M P Hlastala

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi The alcohol breath test--a review
    M P Hlastala
    Department of Physiology and Biophysics, University of Washington, Seattle 98195 6522, USA
    J Appl Physiol 84:401-8. 1998
  2. ncbi Gravity is an important but secondary determinant of regional pulmonary blood flow in upright primates
    R W Glenny
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    J Appl Physiol 86:623-32. 1999
  3. ncbi Ventilation heterogeneity is increased in hypocapnic dogs but not pigs
    K B Domino
    Department of Anesthesiology, University of Washington, Seattle 98195 6540, USA
    Respir Physiol 111:89-100. 1998
  4. ncbi Spatial distribution of venous gas emboli in the lungs
    J E Souders
    Department of Medicine, University of Washington, Seattle 98195 6522, USA
    J Appl Physiol 87:1937-47. 1999
  5. ncbi Minimal redistribution of pulmonary blood flow with exercise in racehorses
    S L Bernard
    Department of Physiology and Biophysics, University of Washington, Seattle 98195 6522, USA
    J Appl Physiol 81:1062-70. 1996
  6. ncbi Isocapnic hyperventilation increases carbon monoxide elimination and oxygen delivery
    T C Kreck
    Department of Medicine, University of Washington, Seattle, Washington 98195 6522, USA
    Am J Respir Crit Care Med 163:458-62. 2001
  7. ncbi Vasomotor tone does not affect perfusion heterogeneity and gas exchange in normal primate lungs during normoxia
    R W Glenny
    Department of Medicine, University of Washington 98195, USA
    J Appl Physiol 89:2263-7. 2000
  8. ncbi Selected contribution: redistribution of pulmonary perfusion during weightlessness and increased gravity
    R W Glenny
    Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98195, USA
    J Appl Physiol 89:1239-48. 2000
  9. ncbi Exercise alters fractal dimension and spatial correlation of pulmonary blood flow in the horse
    S E Sinclair
    Department of Medicine, University of Washington, Seattle 98195 6522, USA
    J Appl Physiol 88:2269-78. 2000
  10. ncbi Determination of regional ventilation and perfusion in the lung using xenon and computed tomography
    T C Kreck
    Department of Medicine, University of Washington, Seattle, WA 98195-6522, USA
    J Appl Physiol 91:1741-9. 2001

Detail Information

Publications13

  1. ncbi The alcohol breath test--a review
    M P Hlastala
    Department of Physiology and Biophysics, University of Washington, Seattle 98195 6522, USA
    J Appl Physiol 84:401-8. 1998
    ..The dynamics of airway alcohol exchange results in a positively sloped exhaled alveolar plateau that contributes to considerable breathing pattern-dependent variation in measured breath alcohol concentration measurements...
  2. ncbi Gravity is an important but secondary determinant of regional pulmonary blood flow in upright primates
    R W Glenny
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    J Appl Physiol 86:623-32. 1999
    ..Although important, gravity is not the predominant determinant of pulmonary perfusion heterogeneity in upright primates. Because of anatomic similarities, the same may be true for humans...
  3. ncbi Ventilation heterogeneity is increased in hypocapnic dogs but not pigs
    K B Domino
    Department of Anesthesiology, University of Washington, Seattle 98195 6540, USA
    Respir Physiol 111:89-100. 1998
    ..05) in pigs. We conclude that hypocapnia increases ventilation heterogeneity in dogs but not in pigs, most likely related to an interspecies difference in collateral ventilation...
  4. ncbi Spatial distribution of venous gas emboli in the lungs
    J E Souders
    Department of Medicine, University of Washington, Seattle 98195 6522, USA
    J Appl Physiol 87:1937-47. 1999
    ..0 increase in relative baseline flow (P = 0.008). We conclude that the distribution of gaseous emboli is influenced by buoyancy and flow dynamics within the pulmonary vasculature...
  5. ncbi Minimal redistribution of pulmonary blood flow with exercise in racehorses
    S L Bernard
    Department of Physiology and Biophysics, University of Washington, Seattle 98195 6522, USA
    J Appl Physiol 81:1062-70. 1996
    ..The majority of flow redistribution was due to flow increasing to the dorsal region of the lung during exercise at 90% of maximal oxygen consumption (a flow gradient of 0.20 ml. min-1.cm-1 up the lung; P = 0.04)...
  6. ncbi Isocapnic hyperventilation increases carbon monoxide elimination and oxygen delivery
    T C Kreck
    Department of Medicine, University of Washington, Seattle, Washington 98195 6522, USA
    Am J Respir Crit Care Med 163:458-62. 2001
    ..RR, and 4. VT ventilatory patterns. Isocapnic hyperventilation, in our animal model, did not alter arterial or pulmonary blood pressures, arterial pH, or cardiac output. Isocapnic hyperventilation is a promising therapy for CO poisoning...
  7. ncbi Vasomotor tone does not affect perfusion heterogeneity and gas exchange in normal primate lungs during normoxia
    R W Glenny
    Department of Medicine, University of Washington 98195, USA
    J Appl Physiol 89:2263-7. 2000
    ..Despite the heterogeneous distribution of blood flow, active regulation of regional perfusion is not required for efficient gas exchange...
  8. ncbi Selected contribution: redistribution of pulmonary perfusion during weightlessness and increased gravity
    R W Glenny
    Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98195, USA
    J Appl Physiol 89:1239-48. 2000
    ..We conclude that both gravity and the geometry of the pulmonary vascular tree influence regional pulmonary blood flow. However, the structure of the vascular tree is the primary determinant of regional perfusion in these animals...
  9. ncbi Exercise alters fractal dimension and spatial correlation of pulmonary blood flow in the horse
    S E Sinclair
    Department of Medicine, University of Washington, Seattle 98195 6522, USA
    J Appl Physiol 88:2269-78. 2000
    ..This is the first study to document a change in fractal dimension as a result of increasing pulmonary blood flow. Spatial differences in response to vasoregulatory mediators may play a role in this phenomenon...
  10. ncbi Determination of regional ventilation and perfusion in the lung using xenon and computed tomography
    T C Kreck
    Department of Medicine, University of Washington, Seattle, WA 98195-6522, USA
    J Appl Physiol 91:1741-9. 2001
    ..Sequential images acquired by CT during Xe breathing can be used to determine both regional V and Q noninvasively with high spatial resolution...
  11. ncbi Characterization of bronchial-to-pulmonary communications
    S Bernard
    Department of Medicine, University of Washington, VA Medical Center, Seattle, WA, USA
    Arch Physiol Biochem 111:317-8. 2003
  12. ncbi Highly soluble gases exchange in the pulmonary airways
    M P Hlastala
    University of Washington, Seattle, WA 98195, USA
    Arch Physiol Biochem 111:289-92. 2003
  13. ncbi Regional hypoxic pulmonary vasoconstriction in prone pigs
    I R Starr
    Department of Medicine, Univ. of Washington, Seattle, WA, USA
    J Appl Physiol 99:363-70. 2005
    ..We determined that pulmonary blood flow changes, caused by HPV, produced distinct response patterns that were seen in similar regions across our prone porcine model...