Research Topics
| W C HolmesSummaryAffiliation: University of Pennsylvania Country: USA Publications
Research Grants
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Detail Information
Publications
HIV/AIDS-specific quality of life and adherence to antiretroviral therapy over timeWilliam C Holmes
Center for Health Equity Research and Promotion, Philadelphia Veterans Affairs Medical Center, Philadelphia, PA, USA
J Acquir Immune Defic Syndr 46:323-7. 2007..To determine if HIV/AIDS-specific quality of life (QOL) predicts adherence to antiretroviral therapy (ART)...- Men's childhood sexual abuse histories by one-parent versus two-parent status of childhood homeWilliam C Holmes
Center for Health Equity Research and Promotion, Philadelphia VA Medical Center, Philadelphia, PA 19104, USA
J Epidemiol Community Health 61:319-25. 2007..To estimate the association between number of parents in the childhood home and childhood sexual abuse (CSA) with adjustment for childhood socioeconomic status (CSES)... - Appropriateness of antiretroviral therapy in clients of an HIV/AIDS case management organizationW C Holmes
University of Pennsylvania School of Medicine, USA
AIDS Care 19:273-81. 2007..HIV-related knowledge appears to increase likelihood of receiving appropriate ART and it attenuates the effect of sex... - Brief communication: physical abuse of boys and possible associations with poor adult outcomesWilliam C Holmes
Philadelphia Veterans Affairs Medical Center and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6021, USA
Ann Intern Med 143:581-6. 2005..Men's childhood physical abuse experiences are understudied... - Men's pathways to risky sexual behavior: role of co-occurring childhood sexual abuse, posttraumatic stress disorder, and depression historiesWilliam C Holmes
Philadelphia Veterans Affairs Medical Center, MSCE University of Pennsylvania School of Medicine, 733 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
J Urban Health 82:i89-99. 2005.... - Test-retest evaluation of HAT-QoL and SF-36 in an HIV-seropositive sampleWilliam C Holmes
Departments of Medicine and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, USA
AIDS Care 20:1084-92. 2008..HAT-QoL reveals considerable short-term stability and has psychometric features in the seropositive population comparable to instruments such as SF-36, while obtaining unique information... - HIV-seropositive individuals' optimistic beliefs about prognosis and relation to medication and safe sex adherenceWilliam C Holmes
Philadelphia Veterans Affairs Medical Center and Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 19104 6021, USA
J Gen Intern Med 17:677-83. 2002..The study objective was to characterize respondents' prognostic perceptions of HIV infection and to explore how perceptions might affect medication and safe sex nonadherence... - Two approaches to measuring quality of life in the HIV/AIDS population: HAT-QoL and MOS-HIVW C Holmes
Division of General Internal Medicine, Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia 19104 2676, USA
Qual Life Res 8:515-27. 1999..Reduce the number of HIV/AIDS-Targeted Quality of Life (HAT-QoL) items, assess psychometric performance of the shortened HAT-QoL, and compare psychometric performance of HAT-QoL to that of Medical Outcomes study HIV Health Survey (MOS-HIV)... - Sexual abuse of boys: definition, prevalence, correlates, sequelae, and managementW C Holmes
Department of Medicine, Leonard Davis Institute, University of Pennsylvania School of Medicine and The Children s Hospital of Philadelphia, 19104 6021, USA
JAMA 280:1855-62. 1998..To clarify the definition of sexual abuse of boys, update estimates of its prevalence, and explore critically its reported correlates, sequelae, and management... - A new HIV/AIDS-targeted quality of life (HAT-QoL) instrument: development, reliability, and validityW C Holmes
Division of General Internal Medicine and the Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
Med Care 36:138-54. 1998..The objectives of this study were to identify quality-of-life concerns, as reported by human immunodeficiency virus (HIV) seropositive individuals, and to develop a measure to assess these concerns... - A short, psychiatric, case-finding measure for HIV seropositive outpatients: performance characteristics of the 5-item mental health subscale of the SF-20 in a male, seropositive sampleW C Holmes
Division of General Internal Medicine and the Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
Med Care 36:237-43. 1998.... - Men's self-definitions of abusive childhood sexual experiences, and potentially related risky behavioral and psychiatric outcomesWilliam C Holmes
Center for Health Equity Research and Promotion, Philadelphia Veterans Affairs Medical Center, University of Pennsylvania School of Medicine, Philadelphia, PA, United States
Child Abuse Negl 32:83-97. 2008.... - Childhood sexual and physical abuse histories, PTSD, depression, and HIV risk outcomes in women injection drug users: a potential mediating pathwayRosalyn E Plotzker
Center for the Studies of Addiction, HIV Prevention Division, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, USA
Am J Addict 16:431-8. 2007..01) and drug (p < 0.03) risk. After PTSD/depression adjustment, CSA was no longer associated with sexual or drug risk. These results suggest that women IDUs' CSA-to-risk path is mediated by PTSD/depression... - Contact isolation for infection control in hospitalized patients: is patient satisfaction affected?Leanne B Gasink
Division of Infectious Diseases, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
Infect Control Hosp Epidemiol 29:275-8. 2008..In multivariable analysis, isolated patients were not less satisfied with inpatient care than were nonisolated patients... - Screening male primary care patients for intimate partner violence perpetrationJeffrey R Jaeger
Division of General Internal Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Gen Intern Med 23:1152-6. 2008..Primary prevention of intimate partner violence (IPV) at the level of the primary care provider is unexplored... - Human immunodeficiency virus (HIV) infection and quality of life: the potential impact of Axis I psychiatric disorders in a sample of 95 HIV seropositive menW C Holmes
Division of General Internal Medicine, University of Pennsylvania Medical School, Philadelphia 19104 6021, USA
Psychosom Med 59:187-92. 1997..The purpose of this study is to assess whether Axis I psychiatric disorders exert effects on function and well-being independent of human immunodeficiency virus (HIV)-related disease progression... - Veterans' distress related to participation in a study about detainee abuseKatherine O Gariti
Mental Health Clinic, Philadelphia Veterans Affairs Medical Center, University and Woodland Avenues, Philadelphia, PA 19104, USA
Mil Med 174:1149-54. 2009..82, 13.90). Distress related to study participation was high in this veteran sample. Higher rates in some subgroups suggested that some individuals may not be able to accurately anticipate risk for harm in sensitive studies... - Medication beliefs as mediators of the health literacy-antiretroviral adherence relationship in HIV-infected individualsJoseph Graham
Department of Family Medicine and Community Health, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
AIDS Behav 11:385-92. 2007..Although the beliefs assessed do not mediate the relation between literacy and adherence, we identified low adherence norms as a potentially modifiable belief associated with adherence... - Availability of rapid human immunodeficiency virus testing in academic emergency departmentsPeter D Ehrenkranz
Robert Wood Johnson Clinical Scholars Program, University of Pennsylvania, Philadelphia, PA, USA
Acad Emerg Med 15:144-50. 2008..The study objectives were to determine the accessibility of rapid HIV testing in academic EDs, to identify factors that influence an ED's adoption of testing, and to describe current HIV testing practices... - Menstrual irregularity from hormonal contraception: a cause of reproductive health concerns in minority adolescent young womenLiana R Clark
Craig Dalsimer Division of Adolescent Medicine, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Contraception 74:214-9. 2006..We sought to identify teens' concerns and misperceptions about the menstrual-related side effects of HC... - Abuse of war zone detainees: veterans' perceptions of acceptabilityWilliam C Holmes
Physician, Center for Health Equity Research and Promotion, Philadelphia Veterans Affairs Medical Center, PA 19104, USA
Mil Med 172:175-81. 2007..There may be potential value to using similar scenario-based questionnaires to study active duty military perceptions of detainee abuse. Results may inform prevention policies... - Stigma and the acceptability of depression treatments among african americans and whitesJane L Givens
Boston University Medical Center, Geriatrics Section, Boston, MA 02118 2393, USA
J Gen Intern Med 22:1292-7. 2007..Stigma is associated with depression treatment, however, whether stigma differs between depression treatment modalities is not known, nor have racial differences in depression treatment stigma been fully explored... - Changes in religiousness and spirituality attributed to HIV/AIDS: are there sex and race differences?Sian Cotton
Health Services Research and Development, VA Medical Center, Cincinnati, OH, USA
J Gen Intern Med 21:S14-20. 2006..The objective of this study was (1) to describe changes in religiousness and spirituality of people with HIV/AIDS, and (2) to determine if these changes differed by sex and race... - HIV/AIDS, utilities, and cost-effectiveness analysis: stepping toward the futureWilliam C Holmes
Med Decis Making 22:522-5. 2002
Research Grants
- Surveying Men About Abuse, Risk Taking: Phone AssessmentWilliam Holmes; Fiscal Year: 2003..abstract_text> ..
- Interaction of abuse, PTSD, depression on men's sex riskWilliam Holmes; Fiscal Year: 2007..From this model, multidimensional HIV risk reduction interventions can be built. ..