Research Topics
Species | BRUCE PHILLIP HERMANNSummaryAffiliation: University of Wisconsin Country: USA Publications
Research Grants
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Detail Information
Publications
Starting at the beginning: the neuropsychological status of children with new-onset epilepsiesBruce P Hermann
Department of Neurology, University of Wisconsin School of Medicine, Public Health, Madison WI 5307056, USA
Epileptic Disord 14:12-21. 2012..This becomes the substrate upon which to characterise the effects of epilepsy and its treatment on subsequent neurodevelopment. The review concludes with suggestions for future clinical care and research...
Reduced hippocampal activation during episodic encoding in middle-aged individuals at genetic risk of Alzheimer's disease: a cross-sectional studyMehul A Trivedi
Geriatric Research Education and Clinical Center, William S Middleton Veteran s Affairs Hospital, Madison, WI, USA
BMC Med 4:1. 2006....- Brain development in children with new onset epilepsy: a prospective controlled cohort investigationBruce P Hermann
Department of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
Epilepsia 51:2038-46. 2010..To characterize prospective neurodevelopmental changes in brain structure in children with new and recent-onset epilepsy compared to healthy controls... 
Cerebellar atrophy in temporal lobe epilepsyBruce P Hermann
Department of Neurology, University of Wisconsin, Madison, WI 53792, USA
Epilepsy Behav 7:279-87. 2005..The goal of this work was to determine the presence and degree of cerebellar atrophy in chronic temporal lobe epilepsy, its clinical seizure correlates, and its association with general cortical atrophy...- Growing up with epilepsy: a two-year investigation of cognitive development in children with new onset epilepsyBruce P Hermann
Department of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA
Epilepsia 49:1847-58. 2008..To characterize patterns and determinants of normal and abnormal cognitive development in children with new onset epilepsy compared to healthy controls... - Cognitive prognosis in chronic temporal lobe epilepsyBruce P Hermann
Matthews Neuropsychology Lab, Department of Neurology, University of Wisconsin Madison, 53792, USA
Ann Neurol 60:80-7. 2006.... - Children with new-onset epilepsy: neuropsychological status and brain structureBruce Hermann
Department of Neurology, University of Wisconsin Madison, WI 53792, USA
Brain 129:2609-19. 2006..These early abnormalities need to be integrated into lifespan models of the neuropsychology of epilepsy... - Cognitive phenotypes in temporal lobe epilepsyBruce Hermann
Department of Neurology, University of Wisconsin Madison, Madison, Wisconsin 53792, USA
J Int Neuropsychol Soc 13:12-20. 2007..The specific profile characteristics of the identified cognitive phenotypes are presented and their implications for the investigation of the neurobehavioral complications of epilepsy are discussed... - The frequency, complications and aetiology of ADHD in new onset paediatric epilepsyBruce Hermann
Matthews Neuropsychology Lab, Department of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
Brain 130:3135-48. 2007.... - Growing old with epilepsy: the neglected issue of cognitive and brain health in aging and elder persons with chronic epilepsyBruce Hermann
Department of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
Epilepsia 49:731-40. 2008..We suggest that a research agenda be developed to systematically identify and treat known modifiable risk factors in order to protect and promote cognitive and brain health in aging and elder persons with chronic epilepsy... - Cognitive and magnetic resonance volumetric abnormalities in new-onset pediatric epilepsyBruce P Hermann
Department of Neurology, University of Wisconsin School of Medicine and Public Health, Madison 53792, USA
Semin Pediatr Neurol 14:173-80. 2007..Subsets of children can be identified with salient academic and volumetric abnormalities. These findings represent the baseline upon which any subsequent effects of chronic epilepsy may accrue... - The neurobehavioural comorbidities of epilepsy: can a natural history be developed?Bruce Hermann
Department of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
Lancet Neurol 7:151-60. 2008..This Review summarises, from a lifespan perspective, the evidence for the neurodevelopmental origins of these comorbidities, how they develop over time, and their endpoints, with an emphasis on future clinical and research challenges... - The psychosocial impact of epilepsy in adultsBruce Hermann
Department of Neurology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI 53792, USA
Epilepsy Behav 15:S11-6. 2009.... - The emerging architecture of neuropsychological impairment in epilepsyBruce P Hermann
Department of Neurology, University of Wisconsin School of Medicine and Public Health, 600 North Highland Avenue, Madison, WI 53792, USA
Neurol Clin 27:881-907. 2009.... - 100 years of Epilepsia: landmark papers and their influence in neuropsychology and neuropsychiatryBruce Hermann
Department of Neurology, Matthews Neuropsychology Lab, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
Epilepsia 51:1107-19. 2010..These two papers are reviewed in detail and placed in historical context... - Cerebellar atrophy in temporal lobe epilepsy affects procedural memoryB Hermann
Matthews Neuropsychology Lab, Department of Neurology, University of Wisconsin, 600 N Highland, Madison, WI 53792, USA
Neurology 63:2129-31. 2004..These findings provide support for the hypothesis that cerebellar atrophy in epilepsy affects procedural memory... - Extratemporal quantitative MR volumetrics and neuropsychological status in temporal lobe epilepsyBruce Hermann
Department of Neurology, University of Wisconsin, Madison 53792, USA
J Int Neuropsychol Soc 9:353-62. 2003..g., duration and severity of epilepsy), remain to be determined... - Neurodevelopmental vulnerability of the corpus callosum to childhood onset localization-related epilepsyBruce Hermann
Department of Neurology, University of Wisconsin, Madison, WI 53792, USA
Neuroimage 18:284-92. 2003..These findings indicate that childhood onset of temporal lobe epilepsy is associated with an adverse neurodevelopmental impact on brain connectivity which is of clinical consequence and theoretical interest... - Classics in epilepsy and behavior: commentaryBruce Hermann
Department of Neurology, University of Wisconsin Medical School, 600 Highland Avenue, Madison, WI 53792, USA
Epilepsy Behav 4:365. 2003 - The neurodevelopmental impact of childhood-onset temporal lobe epilepsy on brain structure and functionBruce Hermann
Departments of Neurology and Radiology, University of Wisconsin, Madison, Wisconsin 53792, USA
Epilepsia 43:1062-71. 2002..To characterize the neurodevelopmental correlates of childhood-onset temporal lobe epilepsy on brain structure and cognition compared with late-onset chronic temporal lobe epilepsy and healthy controls... - The neurodevelopmental impact of childhood onset temporal lobe epilepsy on brain structure and function and the risk of progressive cognitive effectsBruce P Hermann
Department of Neurology, University of Wisconsin, 600 N Highland Ave, Madison, WI 53792, USA
Prog Brain Res 135:429-38. 2002.... - Psychiatric comorbidity in chronic epilepsy: identification, consequences, and treatment of major depressionB P Hermann
Department of Neurology, University of Wisconsin, Madison 53792, USA
Epilepsia 41:S31-41. 2000.... - Visual confrontation naming following left anterior temporal lobectomy: a comparison of surgical approachesB P Hermann
Department of Neurology, University of Wisconsin Madison, 53792 5132, USA
Neuropsychology 13:3-9. 1999..Across surgical approaches, the risk for decline in visual confrontation naming was associated with a later age of seizure onset and more extensive resection of lateral temporal neocortex... - Quantitative measurement of cortical surface features in localization-related temporal lobe epilepsyTemitayo Oyegbile
Department of Neurology, University of Wisconsin, Madison, WI 53792, USA
Neuropsychology 18:729-37. 2004..g., surface cerebral spinal fluid). These findings are related to the literature regarding morphometric changes associated with temporal lobe epilepsy and normal aging... - Memory relationships between MRI volumes and resting PET metabolism of medial temporal lobe structuresH Randall Griffith
Department of Neurology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
Epilepsy Behav 5:669-76. 2004..Multiple regression revealed that hippocampal volumes, but not PHG volumes or PET, significantly predicted PA and LM retention scores. These findings suggest that hippocampal volumes provide unique information regarding memory... - Rapid detection of major depression in epilepsy: a multicentre studyFrank G Gilliam
Department of Neurology, The Neurological Institute, Columbia University, New York, USA
Lancet Neurol 5:399-405. 2006..Depression is a common comorbid disorder in epilepsy but is not routinely assessed in neurology clinics. We aimed to create a rapid yet accurate screening instrument for major depression in people with epilepsy... - Quantitative MRI biomarkers of cognitive morbidity in temporal lobe epilepsyTayo O Oyegbile
Department of Neurology, University of Wisconsin-Madison, Madison, Wisconsin 53792, USA
Epilepsia 47:143-52. 2006..These biomarkers appear to mediate the adverse effects of some clinical seizure variables on cognition... - Protracted ictal confusion in elderly patientsRaj D Sheth
Department of Neurology, University of Wisconsin Madison, 600 Highland Avenue, Box H6 574 CSC, Madison, WI 53792 5132, USA
Arch Neurol 63:529-32. 2006..Ictal confusion, particularly if protracted, often presents a diagnostic challenge... - Clinical assessment of Axis I psychiatric morbidity in chronic epilepsy: a multicenter investigationJana E Jones
Department of Neurology, University of Wisconsin Madison, 53792 6180, USA
J Neuropsychiatry Clin Neurosci 17:172-9. 2005..Issues regarding recognition and treatment of psychiatric morbidity in epilepsy are discussed... - Diffusion tensor MRI in temporal lobe epilepsyKonstantinos Arfanakis
Department of Medical Physics, University of Wisconsin, Madison, WI, USA
Magn Reson Imaging 20:511-9. 2002..Furthermore, the age at onset of epilepsy may be an important factor in determining the extent of the effect of epilepsy on white matter... - Bone in idiopathic and symptomatic epilepsyRaj D Sheth
Department of Neurology, University of Wisconsin, Madison, WI 53792 5132, United States
Epilepsy Res 78:71-6. 2008..Non-ambulatory patients have reduced BMD, although, it is not clear if normally weight bearing ambulatory patients are similarly vulnerable... - Temporal lobe epilepsy and the selective reminding test: the conventional 30-minute delay sufficesBrian D Bell
Department of Neurology, University of Wisconsin Madison, Madison, WI 53792, USA
Psychol Assess 17:103-9. 2005..At the individual level, there was no difference in the percentage of patients versus controls who demonstrated isolated memory impairment at the 24-hr delay. Accelerated forgetting over 24 hr is uncommon in TLE patients... - Effects of simvastatin on cerebrospinal fluid biomarkers and cognition in middle-aged adults at risk for Alzheimer's diseaseCynthia M Carlsson
Department of Medicine, Section of Geriatrics and Gerontology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA
J Alzheimers Dis 13:187-97. 2008..It is unclear if statins modify Abeta metabolism or improve cognition in asymptomatic middle-aged adults at increased risk for AD... - Differential neuropsychological test sensitivity to left temporal lobe epilepsyDavid W Loring
Department of Neurology, University of Florida, Gainesville, Florida 32610, USA
J Int Neuropsychol Soc 14:394-400. 2008.... - Screening for major depression in epilepsy with common self-report depression inventoriesJana E Jones
Department of Neurology, University of Wisconsin Madison, 53792, USA
Epilepsia 46:731-5. 2005..The purpose of this study was to determine the ability of two common depressive symptom inventories to identify major depression in people with epilepsy... - Neuropsychological advocacy and epilepsyDavid W Loring
Department of Neurology, Emory University, Atlanta, GA 30322, USA
Clin Neuropsychol 24:417-28. 2010..We also include a seizure action plan, which is designed to be both an educational tool for individuals with limited epilepsy knowledge, and a way to minimize stigma associated with an event should a seizure occur during school or work... - Long-term psychosocial outcomes of anterior temporal lobectomyJana E Jones
Department of Neurology, University of Wisconsin Madison, Madison, Wisconsin 53792, U S A
Epilepsia 43:896-903. 2002..This study focused primarily on actual long-term changes (mean, 5 years) in life performance. There are relatively few long-term controlled studies of actual lifetime performance changes... - Significant discrepancies between immediate and delayed WMS-III indices are rare in temporal lobe epilepsy patientsBrian D Bell
Department of Neurology, University of Wisconsin Medical School, Madison, WI 53792, USA
Clin Neuropsychol 18:303-11. 2004..These data suggest that combining the appropriate WMS-III IMM and DEL memory subtest scores to form AUD and VIS memory indices is appropriate for TLE patients... - A review of carotid atherosclerosis and vascular cognitive decline: a new understanding of the keys to symptomologyRobert J Dempsey
University of Wisconsin School of Medicine and Public Health, Department of Neurological Surgery, Madison, Wisconsin 53792, USA
Neurosurgery 67:484-93; discussion 493-4. 2010..A linear relationship between the process of mechanically unstable areas of carotid plaques and cognitive decline suggests a contributory role for such a process in silent strokes... - Rates and risk factors for suicide, suicidal ideation, and suicide attempts in chronic epilepsyJana E Jones
Department of Neurology, University of Wisconsin Madison, Madison, WI, USA
Epilepsy Behav 4:S31-8. 2003..Assessing severity of risk helps to determine the appropriate level of intervention. The suicidality module of the Mini-International Neuropsychiatric Interview is a practical tool to help quantify current suicide risk... - Progressive bone deficit in epilepsyRaj D Sheth
Department of Neurology, University of Wisconsin Madison, 600 Highland Ave H6 574 CSC, Madison, WI 53792 5132, USA
Neurology 70:170-6. 2008..The objective was to determine the timing of the BMD deficit in ambulatory children with epilepsy... - Voxel-based morphometry of unilateral temporal lobe epilepsy reveals abnormalities in cerebral white matterAlan B McMillan
Department of Medical Physics, University of Wisconsin Madison, Madison, WI 53706, USA
Neuroimage 23:167-74. 2004.... - Visual and auditory naming in patients with left or bilateral temporal lobe epilepsyBrian D Bell
Department of Neurology, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792, USA
Epilepsy Res 55:29-37. 2003..Further study of the cognitive processes required during AN, its relation to word finding problems in discourse, and the effect of anterior temporal lobectomy on this ability is warranted... - Pathological fractures in epilepsyRaj D Sheth
Department of Neurology, University of Wisconsin Madison, Madison, WI 53792 5132, USA
Epilepsy Behav 9:601-5. 2006..Together these findings suggest that epilepsy, and/or its treatment, is a dominant influence in the pathogenesis of fractures and may exacerbate the effects of aging-related involutional osteoporosis... - The influence of Alzheimer disease family history and apolipoprotein E epsilon4 on mesial temporal lobe activationSterling C Johnson
University of Wisconsin Madison, Wisconsin 53705, USA
J Neurosci 26:6069-76. 2006.... - Screening for dementia in community-based memory clinicsMark A Sager
Wisconsin Alzheimer s Institute, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 53719, USA
WMJ 105:25-9. 2006..This study examined the usefulness of 3 brief screening tests in detecting dementia and mild cognitive impairment (MCI) in persons seeking consultation for memory complaints within a network of memory diagnostic clinics in Wisconsin... - Intractable epilepsy and patterns of psychiatric comorbidityBruce P Hermann
Department of Neurology, University of Wisconsin-Madison, Madison, Wisconsin, USA
Adv Neurol 97:367-74. 2006 - The relative impact of anxiety, depression, and clinical seizure features on health-related quality of life in epilepsyErica K Johnson
Department of Rehabilitation Psychology, University of Wisconsin, Madison, Wisconsin 53792, USA
Epilepsia 45:544-50. 2004..Recognition and treatment of comorbid depression and anxiety is an important consideration in improving quality of life in epilepsy... - Gender differences in bone mineral density in epilepsyRaj D Sheth
Department of Neurology, University of Wisconsin Madison, Madison, Wisconsin, USA
Epilepsia 49:125-31. 2008..Postmenopausal women are at highest risk, although, both men and premenopausal women with epilepsy experience adverse bone effects. We examined gender differences in bone density in epilepsy... - Bone mineral density with lamotrigine monotherapy for epilepsyRaj D Sheth
Department of Neurology, University of Wisconsin at Madison, Madison, Wisconsin 53792 5132, USA
Pediatr Neurol 37:250-4. 2007..006, P = 0.74) and >or=6 years of polytherapy (Spearman's correlation coefficient r = +0.12, P = 0.13), but not for lamotrigine. These data suggest that lamotrigine may not interfere with bone accrual... - Sleep architecture in children with idiopathic generalized epilepsyRama Maganti
Marshfield Clinic-Neurology, Wausau, Wisconsin 53792, USA
Epilepsia 46:104-9. 2005..CONCLUSIONS: Sleep architecture is abnormal in children with primary generalized epilepsy. Further studies are needed to determine whether abnormalities in sleep architecture contribute to poor daytime behavior and attention... - Memory for famous faces and the temporal pole: functional imaging findings in temporal lobe epilepsyH Randall Griffith
Department of Neurology, University of Alabama at Birmingham, AL, USA
Epilepsy Behav 9:173-80. 2006..Further study appears warranted to elucidate the networks involved in semantic knowledge for famous faces... - Neuropsychological predictors of academic underachievement in pediatric epilepsy: moderating roles of demographic, seizure, and psychosocial variablesPhilip S Fastenau
Department of Psychology, Purdue School of Science, Indiana University Purdue University Indianapolis, Indianapolis, Indiana, USA
Epilepsia 45:1261-72. 2004.... - Confirmatory factor analysis of the WMS-III in patients with temporal lobe epilepsyNancy J Wilde
Department of Psychology, University of Victoria, Victoria, P O Box 3050 STN CSC, Victoria, British Columbia V8W 3P5, Canada
Psychol Assess 15:56-63. 2003.... - Structural and functional neuroimaging correlates of depression in temporal lobe epilepsyElizabeth J Richardson
Department of Psychology, University of Alabama at Birmingham, Birmingham, AL, USA
Epilepsy Behav 10:242-9. 2007..Future studies examining the potential role of extended neural regions may clarify the observed structural relationship between depressive symptoms and the amygdala... - Living Well II: a review of progress since 2003Joan K Austin
Distinguished Professor, Indiana University School of Nursing, Indianapolis, Indiana, USA
Epilepsy Behav 9:386-93. 2006.... - Improving neuropsychological outcomes of epilepsy surgeryBruce P Hermann
Epilepsy Behav 13:5-6. 2008
Research Grants
- NEUROBEHAVIORAL FEATURES--MESIAL TEMPORAL LOBE EPILEPSYBruce Hermann; Fiscal Year: 2000....
- NEUROBEHAVIORAL FEATURES & MESIAL TEMPORAL LOBE EPILEPSYBruce Hermann; Fiscal Year: 2005..The findings will have potential implications for treatment as well as the understanding of the pathophysiology and natural history of TLE. ..
- Neurophychological Progression in New Onset EpilepsyBruce Hermann; Fiscal Year: 2007....
- Neuropsychological Progression of New Onset EpilepsyBRUCE PHILLIP HERMANN; Fiscal Year: 2010..3) Characterize abnormalities in baseline cerebral white matter and the clinical significance of identified abnormalities in new onset epilepsy. 2. ..