Research Topics
Genomes and GenesSpecies | Joseph A HimleSummaryAffiliation: University of Michigan Country: USA Publications
Research Grants
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Detail Information
Publications
Prototype awareness enhancing and monitoring device for trichotillomaniaJoseph A Himle
The University of Michigan, Department of Psychiatry, Ann Arbor, MI 48105, USA
Behav Res Ther 46:1187-91. 2008..Semi-structured interviews revealed that the device was very effective in enhancing awareness and monitoring of trichotillomania related behaviors and enthusiastic acceptance of the device was provided by all participants...- Religious involvement and obsessive compulsive disorder among African Americans and Black CaribbeansJoseph A Himle
School of Social Work, Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, United States
J Anxiety Disord 26:502-10. 2012..With regard to demographic factors, persons of older age and higher education levels were significantly less likely to have OCD... 
Videoconferencing-based cognitive-behavioral therapy for obsessive-compulsive disorderJoseph A Himle
The University of Michigan Department of Psychiatry, 2101 Commonwealth Ave, Ann Arbor, MI 48105, USA
Behav Res Ther 44:1821-9. 2006..This pilot study suggests that videoconferencing-based CBT is a promising method to bring appropriate treatment to thousands who live far distances from well-trained therapists...- Group behavioral therapy for adolescents with tic-related and non-tic-related obsessive-compulsive disorderJoseph A Himle
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109 0840, USA
Depress Anxiety 17:73-7. 2003..Outcomes were similar for subjects with tic-related and non-tic-related OCD. These preliminary results suggest that the presence of comorbid tic disorders may not attenuate response to behavioral group treatment among adolescents... - Obsessive-compulsive disorder among African Americans and blacks of Caribbean descent: results from the National Survey of American LifeJoseph A Himle
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109 5763, USA
Depress Anxiety 25:993-1005. 2008..This is the first comprehensive examination of OCD among African Americans and blacks of Caribbean descent... - Anxiety disorders among African Americans, blacks of Caribbean descent, and non-Hispanic whites in the United StatesJoseph A Himle
University of Michigan School of Social Work, Ann Arbor, MI 48109 5763, United States
J Anxiety Disord 23:578-90. 2009..These results can be used to inform targeted interventions to prevent or remediate anxiety disorders among these diverse groups... 
Evidence for a susceptibility locus on chromosome 10p15 in early-onset obsessive-compulsive disorderGregory L Hanna
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48105, USA
Biol Psychiatry 62:856-62. 2007..The goal of this study was to identify chromosomal regions likely to contain susceptibility loci for obsessive-compulsive disorder (OCD)...- Hyperactive error responses and altered connectivity in ventromedial and frontoinsular cortices in obsessive-compulsive disorderEmily R Stern
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109, USA
Biol Psychiatry 69:583-91. 2011..While OCD has been associated with an increased neural response to errors, the influence of motivational factors on this effect remains poorly understood... - Association studies of serotonin system candidate genes in early-onset obsessive-compulsive disorderDiane E Dickel
Institute of Juvenile Research, Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois, USA
Biol Psychiatry 61:322-9. 2007..Early-onset OCD is a more familial form of the disorder... - Chronic medication does not affect hyperactive error responses in obsessive-compulsive disorderEmily R Stern
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48106, USA
Psychophysiology 47:913-20. 2010..The absence in patients of a relationship between ERN amplitude and anxiety/depression, as was found in controls, suggests that elevated error signals in OCD may be disorder-specific... - Emotional support, negative interaction and DSM IV lifetime disorders among older African Americans: findings from the National Survey of American Life (NSAL)Karen D Lincoln
School of Social Work, University of Southern California, Los Angeles, CA, USA
Int J Geriatr Psychiatry 25:612-21. 2010..This study investigated the relationship between emotional support and negative interaction on lifetime prevalence of mood and anxiety disorders among older African Americans... - Familial and sporadic subtypes of early-onset Obsessive-Compulsive disorderGregory L Hanna
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48105, USA
Biol Psychiatry 57:895-900. 2005..This study was done to determine whether there are differences between familial and sporadic probands with early-onset OCD in obsessive-compulsive (OC) symptom categories and comorbid psychiatric diagnoses... - Medial frontal cortex activity and loss-related responses to errorsStephan F Taylor
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109, USA
J Neurosci 26:4063-70. 2006..The findings support the hypothesis that the rostral extent of the MFC (rACC) processes loss-related responses to errors, and individual differences may account for some of the reported variation of error-related foci in the MFC... - Complex segregation analysis of obsessive-compulsive disorder in families with pediatric probandsGregory L Hanna
Department of Psychiatry, University of Michigan Medical School, Ann Arbor, 48109, USA
Hum Hered 60:1-9. 2005..The purpose of this study was to assess the mode of inheritance for obsessive-compulsive disorder (OCD) in families ascertained through pediatric probands... - Genome-wide linkage analysis of obsessive-compulsive disorder implicates chromosome 1p36Carol A Mathews
Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94143 0984, USA
Biol Psychiatry 72:629-36. 2012..However, the genetic causes of OCD are largely unknown, despite the identification of several promising candidate genes and linkage regions... - A family study of obsessive-compulsive disorder with pediatric probandsGregory L Hanna
Department of Psychiatry, University of Michigan Medical School, Ann Arbor, Michigan 48109 0390, USA
Am J Med Genet B Neuropsychiatr Genet 134:13-9. 2005..1% vs. 20.9%, P < 0.01). The results provide further evidence that early-onset OCD is highly familial and suggest that two clinical variables are associated with its familial aggregation... - Obsessive-compulsive disorder with and without tics in a clinical sample of children and adolescentsGregory L Hanna
Department of Psychiatry, Division of Child and Adolescent Psychiatry, University of Michigan Health System, University of Michigan, Ann Arbor, Michigan 48109-0390, USA
Depress Anxiety 16:59-63. 2002..The results indicate that tic-related OCD may be differentiated from non-tic-related OCD early in life by the presence or absence of certain compulsive symptoms... - Major depressive disorder in a family study of obsessive-compulsive disorder with pediatric probandsGregory L Hanna
Department of Psychiatry, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
Depress Anxiety 28:501-8. 2011..This study examined the comorbidity of obsessive-compulsive disorder (OCD) with major depressive disorder (MDD) in a family study of OCD with pediatric probands... - Functional studies and rare variant screening of SLC1A1/EAAC1 in males with obsessive-compulsive disorderJeremy Veenstra-Vanderweele
Department of Psychiatry, University of Vanderbilt, Nashville, Tennessee, USA
Psychiatr Genet 22:256-60. 2012..0001) in transfected human embryonic kidney cells. Further work will be necessary to understand the impact of this rare SLC1A1/EAAC1 Ala164 variant on neuronal function and circuitry relevant to OCD... - Panic disorder among African Americans, Caribbean blacks and non-Hispanic whitesDebra Siegel Levine
University of Michigan, Ann Arbor 500 S State St, Ann Arbor, MI, 48109, USA
Soc Psychiatry Psychiatr Epidemiol 48:711-23. 2013..This study investigated co-morbidities, level of disability, service utilization and demographic correlates of panic disorder (PD) among African Americans, Caribbean blacks and non-Hispanic white Americans... - Error-related hyperactivity of the anterior cingulate cortex in obsessive-compulsive disorderKate Dimond Fitzgerald
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, 48109-0118, USA
Biol Psychiatry 57:287-94. 2005..Activity in this region was positively correlated with symptom severity in the patients. CONCLUSIONS: Error-processing abnormalities within the rostral anterior cingulate occur in the absence of symptom expression in patients with OCD... - Genome-wide linkage analysis of families with obsessive-compulsive disorder ascertained through pediatric probandsGregory L Hanna
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109 0390, USA
Am J Med Genet 114:541-52. 2002..73 on 19q. The maximum multipoint LOD score with a recessive model was 1.40 on 6p. The results provide suggestive evidence for linkage on 9p and identify regions requiring further study with much larger samples... - Association testing of the positional and functional candidate gene SLC1A1/EAAC1 in early-onset obsessive-compulsive disorderDiane E Dickel
Department of Human Genetics, University of Chicago, Chicago, IL, USA
Arch Gen Psychiatry 63:778-85. 2006.... - Comparison of behavioral and cognitive-behavioral one-session exposure treatments for small animal phobiasEllen I Koch
Department of Psychology, Western Michigan University, Kalamazoo, MI 49008, USA
Behav Res Ther 42:1483-504. 2004..The programmed generalization condition did not produce additional measured benefit. The results are discussed in terms of the overall effectiveness of one-session exposure treatment components for small animal phobias...
Research Grants
- Awareness Enhancement and Monitoring Device for Treatment of TrichotillomaniaJoseph Himle; Fiscal Year: 2007..Available psychological treatments are only partially helpful and this device when integrated with current treatments could substantially improve the lives of sufferers and their families. ..