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Genomes and Genes | L S HollidaySummaryAffiliation: University of Florida Country: USA Publications
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Publications
The amino-terminal domain of the B subunit of vacuolar H+-ATPase contains a filamentous actin binding siteL S Holliday
Departments of Medicine and Anatomy and Cell Biology, University of Florida College of Medicine, Gainesville, Florida 32610, USA
J Biol Chem 275:32331-7. 2000..In summary, binding sites for F-actin are present in the amino-terminal domains of both isoforms of the B subunit, and likely are responsible for the interaction between V-ATPase and actin filaments in vivo...
Effects of matrix metalloproteinase inhibitors on bone resorption and orthodontic tooth movementL S Holliday
Department of Orthodontics, College of Dentistry, University of Florida, Box 100444, JHMHC, Gainesville, FL 32610-0444, USA
J Dent Res 82:687-91. 2003..This study shows that orthodontic tooth movement can be inhibited with the use of matrix metalloproteinase inhibitors, and suggests a mechanistic link between matrix metalloproteinase activity and the production of RGD peptides...
Interaction between aldolase and vacuolar H+-ATPase: evidence for direct coupling of glycolysis to the ATP-hydrolyzing proton pumpM Lu
Departments of Medicine and Anatomy and Cell Biology, University of Florida College of Medicine, Gainesville, Florida 32610, USA
J Biol Chem 276:30407-13. 2001..The direct binding interaction between V-ATPase and aldolase may be a new mechanism for the regulation of the V-ATPase and may underlie the proximal tubule acidification defect in hereditary fructose intolerance...
Osteoclast polarization and orthodontic tooth movementL S Holliday
Department of Orthodontics, University of Florida College of Dentistry, Gainesville, Florida 32610, USA
Orthod Craniofac Res 12:105-12. 2009..One potential use of such agents is to block tooth movement in spatially discrete locations to provide orthodontic anchorage...
Interstitial collagenase activity stimulates the formation of actin rings and ruffled membranes in mouse marrow osteoclastsL S Holliday
Department of Orthodontics, University of Florida College of Dentistry, Gainesville, FL 32610, USA
Calcif Tissue Int 72:206-14. 2003..These data support the hypothesis that cleaved collagen stimulates osteoclastic bone resorption by triggering cytoskeletal reorganization and transport of V-ATPase from cytoplasmic stores to ruffled membranes...
In vitro and in vivo evidence for stimulation of bone resorption by an EP4 receptor agonist and basic fibroblast growth factor: Implications for their efficacy as bone anabolic agentsM E Downey
Department of Physiological Sciences, University of Florida, PO Box 100144, JHMHC, Gainesville, FL 32610 0144, USA
Bone 44:266-74. 2009....
Nuclear factor kappaB p65 phosphorylation in orthodontic tooth movementJ Zuo
Department of Orthodontics, 1600 SW Archer Road, Campus Box 100444, University of Florida College of Dentistry, Gainesville, FL 32610, USA
J Dent Res 86:556-9. 2007..We conclude that p65*(536) is produced rapidly in response to orthodontic stimuli and mechanical insults, and may be important in bone remodeling associated with orthodontic tooth movement...
Effects of echistatin and an RGD peptide on orthodontic tooth movementC Dolce
Department of Orthodontics, College of Dentistry, University of Florida, Box 100444, JHMHC, Gainesville, FL 32610 0444, USA
J Dent Res 82:682-6. 2003..01). The RGD peptide also reduced molar drift (p < 0.05). This study shows the feasibility of using ELVAX to deliver integrin inhibitors adjacent to teeth to limit local tooth movement in response to orthodontic forces...
Differential localization of myosin II isoforms in resting and activated osteoclastsI Krits
Renal Division, Washington University School of Medicine, St Louis, MO 63110, USA
Calcif Tissue Int 71:530-8. 2002..These results suggest that myosin IIA is critical to development of an activated osteoclast phenotype...
Initiation of osteoclast bone resorption by interstitial collagenaseL S Holliday
Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
J Biol Chem 272:22053-8. 1997..These results indicate that interstitial collagenase can function as a "coupling factor," allowing osteoblasts to initiate bone resorption by generating collagen fragments that activate osteoclasts...
Osteoclasts express the B2 isoform of vacuolar H(+)-ATPase intracellularly and on their plasma membranesB S Lee
Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
Am J Physiol 270:C382-8. 1996..These results indicate that V-ATPases containing the B2 subunit isoform mediate osteoclast bone resorption...
