Research Topics
| Daniel A HoltermanSummaryAffiliation: University of Arizona Country: USA Publications
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Detail Information
Publications
Overexpression of alpha-defensin is associated with bladder cancer invasivenessDaniel A Holterman
Departments of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA 23507, USA
Urol Oncol 24:97-108. 2006..We propose that autocrine tumor expression of alpha-defensins may play an important role in facilitating the invasive phenotype of bladder cancer in patients...
Prostate tumor microenvironment alters immune cells and prevents long-term survival in an orthotopic mouse model following flt3-ligand/CD40-ligand immunotherapyRichard P Ciavarra
Departments of Microbiology and Molecular Cell Biology, Virginia Prostate Center, Eastern Virginia Medical School, Norfolk, Virginia 23501, USA
J Immunother 27:13-26. 2004..Overall, these data suggest that long-term cures of established MHC-negative tumors may not be achieved until therapeutic interventions are engineered to overcome this immunosuppressive microenvironment...
Impact of the tumor microenvironment on host infiltrating cells and the efficacy of flt3-ligand combination immunotherapy evaluated in a treatment model of mouse prostate cancerRichard P Ciavarra
Department of Microbiology, Eastern Virginia Medical School, Norfolk, VA 23501, USA
Cancer Immunol Immunother 52:535-45. 2003..These data also highlight the importance of utilizing treatment versus vaccination models in the evaluation of immunotherapeutic modalities...
Orthotopic treatment model of prostate cancer and metastasis in the immunocompetent mouse: efficacy of flt3 ligand immunotherapyKenneth D Somers
Departments of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA 23507, USA
Int J Cancer 107:773-80. 2003..We demonstrate that flt3L treatment suppressed orthotopic prostate tumor growth and lymph node metastasis reinforcing a role for flt3L as an immunotherapeutic strategy for prostate cancer...
