Hans H Herfarth

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. ncbi request reprint A case of recurrent gastrointestinal bleeding and protein-losing gastroenteropathy
    Hans Herfarth
    Department of Medicine, Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, NC 27599, USA
    Nat Clin Pract Gastroenterol Hepatol 4:288-93. 2007
  2. doi request reprint Role of probiotic therapy in IBD
    Kim Isaacs
    University of North Carolina at Chapel Hill, Division of Gastroenterology and Hepatology, Chapel Hill, NC 27599 7032, USA
    Inflamm Bowel Dis 14:1597-605. 2008
  3. doi request reprint Ciprofloxacin for the prevention of postoperative recurrence in patients with Crohn's disease: a randomized, double-blind, placebo-controlled pilot study
    Hans H Herfarth
    Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Inflamm Bowel Dis 19:1073-9. 2013
  4. doi request reprint The role of chemoprevention of colorectal cancer with 5-aminosalicylates in ulcerative colitis
    Hans Herfarth
    Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, NC 27599, USA
    Dig Dis 30:55-9. 2012
  5. pmc Frequency and significance of the novel single nucleotide missense polymorphism Val109Asp in the human gene encoding omentin in Caucasian patients with type 2 diabetes mellitus or chronic inflammatory bowel diseases
    Andreas Schaffler
    Department of Internal Medicine I, Regensburg University Medical Center, Germany
    Cardiovasc Diabetol 6:3. 2007
  6. pmc Evaluation of a non-invasive method to detect cytomegalovirus (CMV)-DNA in stool samples of patients with inflammatory bowel disease (IBD): a pilot study
    Hans H Herfarth
    Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina, Bioinformatics Bldg, CB 7080, Chapel Hill, NC, 27599, USA
    Dig Dis Sci 55:1053-8. 2010
  7. doi request reprint Are we ready for top-down therapy for inflammatory bowel diseases: con
    Hans Herfarth
    University of North Carolina School of Medicine, Division of Gastroenterology and Hepatology, Department of Medicine, Bioinformatics Bldg, CB 7080, Chapel Hill, NC 27599 7080, USA
    Expert Rev Gastroenterol Hepatol 1:249-55. 2007
  8. doi request reprint Risk of radiation and choice of imaging
    Hans Herfarth
    Department of Medicine, Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, NC 27599, USA
    Dig Dis 27:278-84. 2009
  9. pmc Efficacy of methotrexate in ulcerative colitis: failure or promise
    Hans H Herfarth
    Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Inflamm Bowel Dis 16:1421-30. 2010
  10. pmc Frequency and nature of incidental extra-enteric lesions found on magnetic resonance enterography (MR-E) in patients with inflammatory bowel diseases (IBD)
    Hans H Herfarth
    Department of Internal Medicine, University of Regensburg, Regensburg, Germany
    PLoS ONE 4:e4863. 2009

Detail Information

Publications51

  1. ncbi request reprint A case of recurrent gastrointestinal bleeding and protein-losing gastroenteropathy
    Hans Herfarth
    Department of Medicine, Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, NC 27599, USA
    Nat Clin Pract Gastroenterol Hepatol 4:288-93. 2007
    ..He had recently recovered from a heart operation, which was performed to reconstruct the right ventricular outflow tract...
  2. doi request reprint Role of probiotic therapy in IBD
    Kim Isaacs
    University of North Carolina at Chapel Hill, Division of Gastroenterology and Hepatology, Chapel Hill, NC 27599 7032, USA
    Inflamm Bowel Dis 14:1597-605. 2008
    ..This review examines the data of all fully published articles currently available for the role of probiotics in the treatment of IBD...
  3. doi request reprint Ciprofloxacin for the prevention of postoperative recurrence in patients with Crohn's disease: a randomized, double-blind, placebo-controlled pilot study
    Hans H Herfarth
    Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Inflamm Bowel Dis 19:1073-9. 2013
    ..We conducted a randomized, double-blind, placebo-controlled 6-month pilot trial of ciprofloxacin for the prevention of endoscopic recurrence in patients with CD who underwent surgery...
  4. doi request reprint The role of chemoprevention of colorectal cancer with 5-aminosalicylates in ulcerative colitis
    Hans Herfarth
    Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, NC 27599, USA
    Dig Dis 30:55-9. 2012
    ..Currently, it appears that 5-ASA have no or only a very limited effect as a deterrence against CRC. Thus, a general recommendation for long-term use of 5-ASA solely for chemopreventive measures is not warranted...
  5. pmc Frequency and significance of the novel single nucleotide missense polymorphism Val109Asp in the human gene encoding omentin in Caucasian patients with type 2 diabetes mellitus or chronic inflammatory bowel diseases
    Andreas Schaffler
    Department of Internal Medicine I, Regensburg University Medical Center, Germany
    Cardiovasc Diabetol 6:3. 2007
    ..Omentin represents a new adipokine expressed in and secreted by omental adipose tissue. Therefore, it was the aim to investigate the putative role of a newly described sequence missense variation in the human omentin gene...
  6. pmc Evaluation of a non-invasive method to detect cytomegalovirus (CMV)-DNA in stool samples of patients with inflammatory bowel disease (IBD): a pilot study
    Hans H Herfarth
    Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina, Bioinformatics Bldg, CB 7080, Chapel Hill, NC, 27599, USA
    Dig Dis Sci 55:1053-8. 2010
    ..The aim of this pilot study was to investigate the diagnostic efficacy of quantitative polymerase chain reaction (PCR) to detect CMV DNA in stool samples of IBD patients...
  7. doi request reprint Are we ready for top-down therapy for inflammatory bowel diseases: con
    Hans Herfarth
    University of North Carolina School of Medicine, Division of Gastroenterology and Hepatology, Department of Medicine, Bioinformatics Bldg, CB 7080, Chapel Hill, NC 27599 7080, USA
    Expert Rev Gastroenterol Hepatol 1:249-55. 2007
    ....
  8. doi request reprint Risk of radiation and choice of imaging
    Hans Herfarth
    Department of Medicine, Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, NC 27599, USA
    Dig Dis 27:278-84. 2009
    ..We also need to identify subsets of IBD patients who are at greater risk of a significant lifetime exposure to radiation and develop methods to monitor their radiation exposure rate...
  9. pmc Efficacy of methotrexate in ulcerative colitis: failure or promise
    Hans H Herfarth
    Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Inflamm Bowel Dis 16:1421-30. 2010
    ....
  10. pmc Frequency and nature of incidental extra-enteric lesions found on magnetic resonance enterography (MR-E) in patients with inflammatory bowel diseases (IBD)
    Hans H Herfarth
    Department of Internal Medicine, University of Regensburg, Regensburg, Germany
    PLoS ONE 4:e4863. 2009
    ..The aim of this study was to determine the occurrence of extra-enteric findings in a large cohort of patients undergoing magnetic resonance enterography (MR-E) and to classify the clinical significance of these findings...
  11. doi request reprint Capsule and balloon endoscopy: When are they really needed in patients with inflammatory bowel diseases?
    Hans H Herfarth
    Department of Medicine, Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Dig Dis 28:439-44. 2010
    ..This review summarizes the current clinical status of capsule and balloon enteroscopy in patients with suspected or established IBD...
  12. pmc Risk of melanoma and nonmelanoma skin cancer among patients with inflammatory bowel disease
    Millie D Long
    Department of Medicine, University of North Carolina, Chapel Hill, NC, USA
    Gastroenterology 143:390-399.e1. 2012
    ..Patients with inflammatory bowel disease (IBD) are at risk for certain malignancies. We aimed to determine the risk of melanoma and nonmelanoma skin cancer (NMSC) in patients with IBD and how medications affect these risks...
  13. pmc NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling
    Irving C Allen
    Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Immunity 36:742-54. 2012
    ..NLRP12 interacted with both NIK and TRAF3, and Nlrp12(-/-) cells have constitutively elevated NIK, p100 processing to p52 and reduced TRAF3. Thus, NLRP12 is a checkpoint of noncanonical NF-κB, inflammation, and tumorigenesis...
  14. pmc Gnotobiotic IL-10; NF-kappaB mice develop rapid and severe colitis following Campylobacter jejuni infection
    Elisabeth Lippert
    Department of Medicine and Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
    PLoS ONE 4:e7413. 2009
    ..jejuni induced colonic inflammation. Our findings indicate that C. jejuni induces rapid and severe intestinal inflammation in a susceptible host that correlates with enhanced NF-kappaB activity from lamina propria immune cells...
  15. doi request reprint Oral budesonide for the therapy of post-liver transplant de novo inflammatory bowel disease: a case series and systematic review of the literature
    A Sidney Barritt
    Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, North Carolina 27599 7080, USA
    Inflamm Bowel Dis 14:1695-700. 2008
    ..Budesonide, a luminally active steroid with low systemic absorption, is an established therapeutic agent for IBD that should receive special considerations as first-line therapy in this patient population...
  16. pmc Tomato lycopene extract prevents lipopolysaccharide-induced NF-kappaB signaling but worsens dextran sulfate sodium-induced colitis in NF-kappaBEGFP mice
    Young Eun Joo
    Department of Medicine and Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
    PLoS ONE 4:e4562. 2009
    ..The impact of tomato lycopene extract (TLE) on intestinal inflammation is currently unknown. We investigated the effect of TLE on lipopolysaccharide (LPS)-induced innate signaling and experimental colitis...
  17. doi request reprint Reduced polyp detection as endoscopy shift progresses: experience with screening colonoscopy at a tertiary-care hospital
    Millie D Long
    Department of Medicine, Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7080, USA
    J Clin Gastroenterol 45:253-8. 2011
    ..To determine whether polyp detection rates are reduced as time progresses through half and full-day endoscopy shifts...
  18. ncbi request reprint Prevalence of a Gluten-free Diet and Improvement of Clinical Symptoms in Patients with Inflammatory Bowel Diseases
    Hans H Herfarth
    Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina and Department of Pediatrics, University of North Carolina, Chapel Hill, North Carolina
    Inflamm Bowel Dis 20:1194-7. 2014
    ..Maintaining a gluten-free diet (GFD) without an underlying diagnosis of celiac disease has enjoyed widespread acceptance in the Unites States...
  19. ncbi request reprint Comparison of interobserver agreement for different scoring systems for reflux esophagitis: Impact of level of experience
    Heiko C Rath
    Department of Internal Medicine I, University of Regensburg, Regensburg, Germany
    Gastrointest Endosc 60:44-9. 2004
    ..Interobserver agreement for these systems was compared, with particular reference to the experience of the endoscopist...
  20. doi request reprint Methotrexate: underused and ignored?
    Hans H Herfarth
    Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, NC 27599, USA hherf med unc edu
    Dig Dis 30:112-8. 2012
    ..This review investigates the potential reasons for the underuse of methotrexate in patients with inflammatory bowel diseases...
  21. pmc The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
    Irving C Allen
    Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    J Exp Med 207:1045-56. 2010
    ..These data suggest that the inflammasome functions as an attenuator of colitis and CAC...
  22. pmc Increased risk for non-melanoma skin cancer in patients with inflammatory bowel disease
    Millie D Long
    Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, North Carolina 27599 7080, USA
    Clin Gastroenterol Hepatol 8:268-74. 2010
    ..We evaluated the risk of non-melanoma skin cancer (NMSC) in patients with IBD and determined how immunosuppressive and biologic medications affect this risk...
  23. pmc Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility
    Joshua M Uronis
    Department of Medicine and Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    PLoS ONE 4:e6026. 2009
    ....
  24. pmc Impact of capsule endoscopy on management of inflammatory bowel disease: a single tertiary care center experience
    Millie D Long
    University of North Carolina at Chapel Hill, Division of Gastroenterology and Hepatology, Chapel Hill, North Carolina 27599 7080, USA
    Inflamm Bowel Dis 17:1855-62. 2011
    ..Capsule endoscopy (CE) is performed to assess inflammatory bowel disease (IBD). We aimed to define the results of CE in subtypes of IBD and to determine whether CE results in management changes...
  25. pmc Diagnostic ionizing radiation exposure in a population-based sample of children with inflammatory bowel diseases
    Lena Palmer
    Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Am J Gastroenterol 104:2816-23. 2009
    ..In this study, we describe this exposure in a population-based sample of children with IBD and determine the characteristics associated with moderate radiation exposure...
  26. ncbi request reprint Flat colorectal cancers are genetically determined and progress to invasion without going through a polypoid stage
    Joshua M Uronis
    Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Cancer Res 67:11594-600. 2007
    ....
  27. pmc Narcotic use for inflammatory bowel disease and risk factors during hospitalization
    Millie D Long
    Department of Medicine, Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7080, USA
    Inflamm Bowel Dis 18:869-76. 2012
    ..We sought to study the relationship between narcotic use, objective measures of disease activity, and other associated factors in hospitalized patients with IBD...
  28. doi request reprint The role of domestic hygiene in inflammatory bowel diseases: hepatitis A and worm infestations
    Stefan Hafner
    Department of Internal Medicine I, University of Regensburg, Regensburg, Germany
    Eur J Gastroenterol Hepatol 20:561-6. 2008
    ....
  29. ncbi request reprint Can OCT be used to distinguish accurately between patients with ulcerative colitis and those with Crohn's disease?
    Hans Herfarth
    University of Regensburg, Germany
    Nat Clin Pract Gastroenterol Hepatol 2:172-3. 2005
  30. pmc Lactobacillus GG in inducing and maintaining remission of Crohn's disease
    Michael Schultz
    Department of Internal Medicine I, University of Regensburg, Regensburg, Germany
    BMC Gastroenterol 4:5. 2004
    ..The aim of this randomized, placebo-controlled trial was to determine the effect of oral Lactobacillus GG (L. GG) to induce or maintain medically induced remission...
  31. pmc Prevalence and epidemiology of overweight and obesity in children with inflammatory bowel disease
    Millie D Long
    University of North Carolina at Chapel Hill, Department of Medicine, Division of Gastroenterology and Hepatology, Chapel Hill, North Carolina 27599 7080, USA
    Inflamm Bowel Dis 17:2162-8. 2011
    ....
  32. ncbi request reprint A critical evaluation of serologic markers for inflammatory bowel disease
    Gregory L Austin
    Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, North Carolina, USA
    Clin Gastroenterol Hepatol 5:545-7. 2007
  33. ncbi request reprint Optimising the diagnostic value of anti-Saccharomyces cerevisiae-antibodies (ASCA) in Crohn's disease
    Frank H Klebl
    Department of Internal Medicine I, University of Regensburg, 93042, Regensburg, Germany
    Int J Colorectal Dis 19:319-24. 2004
    ..ASCA tests are not standardised and different methods for ASCA detection exist. This study was undertaken to compare ASCA tests and to clarify their diagnostic value...
  34. ncbi request reprint New diagnostic avenues in inflammatory bowel diseases. Capsule endoscopy, magnetic resonance imaging and virtual enteroscopy
    Andreas G Schreyer
    Department of Radiology, University of Regensburg, Regensburg, Germany
    Dig Dis 21:129-37. 2003
    ..This article describes these recently introduced methods in the diagnostic assessment of the small bowel and discusses the clinical significance based on the current literature...
  35. ncbi request reprint Comparison of capsule endoscopy and magnetic resonance (MR) enteroclysis in suspected small bowel disease
    Stefan K Gölder
    Department of Internal Medicine I, University of Regensburg, 93042, Regensburg, Germany
    Int J Colorectal Dis 21:97-104. 2006
    ..The aim of this study was to compare the diagnostic yield of WCE with MR enteroclysis in the detection of small bowel pathologies...
  36. ncbi request reprint Vascular endothelial growth factor secretion from mesenteric adipose tissue and from creeping fat in Crohn's disease
    Andreas Schaffler
    Department of Internal Medicine I, University of Regensburg, Regensburg, Germany
    J Gastroenterol Hepatol 21:1419-23. 2006
    ..Because VEGF serum levels and mucosal VEGF expression is elevated in CD patients, the aim of the present paper was to investigate creeping fat-derived VEGF secretion in CD...
  37. ncbi request reprint Serum soluble TNF receptor I and II levels correlate with disease activity in IBD patients
    Tanja Spoettl
    Department of Internal Medicine I, University of Regensburg, Germany
    Inflamm Bowel Dis 13:727-32. 2007
    ..Soluble TNF receptors I and II (sTNF-RI + II) are released by proteolytic cleavage of the extracellular domains of these receptors. Soluble TNF-Rs act as TNF antagonists and can inhibit TNFalpha-mediated proinflammatory effects...
  38. ncbi request reprint Secretion of RANTES (CCL5) and interleukin-10 from mesenteric adipose tissue and from creeping fat in Crohn's disease: regulation by steroid treatment
    Andreas Schaffler
    Department of Internal Medicine I, University of Regensburg, Regensburg, Germany
    J Gastroenterol Hepatol 21:1412-8. 2006
    ..Pro- or anti-inflammatory adipose tissue-derived secretory products (adipocytokines) might play a role in the pathogenesis of CD...
  39. doi request reprint Evidence for a role of epithelial mesenchymal transition during pathogenesis of fistulae in Crohn's disease
    Frauke Bataille
    Institute of Pathology, University of Regensburg, Regensburg, Germany
    Inflamm Bowel Dis 14:1514-27. 2008
    ..EMT has been suggested to be crucial in fibrosis found in different tissues and diseases. We therefore investigated whether EMT could be involved in the pathogenesis of fistulae formation in CD...
  40. ncbi request reprint Association of perinuclear antineutrophil cytoplasmic antibodies and anti-Saccharomyces cerevisiae antibodies with Vienna classification subtypes of Crohn's disease
    Frank H Klebl
    Department of Internal Medicine I, dagger Institute of Pathology, University of Regensburg, Regensburg, Germany
    Inflamm Bowel Dis 9:302-7. 2003
    ..AIM The aim of this study was to test whether perinuclear antineutrophil cytoplasmic antibodies (pANCAs) or anti-Saccharomyces cerevisiae antibodies (ASCAs) correlate to subtypes of CD according to this classification...
  41. ncbi request reprint Profiling adipocytokine secretion from creeping fat in Crohn's disease
    Gisela Paul
    Department of Internal Medicine I, University of Regensburg, Regensburg, Germany
    Inflamm Bowel Dis 12:471-7. 2006
    ..Creeping fat represents a characteristic feature of Crohn's disease (CD). Proinflammatory or anti-inflammatory adipose-derived secretory products, now generally called adipocytokines, may play a role in the pathogenesis of CD...
  42. ncbi request reprint Prognostic significance of NOD2/CARD15 variants in HLA-identical sibling hematopoietic stem cell transplantation: effect on long-term outcome is confirmed in 2 independent cohorts and may be modulated by the type of gastrointestinal decontamination
    Ernst Holler
    Department of Haematology Oncology, Medical Centre, University of Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Blood 107:4189-93. 2006
    ..Our data further support an interaction between gastrointestinal defense mechanisms, activation of the innate immune system, and specific transplant-related complications...
  43. doi request reprint Gene expression profiles of mucosal fibroblasts from strictured and nonstrictured areas of patients with Crohn's disease
    Markus Lang
    Department of Internal Medicine I, University of Regensburg, Regensburg, Germany
    Inflamm Bowel Dis 15:212-23. 2009
    ..We aimed to investigate differences in gene expression profiles between CLPF isolated from normal, inflamed and strictured areas of CD patients...
  44. doi request reprint The functional-organic dichotomy: postinfectious irritable bowel syndrome and inflammatory bowel disease-irritable bowel syndrome
    Madhusudan Grover
    Center for Functional GI and Motility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7080, USA
    Clin Gastroenterol Hepatol 7:48-53. 2009
    ..It obligates us to reframe our understanding of illness and disease from the dualistic biomedical model into a more integrated biopsychosocial (BPS) perspective...
  45. ncbi request reprint Functional expression of the interleukin-11 receptor alpha-chain in normal colonic epithelium and colon cancer
    Nicole Deutscher
    Department of Internal Medicine I, University of Regensburg, 93042 Regensburg, Germany
    Int J Colorectal Dis 21:573-81. 2006
    ..The aim of this study was to investigate the expression profiling of IL-11Ralpha and its downstream signaling cascade in colonic adenoma and carcinoma...
  46. ncbi request reprint Abdominal MRI after enteroclysis or with oral contrast in patients with suspected or proven Crohn's disease
    Andreas G Schreyer
    Department of Radiology, University of Regensburg, Germany
    Clin Gastroenterol Hepatol 2:491-7. 2004
    ....
  47. ncbi request reprint Polymorphism of monocyte chemoattractant protein 1 in Crohn's disease
    Hans Herfarth
    Department of Internal Medicine I, University of Regensburg, 93042 Regensburg, Germany
    Int J Colorectal Dis 18:401-5. 2003
    ..Furthermore, we studied whether a functional single nucleotide polymorphism (G or A) located in the distal regulatory region of the MCP-1 gene is associated with Crohn's disease and/or its phenotype...
  48. ncbi request reprint Controlled, open, randomized multicenter trial comparing the effects of treatment on quality of life, safety and efficacy of budesonide foam and betamethasone enemas in patients with active distal ulcerative colitis
    Angela Hammond
    Department of Internal Medicine I, University of Regensburg, Regensburg, Germany
    Hepatogastroenterology 51:1345-9. 2004
    ..The purpose of this study was to assess the effect of treatment with budesonide foam or betamethasone enema on the quality of life and the clinical outcome in patients with distal ulcerative colitis...
  49. ncbi request reprint Dark lumen magnetic resonance enteroclysis in combination with MRI colonography for whole bowel assessment in patients with Crohn's disease: first clinical experience
    Andreas G Schreyer
    Department of Radiology, University Hospital Regensburg, Regensburg, Germany
    Inflamm Bowel Dis 11:388-94. 2005
    ..In this feasibility study, we evaluated the combination of small bowel MRI with unprepared MRC as an integrative diagnostic approach of the whole bowel in patients with Crohn's disease...
  50. ncbi request reprint Rapamycin decreases leukocyte migration in vivo and effectively reduces experimentally induced chronic colitis
    Stefan Farkas
    Department of Surgery, University of Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Int J Colorectal Dis 21:747-53. 2006
    ..The aim of the present study was to test the immunosuppressive mammalian target of rapamycin inhibitor rapamycin in an experimental model of chronic colitis and to compare its effectiveness with CsA...
  51. ncbi request reprint Blocking MAdCAM-1 in vivo reduces leukocyte extravasation and reverses chronic inflammation in experimental colitis
    Stefan Farkas
    Department of Surgery, University of Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Int J Colorectal Dis 21:71-8. 2006
    ..Here, we investigate the pathophysiologic role of MAdCAM-1 in the intestinal microcirculation in vivo...

Research Grants2

  1. Pilot study on the safety and efficacy of ciprofloxacin for prophylactic preventi
    Hans Herfarth; Fiscal Year: 2007
    ..The clinical data generated by this study will serve as a basis for a definitive clinical trial investigating the effectiveness of ciprofloxacin in the prevention of endoscopic recurrence in postoperative Crohn's disease. ..