Aram F Hezel

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc Diabetes mellitus impacts risk of macrovascular invasion in patients undergoing transplantation for hepatocellular carcinoma
    Gregory C Connolly
    The Department of Medicine, James P, Wilmot Cancer Center, and, University of Rochester, Rochester, NY, USA
    BMC Gastroenterol 13:9. 2013
  2. pmc Mutational profiling reveals PIK3CA mutations in gallbladder carcinoma
    Vikram Deshpande
    Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, USA
    BMC Cancer 11:60. 2011
  3. pmc Genetics of biliary tract cancers and emerging targeted therapies
    Aram F Hezel
    James P Wilmot Cancer Center, University of Rochester School of Medicine, Rochester, NY 14642, USA
    J Clin Oncol 28:3531-40. 2010
  4. pmc Autophagy in intra-hepatic cholangiocarcinoma
    Jing Li Huang
    James P Wilmot Cancer Center, University of Rochester School of Medicine, Rochester, NY, USA
    Autophagy 8:1148-9. 2012
  5. pmc Kras(G12D) and p53 mutation cause primary intrahepatic cholangiocarcinoma
    Michael R O'Dell
    James P Wilmot Cancer Center, University of Rochester School of Medicine, Rochester, New York 14642, USA
    Cancer Res 72:1557-67. 2012

Collaborators

  • Andrew X Zhu
  • Nabeel Bardeesy
  • Jing Li Huang
  • Vikram Deshpande
  • Gregory C Connolly
  • Michael R O'Dell
  • Randeep Kashyap
  • Rui Chen
  • Saman Safadjou
  • Mark S Orloff
  • Hartmut Land
  • Randall M Rossi
  • Valerie Grose
  • Paul Rothberg
  • Christa L Whitney-Miller
  • Cristina Ferrone
  • Laura E MacConaill
  • Sarah M Kehoe
  • Stephanie M Zimmerman
  • Gregory Y Lauwers
  • Afamefuna Nduaguba

Detail Information

Publications5

  1. pmc Diabetes mellitus impacts risk of macrovascular invasion in patients undergoing transplantation for hepatocellular carcinoma
    Gregory C Connolly
    The Department of Medicine, James P, Wilmot Cancer Center, and, University of Rochester, Rochester, NY, USA
    BMC Gastroenterol 13:9. 2013
    ..Diabetes mellitus (DM) is identified as a negative prognostic indicator in hepatocellular carcinoma (HCC), though the basis for this is unknown...
  2. pmc Mutational profiling reveals PIK3CA mutations in gallbladder carcinoma
    Vikram Deshpande
    Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, USA
    BMC Cancer 11:60. 2011
    ..The genetics of advanced biliary tract cancers (BTC), which encompass intra- and extra-hepatic cholangiocarcinomas as well as gallbladder carcinomas, are heterogeneous and remain to be fully defined...
  3. pmc Genetics of biliary tract cancers and emerging targeted therapies
    Aram F Hezel
    James P Wilmot Cancer Center, University of Rochester School of Medicine, Rochester, NY 14642, USA
    J Clin Oncol 28:3531-40. 2010
    ..Here, we summarize the molecular pathogenesis and genetics of BTCs and animal modeling and relate these to recent and ongoing clinical trials with targeted agents...
  4. pmc Autophagy in intra-hepatic cholangiocarcinoma
    Jing Li Huang
    James P Wilmot Cancer Center, University of Rochester School of Medicine, Rochester, NY, USA
    Autophagy 8:1148-9. 2012
    ..A basic understanding of the disease has long been hampered by limited tumor cell lines and good model systems. Similarly, such limitations have obstructed new therapeutic inroads...
  5. pmc Kras(G12D) and p53 mutation cause primary intrahepatic cholangiocarcinoma
    Michael R O'Dell
    James P Wilmot Cancer Center, University of Rochester School of Medicine, Rochester, New York 14642, USA
    Cancer Res 72:1557-67. 2012
    ..These findings establish a new genetically and histopathologically faithful model of IHCC and lend experimental support to the hypothesis that IPBN and VMC are precursors to invasive cancers...