Research Topics
| A T HirschSummaryAffiliation: University of Minnesota Country: USA Publications
| Collaborators
|
Detail Information
Publications
Gaps in public knowledge of peripheral arterial disease: the first national PAD public awareness surveyAlan T Hirsch
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Ste 300, 1300 S 2nd St, Minneapolis, MN 55454, USA
Circulation 116:2086-94. 2007..Nevertheless, public knowledge of PAD as a morbid and mortal disease has not been previously assessed...
Special communication: mandate for creation of a national peripheral arterial disease public awareness program: an opportunity to improve cardiovascular healthAlan T Hirsch
Division of Epidemiology, University of Minnesota School of Public Health, and Vascular Medicine Program, Minneapolis Heart Institute, Rochester, MN, USA
Angiology 55:233-42. 2004....
The potential role of angiotensin-converting enzyme inhibition in peripheral arterial diseaseAlan T Hirsch
Vascular Medicine Program, Minneapolis Heart Institute, and Division of Epidemiology, University of Minnesota School of Public Health, Minneapolis, MN 55454, USA
Vasc Med 8:273-8. 2003..These studies suggest that ACE inhibitor therapy should be considered in the routine management of individuals with PAD, regardless of whether they have hypertension or left ventricular dysfunction...
Mandate for creation of a national peripheral arterial disease public awareness program: an opportunity to improve cardiovascular healthAlan T Hirsch
Division of Epidemiology, University of Minnesota School of Public Health, and Vascular Medicine Program, Minneapolis Heart Institute, Rochester, MN, USA
Vasc Endovascular Surg 38:121-30. 2004....
Mandate for creation of a national peripheral arterial disease public awareness program: an opportunity to improve cardiovascular healthAlan T Hirsch
Division of Epidemiology, University of Minnesota School of Public Health, Minneapolis, Minnesota, USA
J Vasc Surg 39:474-81. 2004..provides an overview of the National Heart, Lung, and Blood Institute PAD education meeting; and (5). outlines the "next steps" required to accomplish these goals...
Vascular disease, hypertension, and prevention: "from endothelium to clinical events"Alan T Hirsch
Vascular Medicine Program, Cardiovascular Division, Minnesota Vascular Diseases Center, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
J Am Coll Cardiol 42:377-9. 2003
National health care costs of peripheral arterial disease in the Medicare populationAlan T Hirsch
Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, MN 55454 1015, USA
Vasc Med 13:209-15. 2008..The potential impact of earlier PAD detection and use of outpatient preventive strategies on total national PAD health care costs is unknown...
Undertreatment of dyslipidemia in peripheral arterial disease and other high-risk populations: an opportunity for cardiovascular disease reductionAlan T Hirsch
Vascular Medicine Programs, Cardiovascular Division, Minnesota Vascular Diseases Center, University of Minnesota Medical School, Minneapolis, MN 55455, USA
Vasc Med 7:323-31. 2002..The use of statin medications in high-risk groups such as PAD patients could prove particularly beneficial in reducing cardiovascular morbidity and mortality and therefore merits prospective clinical investigation...
Images in clinical medicine. Infrarenal aortic occlusionAlan T Hirsch
Abbott Northwestern Hospital, Minneapolis, MN 55407, USA
N Engl J Med 359:735. 2008
Peripheral arterial disease detection, awareness, and treatment in primary careA T Hirsch
Vascular Medicine Program, Minnesota Vascular Diseases Center, Mayo Mail Code 508, University of Minnesota Medical School, 420 Delaware St, SE, Minneapolis, MN 55455, USA
JAMA 286:1317-24. 2001..Peripheral arterial disease (PAD) is a manifestation of systemic atherosclerosis that is common and is associated with an increased risk of death and ischemic events, yet may be underdiagnosed in primary care practice...
The Minnesota Regional Peripheral Arterial Disease Screening Program: toward a definition of community standards of careA T Hirsch
Vascular Medicine Program, Minnesota Vascular Diseases Center, University of Minnesota Medical School, Minneapolis 55455, USA
Vasc Med 6:87-96. 2001..These data can assist in the future development of PAD awareness, education, and treatment programs...
Albuminuria and peripheral arterial disease: results from the multi-ethnic study of atherosclerosis (MESA)K Wattanakit
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 55454 1015, United States
Atherosclerosis 201:212-6. 2008..The association of albuminuria with cardiovascular disease (CVD) is increasingly recognized, but its association with peripheral arterial disease (PAD) is not well characterized in subjects with or without diabetes...
Risk factors for peripheral arterial disease incidence in persons with diabetes: the Atherosclerosis Risk in Communities (ARIC) StudyKeattiyoat Wattanakit
Division of Epidemiology, School of Public Health, University of Minnesota, Suite 300, 1300 South 2nd Street, Minneapolis, MN 55454-1015, USA
Atherosclerosis 180:389-97. 2005..CONCLUSION: These markers might be useful to identify individuals with diabetes at particular risk for PAD...
Proteinuria in a placebo-controlled study of basic fibroblast growth factor for intermittent claudicationL T Cooper
Mayo Clinic and Foundation, Cardiovascular Division, Rochester, MN 55905, USA
Vasc Med 6:235-9. 2001..Future clinical trials of bFGF protein should carefully monitor renal function and consider alternative dosing schedules and drug administration routes...
A patient-derived perspective of health-related quality of life with peripheral arterial diseaseDiane Treat-Jacobson
University of Minnesota, USA
J Nurs Scholarsh 34:55-60. 2002..To evaluate the effects of peripheral artery disease (PAD) on health-related quality of life (HRQoL) from the patient's perspective to establish a foundation for systematic PAD-specific HRQoL assessment in this population...
Design of the multicenter standardized supervised exercise training intervention for the claudication: exercise vs endoluminal revascularization (CLEVER) studyUlf G Bronas
School of Nursing, University of Minnesota, Minneapolis, MN 55455, USA
Vasc Med 14:313-21. 2009....
Process of care and outcomes in patients with peripheral arterial diseaseTracie C Collins
Houston Center for Quality of Care and Utilization Studies, and Section of Health Services Research, Baylor College of Medicine, Houston, Texas, USA
J Gen Intern Med 22:942-8. 2007..We investigated the association of process of care measures with adverse limb and systemic events in patients with peripheral arterial disease (PAD)...
Correlates and consequences of venous thromboembolism: The Iowa Women's Health StudyPamela L Lutsey
University of Minnesota, Minneapolis, USA
Am J Public Health 100:1506-13. 2010..We sought to document incidence, case-fatality, and recurrence rates of venous thromboembolism (VTE) in women and to explore the relationship of demographic, lifestyle, and anthropometric factors to VTE incidence...
Developing pharmaceutical treatments for peripheral artery diseaseDaniel A Duprez
Cardiovascular Division, Mayo Mail Code 508, University of Minnesota, 420 Delaware St SE, Minneapolis, MN 55455, USA
Expert Opin Investig Drugs 12:101-8. 2003....
International heterogeneity in diagnostic frequency and clinical outcomes of ascending aortic intramural hematomaJamie M Pelzel
Cardiovascular Division, University of Minnesota Medical School, Minneapolis, Minnesota, USA
J Am Soc Echocardiogr 20:1260-8. 2007..Differing diagnostic frequencies and management strategies for intramural hematoma (IMH) have been described in North American (NA)/European and Japanese/Korean studies...
The efficacy and safety of enhanced external counterpulsation in patients with peripheral arterial diseaseBhavik V Thakkar
Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Minneapolis, MN 55407, USA
Vasc Med 15:15-20. 2010....
Ankle-brachial index and hemostatic markers in the Atherosclerosis Risk in Communities (ARIC) study cohortLaura M Reich
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA
Vasc Med 12:267-73. 2007..56-4.65), for beta-TG was 1.80 (95% CI 1.12-2.88), and for CRP was 1.57 (95% CI 0.84-2.95). Plasma levels of hemostatic and inflammatory markers are elevated in PAD, suggesting these processes are involved in the pathophysiology of PAD...
Kidney function and risk of peripheral arterial disease: results from the Atherosclerosis Risk in Communities (ARIC) StudyKeattiyoat Wattanakit
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Suite 300, 1300 South Second Street, Minneapolis, MN 55454 1015, USA
J Am Soc Nephrol 18:629-36. 2007..56 (95% CI 1.13 to 2.14). Patients with CKD are at increased risk for incident PAD. Development of strategies for screening and prevention of PAD in this high-risk population seems warranted...
Association of anger proneness, depression and low social support with peripheral arterial disease: the Atherosclerosis Risk in Communities StudyKeattiyoat Wattanakit
Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, MN 55454-1015, USA
Vasc Med 10:199-206. 2005..These findings may warrant confirmation in further studies and, if causal, could serve as a unique target for a PAD prevention trial...
Effect of bilateral nephrectomy on active renin, angiotensinogen, and renin glycoforms in plasma and myocardiumS A Katz
Division of Nephrology, Hennepin County Medical Center, Minneapolis, Minn 55415 1829, USA
Hypertension 30:259-66. 1997..Control myocardial angiotensinogen concentrations are too low to result from simple diffusion equilibrium between plasma and the myocardial interstitium...
PAD awareness, risk, and treatment: new resources for survival--the USA PARTNERS programA T Hirsch
Vascular Medicine Program, Minnesota Vascular Diseases Center, University of Minnesota Medical School, Minneapolis 55455, USA
Vasc Med 6:9-12. 2001..Data obtained will form the basis of future clinical investigations to improve clinical care for PAD patients in the USA...
Clinical significance of a high ankle-brachial index: insights from the Atherosclerosis Risk in Communities (ARIC) StudyKeattiyoat Wattanakit
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 55454, USA
Atherosclerosis 190:459-64. 2007..The clinical significance of a high ankle-brachial index (ABI), defined by the associated risk factor burden and ischemic risk, is largely unknown...
Current use of aspirin and antithrombotic agents in the United States among outpatients with atherothrombotic disease (from the REduction of Atherothrombosis for Continued Health [REACH] Registry)Christopher P Cannon
TIMI Study Group, Cardiovascular Division, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 105:445-52. 2010..In conclusion, approximately 1/4 of US patients with vascular disease are not treated with aspirin for secondary prevention, and 15% are not treated with any antithrombotic agent...
A high ankle-brachial index is associated with increased cardiovascular disease morbidity and lower quality of lifeMatthew A Allison
Department of Family and Preventive Medicine, University of California San Diego, California, USA
J Am Coll Cardiol 51:1292-8. 2008..The purpose of this study is to determine if an ankle-brachial index (ABI) >or=1.40 is associated with reduced quality of life (QoL)...
The impact of peripheral arterial disease on health-related quality of life in the Peripheral Arterial Disease Awareness, Risk, and Treatment: New Resources for Survival (PARTNERS) ProgramJudith G Regensteiner
Department of Medicine, University of Colorado School of Medicine, Denver, CO 80262, USA
Vasc Med 13:15-24. 2008....
Risk factor profile and management of cerebrovascular patients in the REACH RegistryJoachim Rother
Department of Neurology, Klinikum Minden, Hannover Medical School, Minden, Germany
Cerebrovasc Dis 25:366-74. 2008..We assessed these factors in 18,992 CVD patients within a worldwide registry of stable outpatients...
International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosisDeepak L Bhatt
Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
JAMA 295:180-9. 2006..To date, no single international database has characterized the atherosclerosis risk factor profile or treatment intensity of individuals with atherothrombosis...
Cost-effectiveness of exercise training to improve claudication symptoms in patients with peripheral arterial diseaseCharoen Treesak
Faculty of Pharmacy, Srinakharinwirot University, Thailand
Vasc Med 9:279-85. 2004..The cost-effectiveness and availability of claudication treatments has national implications for future PAD care; however, data to inform these care choices can best be obtained in prospective clinical trials...
Critical issues in peripheral arterial disease detection and management: a call to actionJill J F Belch
Department of Medicine, Ninewells Hospitals and Medical School, Scotland
Arch Intern Med 163:884-92. 2003
Treatment of intermittent claudication with beraprost sodium, an orally active prostaglandin I2 analogue: a double-blinded, randomized, controlled trialEmile R Mohler
University of Pennsylvania School of Medicine, Philadelphia Heart Institute, Room 432, 51 North 39th Street, Philadelphia, PA 19104, USA
J Am Coll Cardiol 41:1679-86. 2003..In the current study, we hypothesized that beraprost would: 1) improve treadmill exercise performance and quality of life; and 2) decrease rates of ischemic events in patients with intermittent claudication...
Exercise training for claudicationKerry J Stewart
Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, USA
N Engl J Med 347:1941-51. 2002
Concomitant peripheral arterial disease and coronary artery disease: therapeutic opportunitiesJohn A Bittl
Ocala Heart Institute, Munroe Regional Medical Center, Ocala, Fla 34474, USA
Circulation 109:3136-44. 2004
Peripheral arterial disease rehabilitation: a reviewRita A Falcone
Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Cardiopulm Rehabil 23:170-5. 2003
The Claudication: Exercise Vs. Endoluminal Revascularization (CLEVER) study: rationale and methodsTimothy P Murphy
Rhode Island Hospital Vascular Disease Research Center and Brown Medical School Department of Diagnostic Imaging, Providence, RI 02903, USA
J Vasc Surg 47:1356-63. 2008....
Amplified benefit of clopidogrel versus aspirin in patients with diabetes mellitusDeepak L Bhatt
Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Am J Cardiol 90:625-8. 2002
Peripheral arterial disease: medical care and prevention of complicationsDavid L Dawson
Uniformed Services University of the Health Sciences, Bethesda, MD, USA
Prev Cardiol 5:119-30. 2002..When diagnosed early, both exercise and pharmacotherapy can ameliorate symptoms of claudication, augment functional performance, and improve quality of life...
The continuum of risk: vascular pathophysiology, function, and structureAlan T Hirsch
Circulation 110:2774-7. 2004
Development of a multicenter peripheral arterial interventional database: the PVD-QI2Debabrata Mukherjee
Gill Heart Institute, Division of Cardiovascular Medicine, Lexington, KY 40436-0200, USA
Am Heart J 149:1003-8. 2005....
ACC/AHA 2005 guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic): executive summary a collaborative report from the American Association for Vascular Surgery/Society for VasAlan T Hirsch
J Am Coll Cardiol 47:1239-312. 2006
"POBA Plus": will the balloon regain its luster?Timothy D Henry
Circulation 118:1309-11. 2008
Atherosclerotic risk factor reduction in peripheral arterial diseasea: results of a national physician surveyMary Mcgrae McDermott
Departments of Medicine and Preventive Medicine, The Feinberg School of Medicine, Northwestern University, Evanston Ill 60611, USA
J Gen Intern Med 17:895-904. 2002..We documented physician-reported practice behavior, knowledge, and attitudes regarding atherosclerotic risk factor reduction in patients with PAD...
Usefulness of increased skin cholesterol to identify individuals at increased cardiovascular risk (from the Predictor of Advanced Subclinical Atherosclerosis study)James H Stein
University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
Am J Cardiol 101:986-91. 2008..SC may be a useful test for cardiovascular risk prediction...
Regional Angiogenesis with Vascular Endothelial Growth Factor (VEGF) in peripheral arterial disease: Design of the RAVE trialSanjay Rajagopalan
Department of Internal Medicine, Section of Vascular Medicine, Division of Cardiology, University of Michigan Health System, Ann Arbor 48109 0273, USA
Am Heart J 145:1114-8. 2003..10)) to patients with severe IC caused by infrainguinal disease...
Benefit of clopidogrel over aspirin is amplified in patients with a history of ischemic eventsPeter A Ringleb
Department of Neurology, University of Heidelberg Medical School, Heidelberg, Germany
Stroke 35:528-32. 2004..039). CONCLUSIONS: CAPRIE patients with a history of prior symptomatic atherosclerotic disease had a high rate of subsequent ischemic events. The absolute benefit of clopidogrel over ASA seemed to be amplified in such high-risk patients...
ACC/AHA 2005 Practice Guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic): a collaborative report from the American Association for Vascular Surgery/Society for Vascular SurAlan T Hirsch
Circulation 113:e463-654. 2006
The REduction of Atherothrombosis for Continued Health (REACH) Registry: an international, prospective, observational investigation in subjects at risk for atherothrombotic events-study designE Magnus Ohman
Division of Cardiology, Duke University Medical Center, Durham, NC, USA
Am Heart J 151:786.e1-10. 2006....
Treatment of peripheral arterial disease--extending "intervention" to "therapeutic choice"Alan T Hirsch
N Engl J Med 354:1944-7. 2006
ACC/AHA Guidelines for the Management of Patients with Peripheral Arterial Disease (lower extremity, renal, mesenteric, and abdominal aortic): a collaborative report from the American Associations for Vascular Surgery/Society for Vascular Surgery, SocietyAlan T Hirsch
J Vasc Interv Radiol 17:1383-97; quiz 1398. 2006
Impact of carotid endarterectomy on medical secondary prevention after a stroke or a transient ischemic attack: results from the Reduction of Atherothrombosis for Continued Health (REACH) registryEmmanuel Touze
Faculté de Médecine René Descartes, Universite Paris 5, EA 4055, Department of Neurology, Paris, France
Stroke 37:2880-5. 2006..Whether a history of carotid endarterectomy influences patient compliance with medical treatments and physician attitude toward treatments after ischemic stroke or transient ischemic attack (TIA) is not well known...
One-year cardiovascular event rates in outpatients with atherothrombosisPh Gabriel Steg
Departement de Cardiologie, Hopital Bichat Claude Bernard, Paris, France
JAMA 297:1197-206. 2007....
Utility and barriers to performance of the ankle-brachial index in primary care practiceEmile R Mohler
University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Vasc Med 9:253-60. 2004..The ABI is a simple peripheral arterial disease detection tool that can be successfully applied in primary care office practices...
Randomized trial of AT-1015 for treatment of intermittent claudication. A novel 5-hydroxytryptamine antagonist with no evidence of efficacyWilliam R Hiatt
Department of Medicine, University of Colorado School of Medicine, Section of Vascular Medicine, and the Colorado Prevention Center, Denver, CO 80203, USA
Vasc Med 9:18-25. 2004..These data indicate that selective serotonin receptor blockade does not improve exercise tolerance or quality of life in individuals with claudication...
Atherosclerotic Vascular Disease Conference: Writing Group V: medical decision making and therapyMark A Creager
Circulation 109:2634-42. 2004
Carotid intima-media thickness testing by non-sonographer clinicians: the office practice assessment of carotid atherosclerosis studyClaudia E Korcarz
University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
J Am Soc Echocardiogr 21:117-22. 2008....
