I R Henderson

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. pmc Characterization of pic, a secreted protease of Shigella flexneri and enteroaggregative Escherichia coli
    I R Henderson
    Center for Vaccine Development, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Infect Immun 67:5587-96. 1999
  2. ncbi request reprint Molecular switches--the ON and OFF of bacterial phase variation
    I R Henderson
    Center for Vaccine Development, Department of Pediatrics, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, MD 21201, USA
    Mol Microbiol 33:919-32. 1999
  3. ncbi request reprint Identification of sat, an autotransporter toxin produced by uropathogenic Escherichia coli
    D M Guyer
    Department of Microbiology and Immunology, and Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Mol Microbiol 38:53-66. 2000
  4. pmc The sigA gene which is borne on the she pathogenicity island of Shigella flexneri 2a encodes an exported cytopathic protease involved in intestinal fluid accumulation
    K Al-Hasani
    Department of Microbiology, Monash University, Clayton, Victoria 3800, Australia
    Infect Immun 68:2457-63. 2000
  5. ncbi request reprint Antigen 43, a phase-variable bipartite outer membrane protein, determines colony morphology and autoaggregation in Escherichia coli K-12
    I R Henderson
    Department of Microbiology, Moyne Institute of Preventive Medicine, Trinity College Dublin, Ireland
    FEMS Microbiol Lett 149:115-20. 1997
  6. ncbi request reprint A novel regulatory mechanism for a novel phase-variable outer membrane protein of Escherichia coli
    I R Henderson
    Department of Microbiology, Moyne Institute of Preventive Medicine, Trinity College Dublin, Ireland
    Adv Exp Med Biol 412:349-55. 1997
  7. pmc The major phase-variable outer membrane protein of Escherichia coli structurally resembles the immunoglobulin A1 protease class of exported protein and is regulated by a novel mechanism involving Dam and oxyR
    I R Henderson
    Department of Microbiology, Moyne Institute of Preventive Medicine, Trinity College Dublin, Dublin 2, Ireland
    J Bacteriol 181:2132-41. 1999

Collaborators

  • C Eslava
  • D M Guyer
  • J P Nataro
  • K Al-Hasani
  • R Robins-Browne
  • H Sakellaris
  • T Grant
  • B Adler
  • K Rajakumar
  • H L Mobley

Detail Information

Publications7

  1. pmc Characterization of pic, a secreted protease of Shigella flexneri and enteroaggregative Escherichia coli
    I R Henderson
    Center for Vaccine Development, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Infect Immun 67:5587-96. 1999
    ..Functional analysis of the Pic protein implicates this factor in mucinase activity, serum resistance, and hemagglutination. Our data suggest that Pic may be a multifunctional protein involved in enteric pathogenesis...
  2. ncbi request reprint Molecular switches--the ON and OFF of bacterial phase variation
    I R Henderson
    Center for Vaccine Development, Department of Pediatrics, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, MD 21201, USA
    Mol Microbiol 33:919-32. 1999
    ..Phase variation events are usually random, but may be modulated by environmental conditions. The mechanisms of phase variation events and their significance within the microbial community are discussed here...
  3. ncbi request reprint Identification of sat, an autotransporter toxin produced by uropathogenic Escherichia coli
    D M Guyer
    Department of Microbiology and Immunology, and Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Mol Microbiol 38:53-66. 2000
    ..Based upon its association with pathogenic isolates, its cytopathic phenotype and its ability to elicit a strong antibody response after infection, we postulate that Sat represents a novel virulence determinant of uropathogenic E. coli...
  4. pmc The sigA gene which is borne on the she pathogenicity island of Shigella flexneri 2a encodes an exported cytopathic protease involved in intestinal fluid accumulation
    K Al-Hasani
    Department of Microbiology, Monash University, Clayton, Victoria 3800, Australia
    Infect Immun 68:2457-63. 2000
    ..SigA was at least partly responsible for the ability of S. flexneri to stimulate fluid accumulation in ligated rabbit ileal loops...
  5. ncbi request reprint Antigen 43, a phase-variable bipartite outer membrane protein, determines colony morphology and autoaggregation in Escherichia coli K-12
    I R Henderson
    Department of Microbiology, Moyne Institute of Preventive Medicine, Trinity College Dublin, Ireland
    FEMS Microbiol Lett 149:115-20. 1997
    ..coli chromosome previously established for flu...
  6. ncbi request reprint A novel regulatory mechanism for a novel phase-variable outer membrane protein of Escherichia coli
    I R Henderson
    Department of Microbiology, Moyne Institute of Preventive Medicine, Trinity College Dublin, Ireland
    Adv Exp Med Biol 412:349-55. 1997
    ..Sequencing and mapping has identified Ag43 as the likely product of the metastable flu gene first described in 1980 by Diderichsen and responsible for colony form variation in E. coli...
  7. pmc The major phase-variable outer membrane protein of Escherichia coli structurally resembles the immunoglobulin A1 protease class of exported protein and is regulated by a novel mechanism involving Dam and oxyR
    I R Henderson
    Department of Microbiology, Moyne Institute of Preventive Medicine, Trinity College Dublin, Dublin 2, Ireland
    J Bacteriol 181:2132-41. 1999
    ..We propose a novel mechanism for the regulation of phase switching in which OxyR competes with Dam for unmethylated GATC sites in the regulatory region of the agn43 gene...