Jan Hirsch

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Proteomics: current techniques and potential applications to lung disease
    Jan Hirsch
    Cardiovascular Research Institute, University of California, San Francisco, 505 Parnassus Ave HSW 825, San Francisco, CA 94143 0130, USA
    Am J Physiol Lung Cell Mol Physiol 287:L1-23. 2004
  2. pmc Impact of low and high tidal volumes on the rat alveolar epithelial type II cell proteome
    Jan Hirsch
    Cardiovascular Research Institute, University of California, San Francisco, CA 94143 0130, USA
    Am J Respir Crit Care Med 175:1006-13. 2007
  3. pmc Alterations in the proteome of pulmonary alveolar type II cells in the rat after hepatic ischemia-reperfusion
    Jan Hirsch
    Anesthesia and Perioperative Care, Mass Spectrometry Facility, University of California, San Francisco, CA, USA
    Crit Care Med 36:1846-54. 2008
  4. ncbi request reprint Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells
    Xiaohui Fang
    Cardiovascular Research Inst, Department of Medicine Physiology, Univ of California, San Francisco, CA 94143 0130, USA
    Am J Physiol Lung Cell Mol Physiol 290:L242-9. 2006
  5. ncbi request reprint Warm ischemia-induced alterations in oxidative and inflammatory proteins in hepatic Kupffer cells in rats
    Jan Hirsch
    Mass Spectrometry Facility, Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143 0446, USA
    Mol Cell Proteomics 5:979-86. 2006
  6. ncbi request reprint Fluid transport across cultured rat alveolar epithelial cells: a novel in vitro system
    Xiaohui Fang
    Cardiovascular Research Institute, University of California, San Francisco, 94143 0130, USA
    Am J Physiol Lung Cell Mol Physiol 287:L104-10. 2004
  7. ncbi request reprint Mass spectrometric analysis of protein mixtures at low levels using cleavable 13C-isotope-coded affinity tag and multidimensional chromatography
    Kirk C Hansen
    Department of Pharmaceutical Chemistry, Mass Spectrometry Facility, University of California San Francisco, San Francisco, California 94143 0446, USA
    Mol Cell Proteomics 2:299-314. 2003

Detail Information

Publications7

  1. ncbi request reprint Proteomics: current techniques and potential applications to lung disease
    Jan Hirsch
    Cardiovascular Research Institute, University of California, San Francisco, 505 Parnassus Ave HSW 825, San Francisco, CA 94143 0130, USA
    Am J Physiol Lung Cell Mol Physiol 287:L1-23. 2004
    ..This article provides a brief review of the most promising proteomics methods and some of their applications to pulmonary research...
  2. pmc Impact of low and high tidal volumes on the rat alveolar epithelial type II cell proteome
    Jan Hirsch
    Cardiovascular Research Institute, University of California, San Francisco, CA 94143 0130, USA
    Am J Respir Crit Care Med 175:1006-13. 2007
    ..Mechanical ventilation with high tidal volumes leads to increased permeability, generation of inflammatory mediators, and damage to alveolar epithelial cells (ATII)...
  3. pmc Alterations in the proteome of pulmonary alveolar type II cells in the rat after hepatic ischemia-reperfusion
    Jan Hirsch
    Anesthesia and Perioperative Care, Mass Spectrometry Facility, University of California, San Francisco, CA, USA
    Crit Care Med 36:1846-54. 2008
    ..Hepatic ischemia-reperfusion can be associated with acute lung injury. Alveolar epithelial type II cells (ATII) play an important role in maintaining lung homeostasis in acute lung injury...
  4. ncbi request reprint Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells
    Xiaohui Fang
    Cardiovascular Research Inst, Department of Medicine Physiology, Univ of California, San Francisco, CA 94143 0130, USA
    Am J Physiol Lung Cell Mol Physiol 290:L242-9. 2006
    ..We conclude that CFTR is expressed in cultured human AT II cells and may contribute to cAMP-regulated apical-basolateral fluid transport...
  5. ncbi request reprint Warm ischemia-induced alterations in oxidative and inflammatory proteins in hepatic Kupffer cells in rats
    Jan Hirsch
    Mass Spectrometry Facility, Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143 0446, USA
    Mol Cell Proteomics 5:979-86. 2006
    ..The ability to simultaneously monitor several pathways involved in reperfusion stress may result in important mechanistic insight and possibly new treatment options...
  6. ncbi request reprint Fluid transport across cultured rat alveolar epithelial cells: a novel in vitro system
    Xiaohui Fang
    Cardiovascular Research Institute, University of California, San Francisco, 94143 0130, USA
    Am J Physiol Lung Cell Mol Physiol 287:L104-10. 2004
    ..In conclusion, this novel in vitro system can be used to measure net vectorial fluid transport across cultured, polarized alveolar epithelial cells...
  7. ncbi request reprint Mass spectrometric analysis of protein mixtures at low levels using cleavable 13C-isotope-coded affinity tag and multidimensional chromatography
    Kirk C Hansen
    Department of Pharmaceutical Chemistry, Mass Spectrometry Facility, University of California San Francisco, San Francisco, California 94143 0446, USA
    Mol Cell Proteomics 2:299-314. 2003
    ..In the latter case, the ICAT method produced significant new information on changes that occur in protein expression levels in a patient suffering from cystic fibrosis...