Research Topics
| Irl B HirschSummaryAffiliation: University of Washington Country: USA Publications
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Detail Information
Publications
Self-Monitoring of Blood Glucose (SMBG) in insulin- and non-insulin-using adults with diabetes: consensus recommendations for improving SMBG accuracy, utilization, and researchIrl B Hirsch
Department of Medicine, University of Washington Medical Center Roosevelt, Seattle, Washington 98105, USA
Diabetes Technol Ther 10:419-39. 2008..The panel also made suggestions for designing future studies that increase the ability to discern optimal models of SMBG utilization for individuals with diabetes who may, or may not, use insulin...- Qualitative evaluation of a mobile phone and web-based collaborative care intervention for patients with type 2 diabetesCourtney Rees Lyles
Department of Health Services, University of Washington, Seattle, Washington 98104, USA
Diabetes Technol Ther 13:563-9. 2011..Drawing on previous web-based diabetes management programs based on the Chronic Care Model, we expanded an intervention to include care management through mobile phones and a game console web browser... 
Web-based collaborative care for type 1 diabetes: a pilot randomized trialKelly P McCarrier
Department of Health Services, University of Washington, Seattle, Washington 98195, USA
Diabetes Technol Ther 11:211-7. 2009....- Sensor-augmented insulin pump therapy: results of the first randomized treat-to-target studyIrl B Hirsch
University of Washington Medical Center Roosevelt, Seattle, Washington 98105, USA
Diabetes Technol Ther 10:377-83. 2008.... - Web-based collaborative care for type 2 diabetes: a pilot randomized trialJames D Ralston
Center for Health Studies, Group Health Cooperative, Seattle, Washington, USA
Diabetes Care 32:234-9. 2009..To test Web-based care management of glycemic control using a shared electronic medical record with patients who have type 2 diabetes... - Practical pearls in insulin pump therapyIrl B Hirsch
University of Washington School of Medicine, Medical Center, 4225 Roosevelt Way NE, Seattle, WA 98101, USA
Diabetes Technol Ther 12:S23-7. 2010..Finally, the introduction of bolus calculators and software to download the pumps has provided technology that when used appropriately can further benefit glycemic control... 
Intensifying insulin therapy in patients with type 2 diabetes mellitusIrl B Hirsch
Diabetes Care Center, Division of Endocrinology, University of Washington School of Medicine, Seattle, Washington 98195, USA
Am J Med 118:21S-6S. 2005....- Continuous subcutaneous insulin infusion (CSII) of insulin aspart versus multiple daily injection of insulin aspart/insulin glargine in type 1 diabetic patients previously treated with CSIIIrl B Hirsch
University of Washington, Seattle, WA, USA
Diabetes Care 28:533-8. 2005..Multiple daily injection (MDI) therapy of bolus insulin aspart and basal insulin glargine was compared with continuous subcutaneous insulin infusion (CSII) with aspart in type 1 diabetic patients previously treated with CSII... - How to best manage glycemia and non-glycemia during the time of acute myocardial infarctionIrl B Hirsch
Division of Metabolism, University of Washington School of Medicine, Seattle, Washington, USA
Diabetes Technol Ther 14:S22-32. 2012..The use of continuous glucose monitoring in this population may allow better ability to safely reach glycemic targets, which it is hoped will improve glycemic control... - Motherhood, apple pie, hemoglobin A(1C), and the DCCTDace L Trence
University of Washington Medical Center, Seattle, Washington 98105, USA
Endocr Pract 18:78-84. 2012..To review recent literature on the limitations of hemoglobin A(1c) (HbA(1c)) as a marker of glycemic control... - Inpatient diabetes: review of data from the cardiac care unitIrl B Hirsch
Department of Medicine, Division of Metabolism, Endocrinology and Nutrition, University of Washington School of Medicine, Seattle, Washington, USA
Endocr Pract 12:27-34. 2006..While we improve our understanding of the basic roles of glucose and insulin in modulating inflammation, we must aggressively treat hyperglycemia to the national goals for this population, which would substantially improve outcomes... - Designing mobile support for glycemic control in patients with diabetesLynne T Harris
Department of Health Services, University of Washington, Magnuson Health Sciences Center, Room H 664, Seattle, WA 98195 7660, USA
J Biomed Inform 43:S37-40. 2010..Participants saw value in the mobile system as an adjunct to the Web-based program and traditional office-based care. Mobile diabetes management systems may represent one strategy to improve the quality of diabetes care... - Impact of prandial plus basal vs basal insulin on glycemic variability in type 2 diabetic patientsIrl B Hirsch
University of Washington Medical Center Roosevelt, 4225 Roosevelt Way NE, Ste 101 Box 354691, Seattle, WA 98105, USA
Endocr Pract 15:343-8. 2009.... - Implementing an intravenous insulin protocol in your practice: practical advice to overcome clinical, administrative, and financial barriersJanet L Kelly
University of Washington Medical Center, School of Pharmacy, Division of Metabolism, Endocrinology, and Nutrition, University of Washington, Seattle, WA, USA
Semin Thorac Cardiovasc Surg 18:346-58. 2006.... - Animal insulin therapy induces a biased insulin antibody response that persists for years after introduction of human insulinShilpa Oak
Department of Medicine, University of Washington, Seattle, WA, USA
Acta Diabetol 47:131-5. 2010..0001). We conclude that IA binding level and epitope specificity are biased by treatment with animal insulin. This bias remains for over 20 years after animal insulin treatment is terminated... - Use of serum and plasma glucose measurements as a benchmark for improved hospital-wide glycemic controlAndrew N Hoofnagle
Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA
Endocr Pract 14:556-63. 2008..To demonstrate the benefit of an institutionally implemented glucose control intervention based on serum and plasma glucose values in the acute inpatient setting... - Insulin analoguesIrl B Hirsch
Department of Medicine, University of Washington School of Medicine, Seattle, WA 98195-6176, USA
N Engl J Med 352:174-83. 2005 - Patient factors associated with glucagonlike peptide 1 receptor agonist use with and without insulinIrl B Hirsch
University of Washington School of Medicine, Seattle, Washington, USA
Endocr Pract 17:707-16. 2011..To evaluate both the patient factors associated with the initiation of exenatide and the real-world treatment patterns of exenatide use with and without insulin... - Clinical review: Realistic expectations and practical use of continuous glucose monitoring for the endocrinologistIrl B Hirsch
University of Washington School of Medicine, Seattle, Washington 98105, USA
J Clin Endocrinol Metab 94:2232-8. 2009..Real-time continuous glucose monitoring (CGM) has been available for type 1 diabetes for several years. This paper is a status report on our early experiences with this next technology... - Inpatient management of adults and children with type 1 diabetesDavid M Tridgell
Division of Metabolism, Endocrinology and Nutrition, University of Washington, 1959 NE Pacific Street, Box 356426, Seattle, WA 98195, USA
Endocrinol Metab Clin North Am 39:595-608. 2010..This article focuses on inpatient and perioperative insulin management of stable, nonketotic, nonpregnant adults and children with type 1 diabetes. These principles can also be applied to patients with steroid-induced hyperglycemia... - Clinical application of emerging sensor technologies in diabetes management: consensus guidelines for continuous glucose monitoring (CGM)Irl B Hirsch
Department of Medicine, University of Washington Medical Center Roosevelt, Seattle, Washington 98105, USA
Diabetes Technol Ther 10:232-44; quiz 245-6. 2008..Finally, researchers, manufacturers, payers, and advocacy groups must join forces on the policy level to create an environment conducive to managing continuous data, measuring outcomes, and formalizing best practices... - Glycemic variability: it's not just about A1C anymore!Irl B Hirsch
University of Washington Medical Center, Seattle, Washington 98105, USA
Diabetes Technol Ther 7:780-3. 2005 - Optimal initiation of insulin in type 2 diabetesIrl B Hirsch
University of Washington, University of Washington Medical Center, Seattle, Washington, USA
MedGenMed 7:49. 2005..In addition to A1C, a patient's age, lifestyle, competence, personal preferences, and comorbidities can be used to help determine the choice of insulin therapy... - Isn't this just bedtime snacking? The potential adverse effects of night-eating symptoms on treatment adherence and outcomes in patients with diabetesShereen A Morse
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA 98195 6560, USA
Diabetes Care 29:1800-4. 2006..Psychosocial variables and emotional triggers may be associated with these behaviors. In patients with diabetes, such behaviors may lead to glucose dysregulation and contribute to obesity and complications... - Arguments against the use of inhaled insulinIrl B Hirsch
University of Washington School of Medicine, Seattle, Washington 98105, USA
Diabetes Technol Ther 9:S111-4. 2007 - Piecing the puzzle together: ACCORDing to whom?Irl B Hirsch
University of Washington School of Medicine Roosevelt, 4225 Roosevelt Avenue Northeast, Suite 101, Seattle, Washington 98105, USA
J Clin Endocrinol Metab 93:1161-3. 2008 - Sepsis and glycemia: read the fine print!Irl B Hirsch
Division of Metabolism, Endocrinology and Nutrition, University of Washington School of Medicine, Seattle, Washington 98195-4691, USA
Endocr Pract 14:389-90. 2008 - Assessment of therapy with continuous subcutaneous insulin infusion in an academic diabetes clinicJusten W Rudolph
Department of Medicine, Division of Metabolism, Endocrinology, and Nutrition, University of Washington School of Medicine, Seattle, Washington, USA
Endocr Pract 8:401-5. 2002..CSII therapy, when provided in conjunction with a standard educational program, should continue to be an important treatment option in appropriately selected patients with type 1 diabetes... - Using an Internet comanagement module to improve the quality of chronic disease careHarold I Goldberg
University of Washington, Seattle, USA
Jt Comm J Qual Saf 29:443-51. 2003..At the University of Washington, a diabetes care module was developed, and the feasibility of allowing patients with type 2 diabetes to comanage their disease from home was pilot tested... - Blood glucose monitoring technology: translating data into practiceIrl B Hirsch
The University of Washington Medical Center, Seattle, Washington, USA
Endocr Pract 10:67-76. 2004..CONCLUSION: Data downloaded from glucose meters can be used in conjunction with written records in logbooks to evaluate glucose patterns and formulate more precise and efficacious therapeutic regimens... - Effect of insulin therapy on nonglycemic variables during acute illnessIrl B Hirsch
University of Washington School of Medicine, Seattle, Washington, USA
Endocr Pract 10:63-70. 2004.... - Practical aspects of real-time continuous glucose monitoringLisa K Gilliam
University of Washington Medical Center, Seattle, Washington 98195 7710, USA
Diabetes Technol Ther 11:S75-82. 2009..In this review, we will discuss the practical benefits and challenges of rt-CGM use, in order to better educate care providers as to which of their patients might actually benefit from this technology... - The contribution of malglycemia to mortality among allogeneic hematopoietic cell transplant recipientsMarilyn J Hammer
Department of Biobehavioral Nursing and Health Systems, University of Washington, Seattle, Washington, USA
Biol Blood Marrow Transplant 15:344-51. 2009..The applicability of these findings to other situations and whether correcting malglycemia in HCT can lead to reductions in mortality remain to be determined... - Treatment of patients with severe insulin deficiency; what we have learned over the past 2 yearsIrl B Hirsch
Diabetes Care Center and the Department of Medicine, University of Washington School of Medicine, 1959 NE Pacific, UW Mailbox 356176, Seattle, WA 98195-6176, USA
Am J Med 116:17S-22S. 2004..Newer insulin analogues, improved devices for home glucose monitoring, and pulmonary inhaled insulin are other innovations that promise improvement of hemoglobin A(1c) levels... - The relationship of depressive symptoms to symptom reporting, self-care and glucose control in diabetesPaul S Ciechanowski
Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98195, USA
Gen Hosp Psychiatry 25:246-52. 2003..Because of their association with clinical aspects of diabetes care such as diabetes symptom reporting and adherence to diabetes self-care, depressive symptoms are important to recognize in treating patients with diabetes... - The rationale and management of hyperglycemia for in-patients with cardiovascular disease: time for changeDace L Trence
Division of Metabolism, Endocrinology, and Nutrition, University of Washington School of Medicine, Seattle, Washington 98195-6176, USA
J Clin Endocrinol Metab 88:2430-7. 2003..v. and s.c. insulin. Although there are several appropriate options for both of these routes of administration, it is critical that all caregivers involved in this population's care are knowledgeable about insulin strategies... - Outpatient insulin therapy in type 1 and type 2 diabetes mellitus: scientific reviewDawn E DeWitt
Division of General Internal Medicine, Department of Medicine, University of Washington, Seattle, USA
JAMA 289:2254-64. 2003..The key to effective insulin therapy is an understanding of principles that, when implemented, can result in improved diabetes control...