Israel Hodish

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. ncbi Location of ectopic adrenocortical hormone-secreting tumors causing Cushing's syndrome in the paranasal sinuses
    Israel Hodish
    Department of Internal Medicine, Division of Metabolism, Endocrinology and Diabetes, University of Michigan, Ann Arbor, MI 48109, USA
    Head Neck 31:699-706. 2009
  2. ncbi In vivo misfolding of proinsulin below the threshold of frank diabetes
    Israel Hodish
    Division of Metabolism, Endocrinology, and Diabetes, University of Michigan Medical Center, Ann Arbor, Michigan, USA
    Diabetes 60:2092-101. 2011
  3. ncbi Misfolded proinsulin affects bystander proinsulin in neonatal diabetes
    Israel Hodish
    Division of Metabolism, Endocrinology, and Diabetes, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0678, USA
    J Biol Chem 285:685-94. 2010
  4. ncbi Proinsulin misfolding and diabetes: mutant INS gene-induced diabetes of youth
    Ming Liu
    Division of Metabolism, Endocrinology and Diabetes, University of Michigan Medical Center, Ann Arbor, MI, USA
    Trends Endocrinol Metab 21:652-9. 2010
  5. ncbi Frequent insulin dosage adjustments based on glucose readings alone are sufficient for a safe and effective therapy
    Eran Bashan
    Hygieia, Inc, Ann Arbor, MI, USA
    J Diabetes Complications 26:230-6. 2012
  6. ncbi The effort required to achieve and maintain optimal glycemic control
    Elyse S Rosenthal
    University of Michigan, College of Literature, Arts and Sciences, Ann Arbor, MI, USA
    J Diabetes Complications 25:283-8. 2011
  7. ncbi Proinsulin maturation, misfolding, and proteotoxicity
    Ming Liu
    Division of Metabolism, Endocrinology, and Diabetes, University of Michigan Medical Center, Ann Arbor, MI 48109, USA
    Proc Natl Acad Sci U S A 104:15841-6. 2007
  8. ncbi Are glucose readings sufficient to adjust insulin dosage?
    Eran Bashan
    Hygieia, Inc, Ann Arbor, Michigan, USA
    Diabetes Technol Ther 13:85-92. 2011

Research Grants

  1. A Novel Tool to Understand Insulin Production and Failure in Pancreatic beta-Cell
    Israel Hodish; Fiscal Year: 2007

Collaborators

Detail Information

Publications8

  1. ncbi Location of ectopic adrenocortical hormone-secreting tumors causing Cushing's syndrome in the paranasal sinuses
    Israel Hodish
    Department of Internal Medicine, Division of Metabolism, Endocrinology and Diabetes, University of Michigan, Ann Arbor, MI 48109, USA
    Head Neck 31:699-706. 2009
    ..The majority of ectopic adrenocorticotropic hormone (ACTH)-secreting tumors are localized in the chest or abdomen. Occasionally, these tumors are found in the paranasal sinuses...
  2. ncbi In vivo misfolding of proinsulin below the threshold of frank diabetes
    Israel Hodish
    Division of Metabolism, Endocrinology, and Diabetes, University of Michigan Medical Center, Ann Arbor, Michigan, USA
    Diabetes 60:2092-101. 2011
    ..Herein we have compared two mouse models expressing equally small amounts of transgenic proinsulin in pancreatic β-cells...
  3. ncbi Misfolded proinsulin affects bystander proinsulin in neonatal diabetes
    Israel Hodish
    Division of Metabolism, Endocrinology, and Diabetes, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0678, USA
    J Biol Chem 285:685-94. 2010
    ..The data support that misfolded proinsulin perturbs bystander proinsulin in the endoplasmic reticulum, leading to beta-cell failure...
  4. ncbi Proinsulin misfolding and diabetes: mutant INS gene-induced diabetes of youth
    Ming Liu
    Division of Metabolism, Endocrinology and Diabetes, University of Michigan Medical Center, Ann Arbor, MI, USA
    Trends Endocrinol Metab 21:652-9. 2010
    ..Accumulated evidence indicates that, in the molecular pathogenesis of the disease, misfolded proinsulin exerts dominant effects that initially inhibit insulin production, progressing to beta cell demise with diabetes...
  5. ncbi Frequent insulin dosage adjustments based on glucose readings alone are sufficient for a safe and effective therapy
    Eran Bashan
    Hygieia, Inc, Ann Arbor, MI, USA
    J Diabetes Complications 26:230-6. 2012
    ..We hypothesize that glucose readings are sufficient to adjust insulin dosage provided that it is done on a weekly basis...
  6. ncbi The effort required to achieve and maintain optimal glycemic control
    Elyse S Rosenthal
    University of Michigan, College of Literature, Arts and Sciences, Ann Arbor, MI, USA
    J Diabetes Complications 25:283-8. 2011
    ..Insulin therapy is most effective when dosage is frequently adjusted. We sought to evaluate the effort required to maintain A1C below 7% once attained in older patients with type 2 diabetes...
  7. ncbi Proinsulin maturation, misfolding, and proteotoxicity
    Ming Liu
    Division of Metabolism, Endocrinology, and Diabetes, University of Michigan Medical Center, Ann Arbor, MI 48109, USA
    Proc Natl Acad Sci U S A 104:15841-6. 2007
    ..The data imply that PI misfolding leading to impaired endoplasmic reticulum exit of nonmutant PI may be a key early step in a chain reaction of beta cell dysfunction and demise leading to onset and progression of diabetes...
  8. ncbi Are glucose readings sufficient to adjust insulin dosage?
    Eran Bashan
    Hygieia, Inc, Ann Arbor, Michigan, USA
    Diabetes Technol Ther 13:85-92. 2011
    ..We hypothesize that glucose readings are sufficient to adjust insulin dosage provided that dosage is adjusted every 1-4 weeks...

Research Grants2

  1. A Novel Tool to Understand Insulin Production and Failure in Pancreatic beta-Cell
    Israel Hodish; Fiscal Year: 2007
    ..The model presented opens new avenues to the development and testing of potential therapeutic interventions that may ultimately help preserve insulin secretory function in humans with diabetes mellitus. ..