Research Topics
Genomes and GenesSpecies | Alisha K HollowaySummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Genomic analysis of the relationship between gene expression variation and DNA polymorphism in Drosophila simulansMara K N Lawniczak
Division of Cell and Molecular Biology, Imperial College London, London, SW7 2AZ, UK
Genome Biol 9:R125. 2008..Addressing this question requires linking population genomic data with gene expression variation...
Rampant adaptive evolution in regions of proteins with unknown function in Drosophila simulansAlisha K Holloway
Section of Evolution and Ecology, University of California at Davis, Davis, California, United States of America
PLoS ONE 2:e1113. 2007..Non-domain regions of proteins clearly play a major role in adaptive protein evolution on a genomic scale and merit future investigations of their functional properties...
Polyploids with different origins and ancestors form a single sexual polyploid speciesAlisha K Holloway
Section of Integrative Biology, University of Texas, Austin, Texas 78712, USA
Am Nat 167:E88-101. 2006..Thus, polyploid species may have complex origins, especially in systems in which isolating mechanisms (such as advertisement calls) are affected directly through hybridization and polyploidy...
Experimental evolution of gene duplicates in a bacterial plasmid modelAlisha K Holloway
Section of Evolution and Ecology, Center for Population Biology, University of California, Davis, CA 95616, USA
J Mol Evol 64:215-22. 2007..This study highlights the importance of the cost of duplicate genes and the quantitative nature of the tradeoff in the evolution of gene duplication through functional divergence...
Adaptive gene expression divergence inferred from population genomicsAlisha K Holloway
Section of Evolution and Ecology, University of California Davis, Davis, California, USA
PLoS Genet 3:2007-13. 2007..Our results provide a genomic view of the intimate link between selection acting on a phenotype and associated genic evolution...
Accelerated sequence divergence of conserved genomic elements in Drosophila melanogasterAlisha K Holloway
Department of Evolution and Ecology and Center for Population Biology, University of California, Davis, California 95691, USA
Genome Res 18:1592-601. 2008..Our analysis also highlights interesting noncoding genomic regions, such as regulatory regions in the gene gooseberry-neuro and a putative novel miRNA...
Population genomics: whole-genome analysis of polymorphism and divergence in Drosophila simulansDavid J Begun
Department of Evolution and Ecology, University of California Davis, Davis, California, United States of America
PLoS Biol 5:e310. 2007..simulans...
Pervasive and largely lineage-specific adaptive protein evolution in the dosage compensation complex of Drosophila melanogasterMia T Levine
Section of Evolution and Ecology, University of California, Davis, California 95616, USA
Genetics 177:1959-62. 2007..melanogaster. Within these four proteins, several domains that range in function from X chromosome localization to protein-protein interactions have elevated, D. melanogaster-specific, amino acid divergence...
Genomic variation in natural populations of Drosophila melanogasterCharles H Langley
Department of Evolution and Ecology, University of California, Davis, CA 95616, USA
Genetics 192:533-98. 2012..Comparison of the variation among these genomes to variation among genomes from D. simulans suggests that many targets of directional selection are shared between these species...
Recently evolved genes identified from Drosophila yakuba and D. erecta accessory gland expressed sequence tagsDavid J Begun
Section of Evolution and Ecology, University of California, Davis, California 95616, USA
Genetics 172:1675-81. 2006..We found no evidence that these novel genes are attributable primarily to duplication and divergence, which suggests the possibility that Acp's or other genes coding for small proteins may originate from ancestrally noncoding DNA...
Molecular evolution and population genetics of duplicated accessory gland protein genes in DrosophilaAlisha K Holloway
Mol Biol Evol 21:1625-8. 2004..These data support the idea that selection on reproduction-related genes may drive divergence of populations within species, and strengthen the conclusion that Acps may often be under directional selection in Drosophila...
