J Holy

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. pmc Vital imaging of H9c2 myoblasts exposed to tert-butylhydroperoxide--characterization of morphological features of cell death
    Vilma A Sardao
    Center for Neurosciences and Cellular Biology, University of Coimbra, Coimbra, Portugal
    BMC Cell Biol 8:11. 2007
  2. ncbi request reprint Curcumin inhibits cell motility and alters microfilament organization and function in prostate cancer cells
    Jon Holy
    Department of Anatomy and Cell Biology, University of Minnesota School of Medicine, Duluth, MN, USA
    Cell Motil Cytoskeleton 58:253-68. 2004
  3. ncbi request reprint Chlorpropham [isopropyl N-(3-chlorophenyl) carbamate] disrupts microtubule organization, cell division, and early development of sea urchin embryos
    J Holy
    Department of Anatomy and Cell Biology, School of Medicine, University of Minnesota, Duluth 55812 2487, USA
    J Toxicol Environ Health A 54:319-33. 1998
  4. ncbi request reprint Intermediate filament proteins in echinoderm coelomocytes
    J Holy
    Department of Anatomy and Cell Biology, School of Medicine, University of Minnesota, Duluth 55812 2487, USA
    Comp Biochem Physiol B Biochem Mol Biol 127:491-504. 2000
  5. ncbi request reprint Curcumin disrupts mitotic spindle structure and induces micronucleation in MCF-7 breast cancer cells
    Jon M Holy
    Department of Anatomy and Cell Biology, UMD School of Medicine, 10 University Drive, Duluth, MN 55812 2487, USA
    Mutat Res 518:71-84. 2002
  6. doi request reprint Dimethylaminopyridine derivatives of lupane triterpenoids are potent disruptors of mitochondrial structure and function
    Jon Holy
    Department of Anatomy, Microbiology and Pathology, University of Minnesota School of Medicine, Duluth, USA
    Bioorg Med Chem 18:6080-8. 2010
  7. doi request reprint Differentiation of pluripotent stem cells on multiwalled carbon nanotubes
    Jon Holy
    Department of Anatomy, Microbiology and Pathology, University of Minnesota School of Medicine Duluth, Duluth, MN 55812, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:6022-5. 2009
  8. pmc Disruption of nucleocytoplasmic trafficking of cyclin D1 and topoisomerase II by sanguinarine
    Jon Holy
    Department of Anatomy, Microbiology, and Pathology, University of Minnesota Medical School Duluth, MN 55812 2487, USA
    BMC Cell Biol 7:13. 2006
  9. doi request reprint Adhesion, proliferation and differentiation of pluripotent stem cells on multi-walled carbon nanotubes
    J Holy
    University of Minnesota, School of Medicine Duluth, Department of Anatomy, Microbiology and Pathology, Duluth, USA
    IET Nanobiotechnol 5:41-6. 2011
  10. ncbi request reprint Molecular characterization and expression patterns of a B-type nuclear lamin during sea urchin embryogenesis
    J Holy
    Department of Anatomy and Cell Biology, School of Medicine, University of Minnesota, Duluth 55812 2487, USA
    Dev Biol 168:464-78. 1995

Collaborators

Detail Information

Publications11

  1. pmc Vital imaging of H9c2 myoblasts exposed to tert-butylhydroperoxide--characterization of morphological features of cell death
    Vilma A Sardao
    Center for Neurosciences and Cellular Biology, University of Coimbra, Coimbra, Portugal
    BMC Cell Biol 8:11. 2007
    ..The objective of this work was to characterize, through vital imaging, morphological alterations and the appearance of apoptotic hallmarks, with a special focus on mitochondrial changes, upon exposure of H9c2 cells to tBHP...
  2. ncbi request reprint Curcumin inhibits cell motility and alters microfilament organization and function in prostate cancer cells
    Jon Holy
    Department of Anatomy and Cell Biology, University of Minnesota School of Medicine, Duluth, MN, USA
    Cell Motil Cytoskeleton 58:253-68. 2004
    ..This is a novel observation that may represent an important mechanism by which curcumin functions as a chemopreventative agent, and as an inhibitor of angiogenesis and metastasis...
  3. ncbi request reprint Chlorpropham [isopropyl N-(3-chlorophenyl) carbamate] disrupts microtubule organization, cell division, and early development of sea urchin embryos
    J Holy
    Department of Anatomy and Cell Biology, School of Medicine, University of Minnesota, Duluth 55812 2487, USA
    J Toxicol Environ Health A 54:319-33. 1998
    ....
  4. ncbi request reprint Intermediate filament proteins in echinoderm coelomocytes
    J Holy
    Department of Anatomy and Cell Biology, School of Medicine, University of Minnesota, Duluth 55812 2487, USA
    Comp Biochem Physiol B Biochem Mol Biol 127:491-504. 2000
    ....
  5. ncbi request reprint Curcumin disrupts mitotic spindle structure and induces micronucleation in MCF-7 breast cancer cells
    Jon M Holy
    Department of Anatomy and Cell Biology, UMD School of Medicine, 10 University Drive, Duluth, MN 55812 2487, USA
    Mutat Res 518:71-84. 2002
    ....
  6. doi request reprint Dimethylaminopyridine derivatives of lupane triterpenoids are potent disruptors of mitochondrial structure and function
    Jon Holy
    Department of Anatomy, Microbiology and Pathology, University of Minnesota School of Medicine, Duluth, USA
    Bioorg Med Chem 18:6080-8. 2010
    ..Thus, DMAP derivatives of lupane triterpenoids can be potent mitochondrial perturbants that appear to suppress cell growth primarily via their mitochondrial effects...
  7. doi request reprint Differentiation of pluripotent stem cells on multiwalled carbon nanotubes
    Jon Holy
    Department of Anatomy, Microbiology and Pathology, University of Minnesota School of Medicine Duluth, Duluth, MN 55812, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:6022-5. 2009
    ..The results suggest that MWNTs will be useful in directing pluripotent stem cell differentiation for tissue engineering purposes...
  8. pmc Disruption of nucleocytoplasmic trafficking of cyclin D1 and topoisomerase II by sanguinarine
    Jon Holy
    Department of Anatomy, Microbiology, and Pathology, University of Minnesota Medical School Duluth, MN 55812 2487, USA
    BMC Cell Biol 7:13. 2006
    ..To more closely examine the responses of some of these cell cycle regulatory molecules to sanguinarine, we used immunocytochemical methods to visualize cyclin D1 and topoisomerase II behavior in MCF-7 breast cancer cells...
  9. doi request reprint Adhesion, proliferation and differentiation of pluripotent stem cells on multi-walled carbon nanotubes
    J Holy
    University of Minnesota, School of Medicine Duluth, Department of Anatomy, Microbiology and Pathology, Duluth, USA
    IET Nanobiotechnol 5:41-6. 2011
    ..The results suggest that MWNTs will be useful in directing pluripotent stem cell differentiation for tissue engineering purposes...
  10. ncbi request reprint Molecular characterization and expression patterns of a B-type nuclear lamin during sea urchin embryogenesis
    J Holy
    Department of Anatomy and Cell Biology, School of Medicine, University of Minnesota, Duluth 55812 2487, USA
    Dev Biol 168:464-78. 1995
    ..These observations demonstrate that, similar to vertebrates, cell differentiation in invertebrates can be accompanied by a change in lamin expression patterns...
  11. ncbi request reprint Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: the switch between apoptosis and necrosis
    Anabela P Rolo
    Center for Neurosciences and Cell Biology of Coimbra, Department of Zoology, University of Coimbra, 3004 517 Coimbra, Portugal
    Toxicol Sci 79:196-204. 2004
    ..Consequently, as suggested by the lack of the main hallmarks of the apoptotic pathway, in the presence of UDCA, CDCA-induced apoptosis is not properly executed but degenerates into necrosis...