus may be a key region associated with nicotine addiction and its treatment...
  11. pmc Nicotine enhances but does not normalize visual sustained attention and the associated brain network in schizophrenia
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA
    Schizophr Bull 37:416-25. 2011
    ..These findings provide guidance for developing new treatment strategies for the sustained attention deficit in schizophrenia...
  12. pmc Gamma and delta neural oscillations and association with clinical symptoms under subanesthetic ketamine
    L Elliot Hong
    Department of Psychiatry, Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    Neuropsychopharmacology 35:632-40. 2010
    ..These electrical oscillatory indexes of subanesthetic ketamine can be potentially used to cross-examine glutamatergic pharmacological effects in translational animal and human studies...
  13. pmc A genetically modulated, intrinsic cingulate circuit supports human nicotine addiction
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    Proc Natl Acad Sci U S A 107:13509-14. 2010
    ..Identifying where and how brain circuits link genes to smoking provides practical neural circuitry targets for new treatment development...
  14. pmc A CHRNA5 allele related to nicotine addiction and schizophrenia
    L E Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    Genes Brain Behav 10:530-5. 2011
    ....
  15. pmc Effects of moderate-dose treatment with varenicline on neurobiological and cognitive biomarkers in smokers and nonsmokers with schizophrenia or schizoaffective disorder
    L Elliot Hong
    Maryland Psychiatric Research Center, Baltimore, MD 21228, USA
    Arch Gen Psychiatry 68:1195-206. 2011
    ..It is not yet clear which nicotinic acetylcholine receptor (nAChR) subtype or subtypes are responsible for these seemingly pervasive nicotinic effects in schizophrenia and schizoaffective disorder...
  16. ncbi request reprint Independent domains of inhibitory gating in schizophrenia and the effect of stimulus interval
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, P O Box 21247, Baltimore, MD 21228, USA
    Am J Psychiatry 164:61-5. 2007
    ..The authors hypothesized that the relationship of the two measures may vary as a function of interstimulus intervals of stimulus presentations...
  17. ncbi request reprint Gamma/beta oscillation and sensory gating deficit in schizophrenia
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, School of Medicine, University of Maryland, PO Box 21247, Baltimore, MD 21228, USA
    Neuroreport 15:155-9. 2004
    ..The results of the present study showed that post-SI beta frequency response was inversely correlated to the S2 P50 response in patients with schizophrenia...
  18. ncbi request reprint Specific motion processing pathway deficit during eye tracking in schizophrenia: a performance-matched functional magnetic resonance imaging study
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore 21228, USA
    Biol Psychiatry 57:726-32. 2005
    ....
  19. ncbi request reprint Dihydropyrimidinase-related protein 2 (DRP-2) gene and association to deficit and nondeficit schizophrenia
    L Elliot Hong
    Department of Psychiatry, Maryland Psychiatric Research Center, School of Medicine, University of Maryland, Baltimore, 21228, USA
    Am J Med Genet B Neuropsychiatr Genet 136:8-11. 2005
    ..2%, P =0.050) forms of schizophrenia compared to controls (allele frequency 25.0%). We conclude that the DRP-2 *2236 C allele may mark another polymorphism in DRP-2, or in a nearby gene, that may influence susceptibility to schizophrenia...
  20. ncbi request reprint Response to unexpected target changes during sustained visual tracking in schizophrenic patients
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, P O Box 21247, Baltimore, MD 21228, USA
    Exp Brain Res 165:125-31. 2005
    ..Data suggest that at-risk individuals for schizophrenia depend less on extraretinal and more on retinal motion signals to maintain pursuit than healthy individuals...
  21. ncbi request reprint Reliability of a portable head-mounted eye tracking instrument for schizophrenia research
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore, MD 21228, USA
    Behav Res Methods 37:133-8. 2005
    ..96). This result suggests that the portable device is comparable with a lab-based system, which makes possible the collection of eye movement data in community-based and multicenter familial studies of schizophrenia...
  22. ncbi request reprint Familial aggregation of eye-tracking endophenotypes in families of schizophrenic patients
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, USA
    Arch Gen Psychiatry 63:259-64. 2006
    ..Recent studies have suggested that deficit in predictive pursuit, a specific component of the SPEMs, marks schizophrenia susceptibility...
  23. ncbi request reprint Components of the smooth pursuit function in deficit and nondeficit schizophrenia
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, P O Box 21247, Baltimore, MD 21228, USA
    Schizophr Res 63:39-48. 2003
    ..These findings suggest that predictive smooth pursuit abnormality is associated with positive symptoms in schizophrenia, and that initiation abnormalities may be associated with the deficit syndrome...
  24. ncbi request reprint Evoked gamma band synchronization and the liability for schizophrenia
    L Elliot Hong
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, P O Box 21247, Baltimore, MD 21228, USA
    Schizophr Res 70:293-302. 2004
    ....
  25. pmc Electrophysiological intermediate biomarkers for oxidative stress in schizophrenia
    Alejandro Ballesteros
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, School of Medicine, Baltimore, MD, United States Hospital ClĂ­nico de Salamanca, Department of Psychiatry, Salamanca, Spain
    Clin Neurophysiol 124:2209-15. 2013
    ..We tested whether the altered oxidative stress in schizophrenia contributes to the electrophysiological abnormalities...
  26. pmc Dopamine transporter polymorphism modulates oculomotor function and DAT1 mRNA expression in schizophrenia
    Ikwunga Wonodi
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, 21228, USA
    Am J Med Genet B Neuropsychiatr Genet 150:282-9. 2009
    ..05), but higher expression in schizophrenia donors. Findings suggest regulatory effects of another gene(s) or etiological factor in schizophrenia, which modulate DAT1 gene function...
  27. pmc Insular and anterior cingulate circuits in smokers with schizophrenia
    Lauren V Moran
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    Schizophr Res 142:223-9. 2012
    ..Decreased insula-dACC rsFC may index overlapping circuitry associated with smoking and SZ...
  28. ncbi request reprint Tardive dyskinesia in children treated with atypical antipsychotic medications
    Ikwunga Wonodi
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland 21228, USA
    Mov Disord 22:1777-82. 2007
    ..Ethnicity might also be a risk factor for dyskinesia in children. Side-effect profile of the atypical antipsychotic drugs in children may be much different than that in adults...
  29. pmc No evidence of exogenous origin for the abnormal glutathione redox state in schizophrenia
    Alejandro Ballesteros
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, 55 Wade Avenue, 21228 Catonsville, MD, USA
    Schizophr Res 146:184-9. 2013
    ..In conclusion, none of the exogenous sources played a major role in explaining abnormalities in the glutathione pathway in patients. The state of abnormal glutathione redox may therefore be a part of schizophrenia pathophysiology...
  30. pmc High vs low frequency neural oscillations in schizophrenia
    Lauren V Moran
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    Schizophr Bull 37:659-63. 2011
    ..The review concludes that studying the full spectrum and the interaction of gamma and low frequency oscillations may be critical for deciphering the complex electrophysiological abnormalities observed in schizophrenia patients...
  31. pmc Dipyridamole monotherapy in schizophrenia: pilot of a novel treatment approach by modulation of purinergic signaling
    Ikwunga Wonodi
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, P O Box 21247, Baltimore, MD 21228, USA
    Psychopharmacology (Berl) 218:341-5. 2011
    ..One previous clinical trial showed superiority of adjunctive dipyridamole, an adenosine reuptake inhibitor, compared to placebo in ameliorating positive symptoms in schizophrenia patients...
  32. doi request reprint Prefrontal white matter impairment in substance users depends upon the catechol-o-methyl transferase (COMT) val158met polymorphism
    Xiaochu Zhang
    Neuroimaging Research Branch, National Institute on Drug Abuse, NIH, Baltimore, MD 21224, USA
    Neuroimage 69:62-9. 2013
    ....
  33. ncbi request reprint Naltrexone treatment of tardive dyskinesia in patients with schizophrenia
    Ikwunga Wonodi
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    J Clin Psychopharmacol 24:441-5. 2004
    ..The goal of the current study was to test whether moderately high doses of naltrexone, alone or in combination with a subtherapeutic dose of a gamma aminobutyric acid agonist, improve TD...
  34. ncbi request reprint Catechol O-methyltransferase polymorphism and eye tracking in schizophrenia: a preliminary report
    Gunvant K Thaker
    MPRC, PO Box 21247, Baltimore, MD 21228, USA
    Am J Psychiatry 161:2320-2. 2004
    ..This study examined associations between functional polymorphism (Val(108/158) Met) in the catechol O-methyltransferase (COMT) gene and eye tracking measures in schizophrenia...
  35. pmc Disruption of anterior insula modulation of large-scale brain networks in schizophrenia
    Lauren V Moran
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    Biol Psychiatry 74:467-74. 2013
    ..We tested the hypothesis that right anterior insula modulation of central executive and default mode networks is disrupted in schizophrenia and associated with cognitive deficits...
  36. pmc Factor structure of the Brief Negative Symptom Scale
    Gregory P Strauss
    University of Maryland School of Medicine, Department of Psychiatry and Maryland Psychiatric Research Center, Baltimore, MD 21228, USA
    Schizophr Res 142:96-8. 2012
    ..These findings provide further support for the construct validity of the BNSS, and for the existence of these two negative symptom factors...
  37. pmc Downregulated kynurenine 3-monooxygenase gene expression and enzyme activity in schizophrenia and genetic association with schizophrenia endophenotypes
    Ikwunga Wonodi
    Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228
    Arch Gen Psychiatry 68:665-74. 2011
    ..The proximal cause may be an impairment of kynurenine 3-monooxygenase (KMO), a rate-limiting enzyme at the branching point of the kynurenine pathway...
  38. ncbi request reprint Role of anticipation in schizophrenia-related pursuit initiation deficits
    Matthew T Avila
    Maryland Psychiatric Research Ctr, PO Box 21247, Baltimore, MD 21228, USA
    J Neurophysiol 95:593-601. 2006
    ....
  39. ncbi request reprint Deficits on the Continuous Performance Test within the schizophrenia spectrum and the mediating effects of family history of schizophrenia
    Matthew T Avila
    Department of Psychiatry, University of Maryland School of Medicine, Maryland Psychiatric Research Center, Baltimore, MD 21228, USA
    J Abnorm Psychol 115:771-8. 2006
    ..Results suggest that SSPD in the absence of a family history of psychosis may be a phenocopy...
  40. pmc GABA predicts inhibition of frequency-specific oscillations in schizophrenia
    Laura M Rowland
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA
    J Neuropsychiatry Clin Neurosci 25:83-7. 2013
    ..Results revealed a strong association between GABA levels and gating of the theta-alpha and beta activities in schizophrenia...
  41. pmc Smoking and schizophrenia independently and additively reduce white matter integrity between striatum and frontal cortex
    Xiaochu Zhang
    Neuroimaging Research Branch, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland 21228, USA
    Biol Psychiatry 68:674-7. 2010
    ..We sought to determine whether smoking and schizophrenia are associated with similar white matter abnormalities that could be biomarkers for the high risk of smoking in schizophrenia...
  42. ncbi request reprint Stress-induced increase in kynurenic Acid as a potential biomarker for patients with schizophrenia and distress intolerance
    Joshua Chiappelli
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore
    JAMA Psychiatry 71:761-8. 2014
    ..The pathophysiology of schizophrenia is commonly associated with stress, and stress plays a key regulatory role in the first, rate-limiting step of the kynurenine pathway, which produces KYNA...
  43. pmc Accelerated white matter aging in schizophrenia: role of white matter blood perfusion
    Susan N Wright
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA
    Neurobiol Aging 35:2411-8. 2014
    ..The results suggest that factors other than reduced perfusion account for the accelerated age-related decline in white matter integrity in schizophrenia. ..
  44. ncbi request reprint Psychopathological and cognitive correlates of tardive dyskinesia in patients treated with neuroleptics
    Ikwunga Wonodi
    Maryland Psychiatric Research Center, Motor Disorders Clinic, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Adv Neurol 96:336-49. 2005
    ..No effective treatments for TD are available. This lack of effective therapy is problematic, especially in the few patients in whom the disorder causes functional impairment and other complications, and in whom it may be irreversible...
  45. pmc Familial aggregation of tobacco use behaviors among amish men
    Katie L Nugent
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD
    Nicotine Tob Res 16:923-30. 2014
    ..Tobacco use in the Old Order Amish community is almost exclusively confined to males...
  46. pmc Anterior cingulate GABA levels predict whole-brain cerebral blood flow
    Benjamin W Krause
    Neuroimaging Research Program, Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA
    Neurosci Lett 561:188-91. 2014
    ..We hypothesize that GABA-mediated inhibition of AC activation of the locus coeruleus-norepinephrine pathway may influence global CBF. ..
  47. pmc Individualized brain inhibition and excitation profile in response to paired-pulse TMS
    Xiaoming DU
    a Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore
    J Mot Behav 46:39-48. 2014
    ..Although the functional implications of individualized profiles are currently unknown, the relatively stable profiles may index underlying neural inhibition and excitation traits...
  48. pmc Testing the hypothesis of accelerated cerebral white matter aging in schizophrenia and major depression
    Peter Kochunov
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Biol Psychiatry 73:482-91. 2013
    ..We used diffusion tensor imaging derived fractional anisotropy (FA) as a biomarker of aging-related decline in white matter (WM) integrity to test the hypotheses of accelerated aging in SCZ and MDD...
  49. pmc Neurodevelopmental and neurodegenerative models of schizophrenia: white matter at the center stage
    Peter Kochunov
    Department of Psychiatry, Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD
    Schizophr Bull 40:721-8. 2014
    ..We argue that a combination of the cross-sectional and longitudinal studies of white matter integrity in patients may be used to bridge the neurodevelopment and degeneration heuristics to advance schizophrenia research. ..
  50. pmc Assessment of trait and state aspects of depression in schizophrenia
    Joshua Chiappelli
    To whom correspondence should be addressed Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, PO Box 21247, Baltimore, MD 21228 tel 410 402 6827, fax 410 402 6023, E mail
    Schizophr Bull 40:132-42. 2014
    ..001), but not state depression (P = .146), compared with schizophrenia patients. Trait depressive symptoms are prominent in schizophrenia and are distinct from negative symptoms...
  51. ncbi request reprint Schizophrenia, VII: defining the neurobiology of risk factors
    L Elliot Hong
    Am J Psychiatry 160:1929. 2003
  52. ncbi request reprint Association between polymorphism of the SNAP29 gene promoter region and schizophrenia
    Ikwunga Wonodi
    Schizophr Res 78:339-41. 2005

Research Grants7

  1. Liability Markers for Deficit Schizophrenia?
    L Hong; Fiscal Year: 2004
    ..We plan to use the preliminary data collected from this grant support to guide our full-scale search for phenotypic markers specifically associated with the liability for deficit schizophrenia and subsequent molecular genetic studies. ..
  2. fMRI of Eye Movement Phenotype in Schizophrenia
    L Hong; Fiscal Year: 2007
    ....
  3. Identifying molecular path of behavioural phenotype in schizophrenia
    L Hong; Fiscal Year: 2007
    ..This project aims to identify genes and gene products associated with one of these core deficits called eyetracking abnormality in schizophrenia so that drugs can be developed to treat these core physiological and cognitive deficits. ..
  4. Shared Neural Circuitry in Comorbid Schizophrenia and Nicotine Addiction
    L Elliot Hong; Fiscal Year: 2010
    ....
  5. Neural Oscillatory Biomarkers for Genetics and Animal Models of Schizophrenia
    L Elliot Hong; Fiscal Year: 2010
    ....