Research Topics
| William HollingworthSummaryAffiliation: University of Washington Country: USA Publications
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Detail Information
Publications
The ProActive trial protocol - a randomised controlled trial of the efficacy of a family-based, domiciliary intervention programme to increase physical activity among individuals at high risk of diabetes [ISRCTN61323766]Kate Williams
General Practice and Primary Care Research Unit, Department of Public Health and Primary Care, Institute of Public Health, Forvie Site, Robinson Way, Cambridge CB2 2SR, UK
BMC Public Health 4:48. 2004..While previous evaluations of interventions to increase physical activity have involved communities or individuals with established disease, less attention has been given to interventions for individuals at risk of disease...- Randomized clinical trial of surgery versus conservative therapy for carpal tunnel syndrome [ISRCTN84286481]Brook I Martin
Department of Medicine, Division of General Internal Medicine, Multidisciplinary Clinical Research Center, Box 359736, 325 Ninth Ave Seattle, Washington 98104, USA
BMC Musculoskelet Disord 6:2. 2005..There is an increasing interest in the usefulness of wrist magnetic resonance imaging could play in predicting who will benefit for various treatments... 
Radiology cost and outcomes studies: standard practice and emerging methodsWilliam Hollingworth
Department of Radiology, University of Washington, Harborview Medical Center, 325 Ninth Ave, Box 359960, Seattle, WA 98104, USA
AJR Am J Roentgenol 185:833-9. 2005- The impact of e-prescribing on prescriber and staff time in ambulatory care clinics: a time motion studyWilliam Hollingworth
Department of Radiology, University of Washington, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
J Am Med Inform Assoc 14:722-30. 2007..4 minutes/hour; 0.0, 10.7 CI). E-prescribing was not associated with an increase in combined computer and writing time for prescribers. If carefully implemented, e-prescribing will not greatly disrupt workflow... - Prevention of deaths from harmful drinking in the United States: the potential effects of tax increases and advertising bans on young drinkersWilliam Hollingworth
Harborview Injury Prevention and Research Center, Box 359960, 325 Ninth Avenue, Seattle, Washington 98104 2499, USA
J Stud Alcohol 67:300-8. 2006..In this study, we estimate the impact of interventions to reduce the prevalence of drinking among youth on subsequent drinking patterns and alcohol-attributable mortality... - Evidence on the effectiveness and cost-effectiveness of vertebroplasty: A review of policy makers' responsesWilliam Hollingworth
Department of Radiology, Harborview Medical Center, University of Washington, Box 359960, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
Acad Radiol 13:550-5. 2006..Policy makers' reimbursement decisions for vertebroplasty and their options when faced with imperfect evidence are discussed... - Interrater reliability in assessing quality of diagnostic accuracy studies using the QUADAS tool. A preliminary assessmentWilliam Hollingworth
Department of Radiology, Box 359960, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
Acad Radiol 13:803-10. 2006..We used data from a systematic review of magnetic resonance spectroscopy (MRS) in the characterization of suspected brain tumors to provide a preliminary evaluation of the inter-rater reliability of QUADAS... - A systematic literature review of magnetic resonance spectroscopy for the characterization of brain tumorsW Hollingworth
Department of Radiology, University of Washington, 325 Ninth Avenue, Seattle, WA 98104, USA
AJNR Am J Neuroradiol 27:1404-11. 2006..Proton MR spectroscopy ((1)H-MR spectroscopy) is a potentially useful adjunct to anatomic MR imaging in the characterization of brain tumors. We performed an updated systematic review of the evidence... - Technology assessment in radiology: putting the evidence in evidence-based radiologyWilliam Hollingworth
Department of Radiology, University of Washington, Box 359960, 325 Ninth Ave, Seattle, WA 98104 2499, USA
Radiology 244:31-8. 2007..Some of the improvements in the pool of evidence during the past 30 years are documented, and some of the remaining tensions between TA and EBR are highlighted... - The use of repeated head computed tomography in pediatric blunt head trauma: factors predicting new and worsening brain injuryWilliam Hollingworth
Department of Radiology, University of Washington, Seattle, WA, USA
Pediatr Crit Care Med 8:348-56; CEU quiz 357. 2007..This study describes the prevalence of worsening brain injury on repeat computed tomography, predictors of worsening computed tomography findings, and the frequency of neurosurgical intervention after the repeat computed tomography... - The diagnostic accuracy of computed tomography angiography for traumatic or atherosclerotic lesions of the carotid and vertebral arteries: a systematic reviewWilliam Hollingworth
Department of Radiology, Harborview Medical Center and the University of Washington, Box 359728, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
Eur J Radiol 48:88-102. 2003..We conducted a systematic literature review to determine the diagnostic accuracy of CTA for atherosclerotic, penetrating and blunt lesions in the carotid and vertebral arteries... - Rapid magnetic resonance imaging for diagnosing cancer-related low back painWilliam Hollingworth
Departments of Radiology, University of Washington, Seattle, Wash 98103, USA
J Gen Intern Med 18:303-12. 2003..This study compared the relative efficiency of lumbar x-ray and rapid magnetic resonance (MR) imaging for diagnosing cancer-related low back pain (LBP) in primary care patients... - Emerging methods in economic modeling of imaging costs and outcomes a short report on discrete event simulationWilliam Hollingworth
Department of Radiology, University of Washington, Box 359960, 325 9th Avenue, Seattle, WA 98104 2499, USA
Acad Radiol 14:406-10. 2007..This short report provides a non-technical overview of one emerging modeling technique, discrete event simulation (DES)... - A randomized trial of vertebroplasty for osteoporotic spinal fracturesDavid F Kallmes
Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
N Engl J Med 361:569-79. 2009..Vertebroplasty is commonly used to treat painful, osteoporotic vertebral compression fractures... - Personal bankruptcy after traumatic brain or spinal cord injury: the role of medical debtAnnemarie Relyea-Chew
Department of Radiology, University of Washington, Seattle, WA, USA
Arch Phys Med Rehabil 90:413-9. 2009..To estimate the prevalence of medical debt among traumatic brain injury (TBI) and spinal cord injury (SCI) patients who discharged their debts through bankruptcy... 
Expenditures and health status among adults with back and neck problemsBrook I Martin
Department of Orthopaedics and Sports Medicine, University of Washington, Seattle, WA 98104, USA
JAMA 299:656-64. 2008..Back and neck problems are among the symptoms most commonly encountered in clinical practice. However, few studies have examined national trends in expenditures for back and neck problems or related these trends to health status measures...- The cost-effectiveness of the management of acute sinusitisYoshimi Anzai
Department of Radiology, University of Washington, Seattle 98195 7115, USA
Am J Rhinol 21:444-51. 2007..Sinusitis is a common medical disease with a tremendous economic impact on health care. Our objective was to determine the most cost-effective strategy for the management of acute sinusitis from the societal and payers' perspectives... - Sixteen-slice CT angiography in patients with suspected blunt carotid and vertebral artery injuriesGarth H Utter
Department of Surgery, Harborview Medical Center/University of Washington, Seattle, WA, USA
J Am Coll Surg 203:838-48. 2006..Radiologists should maintain a high degree of suspicion in patients who meet screening criteria. Optimal imaging strategies should focus on the most predictive criteria... - Surgery versus non-surgical therapy for carpal tunnel syndrome: a randomised parallel-group trialJeffrey G Jarvik
Department of Radiology, School of Medicine, University of Washington, Seattle, WA, USA
Lancet 374:1074-81. 2009..Our aim was to compare surgical versus multi-modality, non-surgical treatment for patients with carpal tunnel syndrome without denervation. We hypothesised that surgery would result in improved functional and symptom outcomes... - INvestigational Vertebroplasty Efficacy and Safety Trial (INVEST): a randomized controlled trial of percutaneous vertebroplastyLeigh A Gray
Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN, USA
BMC Musculoskelet Disord 8:126. 2007..Spine X-rays will be obtained at the end of the study (month 12) to determine subsequent fracture rates. Our co-primary outcomes are the modified Roland score and pain numerical rating scale at 1 month... - Conventional radiography, rapid MR imaging, and conventional MR imaging for low back pain: activity-based costs and reimbursementDarryl T Gray
Department of Pediatrics, School of Medicine, University of Washington, 146 N Canal St, Suite 300, Seattle, WA 98103, USA
Radiology 227:669-80. 2003..To incorporate personnel and equipment use time in an activity-based cost comparison of conventional radiography and conventional and rapid magnetic resonance (MR) imaging for low back pain (LBP)... - Electronic prescribing at the point of care: a time-motion study in the primary care settingEmily Beth Devine
Biomedical and Health Informatics, School of Medicine, University of Washington, Seattle, WA
Health Serv Res 45:152-71. 2010..Two primary aims were to compare prescribing time between (1) handwritten and electronic (e-) prescriptions and (2) e-prescriptions using differing hardware configurations... - Rapid magnetic resonance imaging vs radiographs for patients with low back pain: a randomized controlled trialJeffrey G Jarvik
Department of Radiology, University of Washington, Seattle, Wash 98195, USA
JAMA 289:2810-8. 2003.... - Spinal cord stimulation for failed back surgery syndrome: outcomes in a workers' compensation settingJudith A Turner
Department of Psychiatry and Behavioral Sciences and Department of Rehabilitation Medicine, University of Washington, 1959 NE Pacific St, Room BB1517a, Box 356560, Seattle, WA 98195 6560, USA
Pain 148:14-25. 2010..Both trial and permanent SCS were associated with adverse events. In sum, we found no evidence for greater effectiveness of SCS versus alternative treatments in this patient population after 6 months... - Characterization of prescribing errors in an internal medicine clinicEmily Beth Devine
Department of Pharmacy, University of Washington UW, Seattle, WA 98195 7630, USA
Am J Health Syst Pharm 64:1062-70. 2007.... - Radiation exposure from pediatric head CT: a bi-institutional studyMary A King
Department of Pediatrics, Harborview Medical Center, University of Washington, Seattle, WA 98104, USA
Pediatr Radiol 39:1059-65. 2009..Medical radiation from CT should be kept as low as reasonably achievable (ALARA), particularly in young patients... - Screening for blunt cerebrovascular injury: evaluating the accuracy of multidetector computed tomographic angiographyLawrence D Bub
Department of Radiology, University of Washington Medical Center, Seattle, Washington, USA
J Trauma 59:691-7. 2005.... - Costs and cost-effectiveness of spinal cord stimulation (SCS) for failed back surgery syndrome: an observational study in a workers' compensation populationWilliam Hollingworth
Department of Social Medicine, University of Bristol, Bristol, England
Spine (Phila Pa 1976) 36:2076-83. 2011..Prospective cohort study... - Comparative effectiveness research and policy: experiences conducting a coverage with evidence development study of a therapeutic deviceJudith A Turner
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA 98195 6560, USA
Med Care 48:S129-36. 2010..Between the end of subject enrollment and availability of final study results, a second SCS cohort (n = 30) was followed for 12 months... - The relationship between electrodiagnostic findings and patient symptoms and function in carpal tunnel syndromeLeighton Chan
Department of Rehabilitation Medicine, University of Washington, Seattle, WA, USA
Arch Phys Med Rehabil 88:19-24. 2007.... - Three-year incidence of low back pain in an initially asymptomatic cohort: clinical and imaging risk factorsJeffrey G Jarvik
Department of Radiology, University of Washington, Seattle, Washington 98195, USA
Spine (Phila Pa 1976) 30:1541-8; discussion 1549. 2005..Prospective cohort study of randomly selected Veterans Affairs out-patients without baseline low back pain (LBP)... - Hospital costs associated with pediatric burn injuryMatthew B Klein
Burn Center, Harborview Medical Center, University of Washington, Seattle, Washington 98104, USA
J Burn Care Res 29:632-7. 2008..Further studies defining the long-term societal costs impact of burn injury are needed as are studies that evaluate the impact of burn injury on quality of life... - The risk of bankruptcy before and after brain or spinal cord injury: a glimpse of the iceberg's tipWilliam Hollingworth
Department of Radiology, University of Washington, Seattle, WA 98104 2499, USA
Med Care 45:702-11. 2007..Injury and illness are often cited as causes of bankruptcy. However, the incidence of bankruptcy after an acute medical event is unknown... - VERTOS: A Step in the Right DirectionJeffrey G Jarvik
Department of Radiology, University of Washington, Seattle, Washington, USA
AJNR Am J Neuroradiol 28:561-2. 2007 - Innovation in diagnostic imaging services: assessing the potential for value-based reimbursementLouis P Garrison
Department of Pharmacy, University of Washington, Seattle, USA
Acad Radiol 18:1109-14. 2011..The authors examine how and whether value-based reimbursement for diagnostic imaging services might better reward innovation explicitly for expected improvements in health and economic outcomes... - Indeterminate CT angiography in blunt thoracic trauma: is CT angiography enough?Marla Sammer
Department of Radiology, University of Washington, Box 357115, Seattle, WA 98195 7115, USA
AJR Am J Roentgenol 189:603-8. 2007..The secondary objective was to devise a classification scheme for mediastinal hematomas... - Preference values associated with stage III colon cancer and adjuvant chemotherapyJennie H Best
University of Washington, Seattle, WA, USA
Qual Life Res 19:391-400. 2010..To elicit preference values for health states associated with Stage III colon cancer (CRC) and to explore the effect of neuropathy associated with current adjuvant treatment... - Utility of repeat head computed tomography after blunt head trauma: a systematic reviewMarjorie C Wang
Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
J Trauma 61:226-33. 2006..We systematically reviewed the literature to determine the incidence of progression of injury on repeat CT and resulting treatment changes... - Healthcare costs associated with mild traumatic brain injury and psychological distress in children and adolescentsCarol M Rockhill
Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98195 6560, USA
Brain Inj 24:1051-60. 2010..Comparison of healthcare costs for youth with mild traumatic brain injuries (TBIs) to costs in a matched cohort of children without TBI in the 3 years following injury... - Cost-effectiveness of a smoking cessation program implemented at the time of surgery for lung cancerChristopher G Slatore
Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle, Washington, USA
J Thorac Oncol 4:499-504. 2009..Perioperative smoking cessation is associated with improved survival, but the cost-effectiveness of a smoking cessation program initiated immediately before surgery is unknown... - The association between bankruptcy and hospital-presenting attempted suicide: a record linkage studyJudi Kidger
School of Social and Community Medicine, University of Bristol, Bristol, UK
Suicide Life Threat Behav 41:676-84. 2011.... - The practicality and validity of directly elicited and SF-36 derived health state preferences in patients with low back painWilliam Hollingworth
Department of Public Health and Primary Care, University of Cambridge, Robinson Way, Cambridge, CB2 2SR, UK
Health Econ 11:71-85. 2002..This emphasises the need for a standardised algorithm for deriving SF-36 preference scores... - Cost-effectiveness of diagnostic strategies prior to carotid endarterectomyJean Marie U-King-Im
Department of Radiology, Addenbrooke's Hospital and the University of Cambridge, Cambridge, United Kingdom
Ann Neurol 58:506-15. 2005..DUS, with additional imaging in the form of CEMRA, is recommended, with a strategy of "CEMRA and selective DUS review" being shown to be the optimal imaging strategy... - Thoracic and lumbar vertebroplasties performed in US Medicare enrollees, 2001-2005Darryl T Gray
JAMA 298:1760-2. 2007 - Measuring carotid stenosis on contrast-enhanced magnetic resonance angiography: diagnostic performance and reproducibility of 3 different methodsJean Marie K S U-King-Im
University Department of Radiology, Addenbrooke's Hospital, Cambridge, United Kingdom
Stroke 35:2083-8. 2004..All 3 methods are adequate for use with DSA. With CEMRA, however, this study supports use of the NASCET method because of improved sensitivity for detecting severe stenosis... - Evaluation of carotid stenosis with axial high-resolution black-blood MR imagingJean M U-King-Im
University Department of Radiology, Addenbrooke's Hospital, Cambridge, CB2 2QQ, UK
Eur Radiol 14:1154-61. 2004..Axial imaging with BB MRI could potentially be used to provide useful information about severity of carotid stenosis... - Contrast-enhanced MR angiography vs intra-arterial digital subtraction angiography for carotid imaging: activity-based cost analysisJean Marie U-King-Im
University Department of Radiology, Addenbrooke's Hospital, Cambridge, CB2 2QQ, UK
Eur Radiol 14:730-5. 2004..Assuming equal diagnostic performance, institutions may have substantial cost savings if CE MRA is used instead of DSA for carotid imaging... - Comparison of directly elicited preferences to preferences derived from the SF-36 in adults with asthmaTodd A Lee
Midwest Center for Health Services and Policy Research, Hines VA Hospital, P O Box 5000 151 H, Hines, IL 60141, USA
Med Decis Making 23:323-34. 2003..Algorithms have been developed that estimate preferences from the Short Form 36 (SF-36). The objective of this study was to compare SF-36-derived preferences to directly elicited preferences... - Primary care referrals for lumbar spine radiography: diagnostic yield and clinical guidelinesWilliam Hollingworth
Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge
Br J Gen Pract 52:475-80. 2002..Trial evidence suggests that guidelines can reduce radiography referrals. It is not clear whether this reduction has been achieved in routine practice...