Michael D Hoffman

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. doi request reprint Emulating native periosteum cell population and subsequent paracrine factor production to promote tissue engineered periosteum-mediated allograft healing
    Michael D Hoffman
    University of Rochester, Department of Biomedical Engineering, 207 Robert B Goergen Hall, Box 270168, Rochester, NY 14627 0168, USA University of Rochester Medical Center, Center for Musculoskeletal Research, 207 Robert B Goergen Hall, Box 270168, Rochester, NY 14627 0168, USA Electronic address
    Biomaterials 52:426-40. 2015
  2. pmc The effect of mesenchymal stem cells delivered via hydrogel-based tissue engineered periosteum on bone allograft healing
    Michael D Hoffman
    University of Rochester, Department of Biomedical Engineering, Rochester, NY, USA
    Biomaterials 34:8887-98. 2013
  3. pmc Emerging ideas: Engineering the periosteum: revitalizing allografts by mimicking autograft healing
    Michael D Hoffman
    Department of Biomedical Engineering, University of Rochester, Rochester, NY 14627 0168, USA
    Clin Orthop Relat Res 471:721-6. 2013
  4. pmc Disruption of cell-cell contact-mediated notch signaling via hydrogel encapsulation reduces mesenchymal stem cell chondrogenic potential: winner of the Society for Biomaterials Student Award in the Undergraduate Category, Charlotte, NC, April 15 to 18, 20
    Amanda X Chen
    Department of Biomedical Engineering, University of Rochester, 207 Robert B Goergen Hall, Box 270168, Rochester, New York, 14627 0168
    J Biomed Mater Res A 103:1291-302. 2015
  5. pmc Degradable hydrogels for spatiotemporal control of mesenchymal stem cells localized at decellularized bone allografts
    Michael D Hoffman
    University of Rochester, Department of Biomedical Engineering, University of Rochester, 207 Robert B Goergen Hall, Box 270168, Rochester, NY 14627 0168, USA University of Rochester, Department of Orthopaedics and Center for Musculoskeletal Research, University of Rochester Medical Center, 207 Robert B Goergen Hall, Box 270168, Rochester, NY 14627 0168, USA
    Acta Biomater 10:3431-41. 2014
  6. pmc Agonism of Wnt-β-catenin signalling promotes mesenchymal stem cell (MSC) expansion
    Michael D Hoffman
    Departments of Biomedical Engineering, Chemical Engineering and Orthopaedics and Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA
    J Tissue Eng Regen Med . 2013

Collaborators

Detail Information

Publications6

  1. doi request reprint Emulating native periosteum cell population and subsequent paracrine factor production to promote tissue engineered periosteum-mediated allograft healing
    Michael D Hoffman
    University of Rochester, Department of Biomedical Engineering, 207 Robert B Goergen Hall, Box 270168, Rochester, NY 14627 0168, USA University of Rochester Medical Center, Center for Musculoskeletal Research, 207 Robert B Goergen Hall, Box 270168, Rochester, NY 14627 0168, USA Electronic address
    Biomaterials 52:426-40. 2015
    ....
  2. pmc The effect of mesenchymal stem cells delivered via hydrogel-based tissue engineered periosteum on bone allograft healing
    Michael D Hoffman
    University of Rochester, Department of Biomedical Engineering, Rochester, NY, USA
    Biomaterials 34:8887-98. 2013
    ..However, this bottom-up biomaterials approach, the engineered periosteum, can be augmented with alternative cell types, matrix cues, growth factors, and/or other small molecule drugs to expedite the process of ossification. ..
  3. pmc Emerging ideas: Engineering the periosteum: revitalizing allografts by mimicking autograft healing
    Michael D Hoffman
    Department of Biomedical Engineering, University of Rochester, Rochester, NY 14627 0168, USA
    Clin Orthop Relat Res 471:721-6. 2013
    ..Allograft healing is inferior to autografts where the periosteum orchestrates remodeling...
  4. pmc Disruption of cell-cell contact-mediated notch signaling via hydrogel encapsulation reduces mesenchymal stem cell chondrogenic potential: winner of the Society for Biomaterials Student Award in the Undergraduate Category, Charlotte, NC, April 15 to 18, 20
    Amanda X Chen
    Department of Biomedical Engineering, University of Rochester, 207 Robert B Goergen Hall, Box 270168, Rochester, New York, 14627 0168
    J Biomed Mater Res A 103:1291-302. 2015
    ..Taken together, these findings support that cellular condensation, and establishment of initial cell-cell contacts is critical for MSC chondrogenesis, and this process is inhibited by hydrogel encapsulation...
  5. pmc Degradable hydrogels for spatiotemporal control of mesenchymal stem cells localized at decellularized bone allografts
    Michael D Hoffman
    University of Rochester, Department of Biomedical Engineering, University of Rochester, 207 Robert B Goergen Hall, Box 270168, Rochester, NY 14627 0168, USA University of Rochester, Department of Orthopaedics and Center for Musculoskeletal Research, University of Rochester Medical Center, 207 Robert B Goergen Hall, Box 270168, Rochester, NY 14627 0168, USA
    Acta Biomater 10:3431-41. 2014
    ..This work demonstrates the therapeutic utility of PEG-based hydrogels for controlling spatiotemporal cell transplantation for a myriad of regenerative medicine strategies. ..
  6. pmc Agonism of Wnt-β-catenin signalling promotes mesenchymal stem cell (MSC) expansion
    Michael D Hoffman
    Departments of Biomedical Engineering, Chemical Engineering and Orthopaedics and Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA
    J Tissue Eng Regen Med . 2013
    ..Taken together, our results demonstrate BIO's potential utility as a proliferative agent for cell transplantation and tissue regeneration. Copyright © 2013 John Wiley & Sons, Ltd...