Irva Hertz-Picciotto

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Exposure to hydroxylated polychlorinated biphenyls (OH-PCBs) in the prenatal period and subsequent neurodevelopment in eastern Slovakia
    Hye Youn Park
    Division of Epidemiology, Department of Public Health Sciences, School of Medicine, University of California Davis, Davis, California, USA
    Environ Health Perspect 117:1600-6. 2009
  2. pmc Coal home heating and environmental tobacco smoke in relation to lower respiratory illness in Czech children, from birth to 3 years of age
    Rebecca J Baker
    Department of Epidemiology, School of Public Health, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, USA
    Environ Health Perspect 114:1126-32. 2006
  3. pmc Prenatal PCB exposure and thymus size at birth in neonates in Eastern Slovakia
    Hye Youn Park
    Division of Epidemiology, Department of Public Health Sciences, School of Medicine, University of California, Davis, CA 95616, USA
    Environ Health Perspect 116:104-9. 2008
  4. pmc Infant siblings and the investigation of autism risk factors
    Craig J Newschaffer
    Department of Epidemiology and Biostatistics, Drexel School of Public Health, 1505 Race Street, Mail Stop 1033, Philadelphia, PA 19102, USA
    J Neurodev Disord 4:7. 2012
  5. ncbi request reprint Air pollution and distributions of lymphocyte immunophenotypes in cord and maternal blood at delivery
    Irva Hertz-Picciotto
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
    Epidemiology 13:172-83. 2002
  6. pmc Blood mercury concentrations in CHARGE Study children with and without autism
    Irva Hertz-Picciotto
    Department of Public Health Sciences, University of California Davis, Davis, California 95616 8638, USA
    Environ Health Perspect 118:161-6. 2010
  7. ncbi request reprint In utero polychlorinated biphenyl exposures in relation to fetal and early childhood growth
    Irva Hertz-Picciotto
    Department of Epidemiology, School of Public Health, University of North Carolina Chapel Hill, Chapel Hill, NC, USA
    Epidemiology 16:648-56. 2005
  8. ncbi request reprint The rise in autism and the role of age at diagnosis
    Irva Hertz-Picciotto
    Department of Public Health Sciences, University of California, Davis, California 95616, USA
    Epidemiology 20:84-90. 2009
  9. pmc A cohort study of in utero polychlorinated biphenyl (PCB) exposures in relation to secondary sex ratio
    Irva Hertz-Picciotto
    Department of Public Health Sciences, School of Medicine, TB 168, University of California Davis, Davis, CA 95616, USA
    Environ Health 7:37. 2008
  10. pmc The CHARGE study: an epidemiologic investigation of genetic and environmental factors contributing to autism
    Irva Hertz-Picciotto
    Division of Epidemiology, Department of Public Health Sciences, School of Medicine, and Medical Investigations of Neurodevelopmental Disorders MIND Institute, University of California Davis, Davis, California, USA
    Environ Health Perspect 114:1119-25. 2006

Detail Information

Publications98

  1. pmc Exposure to hydroxylated polychlorinated biphenyls (OH-PCBs) in the prenatal period and subsequent neurodevelopment in eastern Slovakia
    Hye Youn Park
    Division of Epidemiology, Department of Public Health Sciences, School of Medicine, University of California Davis, Davis, California, USA
    Environ Health Perspect 117:1600-6. 2009
    ....
  2. pmc Coal home heating and environmental tobacco smoke in relation to lower respiratory illness in Czech children, from birth to 3 years of age
    Rebecca J Baker
    Department of Epidemiology, School of Public Health, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, USA
    Environ Health Perspect 114:1126-32. 2006
    ..The objective of this study was to evaluate how indoor pollution from tobacco and home heating may adversely affect respiratory health in young children...
  3. pmc Prenatal PCB exposure and thymus size at birth in neonates in Eastern Slovakia
    Hye Youn Park
    Division of Epidemiology, Department of Public Health Sciences, School of Medicine, University of California, Davis, CA 95616, USA
    Environ Health Perspect 116:104-9. 2008
    ..The thymus is essential for the differentiation and maturation of T-cell lymphocytes...
  4. pmc Infant siblings and the investigation of autism risk factors
    Craig J Newschaffer
    Department of Epidemiology and Biostatistics, Drexel School of Public Health, 1505 Race Street, Mail Stop 1033, Philadelphia, PA 19102, USA
    J Neurodev Disord 4:7. 2012
    ..It then discusses the key features of this approach and provides a description of the design and implementation strategy of one major ASD enriched-risk pregnancy cohort study: the Early Autism Risk Longitudinal Investigation (EARLI)...
  5. ncbi request reprint Air pollution and distributions of lymphocyte immunophenotypes in cord and maternal blood at delivery
    Irva Hertz-Picciotto
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
    Epidemiology 13:172-83. 2002
    ..Heavy air pollution may affect the immune system in pregnant women and/or fetuses, reflecting an acute and/or chronic effect, although unmeasured confounders could also play a role...
  6. pmc Blood mercury concentrations in CHARGE Study children with and without autism
    Irva Hertz-Picciotto
    Department of Public Health Sciences, University of California Davis, Davis, California 95616 8638, USA
    Environ Health Perspect 118:161-6. 2010
    ..Some authors have reported higher blood mercury (Hg) levels in persons with autism, relative to unaffected controls...
  7. ncbi request reprint In utero polychlorinated biphenyl exposures in relation to fetal and early childhood growth
    Irva Hertz-Picciotto
    Department of Epidemiology, School of Public Health, University of North Carolina Chapel Hill, Chapel Hill, NC, USA
    Epidemiology 16:648-56. 2005
    ..Studies examining intrauterine growth at lower exposures have been inconsistent, with most such investigations having relied on surrogate exposure indicators such as consumption of fish from contaminated bodies of water...
  8. ncbi request reprint The rise in autism and the role of age at diagnosis
    Irva Hertz-Picciotto
    Department of Public Health Sciences, University of California, Davis, California 95616, USA
    Epidemiology 20:84-90. 2009
    ..The extent to which this trend is explained by changes in age at diagnosis or inclusion of milder cases has not been previously evaluated...
  9. pmc A cohort study of in utero polychlorinated biphenyl (PCB) exposures in relation to secondary sex ratio
    Irva Hertz-Picciotto
    Department of Public Health Sciences, School of Medicine, TB 168, University of California Davis, Davis, CA 95616, USA
    Environ Health 7:37. 2008
    ..PCBs are related to a class of compounds known as dioxins, specifically 2,3,7,8-TCDD (tetrachloro-dibenzodioxin), which has been implicated as a cause of altered sex ratio, especially in relation to paternal exposures...
  10. pmc The CHARGE study: an epidemiologic investigation of genetic and environmental factors contributing to autism
    Irva Hertz-Picciotto
    Division of Epidemiology, Department of Public Health Sciences, School of Medicine, and Medical Investigations of Neurodevelopmental Disorders MIND Institute, University of California Davis, Davis, California, USA
    Environ Health Perspect 114:1119-25. 2006
    ....
  11. doi request reprint Prenatal exposures to persistent and non-persistent organic compounds and effects on immune system development
    Irva Hertz-Picciotto
    Center for Children s Environmental Health and Department of Public Health Sciences, University of California, Davis, CA 95616, USA
    Basic Clin Pharmacol Toxicol 102:146-54. 2008
    ....
  12. pmc Early childhood lower respiratory illness and air pollution
    Irva Hertz-Picciotto
    Department of Public Health Sciences, University of California, Davis, California 95616, USA
    Environ Health Perspect 115:1510-8. 2007
    ..Few studies of air pollutants address morbidity in preschool children. In this study we evaluated bronchitis in children from two Czech districts: Teplice, with high ambient air pollution, and Prachatice, characterized by lower exposures...
  13. pmc Study of Use of Products and Exposure-Related Behaviors (SUPERB): study design, methods, and demographic characteristics of cohorts
    Irva Hertz-Picciotto
    Department of Public Health Sciences, School of Medicine, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA
    Environ Health 9:54. 2010
    ....
  14. ncbi request reprint Is it time to abandon adjustment for birth weight in studies of infant mortality?
    Irva Hertz-Picciotto
    Department of Epidemiology and Preventive Medicine, University of California, Davis, CA 95616, USA
    Paediatr Perinat Epidemiol 17:114-6. 2003
  15. pmc Polybrominated diphenyl ethers in relation to autism and developmental delay: a case-control study
    Irva Hertz-Picciotto
    Department of Public Health Sciences, School of Medicine, University of California, MS1C, One Shields Ave, Davis, California, USA
    Environ Health 10:1. 2011
    ..PBDEs and their metabolites cross the placenta and studies in rodents demonstrate neurodevelopmental toxicity from prenatal exposures. PBDE exposures occur both via breastfeeding and hand-to-mouth activities in small children...
  16. ncbi request reprint Hot tubs and miscarriage--methodological and substantive reasons why the case is weak
    Irva Hertz-Picciotto
    Department of Epidemiology and Preventive Medicine, University of California, Davis, Davis, CA 95616, USA
    Am J Epidemiol 158:938-40; discussion 941. 2003
  17. doi request reprint Behavioral correlates of maternal antibody status among children with autism
    Daniel Braunschweig
    Division of Rheumatology Allergy and Clinical Immunology, University of California, Davis, 451 E Health Sciences Drive, Suite 6510 GBSF, Davis, CA 95616, USA
    J Autism Dev Disord 42:1435-45. 2012
    ..05). This study provides evidence of multiple patterns of reactivity to fetal brain proteins by maternal antibodies associated with ASD and specific childhood behavioral outcomes...
  18. pmc Polychlorinated biphenyls and their hydroxylated metabolites (OH-PCBS) in pregnant women from eastern Slovakia
    June Soo Park
    Department of Public Health Sciences, University of California Davis, Davis, California, USA
    Environ Health Perspect 115:20-7. 2007
    ..Our aim in the present study was to characterize and quantify the levels of polychlorinated biphenyls (PCBs) and specific polychlorobiphenylol (OH-PCB) metabolites in maternal sera from women delivering in eastern Slovakia...
  19. doi request reprint Prenatal polychlorinated biphenyl exposures in eastern Slovakia modify effects of social factors on birthweight
    Dean Sonneborn
    Division of Epidemiology, Department of Public Health Sciences, School of Medicine, University of California, Davis, CA 95616, USA
    Paediatr Perinat Epidemiol 22:202-13. 2008
    ....
  20. pmc Air pollution and lymphocyte phenotype proportions in cord blood
    Irva Hertz-Picciotto
    Department of Public Health Sciences, University of California, Davis, California, USA
    Environ Health Perspect 113:1391-8. 2005
    ..7% (95% CI, 0.4 to 3.0%). Associations were similar but slightly weaker for PM2.5. Ambient air pollution may influence the relative distribution of lymphocyte immunophenotypes of the fetus...
  21. pmc Neurodevelopmental toxicity of prenatal polychlorinated biphenyls (PCBs) by chemical structure and activity: a birth cohort study
    Hye Youn Park
    Divisions of Epidemiology, and of Environmental and Occupational Health, Department of Public Health Sciences, School of Medicine, University of California, Davis 95616, USA
    Environ Health 9:51. 2010
    ..Our objective was to examine the association between prenatal exposure to defined subsets of PCBs and neurodevelopment in a cohort of infants in eastern Slovakia enrolled at birth in 2002-2004...
  22. pmc Air pollution exposure during critical time periods in gestation and alterations in cord blood lymphocyte distribution: a cohort of livebirths
    Caroline E W Herr
    Department of Public Health Sciences, University of California, Davis, USA
    Environ Health 9:46. 2010
    ..This study investigates the association between cord blood lymphocyte proportions and maternal exposure to air pollution during each gestational month...
  23. doi request reprint Exposure to air pollution in critical prenatal time windows and IgE levels in newborns
    Caroline E W Herr
    Department of Public Health Sciences, Division of Epidemiology, University of California Davis, CA 95616, USA
    Pediatr Allergy Immunol 22:75-84. 2011
    ..PAHs and PM(2.5) , constituents of both ambient air pollution and cigarette smoke, appear to influence fetal immune development, particularly among infants whose mothers are not atopic...
  24. pmc Maternal periconceptional folic acid intake and risk of autism spectrum disorders and developmental delay in the CHARGE (CHildhood Autism Risks from Genetics and Environment) case-control study
    Rebecca J Schmidt
    Department of Public Health Sciences, University of California Davis School of Medicine, Davis, CA 95616 8638, USA
    Am J Clin Nutr 96:80-9. 2012
    ..Periconceptional folate is essential for proper neurodevelopment...
  25. ncbi request reprint Maternal DDT exposures in relation to fetal and 5-year growth
    Todd A Jusko
    Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA 98195, USA
    Epidemiology 17:692-700. 2006
    ..Furthermore, only a portion of these studies have investigated in utero exposures and growth during childhood...
  26. pmc Placental transfer of polychlorinated biphenyls, their hydroxylated metabolites and pentachlorophenol in pregnant women from eastern Slovakia
    June Soo Park
    Department of Public Health Sciences, University of California Davis, Davis, CA 95616, USA
    Chemosphere 70:1676-84. 2008
    ..These findings are consistent with their preferential binding to TTR that can cross the placenta. The cord to maternal ratio varies by congener (e.g., 4-OH-CB107=0.58, 4-OH-CB146=0.74, 3'-OH-CB138=1.01)...
  27. pmc Autism: maternally derived antibodies specific for fetal brain proteins
    Daniel Braunschweig
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, CA, USA
    Neurotoxicology 29:226-31. 2008
    ....
  28. doi request reprint Ambient nitrogen oxides exposure and early childhood respiratory illnesses
    Rakesh Ghosh
    Department of Public Health Sciences, University of California, Davis, Davis, CA 95616, USA
    Environ Int 39:96-102. 2012
    ..The evidence, if causal, can be of public health concern because acute respiratory illnesses are common in preschool children...
  29. pmc Longitudinal variability of time-location/activity patterns of population at different ages: a longitudinal study in California
    Xiangmei Wu
    Department of Public Health Sciences, University of California, Davis, CA, USA
    Environ Health 10:80. 2011
    ..This study was designed to evaluate longitudinal variations in human time-activity patterns...
  30. doi request reprint Indoor coal use and early childhood growth
    Rakesh Ghosh
    Department of Public Health Sciences, University of California, Davis, Davis, CA 95616, USA
    Arch Pediatr Adolesc Med 165:492-7. 2011
    ..To examine whether indoor coal combustion for heating, which releases pollutants into the air, affects early childhood growth...
  31. ncbi request reprint Geographic distribution of autism in California: a retrospective birth cohort analysis
    Karla C Van Meter
    Department of Public Health Sciences, School of Medicine, and Medical Investigations of Neurodevelopmental Disorders Institute, University of California Davis, One Shields Avenue, Davis, CA 95616, USA
    Autism Res 3:19-29. 2010
    ..nonhigh-school graduate parents. This geographic association possibly occurs because RCs do not actively conduct case finding and parents with lower education are, for various reasons, less likely to successfully seek services...
  32. doi request reprint Serum PCB concentrations in relation to locally produced food items in eastern Slovakia
    Dean Sonneborn
    Division of Epidemiology, Department of Public Health Sciences, School of Medicine, University of California, Davis, California 95616 8638, USA
    J Expo Sci Environ Epidemiol 18:581-7. 2008
    ..8% 630 ng/g lipid versus 549 ng/g lipid...
  33. doi request reprint Air pollutants, genes and early childhood acute bronchitis
    Rakesh Ghosh
    Department of Public Health Sciences, University of California, Davis, USA Electronic address
    Mutat Res 749:80-6. 2013
    ..5μm (PM2.5)) with acute bronchitis in children below two years...
  34. pmc Temporal variation of residential pesticide use and comparison of two survey platforms: a longitudinal study among households with young children in Northern California
    Xiangmei May Wu
    Department of Public Health Sciences, University of California, Davis, CA, USA
    Environ Health 12:65. 2013
    ....
  35. pmc Is maternal influenza or fever during pregnancy associated with autism or developmental delays? Results from the CHARGE (CHildhood Autism Risks from Genetics and Environment) study
    Ousseny Zerbo
    Department of Public Health Sciences, MS1C, University of California Davis, CA 95616, USA
    J Autism Dev Disord 43:25-33. 2013
    ..However, the fever-associated ASD risk was attenuated among mothers who reported taking antipyretic medications (OR = 1.30, 95 % CI 0.59, 2.84), but remained elevated for those who did not (OR = 2.55, 95 % CI 1.30, 4.99)...
  36. doi request reprint Passive sampling methods to determine household and personal care product use
    Deborah H Bennett
    Department of Public Health Sciences, University of California, Davis, California, USA
    J Expo Sci Environ Epidemiol 22:148-60. 2012
    ..A very low drop-out rate suggests that this methodology can be useful in longitudinal studies of exposure to household and personal care products...
  37. doi request reprint Residential insecticide usage in northern California homes with young children
    Xiangmei May Wu
    Department of Public Health Sciences, University of California, Davis, CA 95616, USA
    J Expo Sci Environ Epidemiol 21:427-36. 2011
    ..These findings describing the intensity of insecticide use and accompanying behaviors in families with young children may inform future insecticide exposure modeling efforts, and ultimately, risk assessments...
  38. doi request reprint Feasibility of using web surveys to collect time-activity data
    Xiangmei May Wu
    Department of Public Health Sciences, University of California, Davis, California, USA
    J Expo Sci Environ Epidemiol 22:116-25. 2012
    ..In conclusion, web surveys are a promising method to consider for time-activity data collection...
  39. pmc Trophoblast inclusions are significantly increased in the placentas of children in families at risk for autism
    Cheryl K Walker
    Department of Obstetrics and Gynecology, School of Medicine, University of California, Davis, Davis, California, USA
    Biol Psychiatry 74:204-11. 2013
    ..This study examined whether the presence of trophoblast inclusions (TIs) in the placenta could serve as a predictor for children at elevated risk for autism spectrum disorder (ASD)...
  40. pmc Cancer and non-cancer health effects from food contaminant exposures for children and adults in California: a risk assessment
    Rainbow Vogt
    UC Davis, Department of Public Health Sciences, 1 Shields Avenue, Davis, CA 95616, USA
    Environ Health 11:83. 2012
    ..In the absence of current cumulative dietary exposure assessments, this analysis was conducted to estimate exposure to multiple dietary contaminants for children, who are more vulnerable to toxic exposure than adults...
  41. pmc Autoantibodies to cerebellum in children with autism associate with behavior
    Paula Goines
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, Davis, CA 95616, United States
    Brain Behav Immun 25:514-23. 2011
    ..Future studies are needed to determine the identities of the protein targets and explore their significance in autism...
  42. ncbi request reprint Sleep problems in children with autism spectrum disorders, developmental delays, and typical development: a population-based study
    Paula Krakowiak
    Division of Epidemiology, Department of Public Health Sciences, School of Medicine, University of California, Davis, CA, USA
    J Sleep Res 17:197-206. 2008
    ..Factor scores for children with DD were intermediate between the ASD and TD groups. Cognitive or adaptive development did not predict severity of sleep problems in the ASD group...
  43. pmc MAOA, DBH, and SLC6A4 variants in CHARGE: a case-control study of autism spectrum disorders
    Flora Tassone
    Department of Biochemistry and Molecular Medicine, School of Medicine, University of California, Davis, California 95616, USA
    Autism Res 4:250-61. 2011
    ..19, 7.91, P = 0.02 for AU vs. TD, and OR = 3.26, 95% CI = 1.35, 7.89, P = 0.009 for AU+ASD vs. TD). These results suggest a potential role of the functional MAOA promoter alleles in the male child, the mother, or both in ASD...
  44. pmc Month of conception and risk of autism
    Ousseny Zerbo
    Department of Public Health Sciences, School of Medicine, University of California, Davis, CA 95616, USA
    Epidemiology 22:469-75. 2011
    ..We investigated whether certain months or seasons of conception are associated with increased risk of autism spectrum disorders, for which etiology is particularly obscure...
  45. pmc Determinants of serum polychlorinated biphenyls and organochlorine pesticides measured in women from the child health and development study cohort, 1963-1967
    Rebecca A James
    Department of Epidemiology, School of Public Health, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, USA
    Environ Health Perspect 110:617-24. 2002
    ..Marked racial and regional differences in serum pesticide levels were likely caused by geographic variation in previous agricultural and vector-control uses. The relationship to body mass index appears to be complex...
  46. ncbi request reprint Calcium intake during pregnancy among white and African-American pregnant women in the United States
    Emily W Harville
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 7435, USA
    J Am Coll Nutr 23:43-50. 2004
    ..To characterize the calcium intake in a racially mixed cohort of pregnant women, including the contribution of supplementation and antacids...
  47. ncbi request reprint Brief report: plasma leptin levels are elevated in autism: association with early onset phenotype?
    Paul Ashwood
    Department of Medical Microbiology and Immunology, University of California at Davis, Davis, CA 95616, USA
    J Autism Dev Disord 38:169-75. 2008
    ..042), TD controls (p<.0015), and DD controls (p<.004). We demonstrated an increase in leptin levels in autism, a finding driven by the early onset group...
  48. ncbi request reprint PBDEs in 2-5 year-old children from California and associations with diet and indoor environment
    Melissa Rose
    Department of Public Health Sciences, University of California, Davis, California 95616, USA
    Environ Sci Technol 44:2648-53. 2010
    ..Concentrations of lower-brominated congeners increased with frequency of poultry consumption. Lower maternal education was independently and significantly associated with higher levels of most congeners in the children...
  49. pmc Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome
    Paul Ashwood
    Department of Medical Microbiology and Immunology, University of California, Davis, CA, USA
    Brain Behav Immun 25:40-5. 2011
    ..The characterization of immunological parameters in ASD has important implications for diagnosis, and should be considered when designing therapeutic strategies to treat core symptoms and behavioral impairments of ASD...
  50. pmc Altered T cell responses in children with autism
    Paul Ashwood
    Department of Medical Microbiology and Immunology, University of California at Davis, CA, USA
    Brain Behav Immun 25:840-9. 2011
    ..Further longitudinal analyzes of cellular immunity profiles would delineate the relationship between immune dysfunction and the progression of behavioral and developmental changes throughout the course of this disorder...
  51. pmc Maternal metabolic conditions and risk for autism and other neurodevelopmental disorders
    Paula Krakowiak
    Division of Epidemiology, Department of Public Health Sciences, University of California, Davis, California, USA
    Pediatrics 129:e1121-8. 2012
    ....
  52. doi request reprint Usage pattern of personal care products in California households
    Xiangmei May Wu
    Department of Public Health Sciences, University of California, Davis, CA 95616, USA
    Food Chem Toxicol 48:3109-19. 2010
    ..This information will be valuable for exposure and risk assessments...
  53. pmc Psychosocial factors and preterm birth among African American and White women in central North Carolina
    Nancy Dole
    Carolina Population Center, CB 8120, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 8120, USA
    Am J Public Health 94:1358-65. 2004
    ..We assessed associations between psychosocial factors and preterm birth, stratified by race in a prospective cohort study...
  54. pmc Residential pesticide usage in older adults residing in Central California
    Mary N Armes
    Department of Epidemiology, School of Public Health, University of California, Los Angeles, Los Angeles, CA 90095, USA
    Int J Environ Res Public Health 8:3114-33. 2011
    ..Our findings on frequency of use over lifetime and exposure related behaviors will inform future efforts to develop population pesticide exposure models and risk assessment...
  55. pmc Prenatal vitamins, one-carbon metabolism gene variants, and risk for autism
    Rebecca J Schmidt
    Department of Public Health Sciences, University of California Davis School of Medicine, Davis, CA, USA
    Epidemiology 22:476-85. 2011
    ..Causes of autism are unknown. Associations with maternal nutritional factors and their interactions with gene variants have not been reported...
  56. pmc Reduced levels of immunoglobulin in children with autism correlates with behavioral symptoms
    Luke Heuer
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, Davis, California 95616, USA
    Autism Res 1:275-83. 2008
    ..To assay if plasma antibody levels in children with autism or developmental delays (DD) differ from those with typical development as an indicator of immune function and to correlate antibody levels with severity of behavioral symptoms...
  57. ncbi request reprint Conditions for bias from differential left truncation
    Penelope P Howards
    Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, Rockville, MD 20852, USA
    Am J Epidemiol 165:444-52. 2007
    ..Cox regression can correct for left truncation and is no more difficult to perform than logistic regression...
  58. pmc Social correlates of the chronic stress of perceived racism among Black women
    Anissa I Vines
    Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, USA
    Ethn Dis 16:101-7. 2006
    ..This study describes the perceptions of racism, passive and active responses to this psychosocial stressor, and it examines socioeconomic correlates of perceived racism in an economically diverse population of Black women...
  59. ncbi request reprint Comparison of organochlorine compound concentrations in colostrum and mature milk
    Zhiwei Yu
    University of California, Davis, Department of Public Health Sciences, Davis, CA 95616, USA
    Chemosphere 66:1012-8. 2007
    ....
  60. ncbi request reprint Self-reported heavy bleeding associated with uterine leiomyomata
    Ganesa Wegienka
    Department of Epidemiology, University of North Carolina School of Public Health, Chapel Hill, North Carolina, USA
    Obstet Gynecol 101:431-7. 2003
    ..To characterize the relationship between self-reported bleeding symptoms and uterine leiomyoma size and location...
  61. doi request reprint Identification of expanded alleles of the FMR1 Gene in the CHildhood Autism Risks from Genes and Environment (CHARGE) study
    Flora Tassone
    Department of Biochemistry and Molecular Medicine, School of Medicine, University of California, Davis, 2700 Stockton Blvd, Suite 2102, Sacramento, CA 95817, USA
    J Autism Dev Disord 43:530-9. 2013
    ..We have identified six subjects carrying an expanded allele, which emphasize the importance of screening for FXS in a population with intellectual disabilities and ASD...
  62. ncbi request reprint Misclassification of gestational age in the study of spontaneous abortion
    Penelope P Howards
    Division of Epidemiology, Statistics, and Prevention Research, National Institute of Child Health and Human Development, Bethesda, MD, USA
    Am J Epidemiol 164:1126-36. 2006
    ..Bias was greatest when the magnitude of error for pregnancies at higher risk was much larger than that for pregnancies at lower risk...
  63. doi request reprint Regression in autism: prevalence and associated factors in the CHARGE Study
    Robin L Hansen
    Medical Investigation of Neurodevelopmental Disorders Institute, University of California, Davis, Sacramento 95817, USA
    Ambul Pediatr 8:25-31. 2008
    ..The aim of this study was to examine the prevalence of regressive autism and associated demographic, medical, and developmental factors by using 2 different definitions of regression based on the Autism Diagnostic Interview, Revised...
  64. doi request reprint Independent and dependent contributions of advanced maternal and paternal ages to autism risk
    Janie F Shelton
    Department of Public Health Sciences, University of California Davis, Davis, CA 95616, USA
    Autism Res 3:30-9. 2010
    ..We also calculated that the recent trend towards delayed childbearing contributed approximately a 4.6% increase in autism diagnoses in California over the decade...
  65. ncbi request reprint Gene expression changes in children with autism
    Jeffrey P Gregg
    Department of Pathology, University of California at Davis Medical Center, Sacramento, CA 95817, USA University of California at Davis, Davis, CA 95616, USA
    Genomics 91:22-9. 2008
    ..05). We conclude that the gene expression data support emerging evidence for abnormalities in peripheral blood leukocytes in autism that could represent a genetic and/or environmental predisposition to the disorder...
  66. pmc Tipping the balance of autism risk: potential mechanisms linking pesticides and autism
    Janie F Shelton
    Graduate Group in Epidemiology, Department of Public Health Science, University of California, Davis, Davis, California 95616, USA
    Environ Health Perspect 120:944-51. 2012
    ..Because multiple developmental processes are implicated in ASDs during gestation and early life, biological plausibility is more likely if these agents can be shown to affect core pathophysiological features...
  67. doi request reprint Autism spectrum disorders in Hispanics and non-Hispanics
    Virginia Chaidez
    Department of Public Health Sciences, University of California, Davis, CA 95618, USA
    Autism 16:381-97. 2012
    ..To compare differences in autism between Hispanic and non-Hispanics. We also examined the relationship between multiple language exposure and language function and scores of children...
  68. doi request reprint Minor physical anomalies in children with autism spectrum disorders
    Kathleen Angkustsiri
    University of California, Davis, USA
    Autism 15:746-60. 2011
    ..This study employs an adaptation of Miles and Hillman's (2000) classifications by using photographs to identify a subgroup with significant dysmorphology among children with ASD, typical development (TYP), and developmental delay (DD)...
  69. ncbi request reprint Invited commentary: disinfection by-products and pregnancy loss--lessons
    Penelope P Howards
    Division of Epidemiology, Statistics, and Prevention Research, National Institute of Child Health and Human Development, Bethesda, MD, USA
    Am J Epidemiol 164:1052-5. 2006
  70. ncbi request reprint Mitochondrial dysfunction in autism
    Cecilia Giulivi
    University of California, School of Veterinary Medicine, Department of Molecular Biosciences, One Shields Avenue, 1120 Haring Hall, Davis, CA 95616, USA
    JAMA 304:2389-96. 2010
    ..No studies have evaluated mitochondrial dysfunction and mitochondrial DNA (mtDNA) abnormalities in a well-defined population of children with autism...
  71. ncbi request reprint Choice of exposure scores for categorical regression in meta-analysis: a case study of a common problem
    Dora Il'yasova
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
    Cancer Causes Control 16:383-8. 2005
    ..This method requires the assignment of a single score to each exposure category. We examined how closely meta-analytical categorical regression approximates the results of analysis based on the individual-level continuous exposure...
  72. pmc Decreased transforming growth factor beta1 in autism: a potential link between immune dysregulation and impairment in clinical behavioral outcomes
    Paul Ashwood
    Department of Medical Microbiology and Immunology, University of California at Davis, United States
    J Neuroimmunol 204:149-53. 2008
    ..Such immune dysregulation may predispose to the development of possible autoimmune responses and/or adverse neuroimmune interactions during critical windows in development...
  73. pmc Associations of impaired behaviors with elevated plasma chemokines in autism spectrum disorders
    Paul Ashwood
    Department of Medical Microbiology and Immunology, and The M I N D Institute, University of California at Davis, CA, United States
    J Neuroimmunol 232:196-9. 2011
    ..Elevated MCP-1, RANTES and eotaxin in some ASD children and their association with more impaired behaviors may have etiological significance. Chemokines and their receptors might provide unique targets for future therapies in ASD...
  74. pmc Decreased cellular IL-23 but not IL-17 production in children with autism spectrum disorders
    Charity Onore
    Department of Medical Microbiology and Immunology, University of California at Davis, USA
    J Neuroimmunol 216:126-9. 2009
    ..Decreased cellular IL-23 production in ASD warrants further research to determine its role on the generation and survival of T(H)17 cells, a cell subset important in neuroinflammatory conditions that may include ASD...
  75. pmc Correlations of gene expression with blood lead levels in children with autism compared to typically developing controls
    Yingfang Tian
    Department of Neurology, University of California at Davis, Sacramento, CA 95817, USA
    Neurotox Res 19:1-13. 2011
    ..We postulate that this may relate to the underlying genetic differences between the two groups, though other explanations cannot be excluded...
  76. pmc Correlations between gene expression and mercury levels in blood of boys with and without autism
    Boryana Stamova
    Department of Neurology, University of California at Davis Medical Center, Sacramento, CA 95817, USA
    Neurotox Res 19:31-48. 2011
    ..These findings might suggest different genetic transcriptional programs associated with mercury in AU compared to TD children...
  77. ncbi request reprint Have studies of urinary tract infection and preterm delivery used the most appropriate methods?
    Marie S O'Neill
    Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, NC, USA
    Paediatr Perinat Epidemiol 17:226-33. 2003
    ..Data on UTI timing should be gathered to allow appropriate analyses; survival methods account for person-time under observation and ensure that studied exposures precede effects...
  78. pmc A procedure to characterize geographic distributions of rare disorders in cohorts
    Karla C Van Meter
    Department of Public Health Sciences, School of Medicine, University of California, Davis, USA
    Int J Health Geogr 7:26. 2008
    ..Using simulations, this study explored the effects of low cluster RR and areal unit size on local area clustering test (LACT) results, proposing a procedure to improve accuracy of cohort spatial analysis for rare events...
  79. ncbi request reprint Adult hemoglobin levels at birth and risk of sudden infant death syndrome
    David B Richardson
    Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 8050, USA
    Arch Pediatr Adolesc Med 158:366-71. 2004
    ..Delayed or faulty transition to the production of adult hemoglobin might play a role in the etiology of sudden infant death syndrome (SIDS)...
  80. pmc MECP2 promoter methylation and X chromosome inactivation in autism
    Raman P Nagarajan
    Medical Microbiology and Immunology and Rowe Program in Human Genetics, University of California, Davis, CA 95616, USA
    Autism Res 1:169-78. 2008
    ..These results suggest that the aberrant MECP2 methylation in autism brain DNA samples is due to locus-specific rather than global X chromosome methylation changes...
  81. pmc The onset of autism: patterns of symptom emergence in the first years of life
    Sally Ozonoff
    M I N D Institute, University of California Davis, Sacramento, USA
    Autism Res 1:320-8. 2008
    ..We suggest that onset is better thought of as a dimensional process rather than dichotomous categories...
  82. pmc Associations of abdominal fat with perceived racism and passive emotional responses to racism in African American women
    Anissa I Vines
    Department of Epidemiology, University of North Carolina, Chapel Hill, Chapel Hill, NC 27516, USA
    Am J Public Health 97:526-30. 2007
    ..Passive emotional responses to perceived racism, hypothesized to have particularly adverse effects, were also examined...
  83. pmc Child care and social support modify the association between maternal depressive symptoms and early childhood behaviour problems: a US national study
    Li Ching Lee
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe Street, Room E6032, Baltimore, MD 21205, USA
    J Epidemiol Community Health 60:305-10. 2006
    ..To investigate the presence and patterns of modification effects of the sex of the child, social support, and childcare on the relation between maternal depressive symptoms and child behaviour problems at two developmental stages...
  84. ncbi request reprint Epidemiologic measures of the course and outcome of pregnancy
    David A Savitz
    Department of Epidemiology, University of North Carolina School of Public Health, Chapel Hill, NC, USA
    Epidemiol Rev 24:91-101. 2002
  85. ncbi request reprint Bed rest and other determinants of bone loss during pregnancy
    Joanne H E Promislow
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
    Am J Obstet Gynecol 191:1077-83. 2004
    ..The purpose of this study was to evaluate patterns of bone loss during pregnancy and potential influences...
  86. ncbi request reprint Self-collected breath sampling for monitoring low-level benzene exposures among automobile mechanics
    Peter P Egeghy
    Department of Environmental Sciences and Engineering, School of Public Health, University of North Carolina at Chapel Hill, 27599 7400, USA
    Ann Occup Hyg 46:489-500. 2002
    ....
  87. ncbi request reprint Arsenic exposure from drinking water and birth weight
    Claudia Hopenhayn
    School of Public Health and Markey Cancer Center, University of Kentucky, Lexington, KY 40504, USA
    Epidemiology 14:593-602. 2003
    ..Limited evidence suggests that arsenic may have adverse human reproductive effects. We investigated the association between drinking water arsenic exposure and fetal growth, as manifest in birth weight...
  88. doi request reprint The faroes statement: human health effects of developmental exposure to chemicals in our environment
    Philippe Grandjean
    Basic Clin Pharmacol Toxicol 102:73-5. 2008
  89. ncbi request reprint Maternal amalgam dental fillings as the source of mercury exposure in developing fetus and newborn
    Lubica Palkovicova
    Department of Environmental Medicine, Slovak Medical University, Bratislava, Slovakia
    J Expo Sci Environ Epidemiol 18:326-31. 2008
    ..37, P<0.001); these associations remained significant after adjustment for maternal age and education. Dental amalgam fillings in girls and women of reproductive age should be used with caution, to avoid increased prenatal Hg exposure...
  90. ncbi request reprint Association between arsenic exposure from drinking water and anemia during pregnancy
    Claudia Hopenhayn
    College of Public Health, University of Kentucky, Lexington, Kentucky 40504, USA
    J Occup Environ Med 48:635-43. 2006
    ..Arsenic is associated with numerous health effects. We investigated the association between arsenic exposure from drinking water and anemia during pregnancy...
  91. pmc Maternal and cord serum exposure to PCB and DDE methyl sulfone metabolites in eastern Slovakia
    Linda Linderholm
    Department of Environmental Chemistry, Stockholm University, SE 106 91 Stockholm, Sweden
    Chemosphere 69:403-10. 2007
    ..The difference in the maternal:cord ratio, comparing MeSO(2)-PCBs with 3-MeSO(2)-DDE might be due to differences in transport through the placenta caused by their different affinities for lipoproteins and plasma proteins...
  92. pmc Comparison of polychlorinated biphenyl levels across studies of human neurodevelopment
    Matthew P Longnecker
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 111:65-70. 2003
    ..S. studies or recent Dutch, German, and northern Québec studies. Our results will facilitate a direct comparison of the findings on PCBs and neurodevelopment when they are published for all 10 studies...
  93. ncbi request reprint Uterine leiomyomata (fibroids): are bleeding symptoms more likely to be reported after diagnosis?
    Ganesa Wegienka
    J Clin Epidemiol 57:318-20. 2004
  94. ncbi request reprint A simple approach to performing quantitative cancer risk assessment using published results from occupational epidemiology studies
    Edwin van Wijngaarden
    Health Sciences Institute, ENVIRON International Corporation, PO Box 2424, Amherst, MA 01004, USA
    Sci Total Environ 332:81-7. 2004
    ..The methods described should facilitate the use of published epidemiological data in the estimation of cancer risk in the general or working population...
  95. ncbi request reprint The DNA repair gene XPD/ERCC2 polymorphisms Arg156Arg (exon 6) and Lys751Gln (exon 23) are closely associated
    Jan Topinka
    Laboratory of Genetic Ecotoxicology, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic
    Toxicol Lett 172:85-9. 2007
    ....
  96. ncbi request reprint Sostrup statement on low birthweight
    Melissa Adams
    Int J Epidemiol 32:884-5. 2003
  97. ncbi request reprint Do associations between airborne particles and daily mortality in Mexico City differ by measurement method, region, or modeling strategy?
    Marie S O'Neill
    University of North Carolina UNC at Chapel Hill, USA
    J Expo Anal Environ Epidemiol 14:429-39. 2004
    ..The reanalysis suggests that previous research is robust to statistical method and likely to yield the same overall conclusions about the short-term effects of airborne particles on mortality...
  98. ncbi request reprint Attenuation of exposure-response curves in occupational cohort studies at high exposure levels
    Leslie Stayner
    Risk Evaluation Branch, Education and Information Division, National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, United States
    Scand J Work Environ Health 29:317-24. 2003
    ....

Research Grants13

  1. The Charge Study: Childhood Autism Risks from Genetics and the Environment
    Irva Hertz Picciotto; Fiscal Year: 2010
    ..This project addresses a critical and growing public health concern, namely, autism;this disorder affects as many as one in 166 children. Our project will evaluate risk factors that may play a causal role. ..
  2. The Charge Study: Childhood Autism Risks from Genetics and the Environment
    Irva Hertz Picciotto; Fiscal Year: 2009
    ..This project addresses a critical and growing public health concern, namely, autism; this disorder affects as many as one in 166 children. Our project will evaluate risk factors that may play a causal role. ..
  3. Early Childhood Development and PCB Exposures in Slovak*
    Irva Hertz Picciotto; Fiscal Year: 2002
    ..Other unique features include the evaluation of hearing loss at birth, the measurement of hydroxy and methylsulfone metabolites of PCBs, and a population which includes about 1/3 Gypsies. ..
  4. Early Childhood Development and PCB Exposures in Slovak*
    Irva Hertz Picciotto; Fiscal Year: 2003
    ..Other unique features include the evaluation of hearing loss at birth, the measurement of hydroxy and methylsulfone metabolites of PCBs, and a population which includes about 1/3 Gypsies. ..
  5. Early Childhood Development and PCB Exposures in Slovak*
    Irva Hertz Picciotto; Fiscal Year: 2004
    ..Other unique features include the evaluation of hearing loss at birth, the measurement of hydroxy and methylsulfone metabolites of PCBs, and a population which includes about 1/3 Gypsies. ..
  6. The Charge Study: Childhood Autism Risks from Genetics and the Environment
    Irva Hertz Picciotto; Fiscal Year: 2009
    ..This supplement will also address a major goal of the American Recovery and Reinvestment Act by the creation of 3.5 new jobs. ..
  7. The Charge Study: Childhood Autism Risks from Genetics and the Environment
    Irva Hertz Picciotto; Fiscal Year: 2009
    ..This project addresses a critical and growing public health concern, namely, autism; this disorder affects as many as one in 166 children. Our project will evaluate risk factors that may play a causal role. ..
  8. The Charge Study: Childhood Autism Risks from Genetics and the Environment
    Irva Hertz Picciotto; Fiscal Year: 2007
    ..This project addresses a critical and growing public health concern, namely, autism; this disorder affects as many as one in 166 children. Our project will evaluate risk factors that may play a causal role. ..
  9. Early Childhood Development and PCB Exposures in Slovak*
    Irva Hertz Picciotto; Fiscal Year: 2005
    ..Other unique features include the evaluation of hearing loss at birth, the measurement of hydroxy and methylsulfone metabolites of PCBs, and a population which includes about 1/3 Gypsies. ..
  10. International Society Environmental Epidemiology 2003
    Irva Hertz Picciotto; Fiscal Year: 2003
    ..ISEE provides a variety of forums for discussion, critical reviews, collaborations and education issues for environmental exposures and their human health effects. ..
  11. Early Childhood Development and PCB Exposures
    Irva Hertz Picciotto; Fiscal Year: 2001
    ..Other unique features include the evaluation of hearing loss at birth, the measurement of hydroxy and methylsulfone metabolites of PCBs, and a population which includes about 1/3 Gypsies. ..