Affiliation: University of Arizona
Henriksen E, Kinnick T, Teachey M, O Keefe M, Ring D, Johnson K, et al
. Modulation of muscle insulin resistance by selective inhibition of GSK-3 in Zucker diabetic fatty rats. Am J Physiol Endocrinol Metab. 2003;284:E892-900 pubmed
..This unique approach may hold promise as a pharmacological treatment against insulin resistance of skeletal muscle glucose disposal. ..
Henriksen E, Jacob S, Kinnick T, Youngblood E, Schmit M, Dietze G. ACE inhibition and glucose transport in insulinresistant muscle: roles of bradykinin and nitric oxide. Am J Physiol. 1999;277:R332-6 pubmed
..Moreover, this modulation of insulin action by BK is likely mediated through B(2) receptors and by an increase in nitric oxide production and/or action in skeletal muscle tissue. ..
Henriksen E, Diamond Stanic M, Marchionne E. Oxidative stress and the etiology of insulin resistance and type 2 diabetes. Free Radic Biol Med. 2011;51:993-9 pubmed publisher
..Strategies to prevent and ameliorate oxidative stress remain important in the overall treatment of insulin resistance and type 2 diabetes. ..
Henriksen E. Effects of H2O2 on insulin signaling the glucose transport system in mammalian skeletal muscle. Methods Enzymol. 2013;528:269-78 pubmed publisher
..By varying the glucose oxidase concentration in the medium, target ranges of steady-state H2O2 concentrations (30-90 ?M) can be attained for up to 6h, with subsequent assessment of cellular signaling and glucose transport activity. ..