Ansel T Hillmer

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. doi request reprint Changes in the α4β2* nicotinic acetylcholine system during chronic controlled alcohol exposure in nonhuman primates
    Ansel T Hillmer
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin, Madison, 1500 Highland Avenue, Madison, WI 53705, United States Department of Medical Physics, University of Wisconsin, Madison, 1111 Highland Avenue, Madison, WI 53705, United States Electronic address
    Drug Alcohol Depend 138:216-9. 2014
  2. pmc PET imaging of α4β2* nicotinic acetylcholine receptors: quantitative analysis of 18F-nifene kinetics in the nonhuman primate
    Ansel T Hillmer
    Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    J Nucl Med 53:1471-80. 2012
  3. pmc The effects of lobeline on α4β2* nicotinic acetylcholine receptor binding and uptake of [(18)F]nifene in rats
    Ansel T Hillmer
    Department of Medical Physics, University of Wisconsin Madison, 1111 Highland Avenue, Room 1005, Madison, WI 53705, United States
    J Neurosci Methods 214:163-9. 2013
  4. pmc Measuring α4β2* nicotinic acetylcholine receptor density in vivo with [(18)F]nifene PET in the nonhuman primate
    Ansel T Hillmer
    1 Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin, USA 2 Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, Madison, Wisconsin, USA
    J Cereb Blood Flow Metab 33:1806-14. 2013
  5. pmc 5-HT1A sex based differences in Bmax, in vivo KD, and BPND in the nonhuman primate
    Dustin W Wooten
    Department of Medical Physics, University of Wisconsin Madison, WI 53705, USA
    Neuroimage 77:125-32. 2013
  6. pmc Serotonin transporter genotype affects serotonin 5-HT1A binding in primates
    Bradley T Christian
    Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    J Neurosci 33:2512-6. 2013
  7. pmc PET imaging of acetylcholinesterase inhibitor-induced effects on α4β2 nicotinic acetylcholine receptor binding
    Ansel T Hillmer
    Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin, 53705 Waisman Brain Imaging Laboratory, University of Wisconsin Madison, Madison, Wisconsin, 53705
    Synapse 67:882-6. 2013
  8. pmc Measurement of 5-HT(1A) receptor density and in-vivo binding parameters of [(18)F]mefway in the nonhuman primate
    Dustin W Wooten
    Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    J Cereb Blood Flow Metab 32:1546-58. 2012
  9. doi request reprint Amyloid burden and neural function in people at risk for Alzheimer's Disease
    Sterling C Johnson
    Geriatric Research Education and Clinical Center, Wm S Middleton Memorial VA Hospital, Madison, WI, USA Alzheimer s Disease Research Center, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA Wisconsin Alzheimer s Institute, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA Electronic address
    Neurobiol Aging 35:576-84. 2014

Collaborators

Detail Information

Publications9

  1. doi request reprint Changes in the α4β2* nicotinic acetylcholine system during chronic controlled alcohol exposure in nonhuman primates
    Ansel T Hillmer
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin, Madison, 1500 Highland Avenue, Madison, WI 53705, United States Department of Medical Physics, University of Wisconsin, Madison, 1111 Highland Avenue, Madison, WI 53705, United States Electronic address
    Drug Alcohol Depend 138:216-9. 2014
    ..The present work used PET imaging to assay α4β2* nAChR binding levels of eight rhesus monkeys before and during controlled chronic ethanol intake...
  2. pmc PET imaging of α4β2* nicotinic acetylcholine receptors: quantitative analysis of 18F-nifene kinetics in the nonhuman primate
    Ansel T Hillmer
    Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    J Nucl Med 53:1471-80. 2012
    ..The goal of this work was to analyze the in vivo kinetic properties of (18)F-nifene with both kinetic modeling and graphical analysis techniques...
  3. pmc The effects of lobeline on α4β2* nicotinic acetylcholine receptor binding and uptake of [(18)F]nifene in rats
    Ansel T Hillmer
    Department of Medical Physics, University of Wisconsin Madison, 1111 Highland Avenue, Room 1005, Madison, WI 53705, United States
    J Neurosci Methods 214:163-9. 2013
    ..Similar experiments could be used to study other drugs as therapeutic agents for smoking cessation with PET...
  4. pmc Measuring α4β2* nicotinic acetylcholine receptor density in vivo with [(18)F]nifene PET in the nonhuman primate
    Ansel T Hillmer
    1 Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin, USA 2 Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, Madison, Wisconsin, USA
    J Cereb Blood Flow Metab 33:1806-14. 2013
    ..These findings show the utility of [(18)F]nifene for measuring α4β2* nAChR Bmax in vivo in the rhesus monkey with a single PET experiment. ..
  5. pmc 5-HT1A sex based differences in Bmax, in vivo KD, and BPND in the nonhuman primate
    Dustin W Wooten
    Department of Medical Physics, University of Wisconsin Madison, WI 53705, USA
    Neuroimage 77:125-32. 2013
    ..In this work, we use a multiple-injection (MI) PET protocol and the 5-HT1A receptor antagonist, [(18)F]mefway, to compare sex-based differences of in vivo affinity, Bmax, and BPND in rhesus monkeys...
  6. pmc Serotonin transporter genotype affects serotonin 5-HT1A binding in primates
    Bradley T Christian
    Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    J Neurosci 33:2512-6. 2013
    ....
  7. pmc PET imaging of acetylcholinesterase inhibitor-induced effects on α4β2 nicotinic acetylcholine receptor binding
    Ansel T Hillmer
    Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin, 53705 Waisman Brain Imaging Laboratory, University of Wisconsin Madison, Madison, Wisconsin, 53705
    Synapse 67:882-6. 2013
    ..This preliminary work indicates the viability of [(18) F]nifene in detecting increases in synaptic ACh induced by AChEIs...
  8. pmc Measurement of 5-HT(1A) receptor density and in-vivo binding parameters of [(18)F]mefway in the nonhuman primate
    Dustin W Wooten
    Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    J Cereb Blood Flow Metab 32:1546-58. 2012
    ..The K(Dapp) of mefway for the 5-HT(1A) receptor sites was 4.3±1.3 nmol/L. In conclusion, these results show that M-I [(18)F]mefway PET experiments can be used for the in-vivo measurement of 5-HT(1A) receptor density...
  9. doi request reprint Amyloid burden and neural function in people at risk for Alzheimer's Disease
    Sterling C Johnson
    Geriatric Research Education and Clinical Center, Wm S Middleton Memorial VA Hospital, Madison, WI, USA Alzheimer s Disease Research Center, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA Wisconsin Alzheimer s Institute, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA Electronic address
    Neurobiol Aging 35:576-84. 2014
    ..This asymptomatic stage may be an opportune window for intervention to prevent progression to symptomatic AD. ..