Daniel A Holterman

Summary

Affiliation: University of Arizona
Country: USA

Publications

  1. ncbi request reprint Overexpression of alpha-defensin is associated with bladder cancer invasiveness
    Daniel A Holterman
    Departments of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA 23507, USA
    Urol Oncol 24:97-108. 2006
  2. ncbi request reprint Prostate tumor microenvironment alters immune cells and prevents long-term survival in an orthotopic mouse model following flt3-ligand/CD40-ligand immunotherapy
    Richard P Ciavarra
    Departments of Microbiology and Molecular Cell Biology, Virginia Prostate Center, Eastern Virginia Medical School, Norfolk, Virginia 23501, USA
    J Immunother 27:13-26. 2004
  3. ncbi request reprint Impact of the tumor microenvironment on host infiltrating cells and the efficacy of flt3-ligand combination immunotherapy evaluated in a treatment model of mouse prostate cancer
    Richard P Ciavarra
    Department of Microbiology, Eastern Virginia Medical School, Norfolk, VA 23501, USA
    Cancer Immunol Immunother 52:535-45. 2003
  4. ncbi request reprint Orthotopic treatment model of prostate cancer and metastasis in the immunocompetent mouse: efficacy of flt3 ligand immunotherapy
    Kenneth D Somers
    Departments of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA 23507, USA
    Int J Cancer 107:773-80. 2003

Detail Information

Publications4

  1. ncbi request reprint Overexpression of alpha-defensin is associated with bladder cancer invasiveness
    Daniel A Holterman
    Departments of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA 23507, USA
    Urol Oncol 24:97-108. 2006
    ..We propose that autocrine tumor expression of alpha-defensins may play an important role in facilitating the invasive phenotype of bladder cancer in patients...
  2. ncbi request reprint Prostate tumor microenvironment alters immune cells and prevents long-term survival in an orthotopic mouse model following flt3-ligand/CD40-ligand immunotherapy
    Richard P Ciavarra
    Departments of Microbiology and Molecular Cell Biology, Virginia Prostate Center, Eastern Virginia Medical School, Norfolk, Virginia 23501, USA
    J Immunother 27:13-26. 2004
    ..Overall, these data suggest that long-term cures of established MHC-negative tumors may not be achieved until therapeutic interventions are engineered to overcome this immunosuppressive microenvironment...
  3. ncbi request reprint Impact of the tumor microenvironment on host infiltrating cells and the efficacy of flt3-ligand combination immunotherapy evaluated in a treatment model of mouse prostate cancer
    Richard P Ciavarra
    Department of Microbiology, Eastern Virginia Medical School, Norfolk, VA 23501, USA
    Cancer Immunol Immunother 52:535-45. 2003
    ..These data also highlight the importance of utilizing treatment versus vaccination models in the evaluation of immunotherapeutic modalities...
  4. ncbi request reprint Orthotopic treatment model of prostate cancer and metastasis in the immunocompetent mouse: efficacy of flt3 ligand immunotherapy
    Kenneth D Somers
    Departments of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA 23507, USA
    Int J Cancer 107:773-80. 2003
    ..We demonstrate that flt3L treatment suppressed orthotopic prostate tumor growth and lymph node metastasis reinforcing a role for flt3L as an immunotherapeutic strategy for prostate cancer...