Jeong S Hong

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. pmc Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis
    Jennifer S Guimbellot
    Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    BMC Med Genomics 2:15. 2009
  2. pmc In vivo antitumor activity of intratumoral fludarabine phosphate in refractory tumors expressing E. coli purine nucleoside phosphorylase
    Eric J Sorscher
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Cancer Chemother Pharmacol 70:321-9. 2012
  3. ncbi request reprint Antibiotic-mediated chemoprotection enhances adaptation of E. coli PNP for herpes simplex virus-based glioma therapy
    Suman Bharara
    Department of Surgery, University of Alabama at Birmingham, AL 35294, USA
    Hum Gene Ther 16:339-47. 2005
  4. pmc S-palmitoylation regulates biogenesis of core glycosylated wild-type and F508del CFTR in a post-ER compartment
    Michelle L McClure
    Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294, U S A
    Biochem J 459:417-25. 2014
  5. ncbi request reprint Micro-RNA-like effects of complete intronic sequences
    Aubrey E Hill
    Pittman General Clinical Research Center, University of Alabama, Birmingham, Alabama 35294, USA
    Front Biosci 11:1998-2006. 2006
  6. pmc Role of oxygen availability in CFTR expression and function
    Jennifer S Guimbellot
    Department of Genetics, Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294 0005, USA
    Am J Respir Cell Mol Biol 39:514-21. 2008
  7. pmc Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications
    Michelle McClure
    Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Protein Eng Des Sel 25:7-14. 2012
  8. ncbi request reprint Excellent in vivo bystander activity of fludarabine phosphate against human glioma xenografts that express the escherichia coli purine nucleoside phosphorylase gene
    Jeong S Hong
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama 35294 0005, USA
    Cancer Res 64:6610-5. 2004
  9. pmc Thermally unstable gating of the most common cystic fibrosis mutant channel (ΔF508): "rescue" by suppressor mutations in nucleotide binding domain 1 and by constitutive mutations in the cytosolic loops
    Wei Wang
    Department of Physiology and Biophysics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Biol Chem 286:41937-48. 2011
  10. ncbi request reprint Molecular proximity of cystic fibrosis transmembrane conductance regulator and epithelial sodium channel assessed by fluorescence resonance energy transfer
    Bakhrom K Berdiev
    Department of Physiology and Biophysics, Gregory Fleming James Cystic Fibrosis Research Center, The University of Alabama at Birmingham, Birmingham, Alabama 35294 0005, USA
    J Biol Chem 282:36481-8. 2007

Collaborators

  • William B Parker
  • Wei Wang
  • Gergely L Lukacs
  • Stephen W Erickson
  • Stephen Barnes
  • Grier P Page
  • Bakhrom K Berdiev
  • Daniel F Balkovetz
  • Yiu Fai Chen
  • John P Clancy
  • James Collawn
  • Eric J Sorscher
  • Jennifer S Guimbellot
  • Hui Wen
  • Michelle L McClure
  • Michelle McClure
  • Kimberly V Curlee
  • William R Waud
  • Paula W Allan
  • Aubrey E Hill
  • Suman Bharara
  • Karoly Varga
  • Jason K Burrus
  • James Fortenberry
  • Xiaoyun Wu
  • Marjorie Ray
  • Qun Dai
  • Steven M Rowe
  • Landon Wilson
  • John C Kappes
  • Lawrence J Delucas
  • Tapan Mehta
  • Charles Venglarik
  • James A Fortenberry
  • Suzanne Oparil
  • Bryan Moore
  • Gene P Siegal
  • Sylvia A McPherson
  • Dana N Levasseur
  • David T McPherson
  • Lihong Teng
  • Sherrie A Alexander
  • J Russell Lindsey
  • V K Gadi
  • G Yancey Gillespie
  • John A Secrist
  • Zsuzsa Bebok
  • Ashutosh Niraj
  • William D Matheson
  • Marina Mazur
  • Asta Jurkuvenaite
  • John Wakefield
  • Charles J Venglarik
  • Eric Hunter
  • Michael Sakalian
  • Dale Benos
  • Maja A Sommerfelt
  • Scott A King

Detail Information

Publications13

  1. pmc Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis
    Jennifer S Guimbellot
    Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    BMC Med Genomics 2:15. 2009
    ..The methods described here for comparative analysis of cellular miRNA and mRNA will be useful for understanding genome wide regulatory responsiveness and refining miRNA predictive algorithms...
  2. pmc In vivo antitumor activity of intratumoral fludarabine phosphate in refractory tumors expressing E. coli purine nucleoside phosphorylase
    Eric J Sorscher
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Cancer Chemother Pharmacol 70:321-9. 2012
    ....
  3. ncbi request reprint Antibiotic-mediated chemoprotection enhances adaptation of E. coli PNP for herpes simplex virus-based glioma therapy
    Suman Bharara
    Department of Surgery, University of Alabama at Birmingham, AL 35294, USA
    Hum Gene Ther 16:339-47. 2005
    ..Bystander killing of the magnitude described here has been difficult to accomplish with other suicide genes, such as HSV-tk or cytosine deaminase. The results establish a model for applying E. coli PNP to HSV treatment of glioma...
  4. pmc S-palmitoylation regulates biogenesis of core glycosylated wild-type and F508del CFTR in a post-ER compartment
    Michelle L McClure
    Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294, U S A
    Biochem J 459:417-25. 2014
    ..Interestingly, immunofluorescence revealed that DHHC-7 also sequesters the F508del protein to a post-ER (Golgi) compartment. Our findings point to the importance of palmitoylation during wild-type and F508del CFTR trafficking. ..
  5. ncbi request reprint Micro-RNA-like effects of complete intronic sequences
    Aubrey E Hill
    Pittman General Clinical Research Center, University of Alabama, Birmingham, Alabama 35294, USA
    Front Biosci 11:1998-2006. 2006
    ..The results are consistent with the observation that splicesomal introns are found only in eukaryotic organisms and that the number of introns increases with phylogenetic complexity...
  6. pmc Role of oxygen availability in CFTR expression and function
    Jennifer S Guimbellot
    Department of Genetics, Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294 0005, USA
    Am J Respir Cell Mol Biol 39:514-21. 2008
    ..Environmental factors that induce hypoxic signaling regulate CFTR mRNA and epithelial Cl(-) transport in vitro and in vivo...
  7. pmc Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications
    Michelle McClure
    Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Protein Eng Des Sel 25:7-14. 2012
    ....
  8. ncbi request reprint Excellent in vivo bystander activity of fludarabine phosphate against human glioma xenografts that express the escherichia coli purine nucleoside phosphorylase gene
    Jeong S Hong
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama 35294 0005, USA
    Cancer Res 64:6610-5. 2004
    ..These findings define levels of E. coli PNP expression necessary for antitumor activity with F-araAMP and demonstrate new potential for a clinically approved compound in solid tumor therapy...
  9. pmc Thermally unstable gating of the most common cystic fibrosis mutant channel (ΔF508): "rescue" by suppressor mutations in nucleotide binding domain 1 and by constitutive mutations in the cytosolic loops
    Wei Wang
    Department of Physiology and Biophysics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Biol Chem 286:41937-48. 2011
    ....
  10. ncbi request reprint Molecular proximity of cystic fibrosis transmembrane conductance regulator and epithelial sodium channel assessed by fluorescence resonance energy transfer
    Bakhrom K Berdiev
    Department of Physiology and Biophysics, Gregory Fleming James Cystic Fibrosis Research Center, The University of Alabama at Birmingham, Birmingham, Alabama 35294 0005, USA
    J Biol Chem 282:36481-8. 2007
    ..Our results place CFTR and ENaC within reach of each other, suggestive of a direct interaction between these two proteins...
  11. ncbi request reprint Hepatocyte growth factor stimulates adenoviral-mediated gene transfer across the apical membrane of epithelial cells
    Jason K Burrus
    Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    J Gene Med 6:624-30. 2004
    ..Hepatocyte growth factor (HGF) dedifferentiates previously well-polarized Madin-Darby canine kidney (MDCK) cell monolayers by altering cell-surface polarity and inhibiting tight junction function...
  12. ncbi request reprint Efficient intracellular processing of the endogenous cystic fibrosis transmembrane conductance regulator in epithelial cell lines
    Karoly Varga
    Department of Cell Biology, Genetics and Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Biol Chem 279:22578-84. 2004
    ..Our results question the structural instability model of wild type CFTR and indicate that epithelial cells endogenously expressing CFTR efficiently process this protein to post-Golgi compartments...
  13. ncbi request reprint Membrane transplantation to correct integral membrane protein defects
    Kimberly V Curlee
    Department of Human Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    J Mol Med (Berl) 81:511-20. 2003
    ....