Harry R Hill

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. pmc Profiling anti-cyclic citrullinated peptide antibodies in patients with juvenile idiopathic arthritis
    Anne E Tebo
    Department of Pediatrics and Human Genetics, Emory University School of Medicine, 2015 Uppergate Drive NE, Atlanta, GA, 30322, USA
    Pediatr Rheumatol Online J 10:29. 2012
  2. doi request reprint An update on clinical immunology, immune mechanisms and deficiency diseases
    Harry R Hill
    Department of Pathology, Pediatrics and Medicine, University of Utah, Salt Lake City, UT 84132, USA
    Expert Rev Clin Immunol 8:729-31. 2012
  3. pmc Different doses of supplemental vitamin D maintain interleukin-5 without altering skeletal muscle strength: a randomized, double-blind, placebo-controlled study in vitamin D sufficient adults
    Tyler Barker
    The Orthopedic Specialty Hospital, Murray, UT, 84107, USA
    Nutr Metab (Lond) 9:16. 2012
  4. pmc Rapid genetic analysis of x-linked chronic granulomatous disease by high-resolution melting
    Harry R Hill
    Department of Pathology, Pediatrics and Medicine, 5B114, University of Utah School of Medicine, 50 N Medical Dr, Salt Lake City, UT 84132, USA
    J Mol Diagn 12:368-76. 2010
  5. doi request reprint Comprehensive analysis of antibody responses to streptococcal and tissue antigens in patients with acute rheumatic fever
    Thomas B Martins
    Associated Regional and University Pathologists Institute for Clinical and Experimental Pathology, Salt Lake City, UT, USA
    Int Immunol 20:445-52. 2008
  6. ncbi request reprint Evaluation of a multiplex fluorescent microsphere immunoassay for the determination of epstein-barr virus serologic status
    Thomas B Martins
    Associated Regional and University Pathologists ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, UT 84108, USA
    Am J Clin Pathol 129:34-41. 2008
  7. ncbi request reprint Development of a multiplexed fluorescent immunoassay for the quantitation of antibody responses to group A streptococci
    Thomas B Martins
    Associated Regional and University Pathologists ARUP Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    J Immunol Methods 316:97-106. 2006
  8. doi request reprint Autoantibodies against phosphatidylserine, prothrombin and phosphatidylserine-prothrombin complex: identical or distinct diagnostic tools for antiphospholipid syndrome?
    Troy D Jaskowski
    Associated Regional and University Pathologists ARUP Institute for Clinical and Experimental Pathology, University of Utah School of Medicine, Salt Lake City, UT, United States
    Clin Chim Acta 410:19-24. 2009
  9. doi request reprint Multiplex analysis of toll-like receptor-stimulated neonatal cytokine response
    Justin E Caron
    Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    Neonatology 97:266-73. 2010
  10. pmc Evaluations of commercial West Nile virus immunoglobulin G (IgG) and IgM enzyme immunoassays show the value of continuous validation
    Annette K Malan
    Associated Regional and University Pathologists Institute for Clinical and Experimental Pathology, Salt Lake City, Utah 84108, USA
    J Clin Microbiol 42:727-33. 2004

Collaborators

Detail Information

Publications62

  1. pmc Profiling anti-cyclic citrullinated peptide antibodies in patients with juvenile idiopathic arthritis
    Anne E Tebo
    Department of Pediatrics and Human Genetics, Emory University School of Medicine, 2015 Uppergate Drive NE, Atlanta, GA, 30322, USA
    Pediatr Rheumatol Online J 10:29. 2012
    ..abstract:..
  2. doi request reprint An update on clinical immunology, immune mechanisms and deficiency diseases
    Harry R Hill
    Department of Pathology, Pediatrics and Medicine, University of Utah, Salt Lake City, UT 84132, USA
    Expert Rev Clin Immunol 8:729-31. 2012
    ....
  3. pmc Different doses of supplemental vitamin D maintain interleukin-5 without altering skeletal muscle strength: a randomized, double-blind, placebo-controlled study in vitamin D sufficient adults
    Tyler Barker
    The Orthopedic Specialty Hospital, Murray, UT, 84107, USA
    Nutr Metab (Lond) 9:16. 2012
    ..abstract:..
  4. pmc Rapid genetic analysis of x-linked chronic granulomatous disease by high-resolution melting
    Harry R Hill
    Department of Pathology, Pediatrics and Medicine, 5B114, University of Utah School of Medicine, 50 N Medical Dr, Salt Lake City, UT 84132, USA
    J Mol Diagn 12:368-76. 2010
    ..High-resolution melting can provide timely diagnosis at low cost for effective clinical management of rare, genetic primary immunodeficiency disorders...
  5. doi request reprint Comprehensive analysis of antibody responses to streptococcal and tissue antigens in patients with acute rheumatic fever
    Thomas B Martins
    Associated Regional and University Pathologists Institute for Clinical and Experimental Pathology, Salt Lake City, UT, USA
    Int Immunol 20:445-52. 2008
    ..The major differences between the ARF patients with and without carditis appear to be in the immune response to the putative heart valve components, collagen I and fibronectin...
  6. ncbi request reprint Evaluation of a multiplex fluorescent microsphere immunoassay for the determination of epstein-barr virus serologic status
    Thomas B Martins
    Associated Regional and University Pathologists ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, UT 84108, USA
    Am J Clin Pathol 129:34-41. 2008
    ..Advantages of the multiplex assay over traditional methods include multiple results per assay, inclusion of internal controls for each assay, and well-to-well monitoring of assay drift...
  7. ncbi request reprint Development of a multiplexed fluorescent immunoassay for the quantitation of antibody responses to group A streptococci
    Thomas B Martins
    Associated Regional and University Pathologists ARUP Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    J Immunol Methods 316:97-106. 2006
    ....
  8. doi request reprint Autoantibodies against phosphatidylserine, prothrombin and phosphatidylserine-prothrombin complex: identical or distinct diagnostic tools for antiphospholipid syndrome?
    Troy D Jaskowski
    Associated Regional and University Pathologists ARUP Institute for Clinical and Experimental Pathology, University of Utah School of Medicine, Salt Lake City, UT, United States
    Clin Chim Acta 410:19-24. 2009
    ....
  9. doi request reprint Multiplex analysis of toll-like receptor-stimulated neonatal cytokine response
    Justin E Caron
    Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    Neonatology 97:266-73. 2010
    ..Toll-like receptors (TLRs) have been recognized as pattern-recognition receptors critical to the innate immune response. TLR function in neonates, however, remains incompletely defined...
  10. pmc Evaluations of commercial West Nile virus immunoglobulin G (IgG) and IgM enzyme immunoassays show the value of continuous validation
    Annette K Malan
    Associated Regional and University Pathologists Institute for Clinical and Experimental Pathology, Salt Lake City, Utah 84108, USA
    J Clin Microbiol 42:727-33. 2004
    ..5% with the Focus West Nile virus IgM-capture ELISA. This experience demonstrates the importance of continuously evaluating the performance of an assay in order to detect any changes in assay performance as the test population evolves...
  11. pmc Evaluation of an enzyme immunoassay for detection of immunoglobulin M antibodies to West Nile virus and the importance of background subtraction in detecting nonspecific reactivity
    Mindy L Rawlins
    ARUP Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    Clin Vaccine Immunol 14:665-8. 2007
    ..We suggest that all WNV IgM assays be standardized with a procedure such as background subtraction to eliminate nonspecific reactivity that may cause false-positive results...
  12. ncbi request reprint Prevalence of IgG autoantibody against F-actin in patients suspected of having autoimmune or acute viral hepatitis
    Troy D Jaskowski
    Associated Regional and University Pathologists Institute for Clinical and Experimental Pathology, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA
    J Clin Lab Anal 21:249-53. 2007
    ..FAA was detected in 25% of viral hepatitis antibody-positive sera, with the majority (59.3%) containing low levels, and all were ANA-negative...
  13. doi request reprint Relationship between rheumatoid factor isotypes and IgG anti-cyclic citrullinated peptide antibodies
    Troy D Jaskowski
    Associated Regional and University Pathologists, Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, Utah 84108, USA
    J Rheumatol 37:1582-8. 2010
    ..To validate in a general patient population (GPP) the clinical value of measuring rheumatoid factor (RF) isotypes in relationship to IgG anti-cyclic citrullinated peptide (CCP) antibodies (CCP2 and CCP3)...
  14. doi request reprint Development of a multiplexed fluorescent immunoassay for the quantitation of antibody responses to four Neisseria meningitidis serogroups
    Thomas B Martins
    Associated Regional and University Pathologists ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, UT 84108, USA
    J Immunol Methods 342:98-105. 2009
    ..Advantages included a greater dynamic range and simultaneous detection of antibody responses to the four serogroups contained in the tetravalent meningococcal polysaccharide vaccine...
  15. doi request reprint Coccidioides immitis meningitis in a patient with hyperimmunoglobulin E syndrome due to a novel mutation in signal transducer and activator of transcription
    Annie E Powers
    Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    Pediatr Infect Dis J 28:664-6. 2009
    ..We report the first case of Coccidioides immitis meningitis in a patient with HIES. Coccidioides should be included in the differential diagnosis for central nervous system infections in HIES patients...
  16. pmc Comparison of two commercial enzyme-linked immunosorbent assays with an immunofluorescence assay for detection of Legionella pneumophila types 1 to 6
    Annette K Malan
    Associated Regional and University Pathologists Institute for Clinical and Experimental Pathology, Salt Lake City, Utah 84108, USA
    J Clin Microbiol 41:3060-3. 2003
    ..6, 10.5, and 100.0%, respectively. We recommend that any laboratories attempting to replace an IFA type 1 to 6 screen with an alternative ELISA carefully investigate the sensitivity of the replacement assay...
  17. ncbi request reprint Evaluation of an in vitro assay for interferon gamma production in response to the Mycobacterium tuberculosis-synthesized peptide antigens ESAT-6 and CFP-10 and the PPD skin test
    Edward W Taggart
    Associated Regional and University Pathologists Institute for Clinical and Experimental Pathology, Salt Lake City, UT 84108, USA
    Am J Clin Pathol 125:467-73. 2006
    ..0%); and QFT-G, 5 (16. 7%); and group 3: TST, 26 (100.0%); QFT, 13 (50.0%); and QFT-G, 9 (34.6%). The QFT-G demonstrated less cross-reactivity with BCG antigen and was more specific than QFT and TST in low-risk individuals...
  18. pmc Elimination of false-positive results in a luminex assay for pneumococcal antibodies
    Jerry W Pickering
    ARUP Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    Clin Vaccine Immunol 17:185-9. 2010
    ..The first group bound nonspecifically to the Luminex microspheres. The second group reacted specifically with bovine serum albumin (BSA). We describe here methods that eliminated the false-positive reactivity of both groups...
  19. ncbi request reprint The flow cytometric analysis of cytokines using multi-analyte fluorescence microarray technology
    Harry R Hill
    ARUP Institute for Clinical and Experimental Pathology, Department of Pathology, Pediatrics and Medicine, University of Utah School of Medicine, Salt Lake City, USA
    Methods 38:312-6. 2006
    ....
  20. doi request reprint Myth and reality: practical test system for the measurement of anti-DNA antibodies in the diagnosis of systemic lupus erythematosus (SLE)
    Laura J McCloskey
    Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107 4998, USA
    J Clin Lab Anal 24:77-84. 2010
    ....
  21. doi request reprint Diagnostic performance of phospholipid-specific assays for the evaluation of antiphospholipid syndrome
    Anne E Tebo
    Associated Regional and University Pathologists, Institute for Clinical and Experimental Pathology, University of Utah School of Medicine, Salt Lake City, USA
    Am J Clin Pathol 129:870-5. 2008
    ..01) and aPS (P = .02) antibodies. Overall, the combined sensitivity of the aPL assays differed significantly between manufacturers and did not improve the diagnostic yield for APS...
  22. doi request reprint Analysis of proinflammatory and anti-inflammatory cytokine serum concentrations in patients with multiple sclerosis by using a multiplexed immunoassay
    Thomas B Martins
    ARUP Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    Am J Clin Pathol 136:696-704. 2011
    ....
  23. ncbi request reprint Further comparisons of assays for detecting MAG IgM autoantibodies
    Troy D Jaskowski
    Associated Regional and University Pathologists ARUP, Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    J Neuroimmunol 187:175-8. 2007
    ..Patients having low titers by EIA, but negative by WB may have other autoimmune neuropathies without demyelination...
  24. pmc Evolving epidemiologic characteristics of invasive group a streptococcal disease in Utah, 2002-2010
    Chris Stockmann
    Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City, 84108, USA
    Clin Infect Dis 55:479-87. 2012
    ..Invasive group A Streptococcus (GAS) infections are associated with substantial morbidity and mortality. Recent national surveillance data report stable rates of invasive GAS disease, although these may not capture geographic variation...
  25. ncbi request reprint Comparison of immunofluorescence antibody testing and two enzyme immunoassays in the serologic diagnosis of malaria
    Rosemary C She
    Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    J Travel Med 14:105-11. 2007
    ..Serologic testing in malaria has traditionally been done by immunofluorescence antibody testing (IFA), but the use of commercially available enzyme immunoassays (EIAs) has become more widespread...
  26. ncbi request reprint Antibody responses to group A streptococcal infections in acute rheumatic fever
    Thomas B Martins
    Associated Regional and University Pathologists ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah 84108, USA
    Pediatr Infect Dis J 25:832-7. 2006
  27. pmc Evaluation of multiplexed fluorescent microsphere immunoassay for detection of autoantibodies to nuclear antigens
    Thomas B Martins
    Associated Regional and University Pathologists Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    Clin Diagn Lab Immunol 11:1054-9. 2004
    ..Our studies show that the multiplexed microsphere-based immunoassay is a sensitive and specific method for the detection and semiquantitation of ENA antibodies in human sera...
  28. pmc D8/17 and CD19 expression on lymphocytes of patients with acute rheumatic fever and Tourette's disorder
    Julie L Weisz
    Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    Clin Diagn Lab Immunol 11:330-6. 2004
    ....
  29. ncbi request reprint Serological diagnosis of Trypanosoma cruzi: evaluation of three enzyme immunoassays and an indirect immunofluorescent assay
    Annette K Malan
    Associated Regional and University Pathologists, Institute for Clinical and Experimental Pathology, University of Utah, Salt Lake City, Utah, USA
    J Med Microbiol 55:171-8. 2006
    ..The CeLLabs and Hemagen IgG ELISAs had 100 % agreement, sensitivity and specificity. The IVD Research IgG ELISA had 94.6 % agreement, 100 % sensitivity and 93 % specificity...
  30. pmc Heterophile antibody interference in a multiplexed fluorescent microsphere immunoassay for quantitation of cytokines in human serum
    Thomas B Martins
    Associated Regional and University Pathologists Institute for Clinical and Experimental Pathology, Salt Lake City, Utah 84108, USA
    Clin Diagn Lab Immunol 11:325-9. 2004
    ..The fluorescent multiplexed microsphere-based immunoassay can be used to quantitate multiple cytokines from a single sample and should be a useful tool in furthering our understanding of the role of cytokines in disease processes...
  31. ncbi request reprint Temporal association of the appearance of mucoid strains of Streptococcus pyogenes with a continuing high incidence of rheumatic fever in Utah
    L George Veasy
    Department of Pediatrics, University of Utah School of Medicine, Primary Children s Medical Center, Salt Lake City, Utah 84113, USA george veasy hsc utah edu
    Pediatrics 113:e168-72. 2004
    ..During the initial outbreak and the later exacerbation of the resurgence, an increased number of mucoid strains of S pyogenes were present in the community...
  32. ncbi request reprint Comparison of complement fixation with two enzyme-linked immunosorbent assays for the detection of antibodies to respiratory viral antigens
    Edward W Taggart
    Associated Regional and University Pathologists Institute for Clinical and Experimental Pathology, Salt Lake City, UT 84108, USA
    Am J Clin Pathol 125:460-6. 2006
    ..The influenza A and influenza B ELISA antigens differed between both kits, which may explain their poor agreement. The ELISA is a suitable replacement for CF, providing greater sensitivity, isotype specificity, and ease of use...
  33. pmc Comparison of a multiplexed herpes simplex virus type-specific immunoglobulin G serology assay to immunoblot, Western blot, and enzyme-linked immunosorbent assays
    Thomas B Martins
    ARUP Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    Clin Vaccine Immunol 16:55-60. 2009
    ..Advantages of the multiplex assay include multiple results per assay, the inclusion of internal controls for each specimen, and higher throughput of results...
  34. doi request reprint Diagnostic assays for anti-PM/Scl IgG antibodies: heterogeneity in antibody response or lack of standardization?
    Troy D Jaskowski
    Associated Regional and University Pathologists ARUP Institute for Clinical and Experimental Pathology, University of Utah School of Medicine, Salt Lake City, UT 84108 1221, United States
    Clin Chim Acta 412:1100-5. 2011
    ....
  35. doi request reprint Family clusters of variant X-linked chronic granulomatous disease
    Jeffrey M Bender
    Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Pediatr Infect Dis J 28:529-33. 2009
    ..A high index of suspicion in the setting of unusual infections such as Burkholderia cepacia pneumonia is essential to make the diagnosis. Family screening can lead to early intervention, prophylaxis, and appropriate genetic counseling...
  36. pmc Evaluation of an in vitro assay for gamma interferon production in response to Mycobacterium tuberculosis infections
    Edward W Taggart
    ARUP Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    Clin Diagn Lab Immunol 11:1089-93. 2004
    ..8%, a sensitivity of 50%, and a specificity of 98.4% compared with TST results. QFT testing with TST in low-risk groups can aid in the detection of latent M. tuberculosis infections...
  37. doi request reprint Dermatitis herpetiformis sera or goat anti-transglutaminase-3 transferred to human skin-grafted mice mimics dermatitis herpetiformis immunopathology
    John J Zone
    Department of Dermatology, University of Utah, Salt Lake City, UT 84112, USA
    J Immunol 186:4474-80. 2011
    ..These deposits seem to form over weeks in a process similar to an Ouchterlony immunodiffusion precipitate. This process of deposition explains the negative indirect immunofluorescence results with DH serum...
  38. ncbi request reprint Flow cytometric assay for genotyping cytochrome p450 2C9 and 2C19: comparison with a microelectronic DNA array
    Jerry W Pickering
    Associated Regional and University Pathologists, Institute for Clinical and Experimental Pathology, Salt Lake City, Utah 84108, USA
    Am J Pharmacogenomics 4:199-207. 2004
    ..To correlate the dose required for therapeutic drug efficacy with genotype, accurate and reliable methods for detecting single nucleotide polymorphisms (SNPs) of CYP2C9 and CYP2C19 are required...
  39. doi request reprint Binding of anti-HLA class I antibody to endothelial cells produce an inflammatory cytokine secretory pattern
    Eduardo Reyes-Vargas
    Department of Pathology, University of Utah, Salt Lake City, Utah 84112, USA
    J Clin Lab Anal 23:157-60. 2009
    ....
  40. pmc Analysis of serum antibodies in patients suspected of having inflammatory bowel disease
    Troy D Jaskowski
    Associated Regional and University Pathologists Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    Clin Vaccine Immunol 13:655-60. 2006
    ..0%) of these patients were more likely to have had UC or Crohn's colitis based on the presence of an atypical pANCA...
  41. ncbi request reprint A 22-plex chemiluminescent microarray for pneumococcal antibodies
    Jerry W Pickering
    Associated Regional and University Pathologists, Institute for Clinical and Experimental Pathology, Salt Lake City, UT 84108, USA
    Am J Clin Pathol 128:23-31. 2007
    ..The microarray multiplexing technology is an attractive alternative to ELISA for antibody responses to 23-valent PnPs vaccines...
  42. ncbi request reprint Comparison of ATP production in whole blood and lymphocyte proliferation in response to phytohemagglutinin
    Nancy H Augustine
    Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    J Clin Lab Anal 21:265-70. 2007
    ..However, a positive screen should always be confirmed by 3H-thy uptake using mitogens and recall antigens like candida and tetanus...
  43. pmc Detection of kappa and lambda light chain monoclonal proteins in human serum: automated immunoassay versus immunofixation electrophoresis
    Troy D Jaskowski
    Associated Regional and University Pathologists Institute for Clinical and Experimental Pathology, University of Utah School of Medicine, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    Clin Vaccine Immunol 13:277-80. 2006
    ..9 to 91.4%) than IFE, but specific in detecting serum monoclonal proteins. Moreover, the kappa/lambda ratio has little value in routine screening since the majority of sera with abnormal IFE patterns had normal kappa/lambda FLC ratios...
  44. pmc Evaluation of a western blot method for the detection of Yersinia antibodies: evidence of serological cross-reactivity between Yersinia outer membrane proteins and Borrelia burgdorferi
    Mindy L Rawlins
    Associated Regional and University Pathologists ARUP Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    Clin Diagn Lab Immunol 12:1269-74. 2005
    ..burgdorferi, which can cause an oligoarthritis similar to reactive arthritis, the diagnosis of reactive arthritis should be based on clinical findings and complete serologic analysis of the potential causative infectious pathogens...
  45. doi request reprint Screening for IgG antinuclear autoantibodies by HEp-2 indirect fluorescent antibody assays and the need for standardization
    Susan S Copple
    Associated Regional and University Pathologists Institute for Clinical and Experimental Pathology, University of Utah School of Medicine, Salt Lake City, USA
    Am J Clin Pathol 137:825-30. 2012
    ..Along with subjectivity of interpretation, HEp-2 IFA assays are also vulnerable to standardization issues similar to other methods for ANA screening...
  46. pmc Rapid molecular analysis of the STAT3 gene in Job syndrome of hyper-IgE and recurrent infectious diseases
    Attila Kumanovics
    Department of Pathology, Human Genetics, University of Utah School of Medicine and the Associated Regional and University Pathologists Institute for Clinical and Experimental Pathology, Salt Lake City, UT, USA
    J Mol Diagn 12:213-9. 2010
    ....
  47. ncbi request reprint Defective production of IL-18 and IL-12 by cord blood mononuclear cells influences the T helper-1 interferon gamma response to group B Streptococci
    Timothy R La Pine
    Department of Pathology, University of Utah School of Medicine, 50 North Medical Rm 5B114, Salt Lake City, UT 84132, U S A
    Pediatr Res 54:276-81. 2003
    ..This combined Th-1 type cytokine deficiency may contribute to the enhanced susceptibility of the human neonate to GBS and other microbial infections...
  48. doi request reprint Cell-based reporter gene assay for therapy-induced neutralizing antibodies to interferon-beta in multiple sclerosis
    Thomas B Martins
    ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, UT 84108, USA
    J Interferon Cytokine Res 33:52-7. 2013
    ..The use of this functional assay should be a valuable tool for detecting and monitoring the presence of NAbs in IFN-β-treated patients with MS...
  49. doi request reprint Diffuse large B cell lymphoma in hyper-IgE syndrome due to STAT3 mutation
    Attila Kumanovics
    Department of Pathology, University of Utah School of Medicine, 50 North Medical Drive, Salt Lake City, UT 84132, USA
    J Clin Immunol 30:886-93. 2010
    ..We review the literature regarding lymphoma in hyper-IgE syndrome and the possible etiologic relationship with STAT3 mutations...
  50. pmc Elevated serum levels of soluble CD154 in children with juvenile idiopathic arthritis
    Sampath Prahalad
    Department of Pediatrics, University of Utah, Salt Lake City, UT, USA
    Pediatr Rheumatol Online J 6:8. 2008
    ..Our objectives were to determine if sCD154 is elevated in JIA, and to examine correlations between sCD154 and other inflammatory cytokines...
  51. ncbi request reprint Comparison of three multiplex immunoassays for detection of antibodies to extractable nuclear antibodies using clinically defined sera
    Susan S Copple
    Associated Regional and University Pathologists ARUP Autoimmune Laboratory, Salt Lake City, Utah, USA
    Ann N Y Acad Sci 1109:464-72. 2007
    ..Significant variation in specificity and sensitivity due to individual characteristics of each assay was demonstrated, with the BMD assay showing the highest correlation with clinical diagnosis...
  52. doi request reprint Measurement of antibodies to pneumococcal polysaccharides with Luminex xMAP microsphere-based liquid arrays
    Jerry W Pickering
    ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, UT, USA
    Methods Mol Biol 808:361-75. 2012
    ....
  53. doi request reprint Severity of symptom flare after moderate exercise is linked to cytokine activity in chronic fatigue syndrome
    Andrea T White
    Department of Exercise and Sport Science, University of Utah, Salt Lake City, Utah, USA
    Psychophysiology 47:615-24. 2010
    ..05). Thus, in CFS, cytokine activity may vary directly with SF, which may explain prior inconsistent findings...
  54. doi request reprint Enzyme-linked immunosorbent assay screening then indirect immunofluorescence confirmation of antinuclear antibodies: a statistical analysis
    Susan S Copple
    ARUP Laboratories, Salt Lake City, UT, USA
    Am J Clin Pathol 135:678-84. 2011
    ..Samples positive by ANA ELISA should be tested on HEp-2 to determine the titer and pattern...
  55. ncbi request reprint Molecular characterization of Streptococcus pyogenes isolates collected during periods of increased acute rheumatic fever activity in Utah
    Lonnie J Miner
    Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City, UT, USA
    Pediatr Infect Dis J 23:56-61. 2004
    ..Salt Lake City, Utah has seen a continuing resurgence of rheumatic fever (RF) since 1985...
  56. ncbi request reprint Detection of IgG and IgM to West Nile virus. Development of an immunofluorescence assay
    Annette K Malan
    Associated Regional and University Pathologists ARUP, Institute for Clinical and Experimental Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA
    Am J Clin Pathol 119:508-15. 2003
    ..The IFA protocol described herein is a cost-effective and sensitive alternative to ELISA and MAC-ELISA for the serologic diagnosis of WNV infection...
  57. doi request reprint Successful use of extracorporeal membrane oxygenation for acute respiratory failure in a patient with chronic granulomatous disease
    Jesse L Madden
    Department of Surgery, Primary Children s Medical Center, Salt Lake City, UT, USA
    J Pediatr Surg 47:E21-3. 2012
    ..Therefore, the diagnosis of CGD should not necessarily be considered a contraindication to ECMO. This is the first known survivor of CGD-related acute respiratory failure supported by ECMO...
  58. pmc Significance of C-reactive protein in osteoarthritis and total knee arthroplasty outcomes
    Jessica W Smith
    Department of Bioengineering, University of Utah, 3223 Sorenson Molecular Biotechnology Building, Salt Lake City, UT 84112, USA
    Ther Adv Musculoskelet Dis 4:315-25. 2012
    ..This study investigates the relationship between serum high-sensitivity C-reactive protein (hs-CRP) and functional outcomes post-TKA...
  59. ncbi request reprint Determination of cytokine responses using a multiplexed fluorescent microsphere immunoassay
    Thomas B Martins
    Associated Regional and University Pathologists, Institute for Clinical and Experimental Pathology, Salt Lake City, UT 84108, USA
    Am J Clin Pathol 118:346-53. 2002
    ..The fluorescent multiplexed microsphere immunoassay can be used to quantitate multiple cytokines from 1 sample and should be useful for further understanding of the cytokine role in disease...
  60. ncbi request reprint A multiplexed fluorescent microsphere immunoassay for antibodies to pneumococcal capsular polysaccharides
    Jerry W Pickering
    Associated Regional and University Pathologists Institute for Clinical and Experimental Pathology, Salt Lake City, UT 84108, USA
    Am J Clin Pathol 117:589-96. 2002
    ..The multiplexed Luminex assay showed good overall agreement with a well-established enzyme-linked immunosorbent assay that is currently recommended for evaluation of pneumococcal vaccine immunogenicity...
  61. pmc Comparison of a multiplex flow cytometric assay with enzyme-linked immunosorbent assay for auantitation of antibodies to tetanus, diphtheria, and Haemophilus influenzae Type b
    Jerry W Pickering
    Associated Regional and University Pathologists, Institute for Clinical and Experimental Pathology, Salt Lake City, Utah 84108, USA
    Clin Diagn Lab Immunol 9:872-6. 2002
    ..Both methods detected strong postvaccination responses. The Luminex method is an attractive alternative to ELISA since it reduces labor and reagent costs, as well as assay time...
  62. ncbi request reprint Comparison of four enzyme immunoassays for the detection of immunoglobulin G antibody against glomerular basement membrane
    Troy D Jaskowski
    Regional and University Pathologists ARUP, Institute for Clinical and Experimental Pathology, Salt Lake City, Utah 84108, USA
    J Clin Lab Anal 16:143-5. 2002
    ..We also recommend confirming GBM EIA-positive sera by the standard IFA method using tissue from human kidney...