Marc Hochberg

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. ncbi request reprint American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee
    Marc C Hochberg
    Division of Rheumatology, University of Maryland School of Medicine, 10 South Pine Street, MSTF 8 34, Baltimore, MD 21201, USA
    Arthritis Care Res (Hoboken) 64:465-74. 2012
  2. ncbi request reprint What have we learned from the large outcomes trials of COX-2 selective inhibitors? The rheumatologist's perspective
    M C Hochberg
    University of Maryland, Baltimore, Maryland, USA
    Clin Exp Rheumatol 19:S15-22. 2001
  3. ncbi request reprint Alendronate reduces the risk of multiple symptomatic fractures: results from the fracture intervention trial
    Silvina Levis
    Department of Medicine, Osteoporosis Center, University of Miami School of Medicine, 1475 Northwest 12 Avenue, Suite 407, Miami, FL 33101, USA
    J Am Geriatr Soc 50:409-15. 2002
  4. ncbi request reprint Psychological interventions for rheumatoid arthritis: a meta-analysis of randomized controlled trials
    John A Astin
    University of Maryland School of Medicine, Baltimore, USA
    Arthritis Rheum 47:291-302. 2002
  5. ncbi request reprint The risk of cardiovascular thrombotic events with selective cyclooxygenase-2 inhibitors
    Vibeke Strand
    Arthritis Rheum 47:349-55. 2002
  6. pmc Genetic epidemiology of osteoarthritis: recent developments and future directions
    Marc C Hochberg
    Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Curr Opin Rheumatol 25:192-7. 2013
  7. pmc Association of blood lead concentrations with mortality in older women: a prospective cohort study
    Naila Khalil
    University of Pittsburgh, Department of Epidemiology, Pittsburgh, PA, USA
    Environ Health 8:15. 2009
  8. pmc Low bone mineral density is a significant risk factor for low-energy distal radius fractures in middle-aged and elderly men: a case-control study
    Jannike Øyen
    Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway
    BMC Musculoskelet Disord 12:67. 2011
  9. pmc Infections requiring hospitalization in the abatacept clinical development program: an epidemiological assessment
    Teresa A Simon
    Global Health Economics and Outcomes Research, Bristol Myers Squibb, Route 206 and Province Line Roads, Lawrenceville, NJ 08540, USA
    Arthritis Res Ther 12:R67. 2010
  10. ncbi request reprint Bone mineral density and osteoarthritis: data from the Baltimore Longitudinal Study of Aging
    Marc C Hochberg
    Division of Rheumatology, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Osteoarthritis Cartilage 12:S45-8. 2004

Research Grants

  1. STUDY OF OSTEOPOROTIC FRACTURES
    Marc Hochberg; Fiscal Year: 2005
  2. OSTEOPOROTIC FRACTURES
    Marc Hochberg; Fiscal Year: 2001
  3. Role of T Cells in Lung Disease in Systemic Sclerosis
    Marc Hochberg; Fiscal Year: 2006

Detail Information

Publications90

  1. ncbi request reprint American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee
    Marc C Hochberg
    Division of Rheumatology, University of Maryland School of Medicine, 10 South Pine Street, MSTF 8 34, Baltimore, MD 21201, USA
    Arthritis Care Res (Hoboken) 64:465-74. 2012
    ..To update the American College of Rheumatology (ACR) 2000 recommendations for hip and knee osteoarthritis (OA) and develop new recommendations for hand OA...
  2. ncbi request reprint What have we learned from the large outcomes trials of COX-2 selective inhibitors? The rheumatologist's perspective
    M C Hochberg
    University of Maryland, Baltimore, Maryland, USA
    Clin Exp Rheumatol 19:S15-22. 2001
    ..This emphasizes the need for the use of low-dose aspirin in patients at risk for such events, especially myocardial infarction...
  3. ncbi request reprint Alendronate reduces the risk of multiple symptomatic fractures: results from the fracture intervention trial
    Silvina Levis
    Department of Medicine, Osteoporosis Center, University of Miami School of Medicine, 1475 Northwest 12 Avenue, Suite 407, Miami, FL 33101, USA
    J Am Geriatr Soc 50:409-15. 2002
    ....
  4. ncbi request reprint Psychological interventions for rheumatoid arthritis: a meta-analysis of randomized controlled trials
    John A Astin
    University of Maryland School of Medicine, Baltimore, USA
    Arthritis Rheum 47:291-302. 2002
    ..To carry out a systematic review of the literature examining the efficacy of psychological interventions (e.g., relaxation, biofeedback, cognitive-behavioral therapy) in the treatment of rheumatoid arthritis (RA)...
  5. ncbi request reprint The risk of cardiovascular thrombotic events with selective cyclooxygenase-2 inhibitors
    Vibeke Strand
    Arthritis Rheum 47:349-55. 2002
  6. pmc Genetic epidemiology of osteoarthritis: recent developments and future directions
    Marc C Hochberg
    Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Curr Opin Rheumatol 25:192-7. 2013
    ..The goal of this short review is to provide a brief overview of the current status of genetics of osteoarthritis with an emphasis on developments generated in the last year...
  7. pmc Association of blood lead concentrations with mortality in older women: a prospective cohort study
    Naila Khalil
    University of Pittsburgh, Department of Epidemiology, Pittsburgh, PA, USA
    Environ Health 8:15. 2009
    ..We aimed to determine the association between blood lead, all cause and cause specific mortality in elderly, community residing women...
  8. pmc Low bone mineral density is a significant risk factor for low-energy distal radius fractures in middle-aged and elderly men: a case-control study
    Jannike Øyen
    Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway
    BMC Musculoskelet Disord 12:67. 2011
    ..The objectives of this study were to examine BMD and identify factors associated with distal radius fractures in male patients compared with controls recruited from the background population...
  9. pmc Infections requiring hospitalization in the abatacept clinical development program: an epidemiological assessment
    Teresa A Simon
    Global Health Economics and Outcomes Research, Bristol Myers Squibb, Route 206 and Province Line Roads, Lawrenceville, NJ 08540, USA
    Arthritis Res Ther 12:R67. 2010
    ....
  10. ncbi request reprint Bone mineral density and osteoarthritis: data from the Baltimore Longitudinal Study of Aging
    Marc C Hochberg
    Division of Rheumatology, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Osteoarthritis Cartilage 12:S45-8. 2004
    ..Numerous cross-sectional studies have shown that persons with radiographic features of osteoarthritis (OA) of the hips and knees have higher adjusted levels of bone mineral density (BMD)...
  11. ncbi request reprint Recommendations for measurement of bone mineral density and identifying persons to be treated for osteoporosis
    Marc C Hochberg
    Division of Rheumatology, Department of Medicine, University of Maryland School of Medicine, 10 South Pine Street, MSTF 8 34 Baltimore, MD 21201, USA
    Rheum Dis Clin North Am 32:681-9. 2006
    ....
  12. ncbi request reprint Effect of alendronate on the age-specific incidence of symptomatic osteoporotic fractures
    Marc C Hochberg
    University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Bone Miner Res 20:971-6. 2005
    ..Analyses of data from 3658 postmenopausal women with osteoporosis enrolled in the Fracture Intervention Trial showed that alendronate is effective in reducing the risk of symptomatic osteoporotic fractures across a spectrum of ages...
  13. ncbi request reprint The benefit/risk profile of TNF-blocking agents: findings of a consensus panel
    Marc C Hochberg
    Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine, Baltimore 21201, USA
    Semin Arthritis Rheum 34:819-36. 2005
    ..To review the benefits and risks associated with the use of the tumor necrosis factor (TNF)-blockers in various indications (eg, rheumatoid arthritis [RA], Crohn's disease [CD], psoriasis)...
  14. ncbi request reprint COX-2 selective inhibitors in the treatment of arthritis: a rheumatologist perspective
    Marc C Hochberg
    Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine, 10 S Pine St, MSTF 8 34, Baltimore, Maryland 21201, USA
    Curr Top Med Chem 5:443-8. 2005
    ..Cost-effectiveness and cost-utility studies suggest, however, that their use should be limited to patients at high risk of serious upper gastrointestinal side effects, including complicated ulcers...
  15. ncbi request reprint Quality measures in osteoarthritis
    M C Hochberg
    Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Clin Exp Rheumatol 25:102-6. 2007
    ....
  16. ncbi request reprint Nonvertebral fracture risk reduction with nitrogen-containing bisphosphonates
    Marc C Hochberg
    University of Maryland School of Medicine, 10 South Pine Street, MSTF 8 34, Baltimore, MD 21201, USA
    Curr Osteoporos Rep 6:89-94. 2008
    ....
  17. pmc Potential effects of chondroitin sulfate on joint swelling: a GAIT report
    M C Hochberg
    University of Maryland School of Medicine, MSTF 8 34, Baltimore, MD 21201, United States
    Osteoarthritis Cartilage 16:S22-4. 2008
    ..An exploratory post hoc analysis of GAIT patients suggested the effect of chondroitin sulfate on joint swelling occurred more often in patients with milder pain and lower Kellgren-Lawrence Grade at entry...
  18. ncbi request reprint The rate of decline of joint space width in patients with osteoarthritis of the knee: a systematic review and meta-analysis of randomized placebo-controlled trials of chondroitin sulfate
    Marc C Hochberg
    University of Maryland School of Medicine, Baltimore, MD, USA
    Curr Med Res Opin 24:3029-35. 2008
    ..Its role as a potential structure-modifying drug for knee OA, however, remains controversial...
  19. doi request reprint Structure-modifying effects of chondroitin sulfate in knee osteoarthritis: an updated meta-analysis of randomized placebo-controlled trials of 2-year duration
    M C Hochberg
    Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Osteoarthritis Cartilage 18:S28-31. 2010
    ..To update a published meta-analysis of double-blind placebo-controlled randomized clinical trials (RCTs) to assess the efficacy of chondroitin sulfate as a structure-modifying drug for knee osteoarthritis (OA)...
  20. pmc Comparison of the efficacy of the tumour necrosis factor alpha blocking agents adalimumab, etanercept, and infliximab when added to methotrexate in patients with active rheumatoid arthritis
    M C Hochberg
    Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201 USA
    Ann Rheum Dis 62:ii13-6. 2003
    ....
  21. ncbi request reprint Changes in bone density and turnover explain the reductions in incidence of nonvertebral fractures that occur during treatment with antiresorptive agents
    Marc C Hochberg
    University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Clin Endocrinol Metab 87:1586-92. 2002
    ..Antiresorptive agents that do not produce large increases in BMD or large reductions in BCM do not appear to and would not be expected to decrease the risk of nonvertebral fractures...
  22. pmc COX-2: Where are we in 2003? - Be strong and resolute: continue to use COX-2 selective inhibitors at recommended dosages in appropriate patients
    Marc C Hochberg
    Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Arthritis Res Ther 5:28-31. 2003
    ..Co-therapy with low-dose aspirin is recommended in patients with OA and RA at increased risk for cardiovascular events; the need for gastroprotective therapy in such patients is controversial...
  23. ncbi request reprint Preventing fractures in postmenopausal women with osteoporosis. A review of recent controlled trials of antiresorptive agents
    M Hochberg
    Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Maryland School of Medicine, Baltimore, USA
    Drugs Aging 17:317-30. 2000
    ..Data from observational studies suggest, however, that estrogen and etidronic acid may have antifracture efficacy in this population...
  24. ncbi request reprint Session 2: clinical aspects. Clinical assessment of hand OA
    M C Hochberg
    Division of Rheumatology, University of Maryland School of Medicine, and Veterans Administration Maryland Health Care System, Baltimore, 21201, USA
    Osteoarthritis Cartilage 8:S38-40. 2000
    ..The agreements, disagreements and further studies to be performed to answer questions still debated are presented...
  25. ncbi request reprint Treatment of rheumatoid arthritis and osteoarthritis with COX-2-selective inhibitors: a managed care perspective
    Marc C Hochberg
    University of Maryland School of Medicine, Baltimore, USA
    Am J Manag Care 8:S502-17. 2002
    ..Thus, the use of COX-2-selective inhibitors for the management of chronic pain may reduce overall costs and provide an alternative with an improved safety profile compared with traditional NSAIDs...
  26. ncbi request reprint Change in bone turnover and hip, non-spine, and vertebral fracture in alendronate-treated women: the fracture intervention trial
    Douglas C Bauer
    Department of Medicine, Epidemiology and Biostatistics, University of California, San Francisco, California 94105, USA
    J Bone Miner Res 19:1250-8. 2004
    ..In the alendronate group (n = 3105), greater reductions in one or more biochemical marker were associated with a lower risk of fracture...
  27. ncbi request reprint New directions in symptomatic therapy for patients with osteoarthritis and rheumatoid arthritis
    Marc C Hochberg
    Department of Medicine and Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
    Semin Arthritis Rheum 32:4-14. 2002
    ..Therefore, coxibs provide effective relief of pain from osteoarthritis and rheumatoid arthritis, with efficacy that is comparable to traditional NSAIDs, but with a significantly lower incidence of GI complications...
  28. ncbi request reprint Pretreatment levels of bone turnover and the antifracture efficacy of alendronate: the fracture intervention trial
    Douglas C Bauer
    Department of Medicine, Epidemiology and Biostatistics, University of California, San Francisco, California 94107, USA
    J Bone Miner Res 21:292-9. 2006
    ..The nonspine fracture efficacy of alendronate was significantly greater among both osteoporotic and nonosteoporotic women with higher baseline levels of the bone formation marker PINP...
  29. pmc Fractures after antiretroviral initiation
    Michael T Yin
    Department of Medicine, Columbia University Medical Center, New York, NY 10032, USA
    AIDS 26:2175-84. 2012
    ..Bone mineral density declines by 2-6% within 1-2 years after initiation of antiretroviral therapy (ART); however, it is uncertain whether this results in an immediate or cumulative increase in fracture rates...
  30. doi request reprint The utility of changes in serum levels of C-terminal telopeptide of type I collagen in predicting patient response to oral monthly ibandronate therapy
    Marc C Hochberg
    Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Clin Densitom 13:181-9. 2010
    ..61, p=0.0007). These data suggest that 3-mo changes in sCTX levels are associated with 1-yr LS BMD increases in postmenopausal women treated with once-monthly oral ibandronate...
  31. ncbi request reprint The incidence and prevalence of extra-articular and systemic manifestations in a cohort of newly-diagnosed patients with rheumatoid arthritis between 1999 and 2006
    Marc C Hochberg
    Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine, 10 South Pine Street, MSTF 8 34 Baltimore, MD 21201, USA
    Curr Med Res Opin 24:469-80. 2008
    ..To evaluate the incidence and prevalence of extra-articular (ExRA) and systemic (SysM) manifestations in a cohort of newly-diagnosed patients with rheumatoid arthritis (RA) in the United States...
  32. ncbi request reprint Gene expression profiling in peripheral blood mononuclear cells from lupus patients with active and inactive disease
    Violeta Rus
    Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Clin Immunol 112:231-4. 2004
    ..These results highlight the potential use of microarray data in identifying genes associated with disease activity in SLE, which could become potential biomarkers or future therapeutic targets...
  33. ncbi request reprint Long-term experience with alendronate in the treatment of osteoporosis
    Marc C Hochberg
    Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Expert Opin Pharmacother 7:1201-10. 2006
    ..Results from head-to-head studies and meta-analyses suggest that alendronate is more effective than certain other anticatabolic agents in the treatment of patients with osteoporosis...
  34. pmc Meaningful improvement in gait speed in hip fracture recovery
    Dawn E Alley
    Departments of Epidemiology and Public Health, School of Medicine, University of Maryland, Baltimore, Maryland, USA
    J Am Geriatr Soc 59:1650-7. 2011
    ..To estimate meaningful improvements in gait speed observed during recovery from hip fracture and to evaluate the sensitivity and specificity of gait speed changes in detecting change in self-reported mobility...
  35. pmc Positive affect and incidence of frailty in elderly women caregivers and noncaregivers: results of Caregiver-Study of Osteoporotic Fractures
    Eunice Park-Lee
    Department of Epidemiology and Preventive Medicine, School of Medicine, University of Maryland, Baltimore, Maryland, USA
    J Am Geriatr Soc 57:627-33. 2009
    ....
  36. ncbi request reprint Racial differences in the prevalence of vertebral fractures in older men: the Baltimore Men's Osteoporosis Study
    J Kathleen Tracy
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Osteoporos Int 17:99-104. 2006
    ..In conclusion, older white men have a higher prevalence of vertebral fractures than older black men. This may be related to differences in BMD between these groups...
  37. pmc A comparison of prediction models for fractures in older women: is more better?
    Kristine E Ensrud
    Department of Medicine, Minneapolis Veterans Affairs Medical Center, MN 55417, USA
    Arch Intern Med 169:2087-94. 2009
    ..However, it is uncertain whether prediction with FRAX models is superior to that based on parsimonious models...
  38. ncbi request reprint Putting evidence-based medicine into clinical practice: comparing anti-resorptive agents for the treatment of osteoporosis
    Lois E Wehren
    University of Maryland School of Medicine, Baltimore, MD, USA
    Curr Med Res Opin 20:525-31. 2004
    ..To compare the effectiveness of antiresorptive agents in reducing the risk of vertebral and non-vertebral fractures using data from published meta-analyses and the technique of adjusted indirect comparisons...
  39. ncbi request reprint Introduction. New directions in anti-inflammatory therapy and pain management
    Marc C Hochberg
    Division of Rheumatology and Clinical Immunology, University of Maryland Medical Center, Baltimore, MD, USA
    Semin Arthritis Rheum 32:1-3. 2002
  40. pmc Racial differences in bone strength
    Marc C Hochberg
    Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Trans Am Clin Climatol Assoc 118:305-15. 2007
    ..Genetic, nutritional, lifestyle and hormonal factors may contribute to these ethnic/racial differences in bone strength...
  41. ncbi request reprint Racial differences in rate of decline in bone mass in older men: the Baltimore men's osteoporosis study
    J Kathleen Tracy
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Bone Miner Res 20:1228-34. 2005
    ..8 +/- 6.5 (SD) months, we found that older black men have a higher rate of decline in femoral neck and total hip BMD and femoral neck BMAD than older white men...
  42. pmc Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II
    Reva C Lawrence
    NIH, Bethesda, Maryland, USA
    Arthritis Rheum 58:26-35. 2008
    ..A companion article (part I) addresses additional conditions...
  43. ncbi request reprint Randomized trial of effect of alendronate continuation versus discontinuation in women with low BMD: results from the Fracture Intervention Trial long-term extension
    Kristine E Ensrud
    Department of Medicine, VA Medical Center, Minneapolis, Minnesota 55417, USA
    J Bone Miner Res 19:1259-69. 2004
    ..However, among women who discontinued alendronate and took placebo in the extension, BMD remained higher, and reduction in bone turnover was greater than values at FIT baseline, showing persistence of alendronate's effects on bone...
  44. ncbi request reprint Hip fracture in women without osteoporosis
    Stacey A Wainwright
    Bone and Mineral Research Unit, Department of Medicine, Oregon Health and Science University, 3181 S W Sam Jackson Park Road, Mail Code CR113, Portland, Oregon 97239, USA
    J Clin Endocrinol Metab 90:2787-93. 2005
    ..These findings call attention to the many older women who suffer hip fracture but do not have particularly low antecedent BMD measures and help begin to identify risk factors associated with higher bone density levels...
  45. ncbi request reprint Serum hyaluronan levels and radiographic knee and hip osteoarthritis in African Americans and Caucasians in the Johnston County Osteoarthritis Project
    Alan L Elliott
    Division of Rheumatology, School of Medicine, University of North Carolina at Chapel Hill, Thurston Arthritis Research Center, 3330 Thurston Building, CB 7280, Chapel Hill, NC 27599, USA
    Arthritis Rheum 52:105-11. 2005
    ..Serum hyaluronan (HA) has been proposed as a potential biomarker of osteoarthritis (OA). We examined associations between serum HA and radiographic OA in an ethnically diverse, population-based sample...
  46. ncbi request reprint Pins and plaster aren't enough: a call for the evaluation and treatment of patients with osteoporotic fractures
    Ethel S Siris
    Department of Medicine, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    J Clin Endocrinol Metab 88:3482-6. 2003
    ..A call to action is necessary to reduce the human and economic costs associated with this serious and treatable disease...
  47. pmc Delivery and outcomes of a yearlong home exercise program after hip fracture: a randomized controlled trial
    Denise L Orwig
    Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, 21201, USA
    Arch Intern Med 171:323-31. 2011
    ..Our objective was to determine whether a yearlong home-based exercise program initiated following UC could be administered to older patients with hip fracture and improve outcomes...
  48. ncbi request reprint Assessing population risk for postmenopausal osteoporosis: a new strategy using data from the Behavioral Risk Factor Surveillance System (BRFSS)
    Christine R Schneyer
    Division of Endocrinology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Bone Miner Res 23:151-8. 2008
    ..This new method has potential use for guiding implementation of osteoporosis prevention/treatment programs...
  49. doi request reprint Health of community-dwelling adults with mobility limitations in the United States: prevalent health conditions. Part I
    Elizabeth K Rasch
    Rehabilitation Medicine Department, Clinical Research Center, National Institutes of Health, Bethesda, MD, USA
    Arch Phys Med Rehabil 89:210-8. 2008
    ..To characterize the extent and types of prevalent health conditions among nationally representative groups of adults with mobility, nonmobility, and no limitations...
  50. doi request reprint Health of community-dwelling adults with mobility limitations in the United States: incidence of secondary health conditions. Part II
    Elizabeth K Rasch
    Clinical Research Center, Rehabilitation Medicine Department, National Institutes of Health, Bethesda, MD, USA
    Arch Phys Med Rehabil 89:219-30. 2008
    ..To compare incident health conditions that occurred over a 2-year period in nationally representative groups of adults with mobility, nonmobility, and no limitations...
  51. ncbi request reprint Do risk factors for incident hip osteoarthritis (OA) differ from those for progression of hip OA?
    Marc C Hochberg
    Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Rheumatol Suppl 70:6-9. 2004
  52. ncbi request reprint Risk factors for the development and progression of hip osteoarthritis
    Marc C Hochberg
    Division of Rheumatology and Clinical Immunology, University of Maryland School of Medecine, Mediacal Service, Veterans Affairs Maryland Health Care System, Baltimore, MD, USA
    J Rheumatol 32:1135-6. 2005
  53. ncbi request reprint Racial differences in bone mineral density in older men
    Asha George
    Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Bone Miner Res 18:2238-44. 2003
    ..Black men had significantly higher adjusted BMD at all sites. These results may explain, in part, the lower incidence of fractures in older black men...
  54. ncbi request reprint Effectiveness of acupuncture as adjunctive therapy in osteoarthritis of the knee: a randomized, controlled trial
    Brian M Berman
    University of Maryland School of Medicine, Baltimore, Maryland 21207, USA
    Ann Intern Med 141:901-10. 2004
    ..Evidence on the efficacy of acupuncture for reducing the pain and dysfunction of osteoarthritis is equivocal...
  55. ncbi request reprint Effect of Mindfulness-Based Stress Reduction in rheumatoid arthritis patients
    Elizabeth K Pradhan
    The University of Maryland School of Medicine, Baltimore, MD, USA
    Arthritis Rheum 57:1134-42. 2007
    ....
  56. ncbi request reprint Progression of radiographic hip osteoarthritis over eight years in a community sample of elderly white women
    Nancy E Lane
    Division of Rheumatology, Box 0868, University of California at San Francisco, San Francisco, CA 94143, USA
    Arthritis Rheum 50:1477-86. 2004
    ..To describe progression over 8 years in a community-based sample of elderly women with radiographic findings of hip osteoarthritis (RHOA) with or without hip pain...
  57. ncbi request reprint Association of nitrate use with risk of new radiographic features of hip osteoarthritis in elderly white women: the study of osteoporotic fractures
    Nancy E Lane
    Division of Rheumatology, Department of Medicine, Box 0868, University of California at San Francisco, San Francisco, CA 94143, USA
    Arthritis Rheum 49:752-8. 2003
    ..To examine the association between nitrate medication use and the development of new radiographic findings of hip osteoarthritis (OA) in elderly women...
  58. ncbi request reprint Risk factors for a first-incident radiographic vertebral fracture in women > or = 65 years of age: the study of osteoporotic fractures
    Michael C Nevitt
    Department of Epidemiology and Biostatistics, University of California, San Francisco, California 94105, USA
    J Bone Miner Res 20:131-40. 2005
    ..Risk factors and low BMD should be useful to help focus efforts to prevent these fractures...
  59. pmc Relationship of blood lead levels to incident nonspine fractures and falls in older women: the study of osteoporotic fractures
    Naila Khalil
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Bone Miner Res 23:1417-25. 2008
    ..07, 2.45; p trend = 0.014) compared with women with lowest lead level. Blood lead levels are associated with an increased risk of falls and fractures, extending the negative health consequences of lead to include osteoporotic fractures...
  60. ncbi request reprint Cox-2 inhibitors and fracture healing: an argument against such an effect
    Marc C Hochberg
    J Bone Miner Res 18:583; author reply 584-7. 2003
  61. ncbi request reprint The risk of hospitalized infection in patients with rheumatoid arthritis
    Allison L Smitten
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    J Rheumatol 35:387-93. 2008
    ..To determine whether patients with rheumatoid arthritis (RA) are at increased risk of hospitalized infection and whether the risk varies by RA treatment...
  62. ncbi request reprint Performance of risk indices for identifying low bone density in postmenopausal women
    Piet Geusens
    Biomedical Research Institute, Limburg University, Diepenbeek, Belgium
    Mayo Clin Proc 77:629-37. 2002
    ..To examine the ability of 4 published osteoporosis risk indices to identify women with low bone density...
  63. ncbi request reprint COX-2-selective inhibitors in the treatment of arthritis
    Thomas J Schnitzer
    Office of Clinical Research and Training, Northwestern University School of Medicine, Chicago, IL 60611, USA
    Cleve Clin J Med 69:SI20-30. 2002
    ..The use of coxibs to treat OA and RA is recommended as first-line therapy when symptoms of pain and inflammation are present in patients vulnerable to potential NSAID-associated GI toxicity...
  64. ncbi request reprint Meta-analysis of the efficacy of alendronate for the prevention of hip fractures in postmenopausal women
    Socrates E Papapoulos
    Department of Endocrinology and Metabolic Diseases, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Osteoporos Int 16:468-74. 2005
    ..The overall reduction is consistent among different patient populations...
  65. ncbi request reprint Hearing sensitivity and the risk of incident falls and fracture in older women: the study of osteoporotic fractures
    Elizabeth L Purchase-Helzner
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Ann Epidemiol 14:311-8. 2004
    ..We further hypothesized that decreased bone mineral density would be associated with hearing loss...
  66. ncbi request reprint Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: randomised controlled trial
    Thomas J Schnitzer
    Office of Clinical Research and Training, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Lancet 364:665-74. 2004
    ....
  67. ncbi request reprint Classification algorithms for hip fracture prediction based on recursive partitioning methods
    Hua Jin
    Department of Radiology University of California, San Francisco 94143 0946, USA
    Med Decis Making 24:386-98. 2004
    ..A dual X-ray absorptiometry hip scan and information from clinical examinations can identify subjects with elevated 5-year hip fracture risk without loss of efficiency to more costly and complicated algorithms...
  68. ncbi request reprint Treatment with once-weekly alendronate 70 mg compared with once-weekly risedronate 35 mg in women with postmenopausal osteoporosis: a randomized double-blind study
    Clifford J Rosen
    Maine Center of Osteoporosis Research and Education and St Joseph Hospital, Bangor, Maine 04401, USA
    J Bone Miner Res 20:141-51. 2005
    ..These two agents were compared in a 12-month head-to-head trial. Greater gains in BMD and greater reductions in markers of bone turnover were seen with alendronate compared with risedronate with similar tolerability...
  69. ncbi request reprint Bone mineral density and the risk of incident nonspinal fractures in black and white women
    Jane A Cauley
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA
    JAMA 293:2102-8. 2005
    ..Black women have a lower rate of fracture than white women, but whether bone mineral density (BMD) predicts fracture risk as well in black women as it does in white women is not established...
  70. ncbi request reprint Prevalence of knee symptoms and radiographic and symptomatic knee osteoarthritis in African Americans and Caucasians: the Johnston County Osteoarthritis Project
    Joanne M Jordan
    Thurston Arthritis Research Center and Department of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599 7280, USA
    J Rheumatol 34:172-80. 2007
    ..To report contemporary estimates of the prevalence of knee-related osteoarthritis (OA) outcomes in African Americans and Caucasians aged > or = 45 years...
  71. ncbi request reprint Letter to the editor
    Marc C Hochberg
    Bone 35:1222-4; author reply 1225-6. 2004
  72. ncbi request reprint Response to expression of concern regarding VIGOR study
    Claire Bombardier
    N Engl J Med 354:1196-9. 2006
  73. ncbi request reprint Controversies in COX-2 selective inhibition
    Lee S Simon
    Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Rheumatol 29:1501-10. 2002
  74. ncbi request reprint The risk of herpes zoster in patients with rheumatoid arthritis in the United States and the United Kingdom
    Allison L Smitten
    Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Arthritis Rheum 57:1431-8. 2007
    ..To determine whether the incidence of herpes zoster is elevated in patients with rheumatoid arthritis (RA) and whether herpes zoster is associated with use of disease-modifying antirheumatic drugs (DMARDs) in patients with RA...
  75. ncbi request reprint Visual acuity, contrast sensitivity, and mortality in older women: Study of osteoporotic fractures
    Kathryn L Pedula
    Center for Health Research, Kaiser Permanente Northwest, Portland, Oregon 97227, USA
    J Am Geriatr Soc 54:1871-7. 2006
    ..To determine whether poorer visual acuity and contrast sensitivity are independent risk factors for all-cause and traumatic mortality in older women...
  76. ncbi request reprint How useful are measures of BMD and bone turnover?
    Paul D Miller
    Colorado Center for Bone Research, Lakewood, CO, USA
    Curr Med Res Opin 21:545-54. 2005
    ..Analyses that have suggested that change in BMD or bone turnover 'explains' little of change in fracture risk with treatment appear to be flawed. Although neither can perfectly predict fracture, they are our current best alternatives...
  77. doi request reprint Long-term risk of incident vertebral fractures
    Jane A Cauley
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    JAMA 298:2761-7. 2007
    ..Women with low bone mineral density (BMD) and prevalent vertebral fractures have a greater risk of incident vertebral fractures over the short-term, but their absolute risk of vertebral fracture over the long-term is uncertain...
  78. ncbi request reprint Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), cardiovascular outcomes: randomised controlled trial
    Michael E Farkouh
    Cardiovascular Clinical Research Center, New York University School of Medicine, 530 First Avenue, New York, NY 10016, USA
    Lancet 364:675-84. 2004
    ....
  79. ncbi request reprint Pain exacerbation as a major source of lost productive time in US workers with arthritis
    Judith A Ricci
    Caremark, Hunt Valley, MD 21031, USA
    Arthritis Rheum 53:673-81. 2005
    ..To estimate the prevalence of arthritis and arthritis pain exacerbations in US workers including impact on functioning and lost productive work time (LPT)...
  80. ncbi request reprint Prevalence of rheumatoid arthritis in persons 60 years of age and older in the United States: effect of different methods of case classification
    Elizabeth K Rasch
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland 20782, USA
    Arthritis Rheum 48:917-26. 2003
    ..To determine prevalence estimates for rheumatoid arthritis (RA) in noninstitutionalized older adults in the US. Prevalence estimates were compared using 3 different classification methods based on current classification criteria for RA...
  81. ncbi request reprint Quantitative magnetic resonance imaging evaluation of knee osteoarthritis progression over two years and correlation with clinical symptoms and radiologic changes
    Jean Pierre Raynauld
    Centre Hospitalier de l Universite de Montreal, Hopital Notre Dame, and Université de Montréal, Montreal, Quebec, Canada
    Arthritis Rheum 50:476-87. 2004
    ..To evaluate the change in osteoarthritic (OA) knee cartilage volume over a two-year period with the use of magnetic resonance imaging (MRI) and to correlate the MRI changes with radiologic changes...
  82. ncbi request reprint Concomitant therapy: an outcome variable for musculoskeletal disorders? Part 2: total joint replacement in osteoarthritis trials
    Jean Francis Maillefert
    Dijon University Hospital and INSERM ERIT M 0204, University of Burgundy, Dijon, France
    J Rheumatol 32:2449-51. 2005
    ..quot;..
  83. ncbi request reprint Nutritional supplements for knee osteoarthritis--still no resolution
    Marc C Hochberg
    N Engl J Med 354:858-60. 2006
  84. ncbi request reprint Association of the G-174C variant in the interleukin-6 promoter region with bone loss and fracture risk in older women
    Susan P Moffett
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Bone Miner Res 19:1612-8. 2004
    ..Variation at the IL-6 locus may contribute to the genetic susceptibility to bone fragility...
  85. ncbi request reprint Binocular visual-field loss increases the risk of future falls in older white women
    Anne L Coleman
    Jules Stein Eye Institute, Los Angeles, CA 90095, USA
    J Am Geriatr Soc 55:357-64. 2007
    ..To examine the relationship between binocular visual field loss and the risk of incident frequent falls in older white women...
  86. ncbi request reprint Bone mineral density and age-related maculopathy in older women
    Robin L Seitzman
    Department of Ophthalmology, Jules Stein Eye Institute, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095, USA
    J Am Geriatr Soc 55:740-6. 2007
    ..To determine whether bone mineral density (BMD) is associated with age-related maculopathy (ARM) risk in older women...
  87. ncbi request reprint OMERACT/OARSI initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis
    Laure Gossec
    Medicine Faculty, Paris 5 René Descartes University AP HP, Cochin Hospital, Department of Rheumatology B, Paris, France
    J Rheumatol 34:1432-5. 2007
    ..quot;..
  88. pmc A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis
    Allison L Smitten
    Duke University School of Medicine, Duke South, Durham, NC, 27710 USA
    Arthritis Res Ther 10:R45. 2008
    ..The risk of malignancies in patients with rheumatoid arthritis (RA) has raised some concern, particularly with immunosuppressive approaches to disease management...
  89. doi request reprint Glaucoma risk and the consumption of fruits and vegetables among older women in the study of osteoporotic fractures
    Anne L Coleman
    Department of Ophthalmology and Jules Stein Eye Institute, University of California Los Angeles, 100 Stein Plaza, Los Angeles, CA 90095, USA
    Am J Ophthalmol 145:1081-9. 2008
    ..To explore the association between the consumption of fruits and vegetables and the presence of glaucoma...
  90. doi request reprint Drug Insight: choosing a drug treatment strategy for women with osteoporosis-an evidence--based clinical perspective
    Piet P Geusens
    Department of Internal Medicine, Division of Rheumatology, University Hospital, P Debyelaan 25, Box 5800, 6202 AZ Maastricht, The Netherlands
    Nat Clin Pract Rheumatol 4:240-8. 2008
    ..Other determinants include the potential extraskeletal benefits and safety concerns of the drug, patient preferences and reimbursement issues...

Research Grants12

  1. STUDY OF OSTEOPOROTIC FRACTURES
    Marc Hochberg; Fiscal Year: 2005
    ....
  2. OSTEOPOROTIC FRACTURES
    Marc Hochberg; Fiscal Year: 2001
    ..We propose using our archived DNA specimens and existing data about hip and vertebral fractures, breast cancer, bone mass, serum sex hormones and lipoproteins to determine whether these ER variations have biological importance. ..
  3. Role of T Cells in Lung Disease in Systemic Sclerosis
    Marc Hochberg; Fiscal Year: 2006
    ..The new information that is gained will advance knowledge of T-cell dependent mechanisms of pulmonary fibrosis in scleroderma. ..