JESSE C HEMPHILL

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Do-not-resuscitate orders, unintended consequences, and the ripple effect
    J Claude Hemphill
    Department of Neurology, Room 4M62, San Francisco General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110, USA
    Crit Care 11:121. 2007
  2. ncbi request reprint International neurocritical care: report from the Costa Rica Neurointensive and Neuromonitoring Course
    J Claude Hemphill
    Department of Neurology, San Francisco General Hospital, Room 4M62, 1001 Potrero Avenue, San Francisco, CA 94110, USA
    Neurocrit Care 8:308-9. 2008
  3. pmc Clinical nihilism in neuroemergencies
    J Claude Hemphill
    Department of Neurology, San Francisco General Hospital, University of California, San Francisco, CA 94110, USA
    Emerg Med Clin North Am 27:27-37, vii-viii. 2009
  4. pmc Prospective validation of the ICH Score for 12-month functional outcome
    J Claude Hemphill
    Department of Neurology, University of California, San Francisco, USA
    Neurology 73:1088-94. 2009
  5. doi request reprint Multimodal monitoring and neurocritical care bioinformatics
    J Claude Hemphill
    Department of Neurology, Brain and Spinal Injury Center, San Francisco General Hospital, Room 4M62, 1001 Potrero Avenue, San Francisco, CA 94110, USA
    Nat Rev Neurol 7:451-60. 2011
  6. ncbi request reprint A novel method of evaluating the impact of secondary brain insults on functional outcomes in traumatic brain-injured patients
    Christopher W Barton
    Department of Medicine, University of California, San Francisco, CA 94110, USA
    Acad Emerg Med 12:1-6. 2005
  7. doi request reprint Post-operative expansion of hemorrhagic contusions after unilateral decompressive hemicraniectomy in severe traumatic brain injury
    Alexander C Flint
    Department of Neurology, Neurovascular and Neurocritical Care Service, University of California San Francisco, San Francisco General Hospital, San Francisco, California 94110, USA
    J Neurotrauma 25:503-12. 2008
  8. ncbi request reprint Cumulative dose of hypertension predicts outcome in intracranial hemorrhage better than American Heart Association guidelines
    Christopher W Barton
    Department of Medicine, University of California, San Francisco, San Francisco, CA, USA
    Acad Emerg Med 14:695-701. 2007
  9. ncbi request reprint The spontaneous breathing pattern and work of breathing of patients with acute respiratory distress syndrome and acute lung injury
    Richard H Kallet
    Critical Care Division, Department of Anesthesia, University of California, San Francisco General Hospital, NH GA 2, 1001 Potrero Avenue, San Francisco CA 94110, USA
    Respir Care 52:989-95. 2007
  10. ncbi request reprint Prognostic significance of angiographically confirmed large vessel intracranial occlusion in patients presenting with acute brain ischemia
    Wade S Smith
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Neurocrit Care 4:14-7. 2006

Research Grants

Collaborators

Detail Information

Publications35

  1. pmc Do-not-resuscitate orders, unintended consequences, and the ripple effect
    J Claude Hemphill
    Department of Neurology, Room 4M62, San Francisco General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110, USA
    Crit Care 11:121. 2007
    ..As illustrated by the example of intracerebral hemorrhage, this may unexpectedly influence outcome even in patients without DNR orders in place...
  2. ncbi request reprint International neurocritical care: report from the Costa Rica Neurointensive and Neuromonitoring Course
    J Claude Hemphill
    Department of Neurology, San Francisco General Hospital, Room 4M62, 1001 Potrero Avenue, San Francisco, CA 94110, USA
    Neurocrit Care 8:308-9. 2008
  3. pmc Clinical nihilism in neuroemergencies
    J Claude Hemphill
    Department of Neurology, San Francisco General Hospital, University of California, San Francisco, CA 94110, USA
    Emerg Med Clin North Am 27:27-37, vii-viii. 2009
    ....
  4. pmc Prospective validation of the ICH Score for 12-month functional outcome
    J Claude Hemphill
    Department of Neurology, University of California, San Francisco, USA
    Neurology 73:1088-94. 2009
    ..The goals of this study were to assess whether the ICH Score accurately stratifies patients with regard to 12-month functional outcome and to further delineate the pace of recovery of patients during the first year post-ICH...
  5. doi request reprint Multimodal monitoring and neurocritical care bioinformatics
    J Claude Hemphill
    Department of Neurology, Brain and Spinal Injury Center, San Francisco General Hospital, Room 4M62, 1001 Potrero Avenue, San Francisco, CA 94110, USA
    Nat Rev Neurol 7:451-60. 2011
    ....
  6. ncbi request reprint A novel method of evaluating the impact of secondary brain insults on functional outcomes in traumatic brain-injured patients
    Christopher W Barton
    Department of Medicine, University of California, San Francisco, CA 94110, USA
    Acad Emerg Med 12:1-6. 2005
    ..The authors hypothesized that a new method that accounts for the cumulative depth and duration of SBIs would provide a more informative measure that better correlates with outcome...
  7. doi request reprint Post-operative expansion of hemorrhagic contusions after unilateral decompressive hemicraniectomy in severe traumatic brain injury
    Alexander C Flint
    Department of Neurology, Neurovascular and Neurocritical Care Service, University of California San Francisco, San Francisco General Hospital, San Francisco, California 94110, USA
    J Neurotrauma 25:503-12. 2008
    ..Severity of initial CT findings may predict the risk of contusion expansion following hemicraniectomy, thereby identifying a subgroup of patients who might benefit from therapies aimed at augmenting the coagulation system...
  8. ncbi request reprint Cumulative dose of hypertension predicts outcome in intracranial hemorrhage better than American Heart Association guidelines
    Christopher W Barton
    Department of Medicine, University of California, San Francisco, San Francisco, CA, USA
    Acad Emerg Med 14:695-701. 2007
    ..The American Heart Association recommends that blood pressure be maintained at a mean arterial pressure (MAP) less than 130 mm Hg to prevent secondary brain injury...
  9. ncbi request reprint The spontaneous breathing pattern and work of breathing of patients with acute respiratory distress syndrome and acute lung injury
    Richard H Kallet
    Critical Care Division, Department of Anesthesia, University of California, San Francisco General Hospital, NH GA 2, 1001 Potrero Avenue, San Francisco CA 94110, USA
    Respir Care 52:989-95. 2007
    ..We examined the relationship between f/VT, WOB, and respiratory system mechanics in patients with ARDS/ALI...
  10. ncbi request reprint Prognostic significance of angiographically confirmed large vessel intracranial occlusion in patients presenting with acute brain ischemia
    Wade S Smith
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Neurocrit Care 4:14-7. 2006
    ..Because large-vessel occlusion and stroke severity are likely correlated, it is unclear if largevessel occlusion independently predicts outcome or is simply a marker for stroke severity...
  11. ncbi request reprint Report from the Indian Third National Workshop on Critical Care Neurology
    J Claude Hemphill
    Department of Neurology, San Francisco General Hospital, San Francisco, CA 94110, USA
    Neurocrit Care 3:282-3. 2005
  12. ncbi request reprint Brain tissue oxygen monitoring in intracerebral hemorrhage
    J Claude Hemphill
    Department of Neurology, University of California, San Francisco, CA, 94110, USA
    Neurocrit Care 3:260-70. 2005
    ..We report complementary preliminary studies in a large animal model and in patients that demonstrate the feasibility of PbrO2 monitoring after ICH...
  13. ncbi request reprint Diagnosis of posttraumatic transverse sinus thrombosis with magnetic resonance imaging/magnetic resonance venography: report of two cases
    Alfredo Quinones-Hinojosa
    Department of Neurosurgery, San Francisco General Hospital, University of California, 94143 0112, USA
    J Trauma 56:201-4. 2004
  14. ncbi request reprint Influence of data resolution and interpolation method on assessment of secondary brain insults in neurocritical care
    J Claude Hemphill
    Department of Neurology, University of California, San Francisco, CA, USA San Francisco Injury Center, San Francisco, CA, USA
    Physiol Meas 26:373-86. 2005
    ..High frequency data acquisition may be necessary for more precise evaluation of secondary brain injury in neurocritical care...
  15. doi request reprint Hypertonic saline versus mannitol for the treatment of elevated intracranial pressure: a meta-analysis of randomized clinical trials
    Hooman Kamel
    Department of Neurology, University of California, San Francisco, CA, USA
    Crit Care Med 39:554-9. 2011
    ..We therefore combined their findings in a meta-analysis...
  16. ncbi request reprint Hospital usage of early do-not-resuscitate orders and outcome after intracerebral hemorrhage
    J Claude Hemphill
    Department of Neurology, University of California, San Francisco, Calif, USA
    Stroke 35:1130-4. 2004
    ..Do-not-resuscitate (DNR) orders are commonly used after severe stroke. We hypothesized that there is significant variability in how these orders are applied after intracerebral hemorrhage and that this influences outcome...
  17. ncbi request reprint New approaches to physiological informatics in neurocritical care
    MARCO D SORANI
    Program in Biological and Medical Informatics, University of California, San Francisco, USA
    Neurocrit Care 7:45-52. 2007
    ..We propose that advances in monitoring must be accompanied by advances in methods of high-frequency, multivariate data analysis that integrate the multiple processes occurring in critically ill patients...
  18. doi request reprint Brain tissue oxygen tension is more indicative of oxygen diffusion than oxygen delivery and metabolism in patients with traumatic brain injury
    Guy Rosenthal
    Department of Neurosurgery, University of California, San Francisco, USA
    Crit Care Med 36:1917-24. 2008
    ..The objective of this study was to evaluate whether P(bt)O2 more closely reflects variables related to cerebral oxygen diffusion or reflects cerebral oxygen delivery and metabolism...
  19. ncbi request reprint Continuous monitoring of the microcirculation in neurocritical care: an update on brain tissue oxygenation
    Jack C Rose
    Neurovascular Service, University of California, San Francisco, California 94110, USA
    Curr Opin Crit Care 12:97-102. 2006
    ..This article summarizes recent clinical and experimental studies of parenchymal brain tissue oxygen monitoring and considers future directions for its use in neurocritical care...
  20. ncbi request reprint External validation of the ICH score
    Jennifer L Clarke
    Department of Neurology, University of California, San Francisco, and San Francisco General Hospital, CA 94110, USA
    Neurocrit Care 1:53-60. 2004
    ..The purpose of this study was to determine whether the ICH score accurately risk-stratifies patients in an independent cohort...
  21. doi request reprint The new Licox combined brain tissue oxygen and brain temperature monitor: assessment of in vitro accuracy and clinical experience in severe traumatic brain injury
    Campbell Stewart
    Department of Surgery, San Francisco General Hospital, University of California, San Francisco, San Francisco, California 94110, USA
    Neurosurgery 63:1159-64; discussion 1164-5. 2008
    ..We also describe our clinical experience with the Licox PMO probe...
  22. doi request reprint Intracerebral hemorrhage
    Lucas Elijovich
    Department of Neurology, University of California San Francisco, San Francisco General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110, USA
    Semin Neurol 28:657-67. 2008
    ..Ongoing clinical trials are investigating surgical evacuation of lobar hemorrhage, minimally invasive surgical hematoma evacuation, and aggressive blood pressure lowering...
  23. ncbi request reprint Advanced cerebral monitoring in neurocritical care
    Nobl Barazangi
    Department of Neurology, University of California, San Francisco and Neurocritical Care Program, San Francisco General Hospital, California 94110, USA
    Neurol India 56:405-14. 2008
    ....
  24. doi request reprint The role of lung function in brain tissue oxygenation following traumatic brain injury
    Guy Rosenthal
    Department of Neurosurgery, University of California, San Francisco, California, USA
    J Neurosurg 108:59-65. 2008
    ..The purpose of this study was to investigate the influence of lung function on PbtO2 with an oxygen challenge (increase in fraction of inspired oxygen [FiO2] concentration to 1.0)...
  25. ncbi request reprint Small-volume resuscitation with HBOC-201: effects on cardiovascular parameters and brain tissue oxygen tension in an out-of-hospital model of hemorrhage in swine
    Seong K Lee
    San Francisco Injury Center, University of California, San Francisco, School of Medicine, San Francisco, CA, USA
    Acad Emerg Med 9:969-76. 2002
    ....
  26. ncbi request reprint Initial Glasgow Coma Scale score predicts outcome following thrombolysis for posterior circulation stroke
    Jack W Tsao
    Department of Neurology, San Francisco General Hospital, San Francisco, Calif, USA
    Arch Neurol 62:1126-9. 2005
    ..Consequently, there is less published information on thrombolytic therapy for posterior circulation stroke...
  27. ncbi request reprint Relationship between brain tissue oxygen tension and CT perfusion: feasibility and initial results
    J Claude Hemphill
    Department of Neurology, University of California, San Francisco, CA 94110, USA
    AJNR Am J Neuroradiol 26:1095-100. 2005
    ..The purpose of this study was to determine if there is a relationship between CT perfusion (CTP) imaging parameters and P(br)O(2)...
  28. pmc Charlson comorbidity index adjustment in intracerebral hemorrhage
    Barak Bar
    Department of Neurology, Brain and Spinal Injury Center, University of California, San Francisco, and Room 4M62, San Francisco General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110, USA
    Stroke 42:2944-6. 2011
    ..The purpose of this study was to assess whether the Charlson Comorbidity Index (CCI) was associated with early mortality and long-term functional outcome in patients with intracerebral hemorrhage...
  29. ncbi request reprint Stroke thrombolysis in the elderly: risk or benefit?
    J Claude Hemphill
    Neurology 65:1690-1. 2005
  30. pmc Prevalence and prognosis of coexistent asymptomatic intracranial stenosis
    Fadi Nahab
    Stroke 39:1039-41. 2008
    ..There are limited data on the prevalence and prognosis of asymptomatic intracranial stenosis (AIS)...
  31. ncbi request reprint Core curriculum and competencies for advanced training in neurological intensive care: United Council for Neurologic Subspecialties guidelines
    Stephan A Mayer
    United Council for Neurologic Subspecialties, St Paul, MN 55116, USA
    Neurocrit Care 5:159-65. 2006
  32. ncbi request reprint Treating warfarin-related intracerebral hemorrhage: is fresh frozen plasma enough?
    J Claude Hemphill
    Stroke 37:6-7. 2006
  33. ncbi request reprint Program requirements for fellowship training in neurological intensive care: United Council for Neurologic Subspecialties guidelines
    Stephan A Mayer
    United Council for Neuroloic Subspecialties, St Paul, MN 55116, USA
    Neurocrit Care 5:166-71. 2006
  34. ncbi request reprint The need for a registry renaissance in neurocritical care
    J Claude Hemphill
    Crit Care Med 35:2208-9. 2007
  35. ncbi request reprint Small-volume resuscitation with the hemoglobin substitute HBOC-201: effect on brain tissue oxygenation
    Geoffrey T Manley
    School of Medicine, University of California San Francisco, San Francisco Injury Center, Department of Neurological Surgery, USA
    Adv Exp Med Biol 530:311-7. 2003
    ..To investigate the effects of small-volume resuscitation with a hemoglobin based oxygen carrier on brain tissue oxygen tension (PbrO2) in hemorrhaged swine...

Research Grants3

  1. Secondary Brain Injury in Intracerebral Hemorrhage
    JESSE HEMPHILL; Fiscal Year: 2005
    ..In conjunction with the didactic training and mentoring undertaken, this program will foster Dr. Hemphill's development into an independent researcher in neurologic critical care, specifically focusing on intracerebral hemorrhage. ..
  2. SF-NET: San Francisco Neurological Emergencies Trials Network
    JESSE HEMPHILL; Fiscal Year: 2007
    ..A network to conduct streamlined trials for these conditions can bring new treatments to clinical care more rapidly. ..